Ether substance low-temperature centrifugal device

By designing a low-temperature centrifugation device for ethers and utilizing inert gas and cooling components to reduce temperature, the risk of ignition of ethers during centrifugation was eliminated, thus improving the safety of peptide production.

CN223931628UActive Publication Date: 2026-02-24SICHUAN JISHENG BIOPHARM CO LTD
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Patent Information

Application Number
CN202520333738.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-02-28
Publication Date
2026-02-24
Estimated Expiration
2035-02-28

AI Technical Summary

Technical Problem

In the peptide production process, the low flash point of ethers poses a risk of ignition during centrifugation, which can lead to safety accidents.

Method used

Design a low-temperature centrifugation device for ethers, which uses inert gas to cool the material during centrifugation and circulates the cooling components to cool it. Combined with a temperature sensor and controller to control the power of the gas pump, the device ensures a continuous supply of inert gas.

Benefits of technology

It effectively reduces the temperature of ether substances during centrifugation, avoids the risk of ignition, and improves safety.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a low-temperature centrifugal device for ethers, which comprises a body with a tank body, a centrifugal pan coaxially arranged in the tank body, an air pipe, a cooling component, an air pump and an air tank, the centrifugal pan and the inner lower part of the tank body form a closed space, a plurality of air holes are uniformly formed in the bottom surface of the centrifugal pan, and the air pipe is communicated with the air pipe. A first exhaust port and a second exhaust port are formed in the upper portion of the tank body, one end of the air pipe is connected with the first exhaust port, the other end of the air pipe is connected with the input end of the air pump, the output end of the air pump is communicated with the closed space, and the cooling assembly is configured to cool the air pipe. Inert gas is stored in the gas tank, the gas tank is connected to the gas pipe in a branched mode, and a valve is arranged on the gas pipe. According to the centrifugal equipment, the ignition condition occurring when the centrifugal equipment centrifuges the ether-containing materials can be effectively reduced.
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Description

Technical Field

[0001] This utility model belongs to the field of polypeptide production and processing technology, and relates to a low-temperature centrifugation device for ether substances. Background Technology

[0002] In the production and processing of peptides, initially, peptides are usually mixed with some ethers and other impurities. Centrifugation equipment is generally used to remove impurities. However, ethers usually have a low flash point. During centrifugation, the friction between ethers and other substances will cause the material to heat up, making the ethers in the centrifuge equipment at risk of ignition, thus leading to safety accidents. Utility Model Content

[0003] The purpose of this invention is to provide a low-temperature centrifugation device for ether-containing materials, which effectively reduces the risk of ignition when centrifuging materials containing ethers.

[0004] The technical solution adopted in this utility model is as follows:

[0005] A low-temperature centrifugation device for ethers includes a main body with a tank, a centrifuge disc coaxially arranged inside the tank, a gas pipe, a cooling assembly, a gas pump, and a gas tank. The centrifuge disc and the lower part of the tank form a sealed space. The bottom surface of the centrifuge disc is evenly provided with a plurality of air holes. The upper part of the tank is provided with a first exhaust port and a second exhaust port. One end of the gas pipe is connected to the first exhaust port, and the other end of the gas pipe is connected to the input end of the gas pump. The output end of the gas pump is connected to the sealed space. The cooling assembly is configured to cool the gas pipe. The gas tank stores inert gas and is branched onto the gas pipe. A valve is provided on the gas pipe.

[0006] Furthermore, the sealed space is evenly divided into six parts around the central axis of the centrifugal disc by a partition, and the three parts that are in a centrally symmetrical position are connected to the first switching valve.

[0007] Furthermore, the first switching valve is an electrically controlled valve.

[0008] Furthermore, it also includes a controller and a temperature sensor, the temperature sensor being adapted to monitor the temperature inside the tank, the temperature sensor being connected to the input terminal of the controller, and the output terminal of the controller being connected to the air pump.

[0009] Furthermore, it also includes a control panel connected to the controller.

[0010] Furthermore, it also includes a suction pump, the input end of which is connected to the tank body, and the output end of which is connected to the outside.

[0011] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0012] This novel low-temperature centrifuge device includes a main body with a tank, as well as a gas pipe, a cooling component, a gas pump, and a gas tank. Before centrifugation, the second exhaust port is opened, and inert gas from the gas tank is introduced into the tank, forcing the air inside the tank out through the second exhaust port. The second exhaust port is then closed, and the material to be centrifuged is placed into the tank of the main body. During centrifugation, the gas pump continuously enters the sealed space and is introduced through the air vent. Inert gas overflows from the side of the material and the ground, which not only reduces the adsorption of different material components but also allows the low-temperature inert gas to carry away heat, preventing the risk of ignition due to excessively high temperatures in ether-containing substances. Simultaneously, the inert gas flowing through the material is discharged through the first exhaust port and cooled by the cooling component before being recycled back into the tank. This effectively reduces the internal temperature of the tank, minimizing the risk of ignition when centrifuging ether-containing materials. Furthermore, the amount of inert gas can be replenished through the gas tank when necessary. Attached Figure Description

[0013] To more clearly illustrate the technical solutions of the embodiments of this utility model, the drawings used in the embodiments will be briefly described below. It should be understood that the following drawings only show some embodiments of this utility model and should not be regarded as a limitation on the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort, wherein:

[0014] Figure 1 This is a schematic diagram of the structure of a low-temperature centrifugation device for ether substances according to an embodiment of the present invention;

[0015] Figure 2 This is a schematic diagram of the centrifuge disc in an embodiment of the present invention;

[0016] Marked in the image:

[0017] 10-Tank body; 11-Centrifuge disc; 111-Air vent; 112-First switch valve; 12-Sealed space; 13-First exhaust port; 14-Second exhaust port;

[0018] 20 - Trachea; 21 - Valve;

[0019] 30 - Cooling components;

[0020] 40 - Air pump;

[0021] 50-Gas Tank. Detailed Implementation

[0022] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only for explaining the present utility model and are not intended to limit the present utility model; that is, the described embodiments are only some embodiments of the present utility model, and not all embodiments. The components of the embodiments of the present utility model described and shown in the accompanying drawings can generally be arranged and designed in various different configurations.

[0023] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

[0024] It should be noted that relational terms such as "first" and "second" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0025] As described in the background section, in the initial production and processing of peptides, peptides are usually mixed with some ethers and other impurities. Centrifugation equipment is generally used to remove impurities. However, ethers usually have a low flash point. During centrifugation, the friction between ethers and other substances will cause the material to heat up, making the ethers in the centrifugation equipment at risk of ignition, which may lead to safety accidents.

[0026] Based on this, the inventors created a low-temperature centrifugation device for ether substances, as described in this application, to solve the aforementioned technical problems.

[0027] The features and performance of this utility model will be further described in detail below with reference to the embodiments.

[0028] Example

[0029] Please see Figure 1 , Figure 2A low-temperature centrifuge device for ether-based substances includes a main body with a tank 10, inside which a centrifuge disc 11 is coaxially arranged. It should be noted that the centrifuge disc 11 refers to a rotating component that primarily centrifuges the material; for example, the edge of the centrifuge disc 11 can be fitted into the side wall of the tank 10. The low-temperature centrifuge device also includes a gas pipe 20, a cooling assembly 30, a gas pump 40, and a gas tank 50. The centrifuge disc 11 and the lower inner part of the tank 10 form a sealed space 12. Here, inert gas is introduced into the sealed space, allowing it to exit through the gas vent 111, thus flowing from the bottom surface towards the material, dispersing the material while simultaneously cooling it. The bottom surface of the centrifugal disc 11 is evenly provided with a plurality of air holes 111. The upper part of the tank 10 is provided with a first exhaust port 13 and a second exhaust port 14. One end of the air pipe 20 is connected to the first exhaust port 13, and the other end of the air pipe 20 is connected to the input end of the air pump 40. The output end of the air pump 40 is connected to the sealed space 12. The cooling component 30 is configured to cool the air pipe 20. The gas tank 50 stores inert gas and branches off to the air pipe 20. A valve 21 is provided on the air pipe 20. Here, the first exhaust port 13 is mainly used for the circulation of inert gas, and the second exhaust port 14 is mainly used to discharge air during initial use, so that the tank 10 is filled with inert gas. For example, the cooling component 30 can be a water-cooling device, which achieves cooling by wrapping the water-cooling device around the air pipe 20, or it can be a refrigerator, etc. This utility model is not limited to these.

[0030] The low-temperature centrifuge device of this invention includes a main body with a tank 10, a gas pipe 20, a cooling component 30, a gas pump 40, and a gas tank 50. Before centrifugation, the second exhaust port 14 is opened, and inert gas from the gas tank 50 is introduced into the tank 10, squeezing out the air inside the tank 10 from the second exhaust port 14. The second exhaust port 14 is then closed, and the material to be centrifuged is placed into the tank 10 of the main body. During centrifugation, the gas pump 40 continuously enters the sealed space 12 and is introduced through the air hole 111. Inert gas overflows from the side of the material and the ground, which not only reduces the adsorption of different material components, but also allows the low-temperature inert gas to carry away heat, preventing the risk of ignition due to excessively high temperatures in ether-containing substances. At the same time, the inert gas flowing through the material is discharged through the first exhaust port 13 and cooled by the cooling component 30 before being recycled back into the tank 10. This effectively reduces the temperature inside the tank 10, reducing the risk of ignition when centrifuging ether-containing materials. Furthermore, the amount of inert gas can be replenished through the gas tank 50 when the amount is insufficient.

[0031] Furthermore, the sealed space 12 is evenly divided into six parts around the central axis of the centrifugal disc 11 by a partition. The first group of three centrally symmetrical parts is connected to a first switching valve 112, and the second group of three centrally symmetrical parts is connected to a second switching valve. In this way, the first switching valve 112 can control the opening and closing of half of the sealed space 12, thereby allowing half or all of the vents 111 to be opened as needed. Furthermore, the first switching valve 112 can be an electrically controlled valve.

[0032] Furthermore, the system also includes a controller and a temperature sensor. The temperature sensor is adapted to monitor the temperature inside the tank 10. The temperature sensor is connected to the input terminal of the controller, and the output terminal of the controller is connected to the air pump 40. With this configuration, the temperature inside the tank 10 is monitored by the temperature sensor and fed back to the controller, thereby allowing the temperature inside the tank 10 to be controlled by adjusting the power of the air pump 40. Furthermore, the system also includes a control panel connected to the controller.

[0033] Furthermore, it also includes a suction pump, the input end of which is connected to the tank 10, and the output end of which is connected to the outside. This configuration allows the suction pump to quickly expel the air from inside the tank 10 and fill it with inert gas.

[0034] The above description is only a preferred embodiment of the present utility model and is not intended to limit the scope of protection of the present utility model. Any modifications, equivalent substitutions and improvements made by those skilled in the art within the spirit and principles of the present utility model should be included within the scope of protection of the present utility model.

Claims

1. A low-temperature centrifugation device for ether substances, comprising a body having a tank, wherein a centrifuge disc is coaxially arranged inside the tank, characterized in that, It also includes a gas pipe, a cooling assembly, a gas pump, and a gas tank. The centrifugal disc and the lower part of the tank form a sealed space. The bottom surface of the centrifugal disc is evenly provided with a number of air holes. The upper part of the tank is provided with a first exhaust port and a second exhaust port. One end of the gas pipe is connected to the first exhaust port, and the other end of the gas pipe is connected to the input end of the gas pump. The output end of the gas pump is connected to the sealed space. The cooling assembly is configured to cool the gas pipe. The gas tank stores inert gas and is branched onto the gas pipe. A valve is provided on the gas pipe.

2. The low-temperature centrifugation device for ether substances according to claim 1, characterized in that, The sealed space is evenly divided into six parts around the central axis of the centrifugal disc by a partition, and the three parts that are centrally symmetrical are connected to the first switching valve.

3. The low-temperature centrifugation device for ether substances according to claim 2, characterized in that, The first switching valve is an electrically controlled valve.

4. The low-temperature centrifugation device for ether substances according to claim 1, characterized in that, It also includes a controller and a temperature sensor, the temperature sensor being adapted to monitor the temperature inside the tank, the temperature sensor being connected to the input terminal of the controller, and the output terminal of the controller being connected to the air pump.

5. A low-temperature centrifuge device for ether substances according to claim 4, characterized in that, It also includes a control panel connected to the controller.

6. A low-temperature centrifuge apparatus for ether substances according to any one of claims 1-5, characterized in that, It also includes a suction pump, the input end of which is connected to the tank body, and the output end of which is connected to the outside.