Constant-temperature heating device for virus microbiological detection

Abstract

The utility model relates to the technical field of virus microbiological detection, in particular to a virus microbiological detection constant-temperature heating device which comprises a shell, ground feet and an upper cover, ground feet are arranged at the bottom of the shell, and an upper cover is arranged at the top of the shell through a torsional spring; the device further comprises an upper heating assembly and a lower heating assembly, the upper heating assembly is arranged on the upper cover, the lower heating assembly is arranged in the shell, and the upper portion and the lower portion of a sample are heated, kept at the constant temperature and cooled at the same time through the upper heating assembly and the lower heating assembly. The utility model solves the problems that the detection period is prolonged, the detection speed is slow, the detection accuracy and the detection efficiency are reduced, and the occupied space is larger in the existing virus microorganism detection process due to longer time consumption in the heating process; in the detection process of virus microorganisms, the temperature rising speed is high, the detection period is short, the detection accuracy and the detection efficiency are greatly improved, and the occupied space is reduced.

Description

Technical Field

[0001] This utility model relates to the field of virus and microbial detection technology, and in particular to a constant temperature heating device for virus and microbial detection. Background Technology

[0002] With the rapid development of modern biotechnology, viral and microbial detection has gradually become a key link in the fields of medicine, public health, and scientific research. Among the many viral detection methods, PCR technology is widely used due to its high sensitivity and high specificity. However, traditional PCR viral detection usually requires the reaction to be carried out at a constant temperature of 65℃-70℃, which places high demands on the temperature control of the experimental environment and usually relies on heating equipment such as water baths to provide a constant temperature environment.

[0003] In virus testing, especially in scenarios involving large-scale samples or urgent testing, time efficiency and accuracy are crucial. However, the heating process of traditional water baths takes a long time, which can lead to a longer testing cycle and affect the timeliness and accuracy of test results. This is particularly true in emergency response and rapid diagnosis situations, where traditional water baths cannot meet the needs of rapid detection of viruses and microorganisms, thus reducing testing efficiency. Furthermore, traditional water bath equipment is bulky and occupies a lot of space.

[0004] Therefore, this utility model provides a constant temperature heating device for virus and microorganism detection. Utility Model Content

[0005] The purpose of this invention is to propose a constant-temperature heating device for virus and microorganism detection, which solves the problem that existing virus and microorganism detection methods have long heating times, resulting in extended detection cycles, slow detection speeds, reduced detection accuracy and efficiency, and large footprints. This invention achieves rapid heating and short detection cycles for virus and microorganism detection, greatly improving detection accuracy and efficiency while reducing footprint.

[0006] To achieve the above objectives, the present invention adopts the following technical solution:

[0007] A constant temperature heating device for detecting viruses and microorganisms includes a housing, feet, and a top cover; the bottom of the housing is provided with feet, and the top of the housing is provided with a top cover via a torsion spring;

[0008] It also includes an upper heating component and a lower heating component. The upper heating component is disposed on the upper cover, and the lower heating component is disposed inside the outer shell. The upper heating component and the lower heating component simultaneously heat, maintain and cool the upper and lower parts of the sample.

[0009] Preferably, the upper heating assembly includes a heat cover, a first heating film, and a first temperature sensor; the heat cover is disposed inside the upper cover, the first heating film is disposed on the side of the heat cover close to the upper cover, the first temperature sensor is disposed on the side of the heat cover, and the first heating film and the first temperature sensor are not located on the same side.

[0010] Preferably, the lower heating assembly includes a heating tank shell, a sample placement slot, a heat-conducting shell, a second heating film, and a second temperature sensor;

[0011] The outer shell is provided with a heat sink shell, the inside of the heat sink shell is provided with a sample placement slot, the bottom of the sample placement slot is provided with a heat-conducting shell, a second heating film is provided on any side of the heat-conducting shell, and a second temperature sensor is provided on the heat-conducting shell, and the second temperature sensor is located on the same side of the second heating film.

[0012] Preferably, the hot tub shell is surrounded by a circumferential anti-scalding shell.

[0013] Preferably, the first heating film and the second heating film are PI heating films.

[0014] Preferably, the internal resistance alloy of the first heating film is a uniform U-shaped continuous structure, and the internal resistance alloy of the second heating film is a U-shaped continuous structure with dense ends and sparse middle.

[0015] Preferably, the sample placement slot has a conical structure.

[0016] Preferably, the housing is provided with a plurality of cooling fans, and the plurality of cooling fans are respectively located on the left side, right side and bottom of the housing.

[0017] Preferably, a device switch and a power interface are respectively provided on one side of the housing, and a display screen is provided on the top of the housing.

[0018] Preferably, the upper cover is provided with a press-lock buckle.

[0019] The beneficial effects of this utility model are:

[0020] 1. This utility model has an upper heating component and a lower heating component on the outer shell. Through the cooperation of the heat cover on the upper heating component and the heat tank shell, the first heating film and the second heating film are heated, kept constant and cooled at the same time, and reach the set temperature in a short time. This enables rapid detection of viruses and microorganisms, shortens the detection cycle and greatly improves the accuracy and efficiency of detection.

[0021] 2. This utility model reduces the overall size of the device by providing an upper heating component and a lower heating component on the outer shell, making the overall detection device occupy less space. Eight sets of samples can be placed in the sample placement slot inside the lower heating component, and the temperature between each set of samples is uniform and consistent through the second heating film, with the temperature difference controlled within ±0.5℃. Attached Figure Description

[0022] Figure 1 This is a three-dimensional structural diagram of the present invention.

[0023] Figure 2 This is a three-dimensional structural diagram of the heat cover of this utility model.

[0024] Figure 3 This is a three-dimensional structural diagram of the heat sink shell, heat-conducting shell, anti-scalding shell, and sample placement slot of this utility model.

[0025] Figure 4 This is a flowchart of the present invention.

[0026] Figure 5 This is a physical image of the present invention.

[0027] In the diagram: 1. Outer shell; 11. Cooling fan; 12. Device switch; 13. Power interface; 14. Display screen; 2. Foot; 3. Top cover; 31. Press-lock buckle; 4. Torsion spring; 5. Upper heating assembly; 51. Heating cover; 52. First heating film; 53. First temperature sensor; 6. Lower heating assembly; 61. Heating tank shell; 62. Sample placement slot; 63. Heat-conducting shell; 64. Second heating film; 65. Second temperature sensor; 67. Anti-scalding shell. Detailed Implementation

[0028] The method of using this utility model will be further described below with reference to the accompanying drawings and specific embodiments.

[0029] like Figures 1 to 5 As shown, a constant temperature heating device for detecting viruses and microorganisms includes a shell 1, a foot 2, and a top cover 3; the bottom of the shell 1 is provided with the foot 2, and the top of the shell 1 is provided with the top cover 3 via a torsion spring 4; the shell 1 is hinged to the top cover 3 via the torsion spring 4.

[0030] It also includes an upper heating component 5 and a lower heating component 6. The upper heating component 5 is disposed on the upper cover 3, and the lower heating component 6 is disposed inside the outer shell 1. The upper heating component 5 and the lower heating component 6 simultaneously heat, maintain and cool the sample from the top and bottom.

[0031] The upper heating assembly 5 includes a heat cover 51, a first heating film 52, and a first temperature sensor 53. The heat cover 51 is disposed inside the upper cover 3, the first heating film 52 is disposed on the side of the heat cover 51 close to the upper cover 3, and the first temperature sensor 53 is disposed on one side of the heat cover 51, and the first heating film 52 and the first temperature sensor 53 are not located on the same side.

[0032] The heat cover 51 is made of 6061 aluminum alloy with an anodized black finish. The primary stabilizing sensor is a PT100 temperature sensor.

[0033] The lower heating assembly 6 includes a heating tank shell 61, a sample placement slot 62, a heat-conducting shell 63, a second heating film 64, and a second temperature sensor 65.

[0034] The outer shell 1 is provided with a heat sink shell 61, the inside of the heat sink shell 61 is provided with a sample placement slot 62, the bottom of the sample placement slot 62 is provided with a heat-conducting shell 63, a second heating film 64 is provided on any side of the heat-conducting shell 63, and a second temperature sensor 65 is provided on the heat-conducting shell 63, and the second temperature sensor 65 is located on the same side of the second heating film 64.

[0035] The second heating film 64 is connected to the heat-conducting shell 63 by a high-temperature adhesive backing. The heat-conducting shell 63 is connected to the anti-scalding shell 67 by screws. The heat groove shell 61 is sealed to the inside of the heat-conducting shell 63 by thermally conductive sealing silicone.

[0036] The hot slot shell 61 is made of 6061 aluminum alloy with anodized black finish.

[0037] The heat sink shell 61 is surrounded by a ring of anti-scalding shells 67. The anti-scalding shells 67 are made of nylon.

[0038] The first heating film 52 and the second heating film 64 are PI heating films.

[0039] PI heating film is a yellow transparent metal flexible electric heating film with a sandwich structure. The upper and lower insulating layers are polyimide films, which have the characteristics of high insulation strength, excellent dielectric strength and high thermal conductivity. The heating element is made of precision resistance alloy, which has strong resistance stability and uniform heating. The alloy pattern is U-shaped, which achieves higher thermal efficiency within a limited volume.

[0040] By heating the PI heating film, the entire heating cover 51 is heated, and the upper part of the virus sample is heated through the heating cover 51. The heating process is monitored by the PT100 to achieve precise temperature control.

[0041] The first heating film 52 has a uniform U-shaped continuous resistance alloy structure, while the second heating film 64 has a U-shaped continuous resistance alloy structure with denser ends and sparser middle. The denser ends and sparser middle of the resistance alloy in the second heating film 64 is to avoid the temperature difference between the eight sample placement slots 62 being too large due to external influences on the temperature at both ends.

[0042] The sample placement slot 62 has a conical structure. The conical structure of the sample placement slot 62 incorporates eight sample slots, compatible with commonly used PCR eight-tube sets for viral and microbial detection.

[0043] The housing 1 is equipped with a plurality of cooling fans 11, which are located on the left, right and bottom sides of the housing 1, respectively. The cooling fans 11 are connected to the housing 1 by screws.

[0044] The sample placement temperature is rapidly reduced by powering the device. The two cooling fans 11 located on the left and right sides of the outer casing 1 are only turned on when the device starts the cooling program, while the cooling fan 11 located at the bottom of the outer casing 1 runs continuously when the device is powered on, ensuring that the temperature near the main chip is moderate and protecting the device's control circuit.

[0045] A device switch 12 and a power interface 13 are respectively provided on one side of the housing 1, and a display screen 14 is provided on the top of the housing 1.

[0046] The power interface 13 is connected to the housing 1 by screws, the device switch 12 is connected to the housing 1 by a clip on the side of the switch, and the display screen 14 is connected to the housing 1 by screws.

[0047] The display control system consists of a 7-inch LCD touch screen and a main control chip. The target heating temperature and holding time can be set on the 7-inch LCD touch screen. After the setting is completed, the device starts heating, and the real-time temperature of the sample can be seen on the screen. When the device reaches the target temperature and holding time, the device starts cooling.

[0048] It features a temperature display and sensor value reading interface, and a reserved Type-C communication port, enabling data exchange with other devices for automated testing. Additionally, it includes an interface for detection devices, allowing for automated testing of viruses and microorganisms when paired with different sensors.

[0049] The upper cover 3 is provided with a press-lock buckle 31. The upper cover 3 and the outer shell 1 can be locked by pressing the press-lock buckle 31.

[0050] It should be noted that this utility model also includes the use of existing PID temperature control technology, which dynamically adjusts the current of the PI heating film of the hot tub shell 61 and the hot cover 51 through PID parameters, thereby controlling the temperature change of the device. Simultaneously, a communication module is integrated into the entire control system. The communication module adopts both wired and wireless communication methods, such as existing technologies like RS232, RS485, WIFI, and 4G communication, to transmit the collected data to the control system via touchscreen display, mobile phone SMS, and remote monitoring center. All the above-mentioned functional modules integrated into the control system can be implemented using existing technologies. The device can also integrate an alarm device, such as an audible and visual alarm. Through the cooperation of the signal transmission panel and the alarm device, data processing and alarm warnings can be achieved, real-time data monitoring can be performed, and alarm information can be sent promptly when the total nitrogen content in the water reaches the warning value, reminding operators to take appropriate action, effectively ensuring the safety and stability of water quality.

[0051] To conduct actual tests on this invention, a PT temperature sensor was placed in each of the eight samples, and different temperature values ​​were set. After the temperature was reached, the different temperature values ​​of the eight samples were tested. The test results are shown in Table 1.

[0052] Table 1. Actual temperature values ​​at different set temperatures in the 8 sample cells tested.

[0053] Set temperature #1 Temperature Temperature #2 Temperature #3 Temperature #4 Temperature #5 Temperature #6 Temperature #7 Temperature #8 40℃ 39.8℃ 39.7℃ 40.0℃ 40.0℃ 40.1℃ 40.0℃ 40.1℃ 39.9℃ 50℃ 50.3℃ 50.1℃ 50.1℃ 50.2℃ 50.2℃ 50.2℃ 50.1℃ 50.2℃ 60℃ 59.7℃ 59.7℃ 59.9℃ 60.0℃ 60.0℃ 60.2℃ 60.1℃ 60.0℃ 70℃ 70.1℃ 70.2℃ 70.4℃ 70.4℃ 70.3℃ 70.2℃ 70.1℃ 70.0℃ 80℃ 80.0℃ 80.2℃ 80.1℃ 80.1℃ 80.1℃ 80.2℃ 80.1℃ 80.0℃ 90℃ 90.2℃ 90.2℃ 90.2℃ 90.4℃ 90.3℃ 90.2℃ 90.2℃ 90.0℃

[0054] During operation, firstly, the target temperature and maintenance time are set on the display screen 14. Then, the sample to be tested is placed in the sample placement slot 62, and the upper cover 3 is closed. The upper cover 3, along with the hot cover 51, is locked to the outer shell 1 by pressing the latch 31. After clicking the start heating button, the main chip of the device controls the power supply pulses of the first heating film 52 and the hot cover 51 through the PID algorithm. When the first temperature sensor 53 and the second temperature sensor 65 inside the device reach the set temperature, the hot tank shell 61 and the hot cover 51 begin to maintain the current temperature until the required maintenance time is reached. Then, the cooling fan 11 is started to dissipate heat. When the second temperature sensor 65 on the hot tank shell 61 is detected to have reached the preset heat dissipation temperature, the cooling fan 11 is turned off, and the display screen 14 shows that the reaction is complete and the operator is ready to conduct further testing.

[0055] Finally, it should be noted that the above are merely preferred embodiments of the present utility model and are not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. However, any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A virus microorganism detection constant temperature heating device, comprising a shell (1), a foot (2) and an upper cover (3); the bottom of the shell (1) is provided with the foot (2), and the top of the shell (1) is provided with the upper cover (3) through a torsional spring (4); characterized in that further comprising an upper heating assembly (5) and a lower heating assembly (6), the upper heating assembly (5) is arranged on the upper cover (3), and the lower heating assembly (6) is arranged inside the shell (1) and simultaneously heats, constant temperature and cools the upper and lower parts of the sample through the upper heating assembly (5) and the lower heating assembly (6).

2. The constant temperature heating device for detecting viral microorganisms according to claim 1, characterized in that: The upper heating assembly (5) comprises a heat cover (51), a first heating film (52) and a first temperature sensor (53); the heat cover (51) is arranged on the inner side of the upper cover (3), the first heating film (52) is arranged on the side of the heat cover (51) close to the upper cover (3), and the first temperature sensor (53) is arranged on one side of the heat cover (51); The lower heating assembly (6) comprises a heat tank shell (61), a sample placing groove (62), a heat conduction shell (63), a second heating film (64) and a second temperature sensor (65); The shell (1) is provided with the heat tank shell (61), the inside of the heat tank shell (61) is provided with the sample placing groove (62), the bottom of the sample placing groove (62) is provided with the heat conduction shell (63), one side of the heat conduction shell (63) is provided with the second heating film (64), and the heat conduction shell (63) is provided with the second temperature sensor (65).

3. The constant temperature heating device for detecting viral microorganisms according to claim 2, characterized in that: The heat tank shell (61) is annularly arranged with an anti-scald shell (67) around.

4. The constant temperature heating device for detecting viral microorganisms according to claim 2, characterized in that: The first heating film (52) and the second heating film (64) are PI heating films.

5. The constant temperature heating device for detecting viral microorganisms according to claim 2, characterized in that: The internal resistance alloy of the first heating film (52) is a uniform U-shaped continuous structure, and the internal resistance alloy of the second heating film (64) is a U-shaped continuous structure with dense ends and sparse middle.

6. The constant temperature heating device for detecting viral microorganisms according to claim 2, characterized in that: The sample placing groove (62) is a conical structure.

7. The constant temperature heating device for detecting viral microorganisms according to claim 1, characterized in that: A plurality of heat dissipation fans (11) are arranged inside the shell (1), and the plurality of heat dissipation fans (11) are respectively located on the left side, the right side and the bottom of the shell (1).

8. The constant temperature heating device for detecting viral microorganisms according to claim 1, characterized in that: A device switch (12) and a power supply interface (13) are arranged on one side of the shell (1), and a display screen (14) is arranged on the top of the shell (1).

9. The constant temperature heating device for detecting viral microorganisms according to claim 1, characterized in that: A pressing lock buckle (31) is arranged on the upper cover (3).

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