Intelligent microbial limit detection sample subpackaging device capable of preventing cross contamination

Abstract

The utility model relates to an intelligent microbial limit detection sample subpackaging device capable of preventing cross contamination, which comprises a workbench and is technically characterized in that the workbench is a right-angle workbench, a cantilever support is arranged above the workbench, a rotary table is arranged on the upper surface of the cantilever support, a culture dish positioning groove is formed in the upper surface of the rotary table, and a discharging pipe is arranged in the center of the bottom of a culture dish; a lifting hollow pipe is arranged in the discharging pipe, the upper end and the lower end of the lifting hollow pipe are closed, a discharging hole is formed in the position, close to the upper end, of the lifting hollow pipe, the lower end of the lifting hollow pipe is fixedly connected with the telescopic end of the longitudinal push rod, an inclined branch communicated with the lifting hollow pipe is arranged on the lower portion of the lifting hollow pipe, and the lower end of the inclined branch is connected with a guide pipe. A horizontal conveying belt is arranged on the upper surface of the workbench, a plurality of detection bottles are arranged on the upper surface of the horizontal conveying belt at intervals, and a running track of the detection bottles passes through the lower portion of the guide pipe. According to the device, the problem of sample pollution caused by manual subpackaging is solved, and meanwhile, the subpackaging efficiency is improved.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical testing technology, specifically to an intelligent microbial limit testing sample dispensing device that prevents cross-contamination. Background Technology

[0002] Microbial limit testing is a method for examining the degree of microbial contamination of non-sterilized preparations and their raw materials and excipients. The test items include bacterial count, mold count, yeast count, and control bacteria test. The commonly used method in the existing technology is the microbial limit detection method, which detects microbiological limit indicators.

[0003] All raw materials and excipients used in pharmaceutical manufacturing must be tested for microbial limits. When conducting microbial limit tests, sample preparation should be carried out in a unidirectional airflow area. The general steps for sample preparation include: transferring sterilized containers and culture media to a unidirectional airflow area under clean conditions; adding a certain amount of the test sample to a culture medium solution at approximately 45°C and stirring thoroughly; adding a certain amount of the culture medium solution to a petri dish; and covering the petri dish to complete the sample preparation process. After sample preparation, it is generally aliquoted into individual test vials for testing to increase accuracy. However, currently, the aliquoting process is generally performed manually by operators, posing a risk of sample contamination. Utility Model Content

[0004] The purpose of this invention is to provide a reasonably structured, reliable, and cross-contamination-preventing intelligent microbial limit testing sample dispensing device, which solves the problem of sample contamination during manual dispensing and improves dispensing efficiency.

[0005] The technical solution of this utility model is:

[0006] A smart microbial limit testing sample dispensing device to prevent cross-contamination includes a workbench. The key technical features are: the workbench is a right-angled workbench with a cantilever frame above it; a turntable is mounted on the upper surface of the cantilever frame; a culture dish positioning groove concentric with the turntable is mounted on the upper surface of the turntable; a culture dish is placed in the positioning groove; a discharge pipe is located at the center of the bottom of the culture dish; a first clearance hole is located at the bottom of the positioning groove; a second clearance hole corresponding to the first clearance hole is located on the cantilever frame; and a discharge pipe is provided in the discharge pipe. The device includes a liftable hollow tube with its upper and lower ends closed and a discharge hole located near the upper end. The lower end of the liftable hollow tube is connected and fixed to the telescopic end of a longitudinal push rod, which is fixed to the upper surface of the worktable. The lower part of the liftable hollow tube has an inclined branch that communicates with it, and the lower end of the inclined branch is connected to a guide tube. A horizontal conveyor belt is provided on the upper surface of the worktable, and multiple test bottles are spaced apart on the upper surface of the horizontal conveyor belt. The running track of the test bottles passes under the guide tube.

[0007] The aforementioned intelligent microbial limit detection sample dispensing device for preventing cross-contamination has an infrared sensor on the end of the vertical wall of the right-angle workbench facing upwards towards the horizontal conveyor belt.

[0008] The aforementioned intelligent microbial limit detection sample dispensing device for preventing cross-contamination has a laser ranging sensor on the longitudinal push rod facing upwards towards the horizontal conveyor belt.

[0009] The aforementioned intelligent microbial limit detection sample dispensing device for preventing cross-contamination has a sealing structure between the unloading pipe and the liftable hollow pipe. The sealing structure consists of an annular sealing groove on the inner wall of the unloading pipe and an annular sealing filler in the annular sealing groove.

[0010] In the aforementioned intelligent microbial limit detection sample dispensing device for preventing cross-contamination, the upper end of the liftable hollow tube is connected to a small stirring paddle concentric with it.

[0011] The aforementioned intelligent microbial limit detection sample dispensing device for preventing cross-contamination has a spline sleeve on the inner peripheral wall of the positioning groove of the culture dish, and a spline structure that mates with the spline sleeve on the outer wall of the culture dish.

[0012] The aforementioned intelligent microbial limit detection sample dispensing device for preventing cross-contamination has an annular boss concentric with the bottom surface of the turntable, a bearing support structure between the annular boss and the cantilever frame, a gear ring structure on the outer circumference of the turntable, a motor reducer on the worktable, and a transmission gear meshing with the gear ring structure at the output end of the motor reducer.

[0013] The beneficial effects of this utility model are:

[0014] 1. The sample solution is dispensed into each test bottle using a turntable, longitudinal push rod, liftable hollow tube, oblique branch and guide tube. The horizontal conveyor belt is responsible for moving the test bottles into position in sequence. The whole process replaces manual dispensing, solves the problem of sample contamination caused by manual dispensing, and improves dispensing efficiency.

[0015] 2. The turntable drives the culture dish to rotate synchronously, and the adjustable hollow tube and small stirring paddle rotate relative to the culture dish. The small stirring paddle stirs the sample solution inside, further ensuring the uniformity of the distribution of substances in the solution, thereby ensuring the accuracy of the detection. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the structure of this utility model;

[0017] Figure 2 yes Figure 1 Top view;

[0018] Figure 3 yes Figure 1 Enlarged view of section A.

[0019] In the diagram: 1. Motor reducer, 2. Transmission gear, 3. Turntable, 4. Cap, 5. Petri dish, 6. Spline structure, 7. Gear ring structure, 8. Cantilever frame, 9. Guide tube, 10. Liftable hollow tube, 11. Longitudinal push rod, 12. Detection bottle, 13. Horizontal conveyor belt, 14. Workbench, 15. Infrared sensor, 16. Laser rangefinder sensor, 17. Small agitator, 18. Discharge pipe, 19. Annular sealing packing, 20. Discharge hole, 21. Angled branch. Detailed Implementation

[0020] The present invention will be described in detail with reference to the accompanying drawings.

[0021] like Figures 1-3 As shown, the intelligent microbial limit detection sample dispensing device for preventing cross-contamination includes a workbench 14.

[0022] The workbench 14 is a right-angled workbench with a cantilever frame 8 above it. A turntable 3 is mounted on the upper surface of the cantilever frame 8. A culture dish positioning groove, concentric with the turntable 3, is provided on the upper surface of the turntable 3. A culture dish 5 is placed in the culture dish positioning groove. In this embodiment, a spline sleeve is provided on the inner circumferential wall of the culture dish positioning groove, and a spline structure 6, which mates with the spline sleeve, is provided on the outer wall of the culture dish 5. A pressure cap 4 is fastened to the upper end of the culture dish 5. The bottom surface of the culture dish 5 is conical.

[0023] The bottom center of the petri dish 5 is provided with a discharge pipe 18, and the bottom of the petri dish positioning groove is provided with a first clearance hole. The cantilever frame 8 is provided with a second clearance hole corresponding to the first clearance hole. The discharge pipe 18 is provided with a liftable hollow tube 10. In this embodiment, a sealing structure is provided between the discharge pipe 18 and the liftable hollow tube 10. The sealing structure consists of an annular sealing groove provided on the inner wall of the discharge pipe 18 and an annular sealing filler 19 provided in the annular sealing groove. The upper and lower ends of the liftable hollow tube 10 are closed, and a discharge hole 20 is provided near the upper end. The lower end of the liftable hollow tube 10 is connected and fixed to the telescopic end of the longitudinal push rod 11. The longitudinal push rod 11 is fixed to the upper surface of the workbench 14. The lower part of the liftable hollow tube 10 is provided with an inclined branch 21 communicating with it. The lower end of the inclined branch 21 is connected to a guide tube 9. The upper end of the liftable hollow tube 10 is connected to a small stirring paddle 17 concentric with it.

[0024] The upper surface of the workbench 14 is provided with a horizontal conveyor belt 13, and a plurality of test bottles 12 are spaced apart on the upper surface of the horizontal conveyor belt 13. The running track of the test bottles 12 passes below the guide tube 9. In this embodiment, an infrared sensor 15 facing upwards toward the horizontal conveyor belt 13 is provided on the end section of the vertical wall of the right-angle workbench. A laser rangefinder sensor 16 facing upwards toward the horizontal conveyor belt 13 is provided on the longitudinal push rod 11.

[0025] The bottom surface of the turntable 3 is provided with an annular boss concentric with it. A bearing support structure is provided between the annular boss and the cantilever frame 8. The outer circumferential surface of the turntable 3 is provided with a gear ring structure 7. The worktable 14 is provided with a motor reducer 1. The output end of the motor reducer 1 is provided with a transmission gear 2 that meshes with the gear ring structure 7.

[0026] Working principle:

[0027] 1. When using, prepare the sample in petri dish 5. After preparation, put on the pressure cap 4.

[0028] 2. Start the motor reducer 1, and use the transmission gear 2 and gear ring structure 3 to drive the turntable 3 to rotate. The turntable 3 drives the petri dish 5 to rotate synchronously. Due to the positioning effect of the longitudinal push rod 11, the movable hollow tube 10 and the small stirring paddle 17 rotate relative to the petri dish 5. The small stirring paddle 17 then stirs the solution in it, further ensuring the uniformity of the distribution of substances in the solution.

[0029] 3. Start the horizontal conveyor belt 13 to move the first test bottle 12 to the top of the guide tube 9. After the laser rangefinder 16 detects that the bottle is in position, start the longitudinal push rod 11 to move the liftable hollow tube 10 upward. Then, its discharge hole 20 rises into the petri dish 5. The sample solution in the petri dish 5 flows into the first test bottle 12 through the discharge hole 20, the liftable hollow tube 10, the inclined branch 21 and the guide tube 9. After a set time, the longitudinal push rod 11 moves the liftable hollow tube 10 downward. The discharge hole 20 is closed by the discharge pipe 18 and no more material is discharged. After a set waiting time, the guide tube 9 stops discharging material. The horizontal conveyor belt 13 moves the first test bottle 12 forward, and the second test bottle 12 reaches the bottom of the guide tube 9.

[0030] 4. Similarly, complete the sample dispensing for the second test vial 12. Next, repeat the above operations to complete the sample dispensing for each of the remaining test vials 12.

[0031] 5. When the first test bottle 12 reaches the end of the right-angle workbench along the horizontal conveyor belt 13, the infrared sensor 15 detects the first test bottle 12, the horizontal conveyor belt 13 stops, and the dispensing operation is completed.

[0032] The embodiments of this utility model have been described in detail above, but the content described is only a preferred embodiment of this utility model and should not be considered as limiting the scope of implementation of this utility model. All equivalent changes and improvements made within the scope of this utility model should still fall within the scope of this utility model.

Claims

1. An intelligent microbial limit detection sample dispensing device to prevent cross-contamination, comprising a workbench, characterized in that: The workbench is a right-angled workbench with a cantilever frame above it. A turntable is mounted on the upper surface of the cantilever frame, and a petri dish positioning groove is concentrically located on the upper surface of the turntable. A petri dish is placed in the positioning groove, and a discharge pipe is located at the center of the bottom of each petri dish. A first clearance hole is located at the bottom of the positioning groove, and a second clearance hole corresponding to the first clearance hole is located on the cantilever frame. A liftable hollow tube is located within the discharge pipe, with its upper and lower ends closed and a discharge hole located near its upper end. The lower end of the liftable hollow tube is connected and fixed to the telescopic end of a longitudinal push rod, which is fixed to the upper surface of the workbench. A diagonal branch is connected to the lower part of the liftable hollow tube, and a guide tube is connected to the lower end of the diagonal branch. A horizontal conveyor belt is mounted on the upper surface of the workbench, and multiple test bottles are spaced apart on its upper surface. The running track of the test bottles passes below the guide tube.

2. The intelligent microbial limit detection sample dispensing device for preventing cross-contamination according to claim 1, characterized in that: An infrared sensor facing upwards toward the horizontal conveyor belt is installed on the vertical end of the right-angle workbench.

3. The intelligent microbial limit detection sample dispensing device for preventing cross-contamination according to claim 1, characterized in that: The longitudinal push rod is equipped with a laser rangefinder sensor facing upwards towards the horizontal conveyor belt.

4. The intelligent microbial limit detection sample dispensing device for preventing cross-contamination according to claim 1, characterized in that: A sealing structure is provided between the unloading pipe and the liftable hollow pipe. The sealing structure consists of an annular sealing groove on the inner wall of the unloading pipe and an annular sealing filler in the annular sealing groove.

5. The intelligent microbial limit detection sample dispensing device for preventing cross-contamination according to claim 1, characterized in that: The upper end of the liftable hollow tube is connected to a small stirring paddle concentric with it.

6. The intelligent microbial limit detection sample dispensing device for preventing cross-contamination according to claim 1, characterized in that: The inner circumferential wall of the positioning groove of the culture dish is provided with a spline sleeve, and the outer wall of the culture dish is provided with a spline structure that mates with the spline sleeve.

7. The intelligent microbial limit detection sample dispensing device for preventing cross-contamination according to claim 1, characterized in that: The bottom surface of the turntable is provided with an annular boss concentric with it. A bearing support structure is provided between the annular boss and the cantilever frame. A gear ring structure is provided on the outer circumference of the turntable. A motor reducer is provided on the worktable. The output end of the motor reducer is provided with a transmission gear that meshes with the gear ring structure.

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