Kit integrated with sample pretreatment function
The reagent kit, which integrates homogenization and centrifugation storage mechanisms, solves the problem of time-consuming and labor-intensive sample pretreatment, achieving efficient and stable sample processing and improving experimental efficiency and sample quality.
Patent Information
- Application Number
- CN202520271225.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-02-20
- Publication Date
- 2026-02-27
- Estimated Expiration
- 2035-02-20
AI Technical Summary
Existing kits lack portable integrated devices during sample pretreatment, causing staff to spend a lot of time and effort on mixing and centrifugation, which affects efficiency.
A kit integrating sample pretreatment functions was designed, comprising a homogenization and fusion mechanism and a centrifugation and storage mechanism. The homogenization and fusion mechanism simulates artificial shaking, while the centrifugation and storage mechanism provides stable centrifugal force and low-temperature protection.
The kit, which integrates sample pretreatment functions, reduces manual operation time, improves sample processing efficiency and quality, and reduces operational errors.
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Figure CN223945489U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to reagent pretreatment box technical field, concretely is a reagent box of integration sample pretreatment function. BACKGROUND
[0002] A reagent kit is a standardized tool used in laboratories, designed to assist researchers in performing a series of specific experiments or analyses. It combines a series of chemical reagents, tools, and operating guidelines to ensure that users can conduct experiments in a unified operation process without additional preparation of reagents or handling of complex formulations. Typically, a reagent kit includes reagents required for a specific experiment (such as enzymes, buffers, dyes, etc.), reaction containers (such as microcentrifuge tubes), and detailed usage instructions. Its application range is wide, covering molecular biology, clinical testing, environmental analysis, and other fields. By using a reagent kit, experimenters can complete sample processing or testing in a shorter time, while reducing human error and uncertainty in operation. In many cases, reagent kits provide a relatively simple and standardized solution suitable for experiments that require fast and reliable results. They are not only used in laboratory daily work, but also widely used in pathological detection, disease diagnosis, and other practical scenarios.
[0003] During the sample processing stage, workers usually need to mix different reagents according to the preset steps. Workers usually need to gently mix the sample and reagents to ensure that the reagents are in full contact with the sample and are evenly distributed. This can be done through gentle shaking, centrifugation, or manual stirring, but there is currently no portable integrated device to assist workers, resulting in workers wasting time and effort when pre-processing samples. UTILITY MODEL CONTENT
[0004] The utility model aims at providing a reagent kit with integrated sample pretreatment function to solve the problems raised in the above background technology.
[0005] To achieve the above-mentioned purpose, the utility model provides the following technical scheme: a reagent kit with integrated sample pretreatment function, comprising a reagent processing box, a top cover rotatably connected to the upper side of the reagent processing box, and a cold air passage provided in communication with the inside of the reagent processing box. The reagent processing box is internally provided with a homogenization fusion mechanism and a centrifugal storage mechanism, and the homogenization fusion mechanism is arranged on one side of the centrifugal storage mechanism.
[0006] The homogeneous fusion mechanism includes a sliding frame, the sliding frame is fixedly connected to the inner wall of the reagent processing box, a reagent rack is slidably connected to the outer wall of the sliding frame, a hanging rod is fixedly connected to the lower side of the reagent rack, a sliding rod is slidably connected to the outer wall of the hanging rod, a support is fixedly connected to the inside of the reagent processing box, a swing frame is rotatably connected to the top of the support, the swing frame is rotatably connected to the sliding rod at the top end, a support table is fixedly connected to the inside of the reagent processing box, a hanging seat is fixedly connected to one side of the support table, a rocking motor is fixedly connected to the inside of the hanging seat, a crank is fixedly connected to the output end of the rocking motor, and the crank is slidably connected to the inside of the swing frame.
[0007] Preferably, the swing frame is provided with a sliding groove in the inside.
[0008] Preferably, a plurality of notches are uniformly formed in the inside of the reagent rack.
[0009] Preferably, ring structures are fixedly connected to the two ends of the sliding rod, and the ring structures are slidably connected to the outer wall of the hanging rod.
[0010] Preferably, the centrifugal storage mechanism includes a centrifugal motor, the centrifugal motor is fixedly connected to the inside of the reagent processing box, a centrifugal sleeve is fixedly connected to the output end of the centrifugal motor, a sliding block is slidably connected to the inside of the centrifugal sleeve, a return spring is fixedly connected to one end of the sliding block, a rotating sleeve is rotatably connected to the upper side of the centrifugal sleeve, a stabilizing frame is sleeved on the output end of the centrifugal motor, an output pipe is in communication between the stabilizing frame and the rotating sleeve, a support is fixedly connected to the inside of the reagent processing box, one side of the upper end of the support is fixedly connected with the stabilizing frame, a pressure transmission plate is slidably connected to the inside of the stabilizing frame, a pressure regulating spring is fixedly connected to one side of the pressure transmission plate, a push plate is fixedly connected to one side of the pressure regulating spring, a centering rod is arranged in the inside of the push plate, the centering rod is abutted with the output end of the centrifugal motor at one end surface, a threaded cylinder is rotatably connected to the inside of the reagent processing box, a limiting rod is fixedly connected to the inside of the reagent processing box, a reagent tray is slidably connected to the outside of the limiting rod, the reagent tray is threadedly connected with the threaded cylinder, and the output end of the centrifugal motor is fixedly connected with a centrifugal frame.
[0011] Preferably, the inner wall of the threaded cylinder is provided with a threaded structure, and the outer wall of the reagent tray is provided with a threaded structure.
[0012] Preferably, a plurality of centering rods and sliding blocks are arranged, a notch is formed in the inside of the upper side of the centrifugal sleeve, the inside of the stabilizing frame is in communication with the inside of the centrifugal sleeve through the output pipe, and the output pipe is provided in a hard structure.
[0013] Compared with the prior art, the reagent box with integrated sample pretreatment function has the following beneficial effects:
[0014] 1. The centrifugal storage mechanism is used for maintaining the stability of the centrifugal device when providing centrifugal force for the reagent, which provides the centering effect for the output shaft of the device by the centrifugal force, so that the device can rotate smoothly, thereby improving the centrifugal effect and improving the quality of the sample, and the external cold source can protect all the chambers at low temperature to prevent the sample from being affected during processing.
[0015] 2. The homogenization fusion mechanism is used for fusing the sample, which can simulate the action of shaking the reagent by the staff, avoiding the fatigue caused by the staff when processing more reagents, and the mechanism can assist the staff in processing the reagent, thereby improving the efficiency. BRIEF DESCRIPTION OF DRAWINGS
[0016] In order to more clearly illustrate the technical scheme in the embodiments of the present application, the following will briefly introduce the drawings needed in the embodiment description. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can also be obtained by those skilled in the art without creative labor.
[0017] Figure 1 The structure schematic diagram of the present application;
[0018] Figure 2 The internal appearance schematic diagram of the present application;
[0019] Figure 3 The cross-sectional structure schematic diagram of the present application;
[0020] Figure 4 The structure schematic diagram of the hanging rod in the present application;
[0021] Figure 5 The structure schematic diagram of the sliding block, centrifugal sleeve, stable frame and reagent tray in the present application.
[0022] In the figure: 1, reagent processing box; 2, top cover; 3, cold air passage; 4, homogenization fusion mechanism; 401, sliding frame; 402, reagent frame; 403, hanging rod; 404, sliding rod; 405, support column; 406, swing frame; 407, support table; 408, hanging seat; 409, shaking motor; 410, crank; 5, centrifugal storage mechanism; 501, centrifugal motor; 502, centrifugal sleeve; 503, sliding block; 504, return spring; 505, rotating sleeve; 506, stable frame; 507, output pipe; 508, support; 509, pressure transmission plate; 510, pressure regulating spring; 511, push plate; 512, centering rod; 513, threaded cylinder; 514, limiting rod; 515, reagent tray; 516, centrifugal frame. DETAILED DESCRIPTION
[0023] The technical solutions in the embodiments of the present application will be clearly and completely described with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments of the present application, all other embodiments obtained by those skilled in the art without creative efforts fall within the scope of the present application.
[0024] In the present application, unless otherwise explicitly specified and limited, the terms "mounting", "connection", "connecting", "fixing" and the like should be understood in a broad sense, for example, can be fixed connection, or detachable connection, or integrated; can be mechanical connection, or electrical connection; can be directly connected, or indirectly connected through an intermediate medium; can be the internal communication of two elements or the interaction relationship between two elements. For those skilled in the art, the specific meanings of the above terms in the present application can be understood according to the specific circumstances.
[0025] Embodiment one:
[0026] The mechanism is used for providing fusion for samples, and solves the problem of time and labor consumption when a user processes samples in batches, please refer to Figures 1-5 The present application provides a technical scheme: a reagent box integrated with sample pretreatment function, comprising a reagent processing box 1, a top cover 2 rotatably connected to the upper side of the reagent processing box 1, and a cold air passage 3 arranged in communication with the inside of the reagent processing box 1, a homogenizing and fusing mechanism 4 and a centrifugal storage mechanism 5 are arranged in the reagent processing box 1, the homogenizing and fusing mechanism 4 is arranged on one side of the centrifugal storage mechanism 5.
[0027] The homogenizing and fusing mechanism 4 comprises a sliding frame 401 fixedly connected to the inner wall of the reagent processing box 1, a reagent rack 402 slidably connected to the outer wall of the sliding frame 401, a hanging rod 403 fixedly connected to the lower side of the reagent rack 402, a sliding rod 404 slidably connected to the outer wall of the hanging rod 403, a support column 405 fixedly connected to the inside of the reagent processing box 1, a swing rack 406 rotatably connected to the top of the support column 405, the swing rack 406 being rotatably connected to the top end of the sliding rod 404, a support table 407 fixedly connected to the inside of the reagent processing box 1, a hanging seat 408 fixedly connected to one side of the support table 407, a shaking motor 409 fixedly connected to the inside of the hanging seat 408, a crank 410 fixedly connected to the output end of the shaking motor 409, the crank 410 being slidably connected to the inside of the swing rack 406, a plurality of air flow channels are formed in the inside of the reagent processing box 1, and the cold air passage 3 provides cold air flow for the inside of the reagent processing box 1 through the air flow channels.
[0028] Further, a sliding groove is formed in the inside of the swing rack 406.
[0029] Further, a plurality of notches are uniformly formed in the inside of the reagent rack 402.
[0030] Further, the sliding rod 404 is fixedly connected with a ring structure at both ends, and the ring structure is slidingly connected to the outer wall of the hanging rod 403.
[0031] Embodiment two:
[0032] The mechanism is used for providing centrifugal pretreatment for samples, and solves the problem of insufficient sample quality caused by unstable centrifugation of the centrifugal device, please refer to Figures 1-5 , and in combination with embodiment one, it is further obtained that the centrifugal storage mechanism 5 comprises a centrifugal motor 501 fixedly connected inside the reagent processing box 1, a centrifugal sleeve 502 fixedly connected at the output end of the centrifugal motor 501, a sliding block 503 slidingly connected inside the centrifugal sleeve 502, a return spring 504 fixedly connected at one end of the sliding block 503, a rotating sleeve 505 rotatably connected to the upper side of the centrifugal sleeve 502, a stabilizing frame 506 sleeved on the output end of the centrifugal motor 501, an output pipe 507 in communication between the stabilizing frame 506 and the rotating sleeve 505, a support 508 fixedly connected inside the reagent processing box 1, the support 508 being fixedly connected at the upper end on one side of the stabilizing frame 506, a pressure transmission plate 509 slidingly connected inside the stabilizing frame 506, a pressure regulating spring 510 fixedly connected on one side of the pressure transmission plate 509, a push plate 511 fixedly connected on one side of the pressure regulating spring 510, a centering rod 512 provided inside the push plate 511, the centering rod 512 being abutted on one end surface with the output end of the centrifugal motor 501, a threaded cylinder 513 rotatably connected inside the reagent processing box 1, a limiting rod 514 fixedly connected inside the reagent processing box 1, a reagent tray 515 slidingly connected outside the limiting rod 514, the reagent tray 515 being threadedly connected with the threaded cylinder 513, a centrifugal frame 516 fixedly connected at the output end of the centrifugal motor 501, and the sliding block 503 can be provided in multiple groups and uniformly distributed inside the centrifugal sleeve 502.
[0033] In actual operation process, when the device is used, the user can add reagent to the sample and put it into the reagent frame 402 inside when the user needs to batch mix the sample, then the user starts the shaking motor 409, the shaking motor 409 drives the swing frame 406 to produce reciprocating motion when the output, the swing frame 406 drags the reagent frame 402 to mix the sample, when the user needs to centrifuge the sample, the user can put the sample into the centrifugal frame 516, then the user starts the centrifugal motor 501, the centrifugal motor 501 drives the centrifugal sleeve 502 to rotate when the output, the sliding block 503 inside the centrifugal sleeve 502 is slidingly connected under the centrifugal action and makes the hydraulic pressure in the centrifugal sleeve 502 transmit to the stabilizing frame 506, then the hydraulic pressure pushes the centering rod 512 to make the output end of the centrifugal motor 501 more stable, the user can store the sample in the tray and refrigerate the sample in the reagent processing box 1 by rotating the threaded cylinder 513.
[0034] It is to be noted that, as used in this specification and the appended claims, the singular forms "a," "an," and "the" include plural referents unless the context clearly dictates otherwise. Thus, for example, reference to "a component" can include a combination of two or more components. Additionally, the terms "comprise," "comprises," and "comprising," or any variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements is not necessarily limited to those elements, but can include other elements not expressly listed or inherent to such process, method, article, or apparatus. Furthermore, unless otherwise indicated herein, the terms "first," "second," "third," etc., are used herein merely as labels, and are not intended to impose ordinal import.
Claims
1. A kit integrated with sample pretreatment function, comprising a reagent processing box (1), a top cover (2) rotatably connected to the upper side of the reagent processing box (1), and a cold air passage (3) arranged in communication with the inside of the reagent processing box (1), characterized in that: The reagent processing box (1) is internally provided with a homogenization and fusion mechanism (4) and a centrifugal storage mechanism (5), and the homogenization and fusion mechanism (4) is arranged on one side of the centrifugal storage mechanism (5); The homogenization and fusion mechanism (4) comprises a sliding frame (401) fixedly connected to the inner wall of the reagent processing box (1), a reagent rack (402) slidably connected to the outer wall of the sliding frame (401), a hanging rod (403) fixedly connected to the lower side of the reagent rack (402), a sliding rod (404) slidably connected to the outer wall of the hanging rod (403), a support column (405) fixedly connected to the inside of the reagent processing box (1), a swing frame (406) rotatably connected to the top of the support column (405), the swing frame (406) being rotatably connected to the sliding rod (404) at the top end, a support table (407) fixedly connected to the inside of the reagent processing box (1), a hanging seat (408) fixedly connected to one side of the support table (407), a rocking motor (409) fixedly connected to the inside of the hanging seat (408), a crank (410) fixedly connected to the output end of the rocking motor (409), and the crank (410) being slidably connected to the inside of the swing frame (406).
2. The kit of claim 1, wherein: The swing frame (406) is internally provided with a sliding groove.
3. The kit of claim 1, wherein: A plurality of notches are uniformly formed in the inside of the reagent rack (402).
4. The kit of claim 1, wherein: The sliding rod (404) is fixedly connected with a ring structure at both ends, and the ring structure is slidably connected to the outer wall of the hanging rod (403).
5. The kit of claim 1, wherein: The centrifugal storage mechanism (5) comprises a centrifugal motor (501) fixedly connected to the inside of the reagent processing box (1), a centrifugal sleeve (502) fixedly connected to the output end of the centrifugal motor (501), a sliding block (503) slidably connected to the inside of the centrifugal sleeve (502), a return spring (504) fixedly connected to one end of the sliding block (503), a rotating sleeve (505) rotatably connected to the upper side of the centrifugal sleeve (502), a stable frame (506) sleeved on the output end of the centrifugal motor (501), an output pipe (507) in communication between the stable frame (506) and the rotating sleeve (505), a support (508) fixedly connected to the inside of the reagent processing box (1), the upper end of the support (508) being fixedly connected to one side of the stable frame (506), a pressure transmission plate (509) slidably connected to the inside of the stable frame (506), a pressure regulating spring (510) fixedly connected to one side of the pressure transmission plate (509), a push plate (511) fixedly connected to one side of the pressure regulating spring (510), a centering rod (512) provided in the inside of the push plate (511), the centering rod (512) being abutted to the output end of the centrifugal motor (501) at one end surface, a threaded cylinder (513) rotatably connected to the inside of the reagent processing box (1), a limiting rod (514) fixedly connected to the inside of the reagent processing box (1), a reagent tray (515) slidably connected to the outside of the limiting rod (514), the reagent tray (515) being threadedly connected to the threaded cylinder (513), and a centrifugal rack (516) fixedly connected to the output end of the centrifugal motor (501).
6. The kit of claim 5, wherein: The inner wall of the threaded cylinder (513) is provided with a threaded structure, and the outer wall of the reagent tray (515) is provided with a threaded structure.
7. The kit of claim 5, wherein: A plurality of centering rods (512) and sliding blocks (503) are arranged, a notch is arranged in the upper inner side of the centrifugal sleeve (502), the inner side of the stabilizing frame (506) is arranged in communication with the inner side of the centrifugal sleeve (502) through an output pipe (507), and the output pipe (507) is arranged in a hard structure.