Raman spectrum oral cavity tumor pathological diagnosis analyzer

Abstract

The utility model discloses a Raman spectrum oral cavity tumor pathological diagnosis analyzer, which belongs to the technical field of clinical application and comprises a spectrum diagnosis device and a sampling table, the sampling table is mounted on a storage cabinet, a cabinet door is mounted on the storage cabinet, a feed opening communicated with the inside of the storage cabinet is arranged on the sampling table, and an annular conveying mechanism is mounted in the storage cabinet. A plurality of storage boxes are placed on the annular conveying mechanism, each storage box is conveyed through the annular conveying mechanism to pass through the lower portion of the discharging opening, and a heat exchanger is further installed in the storage cabinet and electrically connected with the temperature controller. The discharge port is communicated with the storage cabinet, so that tissue samples sampled by the sampling table can be placed in the storage boxes for storage, and the plurality of storage boxes are conveyed by the annular conveying mechanism to pass through the lower part of the discharge port, so that the tissue samples can accurately fall into the storage boxes; and a plurality of tissue samples can be stored more conveniently and quickly.

Description

TECHNICAL FIELD

[0001] The utility model relates to clinical application technical field, especially a kind of Raman spectrum oral tumor pathological diagnosis analyzer. BACKGROUND

[0002] Oral squamous carcinoma is one of the most common head and neck tumors, which has a significant impact on patient survival rate. Early detection and rapid diagnosis of oral squamous carcinoma are crucial for improving patient survival rate and prognosis. Current diagnostic techniques for oral squamous carcinoma mainly include pathological biopsy, imaging examination (such as CT, MRI, PET), endoscopy, cytology, and spectral analysis techniques (such as Raman spectroscopy). Spectral analysis techniques have gained widespread attention due to their convenience and speed. In recent years, Raman spectroscopy has shown great potential in the diagnosis of oral squamous carcinoma. Raman spectroscopy uses scattered light generated by the interaction of light and matter to identify differences in molecular composition and structure of tissues. This technique is non-invasive, fast, and highly sensitive, and can achieve efficient detection and diagnosis of cancerous tissues with deep learning algorithms.

[0003] After identifying cancerous tissues using a Raman spectroscopy diagnostic instrument, the tissue in the area needs to be sampled. When there are multiple sampling locations for a patient, the types of tissue samples generated are also more numerous, and each sample needs to be stored separately. However, traditional Raman spectroscopy diagnostic instruments lack sample storage devices. If the tissue cells are not immediately sent to the storage device after sampling, the key components in the cells can denature and be destroyed. This requires additional storage devices or manual transportation, neither of which is conducive to improving the work efficiency of medical personnel. Therefore, traditional Raman spectroscopy diagnostic instruments still have some defects in use. SUMMARY

[0004] The utility model aims to solve the problem of inconvenient storage of samples that cannot be immediately and conveniently processed after diagnosis by traditional Raman spectrometers, and provides a Raman spectroscopy oral tumor pathological diagnosis analyzer, which has the advantages of automatic and separate storage of samples, convenience, and reduction of workload for medical personnel.

[0005] To achieve the above-mentioned purpose, the utility model adopts the technical scheme of:

[0006] The utility model provides a kind of Raman spectrum oral tumor pathological diagnosis analyzer, including spectral diagnosis device and sampling table, the sampling table is installed on storage cabinet, the storage cabinet is installed on cabinet door, sampling table is opened with the lower discharge port of the inside communication of storage cabinet, annular conveying mechanism is installed in the storage cabinet, a plurality of storage boxes are placed on the annular conveying mechanism, each storage box is conveyed from the lower discharge port below by the annular conveying mechanism, heat exchanger is also installed in the inside of the storage cabinet, and the heat exchanger is electrically connected with temperature controller.

[0007] Preferably, two symmetrically arranged discharge baffles are installed on the discharge port, and the discharge baffles are hingedly connected to the inner wall of the discharge port on the side away from each other.

[0008] Preferably, a plurality of fixing frames are arranged on the annular conveying mechanism, the storage boxes are matched with the specifications of the fixing frames, and the storage boxes are movably installed on the fixing frames.

[0009] Preferably, the annular conveying mechanism includes two rollers, the rollers are driven by a motor, and a transmission chain is sleeved between the rollers, and the fixing frames are installed on the transmission chain through connecting frames.

[0010] Preferably, the heat exchanger is installed at the middle position of the annular conveying mechanism, and the storage boxes move around the heat exchanger.

[0011] Preferably, the spectral diagnosis device includes a host computer, a display screen, a spectrometer and a laser.

[0012] Compared with the prior art, the utility model has the following beneficial effects:

[0013] 1. The discharge port is communicated with the storage cabinet, so that the tissue samples taken by the sampling table can be placed in the storage boxes for storage, and the storage boxes are arranged to pass through the lower discharge port below the annular conveying mechanism, so that the tissue samples can be accurately dropped into the storage boxes, and the multiple tissue samples can be conveniently and quickly stored.

[0014] 2. The fixing frames are installed on the transmission chain of the annular conveying mechanism, and the storage boxes are placed on the fixing frames, so that the storage boxes can be accurately stopped below the discharge port.

[0015] 3. The two symmetrically arranged discharge baffles are arranged on the discharge port, and the discharge baffles are controlled to be inclined downward by the discharge cylinder, so that the tissue samples can slowly slide into the storage boxes along the slope of the discharge baffles, and the collision of the tissue samples when falling is avoided. BRIEF DESCRIPTION OF DRAWINGS

[0016] Figure 1 It is a whole structure schematic view of the Raman spectrometer of the utility model.

[0017] Figure 2 It is a inside structure schematic view of the storage cabinet of the utility model.

[0018] Figure 3 It is a structure schematic view of the fixed frame installed on the annular conveying mechanism of the utility model.

[0019] In the drawing: 1, storage cabinet, 2, main machine, 3, display screen, 4, spectrometer, 5, laser, 6, sampling table, 7, cabinet door, 8, discharging port, 9, discharging plate, 10, hinge, 11, discharging cylinder, 12, annular conveying mechanism, 13, heat exchanger, 14, fixed frame, 15, storage box, 16, connecting frame, 17, roller shaft, 18, transmission chain. DETAILED DESCRIPTION

[0020] In order to make the technical means, creative features, purposes and effects of the utility model easy to understand, the utility model is further described below in combination with specific embodiments.

[0021] As shown in Figure 1 and Figure 2 , a Raman spectrum oral tumor pathological diagnosis analyzer, comprising a spectrum diagnosis device and a sampling table 6, the sampling table 6 is installed on the storage cabinet 1, the cabinet door 7 is installed on the storage cabinet 1, the discharging port 8 in communication with the inside of the storage cabinet 1 is formed on the sampling table 6, the annular conveying mechanism 12 is installed in the storage cabinet 1, a plurality of storage boxes 15 are placed on the annular conveying mechanism 12, each storage box 15 is conveyed from below the discharging port 8 through the annular conveying mechanism 12, the heat exchanger 13 is further installed in the inside of the storage cabinet 1, and the heat exchanger 13 is electrically connected with the temperature controller. The spectrum diagnosis device and the sampling table 6 are both installed on the storage cabinet 1, and the sampling table 6 is located on one side of the spectrum diagnosis device, which is convenient for sampling after diagnosis, the discharging port 8 on the sampling table 6 is used to conveniently drop the tissue sample into the storage box 15, the annular conveying mechanism 12 in the storage cabinet 1 is used to convey the storage box 15 to the position directly below the discharging port 8, and the tissue sample can accurately drop into the storage box 15 through the discharging port 8. The annular conveying mechanism 12 is used as a transmission piece, so that a sufficient number of storage boxes 15 can be conveyed to the position below the discharging port 8 when a plurality of tissue samples need to be sampled, and a large space is not occupied, so that the annular conveying track can ensure that all the storage boxes 15 can pass below the discharging port 8. The heat exchanger 13 is further arranged in the storage cabinet 1, and the temperature controller is used to control the heat exchanger 13 to maintain a constant temperature in the storage cabinet 1, so that the tissue sample can be stored for a long time.

[0022] In order to conveniently drop the tissue sample from the discharging port 8, as shown in Figure 2As shown, two symmetrically arranged feeding baffles 9 are installed on the feeding port 8. The sides of the feeding baffles 9 that are far apart from each other are installed on the inner wall of the feeding port 8 via hinges 10. A feeding cylinder 11 is installed at the bottom of the feeding baffles 9. After sampling, the tissue sample can be placed in a disposable storage bag and then fall from the feeding port 8 into the storage box 15. This will not contaminate the sample or the feeding baffles 9. The feeding port 8 controls whether the tissue sample falls by setting the feeding baffles 9, thereby realizing automated feeding. There are two feeding baffles 9, which are arranged symmetrically. When feeding, the feeding cylinder 11 pulls the feeding baffles 9 and tilts them downwards. The two feeding baffles 9 gradually form symmetrical slopes. The tissue sample can fall into the slopes first. The opening of the symmetrical slopes is narrow at the bottom and wide at the top. As the feeding cylinder 11 continues to work, the opening at the bottom gradually widens, and finally the tissue sample falls into the storage box 15. During this process, the tissue sample will not expand violently inside the storage box 15, ensuring the integrity of the tissue.

[0023] To ensure the precise stopping position of the conveyor belt 15, such as Figure 3 As shown, the annular conveyor mechanism 12 is also equipped with several fixed frames 14. The storage box 15 is matched with the specifications of the fixed frame 14, and the storage box 15 is movably installed on the fixed frame 14. The fixed frame 14 and the annular conveyor mechanism 12 are relatively fixed in position. In this way, the conveying process of the annular conveyor mechanism 12 can be preset so that the annular conveyor mechanism 12 stops working when each fixed frame 14 reaches exactly below the discharge port 8. Therefore, with the positioning of the fixed frame 14, after the storage box 15 is placed on the fixed frame 14, it can be accurately moved to the direct below the discharge port 8 for the preservation of tissue samples. In addition, the fixed frame 14 provides a fixed placement position for the storage box 15, and no correction is required when taking out or putting in the storage box 15, which will not affect the next use. The annular conveyor mechanism 12 includes two rollers 17, which are driven by a motor and connected by a transmission chain 18. A fixed frame 14 is mounted on the transmission chain 18 via a connecting frame 16. The operating principle of the annular conveyor mechanism 12 is that the motor drives the rollers 17 to rotate, causing both rollers 17 to rotate simultaneously, which in turn drives the transmission chain 18 to move relative to the rollers 17. The fixed frame 14 is set on the transmission chain 18, so the fixed frame 14 and the transmission chain 18 are relatively stationary. Since the number of rotations of the rollers 17 is constant each time, the moving distance of the fixed frame 14 is also constant, thus enabling it to position the storage box 15.

[0024] In order to ensure that the heat exchanger 13 does not occupy too much space in the storage cabinet 1, the heat exchanger 13 is installed in the middle position of the annular conveying mechanism 12. The storage box 15 moves around the heat exchanger 13. Since the center of the annular conveying mechanism 12 is a central control structure, installing the heat exchanger 13 in the middle position not only ensures that it is close to the storage box 15 and minimizes temperature transfer loss, but also saves space.

[0025] As Figure 1 shown, the spectral diagnostic device comprises a host computer 2, a display screen 3, a spectrometer 4 and a laser 5, the host computer 2 loads a display program, the analysis structure of the spectrometer 4 is displayed through the display screen 3, and the laser 5 is used to emit laser to contact with human tissue to form scattered light spectrum received and analyzed by the spectrometer 4.

[0026] It is obvious for those skilled in the art that the present application is not limited to the details of the above exemplary embodiments, and can be implemented in other specific forms without departing from the spirit or essential characteristics of the present application. Therefore, the embodiments should be regarded as exemplary and non-limiting, and the scope of the present application is defined by the appended claims rather than the above description, and all changes falling within the meaning and scope of the equivalent elements of the claims are intended to be included in the present application. Any reference signs in the claims should not be regarded as limiting the claims involved.

[0027] In addition, it should be understood that, although the present specification is described in terms of embodiments, not every embodiment contains only one independent technical solution, and the description of the specification is only for the sake of clarity, and those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can be properly combined to form other embodiments that those skilled in the art can understand.

Claims

1. A Raman spectrum oral tumor pathological diagnosis analyzer, comprising a spectrum diagnosis device and a sampling table (6), characterized in that, The sampling table (6) is installed on the storage cabinet (1), the cabinet door (7) is installed on the storage cabinet (1), the sampling table (6) is provided with the discharging port (8) communicated with the inside of the storage cabinet (1), the annular conveying mechanism (12) is installed in the storage cabinet (1), a plurality of storage boxes (15) are placed on the annular conveying mechanism (12), each storage box (15) is conveyed to pass below the discharging port (8) through the annular conveying mechanism (12), the heat exchanger (13) is further installed in the inside of the storage cabinet (1), and the heat exchanger (13) is electrically connected with the temperature controller.

2. The Raman spectroscopy oral tumor pathological diagnosis analyzer according to claim 1, characterized in that, Two symmetrically arranged discharging baffles (9) are installed on the discharging port (8), the sides of the discharging baffles (9) away from each other are both hingedly connected to the inner wall of the discharging port (8), and the bottom of the discharging baffle (9) is provided with a discharging cylinder (11).

3. The Raman spectroscopy oral tumor pathological diagnosis analyzer according to claim 1, characterized in that, A plurality of fixing frames (14) are further arranged on the annular conveying mechanism (12), the storage box (15) is matched with the specification of the fixing frame (14), and the storage box (15) is movably installed on the fixing frame (14).

4. The Raman spectroscopy oral tumor pathological diagnosis analyzer according to claim 3, characterized in that, The annular conveying mechanism (12) comprises two roller shafts (17), the roller shafts (17) are driven by a motor, and a transmission chain (18) is sleeved between the roller shafts (17), and the fixing frame (14) is installed on the transmission chain (18) through a connecting frame (16).

5. The Raman spectroscopy oral tumor pathological diagnosis analyzer according to claim 1, characterized in that, The heat exchanger (13) is installed at the middle position of the annular conveying mechanism (12), and the storage box (15) moves around the heat exchanger (13).

6. The Raman spectroscopy oral tumor pathological diagnosis analyzer according to claim 1, characterized in that, The spectrum diagnostic device comprises a host computer (2), a display screen (3), a spectrometer (4) and a laser (5).

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