Glass chromatographic column convenient to operate

Abstract

The utility model relates to the technical field of glass chromatographic column accessory devices, in particular to a glass chromatographic column convenient to operate and a glass chromatographic column convenient to disassemble, assemble and operate. According to the glass chromatographic column convenient to operate, residues in the glass chromatographic column can be conveniently poured out and cleaned after separation is finished, so that the practicability is enhanced. Comprising two sets of supporting frames, a supporting table, a distribution box, an intelligent touch screen, an electric brake, a wiring mainboard, a first rotating rod, a second rotating rod, a rotating rod, a connecting ring, two sets of middle section glass separation columns and two sets of glass covers, the bottom ends of the two sets of supporting frames are each provided with a supporting and fixing assembly, and the front end of the supporting frame on the front side is connected with the supporting table; the front end of the front side supporting frame is connected with the distribution box, a hinged box door is arranged at the front end of the distribution box, and a cavity is formed in the distribution box.

Description

Technical Field

[0001] This utility model relates to the technical field of glass chromatography column accessories, and in particular to a glass chromatography column that is easy to operate. Background Technology

[0002] As is well known, glass chromatography columns are a commonly used separation and analysis tool, widely used in industries such as biochemistry and pharmaceuticals. Traditional glass chromatography columns typically consist of components such as the column body, sintered glass core, inlet, and outlet.

[0003] Glass chromatography columns are typically filled with silica gel powder between 100 and 400 mesh, used to separate impurities from compounds and purify them.

[0004] The conventional usage of existing technology is as follows: First, a certain amount of silica gel powder is loaded into the column. At this time, the silica gel powder is very loose, and negative pressure is used to compact the silica gel in the column. Then, the mixed sample (mixing the sample means that the compound and a certain amount of silica gel powder are mixed with solvent in advance, and then the solvent is concentrated to allow the compound to be adsorbed on the silica gel powder) is poured into the column. Then, eluent is added from the top of the column, and the eluent is collected from the bottom through negative pressure. The addition and collection of eluent are repeated to dissolve and elute the compound adsorbed on the silica gel. The compound is repeatedly adsorbed and eluted in the silica gel on the column. Based on the different polarities of the various components in the compound and their different solubilities in the eluent, the impurities in the compound can be separated, thus achieving the purpose of purifying the compound.

[0005] Such a large column typically contains over ten kilograms of silica powder. After use, several people have to lift the column, tilt it at a certain angle, and pour out the silica powder, which is time-consuming and laborious. Utility Model Content

[0006] To solve the above-mentioned technical problems, this utility model provides a glass chromatography column that is easy to disassemble and operate. The first and second chromatography column fixing components facilitate the disassembly of the pipeline, thereby facilitating the pouring out and cleaning of silica powder in the glass chromatography column after separation, thus enhancing the practicality of the glass chromatography column.

[0007] This utility model discloses an easy-to-operate glass chromatography column, comprising two sets of support frames, a support platform, a power distribution box, a smart touch screen, a power switch, a wiring main board, a first rotating rod, a second rotating rod, a rotating rod, a connecting ring, two sets of middle-section glass chromatography columns, and two sets of glass covers. Support and fixing components are respectively provided at the bottom of the two sets of support frames. The front end of the front support frame is connected to the support platform, on which a rotating component is provided. The front end of the front support frame is connected to the power distribution box, which has a hinged door at its front. A chamber is provided inside the power distribution box, and the rear end of the chamber is connected to the smart touch screen, the power switch, and the wiring main board. An angle is provided at the rear end of the rear support frame. The degree detection component has a first rotating rod bearing seal that passes through the front support frame, a second rotating plate that is connected to the rotating rod, and a rotating rod bearing seal that extends out of the rear end of the rear support frame. The inner ends of the first and second rotating plates are respectively connected to a connecting ring. The top and bottom ends of the connecting ring are provided with a first column fixing component. The top and bottom ends of the connecting ring are respectively provided with a first retaining ring groove. A first sealing gasket is provided in each of the two sets of retaining ring grooves. The two sets of first retaining ring grooves are respectively engaged with the middle glass column. The outer ends of the two sets of middle glass columns are respectively connected to the two sets of glass covers through the second column fixing component. The right ends of the two sets of glass covers are respectively provided with inlet and outlet pipes.

[0008] Preferably, the inner end of the connecting ring is provided with a sand core.

[0009] Preferably, the support assembly includes six sets of support legs and six sets of stabilizing plates. The bottom ends of two sets of support columns are respectively connected to three sets of support legs, and the bottom ends of three sets of support legs are respectively connected to stabilizing plates. The top ends of the six sets of stabilizing plates are respectively provided with four sets of mounting through holes, and the six sets of stabilizing plates are respectively provided with four sets of reinforcing ribs.

[0010] Preferably, the transmission assembly includes a servo motor, a first gear, and a second gear. The top of the support is connected to the servo motor, the output end of the servo motor is connected to the first gear, the front end of the first rotating rod is connected to the second gear, and the teeth of the first gear and the second gear mesh.

[0011] Preferably, the angle detection assembly includes a third gear, an encoder, and a fourth gear. The rear end of the rotating rod is connected to the third gear, and the rear end of the rear support frame is provided with a fixing groove. The fixing groove is connected to the encoder assembly, and the output end of the encoder is connected to the fourth gear. The teeth of the third gear and the fourth gear mesh.

[0012] Preferably, the first column fixing assembly includes two sets of first semi-circular retaining rings, two sets of second semi-circular retaining rings, four sets of fixing blocks, and two sets of screws. The top and bottom ends of the connecting ring are respectively connected to the two sets of first semi-circular retaining rings, and the two sets of first semi-circular retaining rings are respectively hinged to the second semi-circular retaining rings. The two sets of middle-section glass columns are respectively fixed to the first and second semi-circular retaining rings. The outer walls of the two sets of middle-section glass columns are respectively provided with first sealing rings. The rear ends of the two sets of first and second semi-circular retaining rings are respectively connected to the fixing blocks. The front ends of the two sets of fixing blocks are respectively provided with first through holes. The two sets of screws pass through the two sets of first through holes, and nuts are respectively provided on the two sets of screws.

[0013] Preferably, the second separation column fixing assembly includes two sets of fixing rings and two sets of fixing caps. The two sets of middle-section glass separation columns are respectively provided with fixing rings, and the outer walls of the two sets of fixing rings are respectively provided with first threads. The two sets of glass caps are respectively provided with sliding fitting fixing caps, and the bottom of the two sets of fixing caps are respectively provided with snap-fit ​​ring grooves. The outer walls of the two sets of snap-fit ​​ring grooves are respectively provided with second threads, and the two sets of first threads are respectively threadedly connected to the second threads.

[0014] Preferably, the inner ends of the two sets of glass covers are respectively provided with a second sealing gasket.

[0015] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0016] 1. A transmission component was added, which uses a servo motor to tilt the column, eliminating the need for manual lifting to tilt it;

[0017] 2. The column is divided into two sections so that it can be disassembled. After the column is tilted at a certain angle, it can be disassembled and then rotated to be vertical. The silicone powder inside will fall out by itself under the action of gravity.

[0018] 3. This utility model, through the design of the first and second column fixing components, makes the middle section of the glass column and glass cover easy to disassemble. This facilitates the removal of residual silica powder after the separation of silica powder impurities by opening the glass cover at the bottom of the glass column. It also facilitates the subsequent cleaning of silica powder adhering to the wall. After cleaning, the disassembled glass column components can be thoroughly cleaned and disinfected. Then, the rotation of the glass column can be precisely controlled by the transmission component and the angle detection component when rotation is required, thus facilitating the practical use of the glass column. In addition, multi-layer sealing gaskets are set in key parts such as connecting rings and glass covers to ensure that no leakage accidents occur under high pressure conditions, ensuring the safety of experimental personnel. Furthermore, the integrated intelligent touch screen, servo motor and other automated control system can accurately control the flow rate, pressure and other parameters of the solenoid valves and pressure gauges in the upper-level device, avoiding safety hazards caused by improper manual adjustment. This facilitates the operation of the equipment and the cleaning of the glass column, thereby enhancing its practicality. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of the connection structure of this utility model;

[0020] Figure 2 This is a schematic diagram of the connection structure between the stabilizing plate and the support leg of this utility model;

[0021] Figure 3 This is a schematic diagram of the connection structure between the support platform and the servo motor of this utility model;

[0022] Figure 4 This is a partially enlarged structural diagram of part A of this utility model;

[0023] Figure 5 This is a partial enlarged structural diagram of the present invention (B).

[0024] The following components are labeled in the attached diagram: 1. Support frame; 2. Platform; 3. Distribution box; 4. Box door; 5. Chamber; 6. Intelligent touch screen; 7. Switch; 8. Wiring main board; 9. First rotating rod; 10. Second rotating plate; 11. Rotating rod; 12. Connecting ring; 13. Middle section glass column; 14. Glass cover; 15. Inlet / outlet pipe; 16. Sand core; 17. Support leg; 18. Stabilizing plate; 19. Reinforcing rib; 20. Servo motor; 21. First gear; 22. Second gear; 23. Third gear; 24. Encoder; 25. Fourth gear; 26. First semi-circular retaining ring; 27. Second semi-circular retaining ring; 28. Fixing block; 29. ​​Screw; 30. Nut; 31. Fixing ring; 32. Fixing cover; 33. First sealing gasket; 34. Second sealing gasket; 35. First sealing ring. Detailed Implementation

[0025] The specific embodiments of this utility model will be further described in detail below with reference to the accompanying drawings and examples. The following examples are used to illustrate this utility model, but are not intended to limit the scope of this utility model.

[0026] like Figures 1 to 5 As shown, this utility model discloses an easy-to-operate glass chromatography column, comprising two sets of support frames 1, a support platform 2, a power distribution box 3, a smart touch screen 6, a power switch 7, a main board 8, a first rotating rod 9, a second rotating rod, a rotating rod 11, a connecting ring 12, two sets of middle glass chromatography columns 13, and two sets of glass covers 14. Support and fixing components are respectively provided at the bottom of the two sets of support frames 1. The front end of the front support frame 1 is connected to the support platform 2, and a rotating component is provided on the support platform 2. The front end of the front support frame 1 is connected to the power distribution box 3, and a hinged door 4 is provided at the front end of the power distribution box 3. A chamber 5 is provided inside the power distribution box 3, and the rear end of the chamber 5 is connected to the smart touch screen 6, the power switch 7, and the main board 8. An angle detection component is provided at the rear end of the rear support frame 1. The bearing seal of the first rotating rod 9 passes through... The front support frame 1, the second rotating plate 10 and the rotating rod 11 are connected. The bearing seal of the rotating rod 11 passes through the rear end of the rear support frame 1. The inner ends of the first rotating plate and the second rotating plate 10 are respectively connected to the connecting ring 12. The top and bottom ends of the connecting ring 12 are provided with the first column fixing assembly. The top and bottom ends of the connecting ring 12 are respectively provided with the first retaining ring groove. The two sets of retaining ring grooves are respectively provided with the first sealing gasket 33. The two sets of first retaining ring grooves are respectively engaged with the middle section glass column 13. The outer ends of the two sets of middle section glass columns 13 are respectively connected to the two sets of glass covers 14 through the second column fixing assembly. The right ends of the two sets of glass covers 14 are respectively provided with inlet and outlet pipes 15. 1. A transmission assembly is added. The column can be tilted by the servo motor in the assembly, so that it does not need to be manually lifted to tilt.

[0027] 2. The column is divided into two sections so that it can be disassembled. After the column is tilted at a certain angle, it can be disassembled and then rotated to be vertical. The silicone powder inside will fall out by itself under the action of gravity.

[0028] 3. This utility model, through the design of the first and second column fixing components, makes the middle section of the glass column and glass cover easy to disassemble. This facilitates the removal of residual silica powder after the separation of silica powder impurities by opening the glass cover at the bottom of the glass column. It also facilitates the subsequent cleaning of silica powder adhering to the wall. After cleaning, the disassembled glass column components can be thoroughly cleaned and disinfected. Then, the rotation of the glass column can be precisely controlled by the transmission component and the angle detection component when rotation is required, thus facilitating the practical use of the glass column. In addition, multi-layer sealing gaskets are set in key parts such as connecting rings and glass covers to ensure that no leakage accidents occur under high pressure conditions, ensuring the safety of experimental personnel. Furthermore, the integrated intelligent touch screen, servo motor and other automated control system can accurately control the flow rate, pressure and other parameters of the solenoid valves and pressure gauges in the upper-level device, avoiding safety hazards caused by improper manual adjustment. This facilitates the operation of the equipment and the cleaning of the glass column, thereby enhancing its practicality.

[0029] As a preferred embodiment of the above, the inner end of the connecting ring 12 is provided with a sand core 16; the sand core can be used to filter impurities in the fluid and improve the mixing of the liquid, thereby enhancing its practicality.

[0030] As a preferred embodiment of the above, the support assembly includes six sets of support legs 17 and six sets of stabilizing plates 18. The bottom ends of the two sets of support columns are respectively connected to three sets of support legs 17, and the bottom ends of the three sets of support legs 17 are respectively connected to the stabilizing plates 18. The top ends of the six sets of stabilizing plates 18 are respectively provided with four sets of mounting through holes, and the six sets of stabilizing plates 18 are respectively provided with four sets of reinforcing ribs 19. The bottom of the two sets of support frames can be supported by the six sets of support legs and the six sets of stabilizing plates, and can be fixed by the six sets of mounting through holes. The ribs on the six sets of stabilizing plates enhance the stability of the bottom of the support legs, thereby enhancing practicality.

[0031] As a preferred embodiment of the above, the transmission assembly includes a servo motor 20, a first gear 21, and a second gear 22. The top of the support 2 is connected to the servo motor 20, the output end of the servo motor 20 is connected to the first gear 21, and the front end of the first rotating rod 9 is connected to the second gear 22. The teeth of the first gear 21 and the second gear 22 mesh. The servo motor can drive the first gear to rotate, and then the second gear meshing with its teeth can drive the first rotating rod and the second rotating rod to rotate the connecting ring and the glass column, thereby facilitating the change of the glass column angle and thus facilitating the disassembly of the glass column, thereby enhancing its practicality.

[0032] As a preferred embodiment of the above, the angle detection component includes a third gear 23, an encoder 24, and a fourth gear 25. The rear end of the rotating rod 11 is connected to the third gear 23, and the rear end of the rear support frame 1 is provided with a fixing groove. The fixing groove is fitted and connected to the encoder 24. The output end of the encoder 24 is connected to the fourth gear 25, and the teeth of the third gear 23 and the fourth gear 25 mesh. When the second rotating rod drives the rotating rod to rotate, the third gear and the fourth gear can rotate, thereby driving the output end of the encoder to rotate, thus accurately counting the rotation angle and enhancing practicality.

[0033] As a preferred embodiment of the above embodiment, the first column fixing assembly includes two sets of first semicircular retaining rings 26, two sets of second semicircular retaining rings 27, four sets of fixing blocks 28, and two sets of screws 29. The top and bottom ends of the connecting ring 12 are respectively connected to the two sets of first semicircular retaining rings 26, and the two sets of first semicircular retaining rings 26 are respectively hinged to the second semicircular retaining rings 27. The two sets of middle-section glass columns 13 are respectively fixed to the first semicircular retaining rings 26 and the second semicircular retaining rings 27. The outer walls of the two sets of middle-section glass columns 13 are respectively provided with first sealing rings 35. The rear ends of the circular retaining ring 26 and the two sets of second semi-circular retaining rings 27 are respectively connected to the fixing block 28. The front ends of the two sets of fixing blocks 28 are respectively provided with first through holes. The two sets of screws 29 pass through the two sets of first through holes respectively, and nuts 30 are provided on the two sets of screws 29 respectively. When it is necessary to clean and replace the middle section glass column, it can be removed first by the two sets of screws and nuts. Then, the two sets of hinged second semi-circular retaining rings can be opened. After that, the middle section glass column that is stuck in the retaining ring groove can be pulled upwards, which facilitates the disassembly of the glass column and thus enhances its practicality.

[0034] As a preferred embodiment of the above embodiment, the second column fixing assembly includes two sets of fixing rings 31 and two sets of fixing covers 32. Fixing rings 31 are respectively provided on the two sets of middle-section glass columns 13. First threads are respectively provided on the outer walls of the two sets of fixing rings 31. Slidingly fitted fixing covers 32 are respectively provided on the two sets of glass covers. A snap-fit ​​ring groove is respectively provided at the bottom of the two sets of fixing covers 32. Second threads are respectively provided on the outer walls of the two sets of snap-fit ​​ring grooves. The two sets of first threads are threadedly connected to the second threads. The middle-section glass column and the glass cover can be tightly attached and disassembled through the two sets of fixing rings and fixing covers, thereby facilitating the separation and cleaning of the glass cover and the middle-section glass column, thus enhancing practicality.

[0035] As a preferred embodiment of the above, the inner ends of the two sets of glass covers are respectively provided with second sealing gaskets 34; the sealing between the middle glass column and the glass cover can be enhanced by the two sets of second sealing gaskets, thereby enhancing practicality.

[0036] This utility model discloses an easy-to-operate glass chromatography column. Its working principle is as follows: During operation, two sets of support frames and the glass chromatography column are first supported by six sets of legs and a stabilizing plate. Then, the two sets of support frames are fixed through four sets of mounting through holes on the stabilizing plate. After all parts are assembled, during normal use, after the silica powder has been processed in the glass chromatography column, the servo motor is started via the intelligent touch screen. The servo motor then drives the first and second gears to rotate, thereby causing the first rotating rod, the second rotating rod, the connecting ring, the glass chromatography column, and the rotating rod to rotate, thus adjusting the angle of the glass chromatography column. Furthermore, as the rotating rod rotates, it drives the third and fourth gears... The glass column is rotated, and rotational data is collected via an encoder to ensure accurate rotation angle. When the glass column is rotated to the appropriate angle, the fixing cover is rotated to disengage it from the fixing ring. The glass cover is then removed. Since the glass column changes angle via a servo motor, some of the silica powder residue on the wall and in the column falls off. When the glass column needs to be cleaned, the two sets of screws and nuts are removed, and the two sets of second semi-circular retaining rings are opened. The middle section of the glass column is then pulled upwards. The middle section of the glass column, the glass cover, and the sand core are then cleaned. Finally, the middle section of the glass column and the glass cover are reassembled as described above.

[0037] The terms “vertical,” “horizontal,” “left,” “right,” and similar expressions used in this article are for illustrative purposes only.

[0038] In this utility model, the terms "first," "second," and "third" do not represent a specific quantity or order, but are merely used to distinguish names.

[0039] The above description is only a preferred embodiment of the present utility model. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the technical principles of the present utility model, and these improvements and modifications should also be considered within the protection scope of the present utility model.

Claims

1. A glass chromatography column which is easy to handle, characterized in that The utility model provides a kind of intelligent power distribution cabinet, including two groups of support frame (1), table (2), distribution box (3), intelligent touch screen (6), electric switch (7), wiring mainboard (8), first rotating rod (9), second rotating rod, rotating rod (11), connecting ring (12) two groups of middle glass column (13) and two groups of glass cover (14), the bottom of two groups of support frame (1) is respectively provided with support fixed component, the front end of front support frame (1) is connected with table (2), and rotating component is provided on table (2), the front end of front support frame (1) is connected with distribution box (3), and the front end of distribution box (3) is provided with hinged door (4), and chamber (5) is provided in distribution box (3), and the rear end of chamber (5) is connected with intelligent touch screen (6), electric switch (7) and wiring mainboard (8), the rear end of rear support frame (1) is provided with angle detection component, first rotating rod (9) bearing seals through front support frame (1), second rotating plate (10) is connected with rotating rod (11), and rotating rod (11) bearing seals passes out the rear end of rear support frame (1), and the inner end of first rotating plate and second rotating plate (10) is respectively connected with connecting ring (12), and the top and bottom of connecting ring (12) are provided with first column fixed component, and the top and bottom of connecting ring (12) are respectively provided with first snap ring groove, and first sealing pad (33) is respectively provided in two groups of first snap ring groove, and two groups of first snap ring groove are respectively connected with middle glass column (13), and the outer end of two groups of middle glass column (13) is connected with two groups of glass cover (14) by second column fixed component, and the right end of two groups of glass cover (14) is respectively provided with inlet and outlet pipe (15).

2. A glass chromatography column for ease of operation as claimed in claim 1 wherein, The inner end of the connecting ring (12) is provided with a sand core (16).

3. A glass chromatography column for ease of operation as claimed in claim 2 wherein, The support assembly includes six groups of legs (17), six groups of stable plates (18), the bottom of the two groups of support columns is respectively connected with the three groups of legs (17), the bottom of the three groups of legs (17) is respectively connected with the stable plates (18), the top of the six groups of stable plates (18) is respectively provided with four groups of mounting through holes, and the six groups of stable plates (18) are respectively provided with four groups of reinforcing ribs (19).

4. A glass chromatography column for ease of operation as claimed in claim 3 wherein, The transmission assembly includes a servo motor (20), a first gear (21), and a second gear (22), the top of the table (2) is connected with the servo motor (20), the output end of the servo motor (20) is connected with the first gear (21), the front end of the first rotating rod (9) is connected with the second gear (22), and the first gear (21) and the second gear (22) are in meshing engagement.

5. A glass chromatography column for ease of operation as claimed in claim 4 wherein, The angle detection component includes a third gear (23), an encoder (24), and a fourth gear (25), the rear end of the rotating rod (11) is connected with the third gear (23), the rear end of the rear support frame (1) is provided with a fixing groove, the fixing groove is connected with the encoder (24), the output end of the encoder (24) is connected with the fourth gear (25), and the third gear (23) and the fourth gear (25) are in meshing engagement.

6. A glass chromatography column for ease of operation as claimed in claim 5 wherein, The first column fixed assembly includes two groups of first semicircle clamping rings (26), two groups of second semicircle clamping rings (27), four groups of fixed blocks (28) and two groups of screws (29), the top end and the bottom end of the connecting ring (12) are connected with the two groups of first semicircle clamping rings (26), the two groups of first semicircle clamping rings (26) are hinged with the second semicircle clamping rings (27), the two groups of middle glass columns (13) are clamped and fixed with the first semicircle clamping rings (26) and the second semicircle clamping rings (27), the outer wall of the two groups of middle glass columns (13) is respectively provided with a first sealing ring (35), the rear end of the two groups of first semicircle clamping rings (26) and the two groups of second semicircle clamping rings (27) is connected with the fixed block (28), the front end of the two groups of fixed blocks (28) is respectively provided with a first through hole, the two groups of screws (29) pass through the two groups of first through holes respectively, and the two groups of screws (29) are respectively provided with a nut (30).

7. A glass chromatography column for ease of operation as claimed in claim 6 wherein, The second column fixed assembly includes two groups of fixed rings (31) and two groups of fixed covers (32), the two groups of middle glass columns (13) are respectively provided with the fixed ring (31), the outer wall of the two groups of fixed rings (31) is respectively provided with a first thread, the two groups of glass covers are respectively provided with the slidingly sleeved fixed cover (32), the bottom of the two groups of fixed covers (32) is respectively provided with a clamping ring groove, the outer wall of the two groups of clamping ring grooves is respectively provided with a second thread, and the two groups of first threads are respectively threadedly connected with the second threads.

8. A glass chromatography column for ease of operation as claimed in claim 7, wherein, The inner end of the two groups of glass covers is respectively provided with a second sealing gasket (34).

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