Decalcification instrument

By designing the rotation and movement mechanism and purification system in the decalcification instrument, the problems of long decalcification time, uneven decalcification, and odor pollution in traditional decalcification methods have been solved, achieving efficient and uniform decalcification treatment while ensuring operational safety and environmental protection.

CN223966329UActive Publication Date: 2026-03-03GUANGZHOU WEXIS BIOTECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-03-24
Publication Date
2026-03-03

AI Technical Summary

Technical Problem

Traditional decalcification methods suffer from problems such as long decalcification time, uneven decalcification, and odor contamination, which affect the accuracy of tissue section observation and diagnosis.

Method used

A decalcification instrument was designed, comprising a storage container, a sample container, a rotation drive mechanism, a lateral drive mechanism, and a lifting drive mechanism. By rotating and moving the sample container within the storage container, the tissue sample is ensured to have full contact with the decalcification solution. The instrument is also equipped with a purification system and a temperature control system to reduce odor and contamination.

Benefits of technology

It improves decalcification efficiency and uniformity, reduces odor leakage, and ensures operational safety and environmental protection.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a decalcification instrument which comprises a machine body, the liquid storage container is arranged in the machine body and is used for storing decalcification liquid; the sample container is used for storing tissue samples, and a plurality of hollow holes are formed in the sample container; the rotation driving mechanism is used for driving the sample container to rotate around a vertical axis; the transverse movement driving mechanism is used for driving the sample container to move transversely; the lifting driving mechanism is used for driving the sample container to vertically move. According to the decalcification instrument, the sample container can move up and down and rotate in the liquid storage container, so that the tissue sample in the sample container is fully contacted with the decalcification liquid in the liquid storage container, the condition that part of the tissue sample cannot be fully contacted with the liquid storage container for reaction is avoided, and the decalcification efficiency and the decalcification uniformity are further improved.
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Description

Technical Field

[0001] This utility model relates to the field of decalcification instruments, and in particular to a decalcification instrument. Background Technology

[0002] In medical pathology research and diagnosis, decalcification of calcium-containing tissue specimens is a crucial step. When preparing sections, calcium-containing tissues, such as bone, are frequently encountered. The calcium in these tissues is very hard and has a different density than paraffin, so they generally cannot be directly sectioned. Furthermore, other tissues besides bone can also calcify, forming calcified areas. These calcified tissues also require decalcification for pathological research or diagnosis to facilitate sectioning and observation. Generally, a corresponding decalcification solution is prepared for each type of tissue sample. Decalcification is achieved by immersing the tissue sample in the solution for an extended period. However, traditional decalcification methods suffer from problems such as long decalcification times and uneven decalcification, affecting the accuracy of subsequent tissue section observation and diagnosis. In addition, the decalcification process generates an odor, causing discomfort to operators and posing a risk of environmental pollution. Utility Model Content

[0003] In view of this, the present invention proposes a decalcification instrument, the purpose of which is to improve the efficiency and uniformity of decalcification treatment to at least a certain extent.

[0004] The solution provided by this utility model includes:

[0005] A decalcification device, comprising:

[0006] Organism;

[0007] A liquid storage container, disposed within the body of the machine, is used to store the decalcification solution;

[0008] A sample container for storing tissue samples, wherein the sample container has multiple perforations;

[0009] A rotary drive mechanism for driving the sample container to rotate about a vertical axis;

[0010] A lateral movement drive mechanism is used to drive the sample container to move laterally;

[0011] A lifting drive mechanism is used to drive the sample container to move vertically.

[0012] As a further optional solution, the machine body is provided with an experimental chamber, and the liquid storage container, sample container, rotary drive mechanism, transverse drive mechanism and lifting drive mechanism are all located in the experimental chamber.

[0013] The machine body is also equipped with a purification system, which is connected to the experimental chamber to filter and purify the air inside the experimental chamber.

[0014] As a further optional solution, the purification system includes an air handling module, an air intake duct, and an air supply duct;

[0015] The air handling module includes a housing, and a fan and an air filter assembly are disposed inside the housing;

[0016] One end of the air inlet duct is connected to the experimental chamber, and the other end is connected to the shell.

[0017] One end of the air supply duct is connected to the experimental chamber, and the other end is connected to the shell.

[0018] The experimental chamber, air inlet duct, shell, and air supply duct sequentially form an air circulation path, and the air filter assembly is located on the air circulation path.

[0019] As a further alternative, a temperature control system is also included, which includes a temperature sensor and a heater disposed in the air circulation path.

[0020] As a further alternative, the heater is disposed within the housing.

[0021] As a further optional solution, the transverse drive mechanism is a horizontally arranged screw transmission module, the transverse drive mechanism is fixedly mounted on the machine body, and a first movable seat is provided on the transverse drive mechanism;

[0022] The lifting drive mechanism is a vertically arranged screw transmission module. The lifting drive mechanism is mounted on a first movable seat, and a second movable seat is mounted on the lifting drive mechanism.

[0023] The rotation drive mechanism is mounted on the second movable seat. The rotation drive mechanism includes a motor and a rotating body driven by the motor to rotate. The rotating body is connected to the sample container.

[0024] As a further optional solution, the experimental chamber is provided with a removable splash guard, and the liquid storage container is disposed in the splash guard.

[0025] As a further optional solution, multiple liquid storage containers are provided, and the multiple liquid storage containers are arranged in the anti-splash groove along the lateral driving direction of the lateral driving mechanism.

[0026] As a further optional feature, one side of the body is provided with a door for opening the experimental chamber.

[0027] As a further optional feature, the body is provided with a transparent observation window.

[0028] Compared with the prior art, the decalcification device of this application has at least the following advantages:

[0029] This decalcification instrument allows the sample container to move up and down and rotate within the storage container, ensuring that the tissue sample in the sample container fully contacts the decalcification solution in the storage container. This avoids situations where some tissue samples cannot fully contact and react with the storage container, thereby improving decalcification efficiency and uniformity. Attached Figure Description

[0030] Figure 1 This is a schematic diagram of the structure of a decalcification instrument according to an embodiment of the present invention;

[0031] Figure 2 This is a schematic diagram of the internal structure of the experimental chamber in a decalcification apparatus according to an embodiment of this utility model;

[0032] Figure 3 This is a schematic diagram of the purification system in an embodiment of the present utility model;

[0033] Figure 4 yes Figure 2 Enlarged view of A in the middle;

[0034] Figure 5 yes Figure 3 Enlarged view of B in the middle;

[0035] In the diagram: 1. Body; 11. Experimental chamber; 111. Air inlet; 112. Air outlet; 12. Door; 13. Transparent observation window; 2. Liquid storage container; 3. Sample container; 4. Lateral movement drive mechanism; 41. First moving seat; 5. Lifting drive mechanism; 51. Second moving seat; 6. Rotation drive mechanism; 61. Motor; 62. Rotating body; 7. Purification system; 71. Air handling module; 711. Shell; 712. Fan; 713. Air filter assembly; 72. Air inlet duct; 73. Air outlet duct; 8. Temperature control system; 81. Heater; 82. Temperature sensor; 9. Splash guard. Detailed Implementation

[0036] The specific embodiments of this utility model will be further described in detail below with reference to the accompanying drawings and examples. The following examples are used to illustrate this utility model, but are not intended to limit the scope of this utility model.

[0037] In the description of this utility model, it should be understood that the terms "upper", "lower", "front", "rear", "vertical", "horizontal", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0038] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0039] In this utility model, unless otherwise explicitly specified and limited, "above" or "below" the second feature can mean that the first feature is in direct contact with the second feature, or that the first feature is in indirect contact through an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0040] refer to Figure 1-5 An embodiment of this utility model illustrates a decalcification device, comprising a body 1, a liquid storage container 2, a sample container 3, a rotation drive mechanism 6, a lateral movement drive mechanism 4, and a lifting drive mechanism 5; the liquid storage container 2 is disposed within the body 1 and is used to store decalcification liquid; the sample container 3 is used to store tissue samples and has multiple perforated holes (not marked in the figure); the rotation drive mechanism 6 is used to drive the sample container 3 to rotate around a vertical axis; the lateral movement drive mechanism 4 is used to drive the sample container 3 to move laterally; and the lifting drive mechanism 5 is used to drive the sample container 3 to move vertically.

[0041] Specifically, the sample container 3 moves in space through the transverse drive mechanism 4 and the lifting drive mechanism 5, so that the sample container 3 can be immersed in the liquid storage container 2 and leave the liquid storage container 2; while the rotation drive mechanism 6 can make the sample container 3 rotate in the liquid storage container 2.

[0042] In application, sample container 3 is positioned above (not necessarily directly above) the liquid storage container 2. After the tissue sample is placed in sample container 3, the lateral movement drive mechanism 4 moves sample container 3 laterally, aligning sample container 3 vertically with the liquid storage container 2. Then, the lifting drive mechanism 5 lowers sample container 3, allowing at least a portion of sample container 3 to enter the liquid storage container 2. The decalcification solution in the liquid storage container 2 enters sample container 3 through the perforated holes, allowing the tissue sample to contact and react with the decalcification solution. During soaking, sample container 3 can be rotated by rotation drive mechanism 6 or raised and lowered by lifting drive mechanism 5, ensuring that the tissue sample in sample container 3 is fully soaked. This avoids the situation where tissue samples are stacked, resulting in some tissue samples not being fully decalcified, thereby improving decalcification efficiency and uniformity.

[0043] In the above-mentioned scheme, the tissue sample in the decalcification solution is not stirred by a stirring component, which can avoid the tissue sample being broken or damaged by the stirring component. In this embodiment, the tissue sample is placed in the sample container 3, and then the sample container 3 is driven to move by the lifting drive mechanism 5 and the rotating drive mechanism 6, so as to achieve full contact reaction between the tissue sample and the decalcification solution in a gentler way.

[0044] In some embodiments, such as Figure 2 and Figure 3 As shown, the machine body 1 contains an experimental chamber 11, within which the liquid storage container 2, sample container 3, rotary drive mechanism 6, lateral drive mechanism 4, and lifting drive mechanism 5 are all housed. The machine body 1 also includes a purification system 7, which is connected to the experimental chamber 11 to filter and purify the air within it. This purification system 7 effectively filters and purifies the air within the experimental chamber 11, promptly eliminating odors generated during the decalcification process, reducing the leakage of chemical gases to the outside of the instrument, preventing discomfort for operators, and minimizing environmental pollution.

[0045] In some more specific embodiments, such as Figure 5 As shown, the purification system 7 includes an air handling module 71, an air inlet duct 72, and an air supply duct 73. The air handling module 71 includes a housing 711, within which a fan 712 and an air filter assembly 713 are disposed. One end of the air inlet duct 72 is connected to the experimental chamber 11, and the other end is connected to the housing 711. One end of the air supply duct 73 is connected to the experimental chamber 11, and the other end is connected to the housing 711. The experimental chamber 11, the air inlet duct 72, the housing 711, and the air supply duct 73 sequentially form an air circulation path, and the air filter assembly 713 is located on the air circulation path.

[0046] The experimental chamber 11 is equipped with an air inlet 111 and an air outlet 112. An air inlet duct 72 connects to the experimental chamber 11 through the air inlet 111, and an air outlet duct 73 connects to the experimental chamber 11 through the air outlet 112. A fan 712 provides the power for airflow, drawing air from the experimental chamber 11 into the air handling module 71 through the air inlet duct 72. The air is then filtered and purified by an air filter assembly 713 inside the air handling module 71, trapping odor molecules. The purified air is then reintroduced into the experimental chamber 11 through the air outlet duct 73. In this embodiment, the air filter assembly 713 uses a high-efficiency composite filter; in other embodiments, other filter materials may be used without limitation.

[0047] In some embodiments, such as Figure 5 As shown, the system also includes a temperature control system 8, which comprises a temperature sensor 82 and a heater 81. The heater 81 is disposed on the air circulation path. In this embodiment, the heater 81 is disposed inside the housing 711, and the temperature sensor 82 is disposed on the air inlet duct 72. In this embodiment, the heater 81 is a PTC heater. The temperature sensor 82 detects the air temperature, and the heater 81 heats the air to adjust it to a preset temperature, thus maintaining the temperature inside the experimental chamber 11 at a suitable level for decalcification treatment.

[0048] In some embodiments, to facilitate the movement of the sample container 3, such as Figure 2 and Figure 4 As shown, the transverse drive mechanism 4 is a horizontally arranged screw transmission module, which is fixedly mounted on the machine body 1, and a first movable seat 41 is provided on the transverse drive mechanism 4; the lifting drive mechanism 5 is a vertically arranged screw transmission module, which is mounted on the first movable seat 41, and a second movable seat 51 is provided on the lifting drive mechanism 5; the rotation drive mechanism 6 is mounted on the second movable seat 51, and the rotation drive mechanism 6 includes a motor 61 and a rotating body 62 driven by the motor 61 to rotate, and the rotating body 62 is connected to the sample container 3.

[0049] In this embodiment, the sample container 3 is a hanging basket with multiple hollow holes, and the sample container 3 is suspended on the rotating body 62; the rotating body 62 can be any structure such as a rod, a hanger, or a hook.

[0050] In some embodiments, to prevent decalcification solution from splashing into the experimental chamber 11 and causing contamination when the sample container 3 is rotated, such as... Figure 2 and Figure 4As shown, the experimental chamber 11 is equipped with a removable splash guard 9, and the liquid storage container 2 is disposed within the splash guard 9. Thus, when the decalcification solution splashes out from the liquid storage container 2, the decalcification solution can fall into the splash guard 9. After the decalcification process is completed, the splash guard 9 can be removed for cleaning, facilitating instrument maintenance.

[0051] Preferably, multiple liquid storage containers 2 are provided, and the multiple liquid storage containers 2 are arranged in the anti-splash tank 9 along the lateral driving direction of the lateral driving mechanism 4. Furthermore, a sponge can be placed in the anti-splash tank 9 to fix the position of the liquid storage containers 2, while also absorbing the decalcification liquid that falls into the anti-splash tank 9.

[0052] In some embodiments, such as Figure 1 As shown, one side of the body 1 is provided with a door 12 for opening the experimental chamber 11, which facilitates the handling of tissue samples, decalcification solution and other operations.

[0053] In addition, the body 1 is provided with a transparent observation window 13, through which the decalcification situation in the experimental chamber 11 can be observed; in this embodiment, the transparent observation window 13 is located on the top of the body 1; in other embodiments, the transparent observation window 13 can also be located in other positions, as long as it is convenient for the operator to observe.

[0054] In summary, this utility model provides a decalcification instrument that allows the sample container 3 to move up and down and rotate within the liquid storage container 2, ensuring that the tissue sample in the sample container 3 fully contacts the decalcification solution in the liquid storage container 2. This avoids situations where some tissue samples cannot fully contact and react with the liquid storage container 2, thereby improving decalcification efficiency and uniformity.

[0055] In the above embodiments, the descriptions of each embodiment have different focuses. For parts not described in detail in a certain embodiment, please refer to the relevant descriptions of other embodiments.

[0056] The above description is only a preferred embodiment of the present utility model. It should be noted that for those skilled in the art, several improvements and substitutions can be made without departing from the technical principles of the present utility model, and these improvements and substitutions should also be considered within the protection scope of the present utility model.

Claims

1. A decalcifier, characterized by comprising: The device comprises: a machine body; a liquid storage container arranged in the machine body for storing decalcification solution; a sample container for storing a tissue sample, the sample container being provided with a plurality of hollow holes; a rotation driving mechanism for driving the sample container to rotate around a vertical axis; a horizontal movement driving mechanism for driving the sample container to move horizontally; a vertical movement driving mechanism for driving the sample container to move vertically.

2. The decalcification device according to claim 1, wherein: the machine body is provided with an experimental chamber, and the liquid storage container, the sample container, the rotation driving mechanism, the horizontal movement driving mechanism and the vertical movement driving mechanism are arranged in the experimental chamber; the machine body is further provided with a purification system, and the purification system is communicated with the experimental chamber to filter and purify the air in the experimental chamber.

3. The decalcification device according to claim 2, wherein: the purification system comprises an air treatment module, an air inlet pipeline and an air outlet pipeline; the air treatment module comprises a shell, and a fan and an air filter assembly are arranged in the shell; one end of the air inlet pipeline is connected to the experimental chamber, and the other end is connected to the shell; one end of the air outlet pipeline is connected to the experimental chamber, and the other end is connected to the shell; wherein the experimental chamber, the air inlet pipeline, the shell and the air outlet pipeline sequentially form an air circulation flow path, and the air filter assembly is located on the air circulation flow path.

4. The decalcification device according to claim 3, wherein: a temperature control system is further included, and the temperature control system comprises a temperature sensor and a heater, and the heater is arranged on the air circulation flow path.

5. The decalcification device according to claim 4, wherein: the heater is arranged in the shell.

6. The decalcification device according to any one of claims 2-5, wherein: the horizontal movement driving mechanism is a horizontally arranged lead screw transmission module, the horizontal movement driving mechanism is fixedly arranged on the machine body, and a first moving seat is arranged on the horizontal movement driving mechanism; the vertical movement driving mechanism is a vertically arranged lead screw transmission module, the vertical movement driving mechanism is arranged on the first moving seat, and a second moving seat is arranged on the vertical movement driving mechanism; the rotation driving mechanism is arranged on the second moving seat, the rotation driving mechanism comprises a motor and a rotating body driven to rotate by the motor, and the rotating body is connected to the sample container.

7. The decalcification device according to claim 6, wherein: a detachable splash-proof groove is arranged in the experimental chamber, and the liquid storage container is arranged in the splash-proof groove.

8. The decalcification device according to claim 7, wherein: a plurality of liquid storage containers are arranged, and the plurality of liquid storage containers are arranged in the splash-proof groove along the horizontal movement driving direction of the horizontal movement driving mechanism.

9. The decalcification device according to claim 2, wherein: one side of the machine body is provided with a box door for opening the experimental chamber.

10. The decalcification device according to claim 9, wherein: a transparent observation window is arranged on the machine body.