Purification equipment for preparing chitosan oligosaccharide medicine

Abstract

The utility model discloses a purification device for chitosan oligosaccharide drug preparation, which comprises a tank body, the bottom of the tank body is fixedly communicated with a conical discharge pipe, the outer wall of the tank body is fixedly communicated with a feed pipe, the top of the tank body is inserted with a movable rod, and the bottom end of the movable rod penetrates through the tank body and is fixedly connected with a mounting block. Scraping assemblies attached to the inner wall of the tank body all the time are connected to the four side walls of the mounting block correspondingly, and the movable rods, the mounting block, the scraping assemblies, the fixing shell, the first driving motor, the mounting frame and the power assembly are arranged and used in cooperation, so that the scraping assemblies can be driven by the first driving motor to rotate; the scraping assembly can be moved from top to bottom along the axial direction of the tank body through the power assembly, so that attachments on the inner wall of the tank body can be comprehensively scraped, the influence of residues on a subsequent purification process is avoided, and the cleanliness and the purification effect of the purification equipment are ensured; meanwhile, material waste is avoided.

Description

TECHNICAL FIELD

[0001] The utility model relates to chitosan oligosaccharide processing technical field, concretely is a kind of purification equipment for chitosan oligosaccharide drug preparation. BACKGROUND

[0002] Chitosan oligosaccharide, also known as chitosan oligosaccharide and oligochitosan, is a kind of oligosaccharide product with a degree of polymerization of 2-20, which is obtained by special biological enzyme technology (also reported using chemical degradation, microwave degradation technology). It is a low molecular weight product with good water solubility, large functional effect and high biological activity. The separation and purification of chitosan oligosaccharide requires a series of separation and purification steps, such as ultrafiltration, ion exchange chromatography and gel filtration, to remove impurities and purify chitosan oligosaccharide product.

[0003] For example, a chitosan oligosaccharide separation and purification device (publication number: CN221015394U), the device includes a bottom plate, the bottom plate bottom end four corners are fixedly connected with base, the bottom plate upper end right part is fixedly connected with support rod, the bottom plate upper end left part is fixedly connected with coagulation device, the support rod upper end is fixedly connected with filter device, the filter device upper end left part and upper end right part are fixedly connected with feed inlet, the filter device left part lower side is fixedly connected with discharge port, the utility model discloses a kind of chitosan oligosaccharide separation and purification device, cooperate the use of semi-permeable membrane to separate chitosan oligosaccharide and sodium chloride in chitosan oligosaccharide, and chitosan oligosaccharide solution is distilled crystallization by heating, cooperate the use of L-shaped scraper, in the process of distillation, chitosan oligosaccharide crystals on the inner wall of distillation device are scraped out while stirring, improve distillation efficiency, and also can completely collect chitosan oligosaccharide crystals, improve collection amount, save cost.

[0004] The above device can scrape out chitosan oligosaccharide crystals on the inner wall of the device, but the inner bottom of the coagulation device is flat, so the scraper may not completely discharge chitosan oligosaccharide crystals inside the device, which may cause material waste, therefore we need to propose a kind of purification equipment for chitosan oligosaccharide drug preparation. UTILITY MODEL CONTENTS

[0005] The utility model aims to provide a kind of purification equipment for chitosan oligosaccharide drug preparation, to solve the problems raised in the above background technology.

[0006] To achieve the above purpose, the utility model provides the following technical scheme:

[0007] The application discloses a kind of chitosan oligosaccharide medicine preparation's purification equipment, including jar body, the bottom of the jar body is fixedly connected with conical discharge pipe, the outer wall of the jar body is fixedly connected with feed pipe, the top of the jar body is inserted with movable rod, the bottom end of the movable rod penetrates jar body and is fixedly connected with mounting block, the four side walls of the mounting block are respectively connected with scraping assembly that is always attached to jar body inner wall, the top end of the movable rod is rotatably connected with fixed shell, and the top end of the movable rod penetrates fixed shell and is connected with first driving motor, the top of the jar body is fixedly connected with mounting bracket, and the mounting bracket is provided with power component for lifting adjustment of fixed shell.

[0008] Preferably, the scraping assembly includes a fixed sleeve fixedly installed on the side wall of the mounting block, a slide rod is slidably inserted into the inside of the fixed sleeve, one end of the slide rod is fixedly connected with a positioning plate, and one side wall of the positioning plate is fixedly connected with a deformable scraper.

[0009] Preferably, a spring is further included, one end of the spring is fixedly connected to one end of the slide rod, and the other end of the spring is fixedly connected to one side inner wall of the fixed sleeve.

[0010] Preferably, the power component includes a lead screw, the top end and the bottom end of the lead screw are rotatably installed at the inner top and the inner bottom of the mounting bracket respectively, the top end of the lead screw penetrates the mounting bracket and is connected with a second driving motor, the outer wall of the lead screw is threadedly connected with a movable block, and one side of the movable block is fixedly connected with one side of the fixed shell.

[0011] Preferably, a limiting slide block is fixedly connected to one side wall of the movable block, a limiting groove that is matched with the limiting slide block is formed in one side wall of the mounting bracket, and the limiting slide block is slidably connected to the inside of the limiting groove.

[0012] Preferably, the second driving motor is fixedly installed at the top of the mounting bracket, and one end of the output shaft of the second driving motor is fixedly connected with the top end of the lead screw.

[0013] Preferably, a sliding sleeve is fixedly embedded at the top of the jar body, and the movable rod is slidably inserted into the inside of the sliding sleeve.

[0014] Compared with the prior art, the application has the following beneficial effects:

[0015] The utility model discloses a movable rod, mounting block, scraping assembly, fixed shell, first drive motor, mounting frame and the cooperation of power assembly can be scraped by the first drive motor and drive scraping assembly to rotate, and the chitosan attached to the inner wall of the jar can be scraped, and the scraping assembly can be moved from top to bottom along the axial direction of the jar by the power assembly, so that the attachments on the inner wall of the jar can be scraped comprehensively, the subsequent purification process is prevented from being affected by the residual, the cleanliness and purification effect of the purification equipment are ensured, the product quality is improved, and material waste is avoided. BRIEF DESCRIPTION OF DRAWINGS

[0016] Figure 1 It is the structural diagram of the utility model;

[0017] Figure 2 It is the structural diagram of the utility model jar inside;

[0018] Figure 3 It is the structural diagram of the utility model scraping assembly;

[0019] Figure 4 It is the structural diagram of the utility model power assembly.

[0020] In the drawing: 1, jar;2, feed pipe;3, movable rod;4, mounting block;5, scraping assembly;501, fixed sleeve;502, sliding rod;503, positioning plate;504, deformable scraper;505, spring;6, fixed shell;7, first drive motor;8, mounting frame;9, power assembly;901, screw;902, second drive motor;903, movable block;10, limit sliding block;11, limit slot;12, conical discharge pipe;13, sliding sleeve. DETAILED DESCRIPTION

[0021] The technical scheme in the embodiments of the utility model will be described clearly and completely below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of the utility model.

[0022] Please refer to Figures 1-4 The utility model provides a technical scheme:

[0023] The application discloses a kind of chitosan oligosaccharide medicine preparation purification equipment, including jar body 1, the bottom of jar body 1 is fixedly connected with conical discharge pipe 12, the outer wall of jar body 1 is fixedly connected with feed pipe 2, the top of jar body 1 is inserted with movable rod 3, the bottom end of movable rod 3 penetrates jar body 1 and is fixedly connected with mounting block 4, the four side walls of mounting block 4 are respectively connected with scraping assembly 5 that always is attached with the inner wall of jar body 1, the top end of movable rod 3 is rotatably connected with fixed shell 6, and the top end of movable rod 3 penetrates fixed shell 6 and is connected with first drive motor 7, the top of jar body 1 is fixedly connected with mounting bracket 8, mounting bracket 8 is provided with power assembly 9 for lifting adjustment of fixed shell 6, by the cooperation of movable rod 3, mounting block 4, scraping assembly 5, fixed shell 6, first drive motor 7, mounting bracket 8 and power assembly 9, the rotation of scraping assembly 5 can be driven by first drive motor 7, so that the chitosan oligosaccharide attached to the inner wall of jar body 1 can be scraped, and the scraping assembly 5 can be moved from top to bottom along the axial direction of jar body 1 by power assembly 9, so that the attachments on the inner wall of jar body 1 can be completely scraped, avoiding the influence of residues on subsequent purification process, ensuring the cleanliness and purification effect of the purification equipment, improving product quality, and avoiding material waste;

[0024] Scraping assembly 5 includes fixed sleeve 501, which is fixedly installed on the side wall of mounting block 4, a sliding rod 502 is slidably inserted into the inside of fixed sleeve 501, a limiting slide rail is provided on the inner wall of fixed sleeve 501, the sliding rod 502 is slidably connected with the limiting slide rail, one end of the sliding rod 502 is fixedly connected with a positioning plate 503, and a deformable scraper 504 is fixedly connected to one side wall of the positioning plate 503.

[0025] It also includes a spring 505, one end of which is fixedly connected to one end of the sliding rod 502, and the other end of the spring 505 is fixedly connected with one side inner wall of the fixed sleeve 501, when the deformable scraper 504 moves from top to bottom from the jar body 1 to the inside of the conical discharge pipe 12, the deformable scraper 504 can completely adhere to the inner wall of the conical discharge pipe 12 by being provided, in addition, the deformable scraper 504 can be completely attached to the inner wall of the jar body 1 or the conical discharge pipe 12 by the free expansion of the spring 505;

[0026] Power assembly 9 includes a lead screw 901, the top end and the bottom end of the lead screw 901 are rotatably installed at the inner top and the inner bottom of the mounting bracket 8 respectively, and the top end of the lead screw 901 penetrates the mounting bracket 8 and is connected with a second drive motor 902, an active block 903 is threadedly connected to the outer wall of the lead screw 901, one side of the active block 903 is fixedly connected with one side of the fixed shell 6, the output shaft of the second drive motor 902 can drive the lead screw 901 to rotate forward or reversely, so that the active block 903 can be reciprocally moved along the axial direction of the lead screw 901, and the scraping assembly 5 can be moved from top to bottom;

[0027] A limiting slider 10 is fixedly connected to one side wall of the movable block 903. A limiting groove 11 adapted to the limiting slider 10 is provided on one side wall of the mounting bracket 8. The limiting slider 10 is slidably connected to the inside of the limiting groove 11. By setting the limiting slider 10 and the limiting groove 11 to work together, the movable block 903 is limited, making its movement process more stable.

[0028] The second drive motor 902 is fixedly installed on the top of the mounting bracket 8. One end of the output shaft of the second drive motor 902 is fixedly connected to the top end of the lead screw 901. The second drive motor 902 is configured as a forward and reverse stepper motor.

[0029] A sliding sleeve 13 is fixedly installed on the top of the tank body 1. The movable rod 3 is slidably inserted into the inside of the sliding sleeve 13. By setting the sliding sleeve 13, the movable rod 3 can slide along the axial direction of the sliding sleeve 13 and rotate along the radial direction of the sliding sleeve 13.

[0030] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A chitosan oligosaccharide pharmaceutical preparation purification device comprising a tank body (1), characterized in that: The bottom of the tank body (1) is fixedly connected with a conical discharge pipe (12), the outer wall of the tank body (1) is fixedly connected with a feed pipe (2), the top of the tank body (1) is inserted with a movable rod (3), the bottom end of the movable rod (3) penetrates the tank body (1) and is fixedly connected with a mounting block (4), the four side walls of the mounting block (4) are respectively connected with scraping assemblies (5) which are always attached to the inner wall of the tank body (1), the top end of the movable rod (3) is rotatably connected with a fixed shell (6), the top end of the movable rod (3) penetrates the fixed shell (6) and is connected with a first driving motor (7), the top of the tank body (1) is fixedly connected with a mounting rack (8), and the mounting rack (8) is provided with a power assembly (9) for lifting adjustment of the fixed shell (6).

2. The chitooligosaccharide pharmaceutical preparation purification device according to claim 1, characterized in that: The scraping assembly (5) comprises a fixed sleeve (501) fixedly installed on the side wall of the mounting block (4), a sliding rod (502) slidably inserted into the fixed sleeve (501), and a deformable scraper (504) fixedly connected to one side of the side wall of the positioning plate (503).

3. The chitooligosaccharide pharmaceutical preparation purification apparatus according to claim 2, characterized in that: Further comprising a spring (505), one end of the spring (505) is fixedly connected to one end of the sliding rod (502), and the other end of the spring (505) is fixedly connected to the inner wall of the fixed sleeve (501).

4. The chitooligosaccharide pharmaceutical preparation purification apparatus according to claim 1, characterized by: The power assembly (9) comprises a lead screw (901), the top end and the bottom end of the lead screw (901) are rotatably installed at the inner top and the inner bottom of the mounting rack (8), respectively, the top end of the lead screw (901) penetrates the mounting rack (8) and is connected with a second driving motor (902), the outer wall of the lead screw (901) is threadedly connected with a movable block (903), and one side of the movable block (903) is fixedly connected with one side of the fixed shell (6).

5. The chitooligosaccharide pharmaceutical preparation purification apparatus according to claim 4, characterized by: One side of the movable block (903) is fixedly connected with a limiting sliding block (10), and one side of the mounting rack (8) is provided with a limiting groove (11) matched with the limiting sliding block (10), and the limiting sliding block (10) is slidably connected in the limiting groove (11).

6. The chitooligosaccharide pharmaceutical preparation purification apparatus according to claim 5, characterized by: The second driving motor (902) is fixedly installed at the top of the mounting rack (8), and one end of the output shaft of the second driving motor (902) is fixedly connected with the top end of the lead screw (901).

7. The chitooligosaccharide pharmaceutical preparation purification apparatus according to claim 1, characterized by: The top of the tank body (1) is fixedly embedded with a sliding sleeve (13), and the movable rod (3) is slidably inserted into the sliding sleeve (13).

Images