Cell suspension subpackaging device

By designing a cell suspension dispensing device, which utilizes motor-driven rotation and a spring structure, the problems of sedimentation and air bubbles after cell suspension has been solved, achieving uniform and high-purity dispensing of cell suspension and ensuring the accuracy of experimental results.

CN223892723UActive Publication Date: 2026-02-10LUOYANG JIANTE PHARM CO LTD
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Patent Information

Application Number
CN202520106023.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-01-17
Publication Date
2026-02-10
Estimated Expiration
2035-01-17

AI Technical Summary

Technical Problem

Cell suspensions accumulate sediment after standing, leading to differences in cell content among different samples and affecting the accuracy of experimental results. Furthermore, excessive shaking can cause air bubbles to form and damage cells.

Method used

A cell suspension dispensing device is used. A first motor drives the connecting shaft and rotating disk to rotate, which in turn drives the push rod to shake slightly to ensure that the cell suspension is mixed evenly. A second motor drives the dispensing frame to rotate, and a spring pushes the moving sleeve to reduce the contact between the dispensing head and the air, thereby reducing the possibility of contaminants entering.

Benefits of technology

It achieves uniform mixing of cell suspension, avoids bubble formation, protects cell integrity, and reduces the entry of external contaminants, ensuring the purity and quality of the cell suspension.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a cell suspension subpackaging device, which relates to the technical field of cell suspensions and comprises a processing table, a subpackaging mechanism is mounted on one side of the processing table, a mixing mechanism is arranged above the subpackaging mechanism and comprises a supporting frame and a moving plate, one end of the supporting frame is fixedly connected to one side of the processing table, and the other end of the supporting frame is fixedly connected to the other side of the processing table. A first motor works to drive a connecting shaft and a rotating disc to rotate, a second pushing rod does circular motion, a movable plate is driven to obliquely move, and the second pushing rod moves along with the second pushing rod, so that a placing box rotates by taking the positioning rod as a fixed point, suspension in the positioning rod is shaken in a small range, and the suspension is placed in the placing box. And meanwhile, excessive bubbles are prevented from being generated, and the cells are prevented from being damaged.
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Description

Technical Field

[0001] This utility model relates to the field of cell suspension technology, and in particular to a cell suspension dispensing device. Background Technology

[0002] Cell suspension refers to a state in which cells are evenly distributed and suspended in a liquid culture medium. Cells in this state can freely carry out various physiological activities. When using cell suspension, a suspension dispensing device is required to dispense and process it.

[0003] For example, CN216808756U discloses a cell suspension dispensing device, including: a base, a top plate fixedly installed on the top of the base, an installation plate rotatably connected to the bottom of the top plate, a storage tank fixedly installed on the bottom of the installation plate, an infusion mechanism for dispensing cell suspension at the bottom of the storage tank, and an intermittent drive mechanism for driving the installation plate to rotate intermittently at the top of the top plate.

[0004] In the prior art, before cell suspension is dispensed, cells in the cell suspension will precipitate and accumulate after standing, resulting in differences in cell content in different samples dispensed. Uneven cell density will affect the accuracy of experimental results, while excessive shaking will cause air bubbles to be generated inside the suspension, causing cell damage. Utility Model Content

[0005] The purpose of this invention is to solve the problem in the prior art that cells in cell suspensions will precipitate and accumulate after standing, resulting in differences in cell content among different samples, and to propose a cell suspension dispensing device.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: a cell suspension dispensing device, comprising a processing table, a dispensing mechanism installed on one side of the processing table, a mixing mechanism disposed above the dispensing mechanism, the mixing mechanism comprising a support frame and a moving plate, one end of the support frame being fixedly connected to one side of the processing table, a positioning rod being fixedly connected to the inner side of the support frame, one end of the positioning rod being rotatably connected to a placement box, a first pushing rod being fixedly connected to one side of the placement box, a first slot and a second slot being formed on one side of the moving plate, the outer side of the first pushing rod being slidably connected to the inside of the first slot, the inside of the second slot being slidably connected to a second pushing rod, one end of the second pushing rod being fixedly connected to a rotating disk, one end of the moving plate being rotatably connected to a connecting rod, and one end of the connecting rod being fixedly connected to one side of the support frame.

[0007] Preferably, a connecting shaft is fixedly connected to the middle of the rotating disk, one end of the connecting shaft passes through one side of the support frame, a first motor is fixedly connected to one side of the support frame, and a belt assembly is installed between the output end of the first motor and the connecting shaft.

[0008] Preferably, a dispensing tube is fixedly connected to one side of the placement box, and dispensing heads are fixedly connected to both ends of the dispensing tube.

[0009] Preferably, the disassembly mechanism includes a disassembly frame, one end of which passes through one side of the processing table and is fixedly connected to a first gear, one side of which is meshed with a second gear, the middle of which is fixedly connected to a second motor, and one side of which is fixedly connected to one side of the processing table.

[0010] Preferably, a fixing frame is fixedly connected to the inner side of the support frame, and a fixing plate is fixedly connected inside the fixing frame. One side of the fixing plate is fixedly connected to the dispensing head.

[0011] Preferably, a connecting cylinder is fixedly connected to one side of the fixed frame, a movable sleeve is sleeved on one end of the connecting cylinder, and one end of the movable sleeve abuts against one side of the dispensing frame.

[0012] Preferably, a spring is fitted onto the outside of the movable sleeve, with the two ends of the spring abutting against one end of the movable sleeve and one side of the fixed frame, respectively.

[0013] Compared with the prior art, the advantages and positive effects of this utility model are as follows:

[0014] 1. In this utility model, the first motor drives the connecting shaft and the rotating disk to rotate, and the second push rod makes a circular motion, which drives the moving plate to tilt. The second push rod moves accordingly, so that the placement box rotates around the positioning rod as a fixed point, and the suspension inside the positioning rod is shaken slightly to ensure that the cell suspension is mixed evenly, while avoiding the generation of too many bubbles that could damage the cells.

[0015] 2. In this utility model, the second motor drives the second gear to rotate, and the dispensing rack rotates accordingly, switching dispensing bottles for dispensing. During the switching process, the spring force pushes the moving sleeve to maintain contact with the top side of the dispensing rack, reducing the contact between one end of the dispensing head and the air, reducing the possibility of external microorganisms, dust and other pollutants entering the dispensing head and the suspension, thereby ensuring the purity and quality of the cell suspension. Attached Figure Description

[0016] Figure 1 This invention provides a three-dimensional structural schematic diagram of a cell suspension dispensing device;

[0017] Figure 2This utility model provides a schematic diagram of the connection structure of the mixing mechanism of a cell suspension dispensing device;

[0018] Figure 3 This invention provides a schematic diagram of the rotating disk connection structure of a cell suspension dispensing device;

[0019] Figure 4 This invention provides a disassembly diagram of the dispensing mechanism of a cell suspension dispensing device.

[0020] Legend: 1. Processing table; 2. Mixing mechanism; 21. Support frame; 22. First motor; 23. Placement box; 24. Positioning rod; 25. Dispensing tube; 26. Dispensing head; 27. Rotary disk; 28. Belt assembly; 29. ​​Connecting shaft; 210. First slot; 211. Second slot; 212. First push rod; 213. Second push rod; 214. Moving plate; 215. Connecting rod; 3. Dispensing mechanism; 31. Dispensing frame; 32. Moving sleeve; 33. Spring; 34. Fixed frame; 35. Fixed plate; 36. First gear; 37. Second motor; 38. Second gear; 39. Connecting cylinder. Detailed Implementation

[0021] To better understand the above-mentioned objectives, features, and advantages of this utility model, the present utility model will be further described below with reference to the accompanying drawings and embodiments. It should be noted that, unless otherwise specified, the embodiments and features described in these embodiments can be combined with each other.

[0022] Many specific details are set forth in the following description in order to provide a full understanding of the present invention. However, the present invention may also be implemented in other ways different from those described herein. Therefore, the present invention is not limited to the specific embodiments disclosed in the following specification.

[0023] Example 1: As Figure 1 - Figure 4As shown, this utility model provides a cell suspension dispensing device, including a processing table 1. A dispensing mechanism 3 is installed on one side of the processing table 1, and a mixing mechanism 2 is arranged above the dispensing mechanism 3. The mixing mechanism 2 includes a support frame 21 and a moving plate 214. One end of the support frame 21 is fixedly connected to one side of the processing table 1, and a positioning rod 24 is fixedly connected to the inner side of the support frame 21. One end of the positioning rod 24 is rotatably connected to a placement box 23. A first pushing rod 212 is fixedly connected to one side of the placement box 23. A first slot 210 and a second slot 211 are opened on one side of the moving plate 214. The first pushing rod 212... The external sliding connection of 12 is inside the first slot 210, and the internal sliding connection of the second slot 211 is a second push rod 213. One end of the second push rod 213 is fixedly connected to a rotating disk 27, and one end of the moving plate 214 is rotatably connected to a connecting rod 215. One end of the connecting rod 215 is fixedly connected to one side of the support frame 21. A connecting shaft 29 is fixedly connected to the middle of the rotating disk 27. One end of the connecting shaft 29 passes through one side of the support frame 21. A first motor 22 is fixedly connected to one side of the support frame 21. A belt assembly 28 is installed between the output end of the first motor 22 and the connecting shaft 29.

[0024] The belt assembly 28 consists of two pulleys and a conveyor belt. Before dispensing, the first motor 22 drives the connecting shaft 29 and the rotating disk 27 to rotate. A second push rod 213 is eccentrically arranged on one side of the rotating disk 27. During the circular motion of the second push rod 213, it slides inside the second slot 211, causing the moving plate 214 to tilt about the connecting rod 215 as a fixed point. The first slot 210 tilts accordingly, thereby causing the second push rod 213 sliding inside it to move. This causes the placement box 23 to rotate about the positioning rod 24 as a fixed point, and the suspension inside the positioning rod 24 to be shaken slightly to ensure that the cell suspension is mixed evenly and to avoid generating too many bubbles that could damage the cells.

[0025] Example 2: Figure 1 and Figure 4As shown, a dispensing tube 25 is fixedly connected to one side of the placement box 23, and dispensing heads 26 are fixedly connected to both ends of the dispensing tube 25; the dispensing mechanism 3 includes a dispensing frame 31, one end of the dispensing frame 31 passes through one side of the processing table 1 and is fixedly connected to a first gear 36, one side of the first gear 36 is meshed with a second gear 38, the middle of the second gear 38 is fixedly connected to a second motor 37, and one side of the second motor 37 is fixedly connected to one side of the processing table 1; a fixed frame 34 is fixedly connected to the inner side of the support frame 21, a fixed plate 35 is fixedly connected to the inside of the fixed frame 34, and one side of the fixed plate 35 is fixedly connected to the dispensing head 26; a connecting cylinder 39 is fixedly connected to one side of the fixed frame 34, a movable sleeve 32 is sleeved on one end of the connecting cylinder 39, and one end of the movable sleeve 32 abuts against one side of the dispensing frame 31; a spring 33 is sleeved on the outside of the movable sleeve 32, and the two ends of the spring 33 abut against one end of the movable sleeve 32 and one side of the fixed frame 34, respectively.

[0026] The dispensing bottles are placed in the openings on the dispensing rack 31. During dispensing, the second motor 37 drives the second gear 38 to rotate. The second gear 38 meshes with the first gear 36, thereby driving the dispensing rack 31 to rotate. This causes the bottle mouths of different dispensing bottles on the dispensing rack 31 to contact the moving sleeve 32. The suspension inside the placement box 23 enters the dispensing bottle through the dispensing tube 25 and the dispensing head 26 for dispensing. When rotating the dispensing rack 31 to switch dispensing bottles, the elastic force of the spring 33 pushes the moving sleeve 32 to maintain contact with the top side of the dispensing rack 31, reducing the contact between one end of the dispensing head 26 and the air. While dispensing quickly, this reduces the possibility of external microorganisms, dust, and other contaminants entering the dispensing head 26 and the suspension, thereby ensuring the purity and quality of the cell suspension.

[0027] The usage and working principle of this device are as follows: Before dispensing, the first motor 22 operates, driving the connecting shaft 29 and the rotating disk 27 to rotate. The second push rod 213 makes a circular motion and slides inside the second slot 211, causing the moving plate 214 to tilt around the connecting rod 215 as a fixed point. The first slot 210 tilts accordingly, thereby driving the second push rod 213, which slides inside, to move. This causes the placement box 23 to rotate around the positioning rod 24 as a fixed point, mixing the suspension inside the positioning rod 24 evenly. The dispensing bottle is then placed on the dispensing rack 31, with the bottle mouth contacting the moving sleeve 32. The suspension inside the placement box 23 enters the dispensing bottle for dispensing. The second motor 37 operates, driving the second gear 38 to rotate, causing the dispensing rack 31 to rotate accordingly, switching dispensing bottles for dispensing. At the same time, the spring 33 pushes the moving sleeve 32 to maintain contact with the top side of the dispensing rack 31, reducing contact with air during dispensing.

[0028] The above description is merely a preferred embodiment of the present utility model and is not intended to limit the present utility model in any other way. Any person skilled in the art may make changes or modifications to the above-disclosed technical content to create equivalent embodiments for application in other fields. However, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present utility model without departing from the technical solution of the present utility model shall still fall within the protection scope of the technical solution of the present utility model.

Claims

1. A cell suspension dispensing device, comprising a processing table (1), characterized in that: A dispensing mechanism (3) is installed on one side of the processing table (1), and a mixing mechanism (2) is provided above the dispensing mechanism (3). The mixing mechanism (2) includes a support frame (21) and a moving plate (214). One end of the support frame (21) is fixedly connected to one side of the processing table (1), and a positioning rod (24) is fixedly connected to the inner side of the support frame (21). One end of the positioning rod (24) is rotatably connected to a placement box (23), and a first push rod (212) is fixedly connected to one side of the placement box (23). The movable plate (214) has a first slot (210) and a second slot (211) on one side. The first push rod (212) is slidably connected to the outside of the first slot (210). The second push rod (213) is slidably connected to the inside of the second slot (211). One end of the second push rod (213) is fixedly connected to a rotating disk (27). One end of the movable plate (214) is rotatably connected to a connecting rod (215). One end of the connecting rod (215) is fixedly connected to one side of the support frame (21).

2. The cell suspension dispensing device according to claim 1, characterized in that: A connecting shaft (29) is fixedly connected to the middle of the rotating disk (27). One end of the connecting shaft (29) passes through one side of the support frame (21). A first motor (22) is fixedly connected to one side of the support frame (21). A belt assembly (28) is installed between the output end of the first motor (22) and the connecting shaft (29).

3. The cell suspension dispensing device according to claim 1, characterized in that: The placement box (23) is fixedly connected to a dispensing tube (25) on one side, and dispensing heads (26) are fixedly connected to both ends of the dispensing tube (25).

4. The cell suspension dispensing device according to claim 1, characterized in that: The disassembly mechanism (3) includes a disassembly frame (31). One end of the disassembly frame (31) passes through one side of the processing table (1) and is fixedly connected to a first gear (36). One side of the first gear (36) is meshed with a second gear (38). The middle part of the second gear (38) is fixedly connected to a second motor (37). One side of the second motor (37) is fixedly connected to one side of the processing table (1).

5. The cell suspension dispensing device according to claim 1, characterized in that: A fixing frame (34) is fixedly connected to the inner side of the support frame (21), and a fixing plate (35) is fixedly connected inside the fixing frame (34). One side of the fixing plate (35) is fixedly connected to the dispensing head (26).

6. The cell suspension dispensing device according to claim 5, characterized in that: A connecting tube (39) is fixedly connected to one side of the fixed frame (34), and a movable sleeve (32) is sleeved on one end of the connecting tube (39). One end of the movable sleeve (32) abuts against one side of the dispensing frame (31).

7. A cell suspension dispensing device according to claim 6, characterized in that: A spring (33) is sleeved on the outside of the movable sleeve (32), and the two ends of the spring (33) abut against one end of the movable sleeve (32) and one side of the fixed frame (34), respectively.

Citation Information

Patent Citations

  • Cell suspension subpackaging device

    CN216808756U