Efficient defoaming and stirring device for fusidic acid fermentation
By designing a highly efficient defoaming and stirring device with a buoyancy chamber and defoaming blades, the problem of poor defoaming effect during fusidic acid fermentation was solved, achieving efficient elimination of bubbles and stability of the fermentation process, improving dissolved oxygen value and saving energy.
Patent Information
- Application Number
- CN202423166295.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-23
- Publication Date
- 2026-02-06
- Estimated Expiration
- 2034-12-23
AI Technical Summary
Existing stirring devices are not effective at defoaming during fusidic acid fermentation, which increases the risk of bubbles overflowing and material escaping for contamination.
A high-efficiency defoaming and stirring device including a buoyancy chamber and defoaming blades was designed. The position of the buoyancy chamber is automatically adjusted and the height of the defoaming blades is controlled by the connection port. Different shapes of defoaming blades (cup-shaped, flat, comb-shaped, and mesh-shaped) are combined to adapt to different liquid properties and achieve high-efficiency defoaming.
This effectively prevents bubbles from rising to the top, increases the contact rate between the liquid and air, reduces the stirring rate to save energy, and ensures the stability of the fermentation process and the integrity of the product.
Smart Images
Figure CN223879735U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to fermentation engineering technical field especially, it relates to a high -efficient defoaming stirring device for fusidic acid fermentation. BACKGROUND
[0002] In the fermentation process of fusidic acid, the stirring system can make the fermentation broth fully mixed, ensure that the nutrients, oxygen and microorganisms in the fermentation broth are uniformly distributed. Through stirring, local concentration difference and temperature difference of the fermentation broth can be avoided, and a stable environment is provided for the growth and metabolism of microorganisms. The fermenter includes a tank body, a stirring system, a temperature control system, a ventilation system, a pressure monitoring and safety device, a precise feeding and discharging system, etc. to meet various needs in the fermentation process and ensure efficient, stable and safe fermentation. In terms of structural design, the tank body material needs to be corrosion-resistant and have sufficient mechanical strength, usually in a cylindrical structure, with good connection and sealing, an opening at the top of the tank and a convenient discharge at the bottom. The stirring system selects appropriate stirring paddle type according to the material properties, with corrosion-resistant and sufficient strength, equipped with power device and adjustable stirring speed. The temperature control is through jacket or coil heating and cooling, and the temperature is precisely adjusted by temperature sensor and automatic control system. The ventilation system has bubble ventilation and micropore ventilation, and the gas needs to be filtered by multiple stages to ensure purity and sterility.
[0003] In the fermentation process of fusidic acid, a large amount of bubbles is often produced due to the metabolic activity of microorganisms in the fermentation broth and the stirring, ventilation and other operations. If these bubbles are not treated in time, they will have many adverse effects on the fermentation process. First, the bubbles will occupy the space of the fermenter, reduce the effective volume of the fermentation broth and affect the fermentation efficiency. Second, the bubbles will affect the mixing effect of the fermentation broth, leading to uneven distribution of nutrients and oxygen and affecting the growth and metabolism of microorganisms. In addition, the bubbles may also carry the products in the fermentation broth, causing product loss. Therefore, a defoaming device needs to be introduced in the fermentation process of fusidic acid. The existing stirring device has poor defoaming effect, and the bubbles are prone to overflow during the fermentation process, increasing the risk of material loss and bacterial contamination. Therefore, in view of the above phenomenon, a high-efficiency defoaming stirring device for fusidic acid fermentation is proposed to meet the needs of actual use. SUMMARY
[0004] The utility model provides a high -efficient defoaming stirring device for fusidic acid fermentation, solves the technical problem that the existing stirring device is poor in defoaming effect.
[0005] To solve the above-mentioned technical problems, this utility model provides a high-efficiency defoaming and stirring device for fusidic acid fermentation, including a fermentation tank body. The surface of the fermentation tank body is covered with a temperature regulating cover, and the bottom of the temperature regulating cover is provided with a support leg. A reduction motor is provided on the top of the fermentation tank body. The output end of the reduction motor is fixedly fitted with a stirring spindle. Stirring blades and a defoaming component are rotatably mounted on the surface of the stirring spindle. The defoaming component includes a buoyancy chamber, which is movably fitted onto the surface of the stirring spindle. A connecting rod is provided on the side of the buoyancy chamber, and a defoaming blade is fixedly installed at one end of the connecting rod.
[0006] In some embodiments, the number of stirring blades is four, and the four stirring blades are equidistantly distributed on the bottom surface of the stirring main shaft.
[0007] In some embodiments, the buoyancy cavity includes a cavity body, which is a hollow annular shape. A bushing is fixedly fitted in the middle of the cavity body. A guide bar is integrally formed on the side of the stirring spindle. A groove matching the guide bar is formed on the inner wall of the bushing. The bushing is movably fitted onto the surface of the stirring spindle through the cooperation of the groove and the guide bar.
[0008] In some embodiments, the top of the cavity is provided with a connecting pipe port, the surface of the connecting pipe port is threaded with a sealing cap, the bottom of the sealing cap is fitted to the top of the cavity through a sealing gasket, and the bottom of the connecting pipe port is provided with a water supply pipe.
[0009] In some embodiments, the connecting rod includes a threaded post, one end of which is threadedly fitted with a threaded sleeve, and the other end of which is fixedly mounted on the side of the buoyancy cavity. A hexagonal nut is threadedly fitted onto the surface of the threaded post, and the side of the hexagonal nut fits against the side of the threaded sleeve. The defoaming blade is fixedly mounted on one end of the threaded sleeve.
[0010] In some embodiments, the number of connecting rods is several, and the several connecting rods are evenly arrayed on the side of the buoyancy cavity.
[0011] In some embodiments, the connecting rod is located on the upper side of the buoyancy cavity, and the defoaming blade is flush with the liquid surface in the fermenter body.
[0012] In some embodiments, the lower end of the stirring spindle is provided with a shoulder, which is located below the guide bar, and a limit screw is threaded on the surface of the stirring spindle, which is located above the guide bar.
[0013] In some embodiments, the defoaming blades are any one of cup-shaped, flat-shaped, comb-shaped, or mesh-shaped.
[0014] Compared with the related art, the high-efficiency defoaming stirring device for fusidic acid fermentation has the following beneficial effects:
[0015] The utility model provides a high -efficient defoaming stirring device for fusidic acid fermentation, and the gas that annular distributor sprays and the material liquid in fermentation tank pass through the stirring of stirring vane, and the material liquid stirring is more even and reasonable, and the effective contact rate of material liquid and air is improved, thereby improving the dissolved oxygen value, at this moment can reduce the stirring rate to save the energy consumption, through the defoaming subassembly of setting eliminates the foam on liquid level, can effectively avoid the situation of producing gas bubble and escaping material and bacteria during fermentation.
[0016] The utility model provides a high -efficient defoaming stirring device for fusidic acid fermentation, through the buoyancy chamber of setting makes defoaming subassembly can follow liquid level height automatic regulation position, always keeps defoaming paddle and can effectively eliminate the gas bubble of liquid level, and through the connecting pipe mouth of setting can inject a certain amount of pure water in cavity, to change the weight of buoyancy chamber, thereby control defoaming paddle and the height of liquid level, to keep the maximum defoaming efficiency. DRAWINGS
[0017] Figure 1 It is the whole structure schematic diagram of the utility model;
[0018] Figure 2 It is the defoaming subassembly structure schematic diagram of the utility model;
[0019] Figure 3 It is the defoaming subassembly cross section structure schematic diagram of the utility model;
[0020] Figure 4 It is the defoaming subassembly installation structure three -dimensional schematic diagram of the utility model.
[0021] Marked number in drawing: 1, fermentation tank body;2, temperature adjusting cover;3, support leg;4, speed reducer motor;5, stirring main shaft;6, stirring vane;7, defoaming subassembly;8, annular distributor;51, guide strip;52, limit screw;71, buoyancy chamber;72, connecting rod;73, defoaming paddle;711, cavity;712, shaft sleeve;713, connecting pipe mouth;714, sealing cover;715, water delivery pipe;721, threaded column;722, threaded sleeve;723, hexagonal nut. SPECIFIC EMBODIMENT
[0022] Example one
[0023] This embodiment provides a kind of high-efficiency defoaming stirring device for fusidic acid fermentation, as Figure 1As shown, the utility model of body 1 of fermentation tank, the surface of body 1 of fermentation tank is wrapped with temperature regulation cover 2, and temperature regulation cover 2 is equipped with support leg 3 at the bottom, and body 1 of fermentation tank is equipped with speed reducer motor 4 at the top, and the output end of speed reducer motor 4 is fixedly sleeved with stirring main shaft 5, and the surface of stirring main shaft 5 is rotatably installed with stirring blade 6 and defoaming assembly 7 respectively, and the inner chamber bottom of body 1 of fermentation tank is equipped with annular distributor 8.
[0024] In the embodiment, the gas sprayed by annular distributor 8 and the material liquid in the fermentation tank are stirred by stirring blade 6, the material liquid is more uniformly and reasonably stirred, the effective contact rate of the material liquid and air is improved, thereby the dissolved oxygen value is improved, at this time, the stirring rate can be reduced to save energy consumption, the foam on the liquid surface is eliminated by the defoaming assembly 7, the situation that gas bubble is produced and escapes in the fermentation process is effectively avoided.
[0025] Example Two
[0026] On the basis of example one, as shown, Figure 2 The defoaming assembly 7 of the embodiment includes buoyancy cavity 71, and the buoyancy cavity 71 is movably sleeved on the surface of stirring main shaft 5, and the side surface of buoyancy cavity 71 is provided with connecting rod 72, and one end of connecting rod 72 is fixedly installed with defoaming paddle 73.
[0027] In the embodiment, the buoyancy cavity 71 is arranged, so that the defoaming assembly 7 can automatically adjust the position following the liquid level height, and the defoaming paddle 73 can effectively eliminate the gas bubble on the liquid surface at all times.
[0028] Example Three
[0029] On the basis of example one, as shown, Figures 1-2 The number of stirring blade 6 of the embodiment is four, and the four stirring blades 6 are equidistantly distributed on the bottom end surface of stirring main shaft 5.
[0030] In the embodiment, the four stirring blades 6 are arranged to increase the effective contact rate of the material liquid and air, thereby further improving the dissolved oxygen value.
[0031] Example Four
[0032] On the basis of example one, as shown, Figure 3 The buoyancy cavity 71 of the embodiment includes cavity body 711, and the cavity body 711 is hollow annular, and the middle part of cavity body 711 is fixedly sleeved with shaft sleeve 712, and the side surface of stirring main shaft 5 is integrally formed with guide strip 51, and the inner wall of shaft sleeve 712 is provided with recess matched with guide strip 51, and shaft sleeve 712 is movably sleeved on the surface of stirring main shaft 5 through the cooperation of recess and guide strip 51.
[0033] In this embodiment, the stirring spindle 5, through the cooperation of the guide bar 51 and the groove, can not only drive the buoyancy chamber 71 to rotate, but also allow the buoyancy chamber 71 to move up and down on the surface of the stirring spindle 5 to adapt to different liquid levels.
[0034] Example 5
[0035] Based on Example 1, such as Figure 3 As shown, the top of the cavity 711 in this embodiment is provided with a connecting pipe port 713, and a sealing cap 714 is threadedly installed on the surface of the connecting pipe port 713. The bottom of the sealing cap 714 is attached to the top of the cavity 711 through a sealing gasket, and a water supply pipe 715 is provided at the bottom of the connecting pipe port 713.
[0036] In this embodiment, the density of the liquid in the fermentation tank varies due to differences in the raw material composition. A certain amount of pure water can be injected into the cavity 711 through the connection port 713 to change the weight of the buoyancy cavity 71, thereby controlling the height of the defoaming blade 73 above the liquid surface to maintain the maximum defoaming efficiency.
[0037] Example 6
[0038] Based on Example 1, such as Figure 3 As shown, the connecting rod 72 in this embodiment includes a threaded post 721. One end of the threaded post 721 is threadedly fitted with a threaded sleeve 722, and the other end of the threaded post 721 is fixedly installed on the side of the buoyancy cavity 71. A hexagonal nut 723 is threadedly fitted on the surface of the threaded post 721. The side of the hexagonal nut 723 fits against the side of the threaded sleeve 722. The defoaming blade 73 is fixedly installed on one end of the threaded sleeve 722.
[0039] In this embodiment, by adjusting the total length of the threaded sleeve 722 and the threaded post 721 and fastening them with the hexagonal nut 723, different defoaming blades 73 can be distributed in different positions. When rotating, they can eliminate foam in different positions, improve the defoaming effect, and the tilt angle of the defoaming blades 73 can be adjusted to test the optimal defoaming angle.
[0040] Example 7
[0041] Based on Example 1, such as Figure 4 As shown, in this embodiment, there are several connecting rods 72, and these connecting rods 72 are evenly arrayed on the side of the buoyancy cavity 71.
[0042] In this embodiment, several connecting rods 72 are connected to several defoaming blades 73 to improve the defoaming effect.
[0043] Example 8
[0044] Based on Example 1, such asFigures 1-2 As shown, the connecting rod 72 of the embodiment is located on the upper side of the buoyancy chamber 71, and the defoaming paddle 73 is flush with the liquid surface in the fermentation tank body 1.
[0045] In the embodiment, the buoyancy chamber 71 is made of stainless steel and has a certain weight. The connecting rod 72 is arranged on the upper side, so that the buoyancy chamber 71 has a larger sinking space in the material liquid, and is suitable for a wider range of material liquids in density.
[0046] Example Nine
[0047] On the basis of example one, as shown in Figure 2 , 4 As shown, the lower end of the stirring spindle 5 of the embodiment is provided with a shaft shoulder, which is arranged below the guide bar 51. The surface of the stirring spindle 5 is provided with a limiting screw 52, which is arranged above the guide bar 51.
[0048] In the embodiment, the shaft shoulder and the limiting screw 52 limit the upper and lower positions of the buoyancy chamber 71 respectively, so as to avoid collision between the defoaming paddle 73 and the inside of the fermentation tank.
[0049] Example Ten
[0050] On the basis of example one, the defoaming paddle 73 of the embodiment is any one of cup-shaped, flat-plate-shaped, comb-tooth-shaped, and net-shaped.
[0051] In the embodiment, the defoaming paddles 73 of different shapes have their own unique defoaming principles and application scenarios. The cup-shaped defoaming paddle 73 gathers bubbles to the central area by centrifugal force when rotating, so that the bubbles are squeezed and broken, and is suitable for processing material liquids with medium viscosity; the flat-plate-shaped defoaming paddle 73 mainly relies on direct collision with bubbles and shear force on liquid to defoam, and is suitable for low-viscosity material liquids; the comb-tooth-shaped defoaming paddle 73 can penetrate into the foam layer, divide the bubbles into smaller parts, and enhance the shear and squeezing action on the bubbles, and is suitable for processing high-viscosity material liquids that are prone to generate stable foam; the net-shaped defoaming paddle 73 increases the contact area with foam by using a larger surface area, so that the foam enters the mesh hole and is broken by squeezing and shearing when rotating, and also plays a certain role in filtering impurities, and is suitable for occasions that require fine defoaming and impurity filtering. Users can select appropriate shapes of the defoaming paddle 73 according to the properties of the material liquid in the fermentation tank and specific defoaming requirements, so as to improve the defoaming efficiency and fermentation quality.
[0052] Working principle: the gas sprayed by the annular distributor 8 and the liquid in the fermenter pass through the stirring of the stirring blade 6, the liquid stirring is more uniform and reasonable, the effective contact rate of the liquid and air is improved, thereby the dissolved oxygen value is improved, at this time the stirring speed can be reduced to save energy, the foam on the liquid surface is eliminated through the setting of the defoaming assembly 7, the gas bubble blowout, the material escaping and the bacterial infection in the fermentation process can be effectively avoided; through the setting of the buoyancy cavity 71, the defoaming assembly 7 can automatically adjust the position following the liquid level height, the defoaming blade 73 can always effectively eliminate the gas bubble on the liquid surface, and through the setting of the connecting pipe 713, a certain amount of pure water can be injected into the cavity 711 to change the weight of the buoyancy cavity 71, thereby the height of the defoaming blade 73 and the liquid surface is controlled, and the maximum defoaming efficiency is maintained.
Claims
1. A high-efficiency defoaming stirring device for fursidic acid fermentation tank body, characterized in that: The surface of the fermenter body is wrapped with a temperature adjusting cover, the bottom of the temperature adjusting cover is provided with supporting legs, the top of the fermenter body is provided with a speed reducer motor, the output end of the speed reducer motor is fixedly sleeved with a stirring main shaft, the surface of the stirring main shaft is rotatably installed with stirring blades and a defoaming assembly respectively; the defoaming assembly comprises a buoyancy cavity, the buoyancy cavity is movably sleeved on the surface of the stirring main shaft, the side surface of the buoyancy cavity is provided with a connecting rod, one end of the connecting rod is fixedly installed with a defoaming paddle.
2. A high-efficiency defoaming stirring device for fumaric acid fermentation according to claim 1, characterized in that, The number of the stirring blades is four, and the four stirring blades are equidistantly distributed on the bottom end surface of the stirring main shaft.
3. The high-efficiency defoaming stirring device for fursulfa fermentation according to claim 1, characterized in that, The number of the connecting rods is several, and the several connecting rods are uniformly arrayed on the side surface of the buoyancy cavity.
4. The high-efficiency defoaming stirring device for fursulfa fermentation according to claim 1, characterized in that, The connecting rod is located on the upper side surface of the buoyancy cavity, and the defoaming paddle is flush with the liquid surface in the fermenter body.
5. The high-efficiency defoaming stirring device for fumaric acid fermentation according to claim 1, characterized in that, The lower end of the stirring main shaft is provided with a shaft shoulder, the shaft shoulder is arranged below the guide strip, the surface of the stirring main shaft is threadedly installed with a limiting screw, and the limiting screw is arranged above the guide strip.
6. A high-efficiency defoaming stirring device for fumaric acid fermentation according to claim 1, characterized in that, The defoaming paddle is any one of a cup shape, a flat plate shape, a comb tooth shape and a mesh shape.