Filter element for extracting chlorogenic acid from honeysuckle
By using a filter cartridge that includes a filter body, two large-pore resin filtration layers, and a supercritical CO2 extraction layer, combined with supercritical CO2 extraction technology, the problems of filtration precision and purity in the extraction of chlorogenic acid from honeysuckle have been solved, achieving a highly efficient and environmentally friendly chlorogenic acid extraction process.
Patent Information
- Application Number
- CN202520521887.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-24
- Publication Date
- 2026-02-27
- Estimated Expiration
- 2035-03-24
AI Technical Summary
In current methods for extracting chlorogenic acid from honeysuckle, the filtration precision is low, impurities are not thoroughly removed, and the purity of the extract is low, which affects product quality and long-term storage stability.
A filter element comprising a filter cartridge body, two large porous resin filtration layers, and a supercritical CO2 extraction layer is used. Filtering and extraction are performed using AB-8 and D101B resin layers, combined with supercritical CO2 extraction technology, to achieve the separation and purification of chlorogenic acid at room temperature.
It improves the extraction precision and purity of chlorogenic acid, ensures product quality stability, reduces the loss of effective components, lowers energy consumption and enterprise costs, and achieves a highly efficient impurity removal effect.
Smart Images
Figure CN223945042U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to the technical field of chlorogenic acid extraction, in particular to a filter core for extracting chlorogenic acid from honeysuckle. BACKGROUND
[0002] Honeysuckle, also known as honeysuckle or double flower, has the functions of clearing heat and detoxifying, dredging meridians, regulating immunity, broad-spectrum antibacterial, and antiviral. It has the functions of delaying aging, improving microcirculation, removing lipid peroxidation deposition, promoting metabolism, and moisturizing and removing spots. Honeysuckle is known as "Chinese medicine antibiotic" and "green antibiotic", and its main components include chlorogenic acid, isochlorogenic acid, and a small amount of volatile oil.
[0003] Traditional filtration of honeysuckle uses plate and frame, filter core, and diatomite to filter. The filtration precision is low, the impurities in the extract are not completely removed, the product purity is low, the product is turbid or precipitated after long-term storage, and the product quality and appearance are affected. Therefore, a new type of chlorogenic acid filter core is needed to solve the above problems. UTILITY MODEL CONTENT
[0004] (I) Technical problem solved
[0005] In view of the deficiencies of the prior art, the utility model provides a filter core for extracting chlorogenic acid from honeysuckle, to solve the problems of low filtration precision, incomplete impurity removal, and low extraction purity in the existing extraction of chlorogenic acid from honeysuckle.
[0006] (II) Technical scheme
[0007] The utility model provides the following technical scheme: a filter core for extracting chlorogenic acid from honeysuckle, comprising a filter core body, two macroporous resin filter layers and an ultra-zero boundary CO2 extraction layer arranged inside the filter core body, the ultra-zero boundary CO2 extraction layer is arranged between the two macroporous resin filter layers, one side of the filter core body is provided with a water inlet, and the other side is provided with a water outlet.
[0008] Preferably, the macroporous resin filter layer comprises an AB-8 resin layer and a D101B resin layer.
[0009] Preferably, the water inlet is communicated with the AB-8 resin layer, and the water outlet is communicated with the D101B resin layer.
[0010] (III) Beneficial effects
[0011] Compared with the prior art, the utility model provides a filter core for extracting chlorogenic acid from honeysuckle, which has the following beneficial effects:
[0012] 1. The filter core for extracting chlorogenic acid from honeysuckle, mainly comprising a filter core body, a macroporous resin filter layer and an ultra-zero boundary CO2 extraction layer, a solvent enters the filter core body through a water inlet, then the macroporous resin filter layer filters large-particle impurities in the solvent, then the ultra-zero boundary CO2 extraction layer extracts the solvent, then the D101B resin layer separates and purifies, and the extracted and filtered chlorogenic acid flows out through a water outlet, thereby ensuring the precision of chlorogenic acid extraction. BRIEF DESCRIPTION OF DRAWINGS
[0013] Fig. 1 Figure 1 is a structural schematic view of one embodiment of the filter core for extracting chlorogenic acid from honeysuckle.
[0014] Fig. 2 Figure 2 is a flowchart of the filter core for extracting chlorogenic acid from honeysuckle.
[0015] In the figure: 1, filter core body; 2, macroporous resin filter layer; 21, AB-8 resin layer; 22, D101B resin layer; 3, ultra-zero boundary CO2 extraction layer; 4, water inlet; 5, water outlet. DETAILED DESCRIPTION
[0016] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative labor fall within the scope of protection of the present application.
[0017] As introduced in the background, the existing problems in the prior art, in order to solve the above technical problems, the present application provides a filter core for extracting chlorogenic acid from honeysuckle.
[0018] Please refer to Figs. 1-2The application relates to a filter core for extracting chlorogenic acid from honeysuckle, which comprises a filter core body 1, two macroporous resin filter layers 2 arranged in the filter core body and an ultra-zero boundary CO2 extraction layer 3 arranged between the two macroporous resin filter layers 2, one side of the filter core body 1 is provided with a water inlet 4, and the other side is provided with a water outlet 5. The macroporous resin filter layer 2 comprises an AB-8 resin layer 21 and a D101B resin layer 22, the water inlet 4 is communicated with the AB-8 resin layer 21, and the water outlet 5 is communicated with the D101B resin layer 22. During the extraction of chlorogenic acid from honeysuckle, the solvent enters the filter core body 1 through the water inlet 4, then the macroparticles in the solvent are filtered through the AB-8 resin layer 21, then the solvent is extracted through the ultra-zero boundary CO2 extraction layer 3, then the solvent is separated and purified through the D101B resin layer 22, the filtered chlorogenic acid flows out through the water outlet 5, and is collected through a collecting device, so that the extraction precision of chlorogenic acid is ensured.
[0019] The chlorogenic acid extraction process parameters of the application are as follows: the pH value of the sample liquid is 4.0, the mass concentration is 2.0 mg / mL, the flow rate is 2.0 BV / h; the desorption liquid is an 80% ethanol solution, the flow rate of the desorption liquid is 2.0 BV / h, and the volume of the desorption liquid is 7.0 BV; the water layer is used for separating and purifying chlorogenic acid through D101B resin; the yield of chlorogenic acid is 89.71%, and the purity reaches 61.22%; the yield of total flavones is 93.45%, and the purity reaches 78.92%.
[0020] The filter core for extracting chlorogenic acid from honeysuckle of the application uses ultra-zero boundary CO2 as the solvent for extraction instead of water and ethanol, and uses macroporous resin adsorption for impurity removal and purification, so that the chlorogenic acid in honeysuckle is separated and purified. The filter core of the application is an ultrafiltration biological membrane, which mainly comprises two macroporous resin filter layers 2 and an ultra-zero boundary CO2 extraction layer 3. The two macroporous resin filter layers 2 comprise an AB-8 resin layer 21 and a D101B resin layer 22, so that the chlorogenic acid in honeysuckle can be stably and physically extracted at normal temperature without phase change, the AB-8 resin and the D101B resin are used for separation and purification, the safety and environmental protection are higher, the material is non-toxic and safe, the extraction time is short, the entire extraction and separation process are combined and performed at the same time, the extraction time is greatly shortened, and the biological activity and quality of the natural product are ensured.
[0021] In the chlorogenic acid extraction process, the supercritical CO2 extraction can separate the chlorogenic acid in honeysuckle, and the whole process can be performed at normal temperature, so that the stability and purity of the chlorogenic acid are fully ensured.
[0022] The application adopts the ultrafiltration membrane separation technology, and based on the selective screening principle of the high polymer membrane material, the macromolecular impurities in the honeysuckle extract are completely intercepted at the molecular level, so that the impurities are not easy to pass through the molecular sieve and be blocked on the membrane surface, the effective components pass through the membrane surface along with the filtrate by adopting the cross-flow operation mode, so that the separation and purification of the extract are realized, and the problem of filtration blocking is solved.
[0023] The application adopts the ultrafiltration membrane to filter the honeysuckle extract, and has the following advantages:
[0024] The effective components in the honeysuckle extract have relatively small molecular weight, and the ineffective components have relatively large molecular weight. Therefore, the ultrafiltration membrane separation technology can remove the high molecular weight impurities without losing the effective components. The ultrafiltration membrane technology selects the membranes with different pore sizes and operation parameters according to the molecular weight, structure, temperature, concentration, pH value and viscosity of the liquid medicine, intercepts the macromolecular impurities according to the selective screening principle of the membrane, makes the effective components of the honeysuckle pass through, intercepts the ineffective macromolecular components, and achieves the effects of cleaning and removing impurities and long-term storage without precipitation.
[0025] 1. The membrane filtration precision is high, the plant fibers, gum, starch and the like in the extract can be completely removed, the permeate is clear and transparent, and the product quality is high.
[0026] 2. The homogenization filtration can reduce the loss of the effective components.
[0027] 3. Concentration at normal temperature, no phase change and quality change, no damage to the effective components and heat-sensitive components, and low energy consumption.
[0028] 4. Reduce the consumption of consumables and reduce the enterprise cost.
[0029] Although the embodiments of the utility model have been shown and described, it can be understood by those skilled in the art that various changes, modifications, replacements and variations can be made to these embodiments without departing from the principles and spirits of the utility model, and the scope of the utility model is defined by the appended claims and their equivalents.
Claims
1. A filter core for extracting chlorogenic acid from honeysuckle, characterized in that, The filter core body, two macroporous resin filter layers arranged in the filter core body, and a super zero boundary CO2 extraction layer are arranged between the two macroporous resin filter layers.
2. The filter cartridge for extracting chlorogenic acid from honeysuckle according to claim 1, characterized in that, The macroporous resin filter layer comprises an AB-8 resin layer and a D101B resin layer.
3. The filter cartridge for extracting chlorogenic acid from honeysuckle according to claim 1, characterized in that, The water inlet is communicated with the AB-8 resin layer, and the water outlet is communicated with the D101B resin layer.