Autoimmune antibody testing device

Abstract

The utility model discloses an autoimmune antibody inspection device, which comprises a base and a digital display control panel, a turntable is rotatably arranged above the base, a plurality of uniformly distributed intubation sleeves are arranged on the outer side of the turntable along the circumferential direction, and each intubation sleeve is movably provided with a position adjusting support structure along the axial direction of the intubation sleeve; the base is provided with a rotary oscillation assembly used for conducting rotary driving and up-down offset vibration on the rotary disc, the rotary disc, the insertion pipe sleeve, the rotary oscillation assembly and the like cooperate and cooperate with one another, so that samples placed in the insertion pipe sleeve can be subjected to acting force in different directions, mixing and reaction of the samples are promoted, and the accuracy of the samples is improved. And the accuracy of test results is improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to the field of immune antibody inspection technology, specifically relates to a kind of autoimmune antibody inspection device. BACKGROUND

[0002] Autoimmune antibody detection is used for diagnosing autoimmune disease, and autoantibodies will appear in the serum of most autoimmune disease patients, which can be used to assess the severity of the disease, monitor the remission, flare and recurrence of the disease, and monitor the efficacy.

[0003] The autoimmune antibody detection device with publication number CN215139277U includes a base, a vibration box installed at the middle position above the base, a vibration block installed inside the vibration box, a fan-shaped wheel hinged to the front and rear sides of the vibration block, a No. 1 spring fixedly installed at the four end corners of the outer surface of the vibration block, and guide columns fixedly installed at the four end corners of the outer surface of the vibration box.

[0004] The autoimmune antibody detection device with publication number CN220690945U includes a U-shaped seat and a mounting box, a uniform shaking mechanism fixedly installed at the right end rear of the U-shaped seat, the left part of the uniform shaking mechanism extending into the U-shaped seat, the uniform shaking mechanism fixedly connected between the mounting box, a protective cover provided at the upper end of the mounting box, a controller provided at the right end of the U-shaped seat, and a fixing mechanism movably installed at the front and rear ends of the mounting box.

[0005] However, the current autoimmune antibody detection device has a single shaking mode and direction, and the mixing and reaction of the sample are not good. SUMMARY

[0006] The purpose of the utility model is to provide an autoimmune antibody detection device to solve the above problems.

[0007] To achieve the above purpose, the utility model provides the following technical scheme:

[0008] The utility model provides an autoimmune antibody detection device, which includes a base and a digital control panel, a turntable is rotatably arranged above the base, a plurality of insertion tube sleeves are uniformly distributed on the outer side of the turntable along the circumferential direction thereof, and each insertion tube sleeve is movably provided with a positioning support structure along the axial direction thereof.

[0009] A rotary vibration assembly is arranged on the base to drive the rotation of the turntable and the up-down offset vibration.

[0010] Further, the axial direction of the insertion tube sleeve is inclined to the rotation axis of the turntable, and the distance between the insertion tube sleeve and the rotation axis of the turntable gradually increases from near to far along the direction from top to bottom.

[0011] Further, the position adjusting support structure comprises a support base plate and an outer sleeve ring which are respectively slidably arranged in the cannula sleeve and outside the cannula sleeve, an opening groove is formed on the outer side of the cannula sleeve, the support base plate and the outer sleeve ring are connected to each other by a connecting bolt at the position of the opening groove, and a clamping bolt is threadedly connected to the side wall of the outer sleeve ring to realize clamping abutment with the outer wall of the cannula sleeve.

[0012] Further, the rotating and oscillating assembly comprises an eccentric driving mechanism, a second motor is fixedly arranged at the center position of the rotating disc, the output shaft end of the second motor is downwardly fixedly connected with a lifting guide rod, the lower end of the lifting guide rod extends into the shell in the up-down direction and is driven to move up and down by the eccentric driving mechanism.

[0013] Further, the eccentric driving mechanism comprises a first motor which is fixedly arranged on the inner side wall of the mounting chamber, the output shaft end of the first motor is fixedly connected with an eccentric wheel, the lower end of the lifting guide rod is fixedly arranged with a lower abutting block, the lower side of the lower abutting block is rotatably arranged with an abutting wheel for abutting and rolling with the eccentric wheel, and the outer side of the lifting guide rod between the lower abutting block and the top side of the shell is sleeved with a spring.

[0014] Further, the two sides of the lifting guide rod are provided with two guide rods which are symmetrically distributed with the lifting guide rod as the center, the upper ends of the two guide rods are fixedly arranged on the top side of the mounting chamber, and the lower ends of the guide rods are slidably connected into the guide sliding holes which are formed in the corresponding positions of the lower abutting block.

[0015] Further, one side of the upper part of the base is provided with a side baffle, and the bottom side of the base is fixedly arranged with a plurality of supporting legs along the edge thereof.

[0016] Compared with the prior art, the utility model has the advantages that:

[0017] 1. Through the mutual cooperation and mutual cooperation between the rotating disc, the cannula sleeve and the rotating and oscillating assembly, the sample placed in the cannula sleeve is subjected to different directional forces, the mixing and reaction of the sample are promoted, and the accuracy of the test result is improved.

[0018] 2. The axial direction of the cannula sleeve and the rotating shaft of the rotating disc are arranged in an inclined manner, so that the sample can be subjected to different degrees of centrifugal force during rotation, which is more conducive to the mixing and reaction of the sample, and under the action of the centripetal force, the sample test tube can be firmly fixed in the cannula sleeve.

[0019] 3. The position adjusting support structure can adjust the position along the axial direction of the cannula sleeve, so as to realize the adjustment of the sample position and adapt to the insertion of sample test tubes of different lengths and sizes.

[0020] In order to more clearly illustrate the technical scheme in the embodiments of the present application or the prior art, the following will briefly introduce the drawings needed to be used in the embodiment or prior art description, obviously, the drawings in the following description are only some embodiments of the present application, and for those skilled in the art, other drawings can also be obtained without creative labor on the basis of these drawings. BRIEF DESCRIPTION OF DRAWINGS

[0021] Figure 1 is a front view structural schematic diagram of the present application;

[0022] Figure 2 is a right view structural schematic diagram of the present application Figure 1 ;

[0023] Figure 3 is a perspective view structural schematic diagram of the present application Figure 1 ;

[0024] Figure 4 is a C place local amplification structural schematic diagram of the present application Figure 3 ;

[0025] Figure 5 is an A-A section structural schematic diagram of the present application Figure 1 ;

[0026] Figure 6 is a B-B section structural schematic diagram of the present application Figure 2 .

[0027] The following is explained: 1, base; 101, side baffle; 102, supporting leg; 2, rotary disc; 3, cannula sleeve; 301, opening groove; 4, position adjusting support structure; 401, inner support seat plate; 402, outer sleeve ring; 403, connecting bolt; 404, locking bolt; 5, rotary oscillation assembly; 501, shell; 502, first motor; 503, eccentric wheel; 504, lower abutting block; 505, abutting wheel; 506, lifting guide rod; 507, spring; 508, bottom cover; 509, second motor; 510, guide rod; 511, mounting chamber; 6, digital display control panel. DETAILED DESCRIPTION

[0028] In order to make the purpose, technical scheme and advantages of the present application more clear, the technical scheme of the present application will be described in detail below. Obviously, the described embodiments are only some embodiments of the present application, not all embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor belong to the scope of protection of the present application.

[0029] Referring toFigures 1-6 The utility model provides a kind of autoimmune antibody testing device, including base 1 and digital display control panel 6, the upper portion side of base 1 is provided with side baffle 101, wherein, side baffle selects transparent high-strength acrylic plate, the bottom side of base 1 is fixedly provided with several supporting legs 102 along its brim.102 adopts rubber and metal composite material, metal part is firmly connected with base, and rubber part contacts ground.Rubber material has good shock absorption and antiskid performance, effectively reduce the vibration generated when equipment operates to ground, while avoiding displacement of equipment during working process.

[0030] As shown in the description Figure 1 , Figure 2 and Figure 3 As shown in the description, rotary disc 2 is rotationally arranged above base 1, and a plurality of insertion tube sleeves 3 are uniformly distributed along the circumferential direction of the outer side of rotary disc 2. Each insertion tube sleeve 3 is movably arranged with a positioning support structure 4 along its axial direction. A rotary oscillation assembly 5 is arranged on base 1 for driving the rotation and up-down offset vibration of rotary disc 2. The axial direction of insertion tube sleeve 3 is inclined to the rotation axis of rotary disc 2, and the distance from the rotation axis of rotary disc 2 in the direction from top to bottom of insertion tube sleeve 3 gradually increases. In actual application, the axial direction of insertion tube sleeve 3 is inclined to the rotation axis of rotary disc 2 at an angle of 15°-30°, which can make the sample receive different degrees of centrifugal force during rotation, which is more conducive to the mixing and reaction of the sample. Under the action of centripetal force, the sample tube can also be firmly fixed in the insertion tube sleeve 3.

[0031] As shown in the description Figure 3 , Figure 4 and As shown in the description, positioning support structure 4 includes a support seat plate 401 slidably arranged in insertion tube sleeve 3 and an outer sleeve ring 402 slidably arranged outside insertion tube sleeve 3. An opening groove 301 is formed in the outer side of insertion tube sleeve 3. The support seat plate 401 and the outer sleeve ring 402 are connected to each other by a connecting bolt 403 at the position of the opening groove 301. A clamping bolt 404 is threadedly connected to the side wall of the outer sleeve ring 402 for clamping and abutting against the outer wall of the insertion tube sleeve 3. In actual application, the outer sleeve ring 402 is made of high-strength engineering plastic, which has good wear resistance and corrosion resistance. The inner diameter of the outer sleeve ring 402 is matched with the outer diameter of the insertion tube sleeve 3, and the outer sleeve ring 402 can slide freely outside the sleeve.

[0032] Figure 3 , Figure 5 and Figure 6As shown, the rotating and oscillating assembly 5 comprises an eccentric driving mechanism, a second motor 509 is fixedly arranged at the center position of the rotating disc 2, the output shaft end of the second motor 509 faces downward and is fixedly connected with a lifting guide rod 506, the lower end of the lifting guide rod 506 extends into the shell 501 in the up-down direction and is driven to move up and down by the eccentric driving mechanism. The eccentric driving mechanism comprises a first motor 502 fixedly arranged on the inner side wall of the mounting chamber 511, the output shaft end of the first motor 502 is fixedly connected with an eccentric wheel 503, the lower end of the lifting guide rod 506 is fixedly arranged with a lower abutting block 504, the lower side of the lower abutting block 504 is rotatably provided with an abutting wheel 505 for abutting and rolling with the eccentric wheel 503, the outer side of the lifting guide rod 506 between the lower abutting block 504 and the top side of the shell 501 is sleeved with a spring 507. The two sides of the lifting guide rod 506 are provided with two guide rods 510 symmetrically distributed with the lifting guide rod 506 as the center, the upper ends of the two guide rods 510 are fixedly arranged on the top side of the mounting chamber 511, and the lower ends of the guide rods 510 are slidingly connected into the guide sliding hole provided in the corresponding position of the lower abutting block 504. In actual application, the bottom side of the mounting chamber 511 is open and the opening is provided with a bottom cover 508 through bolts.

[0033] Working principle:

[0034] When it is necessary to adjust the position of the sample in the insertion tube sleeve 3, the operator first loosens the clamping bolt 404, releases the clamping state of the outer sleeve ring 402 and the outer wall of the insertion tube sleeve 3, at this time, the outer sleeve ring 402 can be manually moved to drive the inner support seat plate 401 connected thereto to slide up and down in the insertion tube sleeve 3. The sample container placed thereon can move with the movement of the inner support seat plate 401, so as to realize the adjustment of the sample position. After adjustment to the appropriate position, the clamping bolt 404 is tightened to clamp the outer sleeve ring 402 and the outer wall of the insertion tube sleeve 3, and the fixing of the sample position is completed.

[0035] When the operator starts the second motor 509 through the digital display control panel 6, the output shaft of the second motor drives the rotating disc 2 connected thereto to rotate around the central axis relative to the lifting guide rod 506. The rotation of the rotating disc 2 causes the insertion tube sleeve 3 distributed in the circumferential direction of the rotating disc 2 to rotate, and the samples placed in the insertion tube sleeves 3 at different positions also make circumferential motion.

[0036] After the first motor 502 is started, the first motor 502 output shaft drives eccentric wheel 503 to rotate at high speed. In the process of rotation, due to the eccentric structure of the eccentric wheel 503, it will generate periodic force to the contact wheel 505. The contact wheel 505 is installed on the lower surface of the lower block 504, which converts the circular motion of the eccentric wheel 503 into the up-down motion of the lower block 504. The lower block 504 is fixedly connected with the lifting guide rod 506, so the lifting guide rod 506 also moves up and down with the lower block. On both sides of the lifting guide rod 506, the guide rods 510 symmetrically distributed play a guiding role, ensuring that the lifting guide rod 506 maintains linear motion during the up-down motion and does not deviate. At the same time, the spring 507 sleeved on the outer side of the lifting guide rod 506 plays a buffering and resetting role when the lifting guide rod 506 moves up and down, making the movement of the lifting guide rod 506 more stable. The up-down motion of the lifting guide rod 506 is transmitted to the turntable 2 through the connection with the second motor 509 output shaft, so that the turntable 2 can rotate and also offset and vibrate up and down. This rotary oscillation movement can make the sample placed in the cannula sleeve receive different direction forces, promote the mixing and reaction of the sample, and improve the accuracy of the test results.

[0037] The above is only a specific embodiment of the present application, but the protection scope of the present application is not limited to this. Any skilled person in the art can easily think of changes or replacements within the technical range disclosed by the present application, which should be covered within the protection scope of the present application. Therefore, the protection scope of the present application should be subject to the protection scope of the claims.

Claims

1. An autoimmune antibody test device, characterized by: Including base (1) and digital display control panel (6), the base (1) is rotationally arranged with rotary table (2) above, the outer side of rotary table (2) is uniformly distributed with several insertion tube sleeves (3) along its circumferential direction, each insertion tube sleeve (3) is movably arranged with position adjusting support structure (4) along its axial direction; Rotary oscillation assembly (5) is arranged on the base (1) for driving rotary table (2) to rotate and offset vibration up and down.

2. The autoimmune antibody test device of claim 1, wherein: The axial direction of the insertion tube sleeve (3) is inclined to the rotation axis of the rotary table (2), and the insertion tube sleeve (3) is arranged from near to far along the direction from top to bottom.

3. The autoimmune antibody test device according to claim 1 or 2, characterized in that: The position adjusting support structure (4) includes a support seat plate (401) slidingly arranged in the insertion tube sleeve (3) and an outer sleeve ring (402) slidingly arranged outside the insertion tube sleeve (3), an opening slot (301) is formed in the outer side of the insertion tube sleeve (3), the support seat plate (401) and the outer sleeve ring (402) are connected to each other by a connecting bolt (403) at the position of the opening slot (301), and the side wall of the outer sleeve ring (402) is threadedly connected with a clamping bolt (404) for realizing clamping abutment with the outer wall of the insertion tube sleeve (3).

4. The device for testing of autoimmune antibodies according to claim 1, characterized in that: The rotary oscillation assembly (5) includes an eccentric drive mechanism, a second motor (509) is fixedly arranged at the center position of the rotary table (2), the output shaft end of the second motor (509) faces downward and is fixedly connected with a lifting guide rod (506), the lower end of the lifting guide rod (506) extends into the outer shell (501) along the up-down direction and is driven to move up and down by the eccentric drive mechanism.

5. The device for testing of autoantibodies according to claim 4, characterized in that: The eccentric drive mechanism includes a first motor (502) fixedly arranged on the inner side wall of the mounting chamber (511), the output shaft end of the first motor (502) is fixedly connected with an eccentric wheel (503), the lower end of the lifting guide rod (506) is fixedly arranged with a lower abutting block (504), the lower side of the lower abutting block (504) is rotationally arranged with an abutting wheel (505) for abutting and rolling with the eccentric wheel (503), and the outer side of the lifting guide rod (506) between the lower abutting block (504) and the top side of the outer shell (501) is sleeved with a spring (507).

6. The device for testing of autoantibodies according to claim 5, characterized in that: Two guide rods (510) are symmetrically distributed around the lifting guide rod (506), the upper ends of the two guide rods (510) are fixedly arranged on the top side of the mounting chamber (511), and the lower ends of the guide rods (510) are slidingly connected into the guide sliding hole of the corresponding position of the lower abutting block (504).

7. The device of claim 1, wherein: One side of the upper part of the base (1) is provided with a side baffle (101), and the bottom side of the base (1) is fixedly provided with a plurality of supporting legs (102) along the edge.

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