Special pore plate accessory for magnetic field intervention

Abstract

The utility model relates to the field of medical instruments, and discloses a special pore plate accessory for magnetic field intervention, which comprises an outer shell, a magnetic intervention pore plate, a fixed magnetic field mechanism and a magnetic force adjusting mechanism, wherein the fixed magnetic field mechanism comprises magnet grooves uniformly formed in the magnetic intervention hole plate, and magnet sheets are fixedly mounted in the magnet grooves; the magnetic adjusting mechanism comprises a magnetic adjusting assembly and a magnetic stabilizing assembly which are arranged on the lower surface of the magnetic intervention hole plate; according to the pore plate accessory special for magnetic field intervention, the magnetic field fixing mechanism and the magnetic force adjusting mechanism are adopted, the problems that in the prior art, the magnetic field intensity is uneven, a magnet cannot be adjusted after being fixed, and the magnet is difficult to disinfect are effectively solved, and the convenience of an experiment and the stability of a result are improved.

Description

Technical Field

[0001] This utility model relates to the field of medical devices, and in particular to a special orifice plate accessory for magnetic field intervention. Background Technology

[0002] In cell culture and magnetic field intervention experiments, researchers typically place magnets at the bottom or top of culture plates to observe the effects of magnetic fields on cell growth and behavior. However, some problems exist with current techniques:

[0003] First, existing magnetic field intervention methods rely on separately purchased magnets, and the magnetic field strength of different magnets may vary, resulting in inconsistent magnetic field strength in experiments. Furthermore, the size of existing magnets is usually not a perfect match for the chambers of culture plates, causing the cells in the plates to be exposed to an uneven magnetic field environment, thus affecting the accuracy of experimental results. In addition, bare magnets are difficult to sterilize thoroughly during experiments, which may increase the risk of contamination in cell culture.

[0004] Secondly, different magnetic fields may be required during the experiment. However, in the existing technology, the magnet needs to be sealed and fixed. Once installed, the magnet cannot be replaced, which makes it difficult to meet the needs of different experimental conditions and limits the applicability of the accessories.

[0005] Therefore, there is an urgent need to design a special orifice plate accessory for magnetic field intervention that can solve the above technical problems. Utility Model Content

[0006] In view of the problems mentioned in the background art, the purpose of this utility model is to provide a special orifice plate accessory for magnetic field intervention, so as to solve the problems mentioned in the background art.

[0007] To achieve the above objectives, this utility model mainly provides the following technical solutions:

[0008] A magnetic field interference orifice plate accessory includes a housing and a magnetic interference orifice plate, and further includes:

[0009] Fixed magnetic field mechanism and magnetic force adjustment mechanism; wherein:

[0010] The fixed magnetic field mechanism includes magnet slots uniformly opened inside the magnetic interference perforated plate, and magnet plates are fixedly installed inside the magnet slots;

[0011] The magnetic force adjustment mechanism includes a magnetic force adjustment component and a magnetic force stabilization component located on the lower surface of the magnetic intervention orifice plate.

[0012] Furthermore, the upper surface of the outer shell is provided with a perforated plate limiting groove, the interior is hollow and a magnetic adjustment groove is provided, and a screw hole is provided through the center of the lower surface, with an internal thread on the inner ring of the screw hole;

[0013] The magnetic interference plate is movably placed inside the magnetic force adjustment groove, and its upper surface is tightly attached to the top wall of the magnetic force adjustment groove.

[0014] Furthermore, the magnetic force adjustment component includes a slot located in the center of the lower surface of the magnetic interference hole plate, a movably mounted clip is installed in the slot, a screw is fixedly connected to the lower surface of the clip, the screw has an external thread on its surface, the lower end of the screw passes through the screw hole and is threadedly connected to it, and a knob head is provided at its bottom end.

[0015] Furthermore, the magnetic stabilizing component includes multiple reset springs, which are respectively located at the four corners of the lower surface of the magnetic interference hole plate, and the other end of the reset spring is fixedly connected to the bottom wall of the magnetic adjustment groove.

[0016] Furthermore, the magnetic intervention perforation plate has three specifications: 6-hole plate, 12-hole plate and 24-hole plate. The diameter and height of the magnetic slots and magnetic sheets in the same magnetic intervention perforation plate are consistent.

[0017] The location and number of the magnet slots correspond longitudinally to the well plates of the cultured cells.

[0018] Furthermore, height-increasing feet are provided at the four corners of the bottom wall of the outer shell.

[0019] Furthermore, the outer shell and the magnetic interference plate are both made of transparent and corrosion-resistant materials; the reset spring and the screw are both made of corrosion-resistant metal materials.

[0020] Compared with the prior art, the beneficial effects of this utility model are mainly reflected in:

[0021] Firstly, compared to existing methods that directly adhere magnets to the bottom or top of the orifice plate, this invention provides a magnetic field intervention orifice plate accessory that employs a fixed magnetic field mechanism. By uniformly arranging magnet slots inside the magnetic intervention orifice plate and fixing magnet pieces within these slots, the consistent arrangement of the magnets is ensured, thereby effectively improving the uniformity of the magnetic field and the reliability of experimental data.

[0022] Secondly, compared to existing magnets that cannot be replaced or adjusted after installation, it is difficult to flexibly adjust the magnetic field strength during experiments. To solve this problem, this utility model provides a magnetic field intervention well plate accessory that adopts a magnetic adjustment mechanism. By setting an adjustable magnetic adjustment component below the magnetic intervention well plate, the height of the magnet can be stably raised or lowered, thereby controlling the intensity of the magnetic field on the cells and meeting the magnetic field requirements under different experimental conditions. This effectively improves the flexibility of the experiment and the applicability of the accessory.

[0023] The above description is only an overview of the technical solution of this utility model. In order to clearly understand the technical means of this utility model and to implement it in accordance with the contents of the specification, the preferred embodiments of this utility model are described in detail below with reference to the accompanying drawings. Attached Figure Description

[0024] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0025] Figure 1 This is a perspective view of the orifice plate accessory for magnetic field intervention according to this utility model;

[0026] Figure 2 This is a structural diagram of the orifice plate accessory for magnetic field intervention according to this utility model;

[0027] Figure 3 An exploded view of the orifice plate accessory for magnetic field intervention according to this utility model;

[0028] Figure 4 The structure of the magnetic interference perforated plate of this utility model Figure 1 (6-hole plate specifications);

[0029] Figure 5 The structure of the magnetic interference perforated plate of this utility model Figure 2 (12-hole plate specifications);

[0030] Figure 6 The structure of the magnetic interference perforated plate of this utility model Figure 3 (24-hole plate specifications);

[0031] Explanation of reference numerals in the attached figures:

[0032] 1. Outer shell; 2. Fixed magnetic field mechanism; 3. Magnetic force adjustment mechanism; 4. Magnetic interference perforation plate;

[0033] 11. Perforated plate limiting groove; 12. Magnetic adjustment groove; 13. Screw hole; 14. Internal thread; 15. Heightening foot pad;

[0034] 21. Magnetic groove; 22. Magnetic sheet;

[0035] 31. Magnetic force adjustment component; 32. Magnetic force stabilization component;

[0036] 311. Slot; 312. Clip; 313. Screw; 314. External thread; 315. Knob head; 321. Return spring; Detailed Implementation

[0037] The present application will now be described in further detail with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the relevant utility model and not intended to limit the scope of the utility model. Furthermore, it should be noted that, for ease of description, only the parts relevant to the utility model are shown in the accompanying drawings.

[0038] like Figure 1-6 As shown, a magnetic field intervention orifice plate accessory of this utility model includes a housing 1 and a magnetic intervention orifice plate 4, and further includes:

[0039] Fixed magnetic field mechanism 2 and magnetic force adjustment mechanism 3; wherein:

[0040] The fixed magnetic field mechanism 2 includes magnet slots 21 uniformly arranged inside the magnetic intervention well plate 4. The uniform arrangement of the magnet slots 21 ensures that the magnet pieces 22 are reasonably distributed inside the magnetic intervention well plate 4, so that the magnetic field strength of each culture well on the culture cell plate is consistent, reducing experimental errors caused by uneven magnetic field. The magnet pieces 22 are fixedly installed in the magnet slots 21 to prevent the magnet pieces 22 from moving or tilting due to external vibration or operation during the experiment, thereby ensuring the stability of the magnetic field.

[0041] The magnetic force adjustment mechanism 3 includes a magnetic force adjustment component 31 and a magnetic force stabilization component 32 disposed on the lower surface of the magnetic intervention plate 4. The magnetic force adjustment component 31 is used to control the height of the magnetic intervention plate 4 so as to adjust the magnetic field strength according to experimental requirements, which solves the problem that the magnetic field cannot be adjusted after the magnet is encapsulated and improves the flexibility of the experiment. The magnetic force stabilization component 32 is used to maintain the balance of the magnetic intervention plate 4 and prevent the plate from tilting or shaking when adjusting the magnetic force, thereby ensuring the stability of the magnetic field environment during the experiment.

[0042] like Figure 1 , 2 As shown, in this embodiment, a well plate limiting groove 11 is opened on the upper surface of the outer shell 1. The well plate limiting groove 11 is used to precisely limit the placement position of the well plate for culturing cells, ensuring that the longitudinal position of its chambers and the magnetic plate 22 can correspond one-to-one, preventing the well plate for culturing cells from shifting or tilting due to external forces during the experiment, thereby ensuring the stability and uniformity of the magnetic field. A magnetic force adjustment groove 12 is opened in the hollow interior. The magnetic force adjustment groove 12 provides upper and lower movement space for the magnetic intervention well plate 4, so that the magnetic force adjustment component 31 can freely adjust the height of the magnetic plate 22, thereby changing the magnetic field strength experienced by the cells during the experiment. A screw hole 13 is opened through the center of the lower surface. The screw hole 13 provides a channel for fixing the magnetic force adjustment component 31, thereby realizing the precise adjustment of the height of the magnetic plate 22. The inner ring of the screw hole 13 is provided with an internal thread 14. The internal thread 14 ensures that the position of the magnetic plate 22 can be stably adjusted and fixed when the screw 313 is rotated, thereby ensuring the stability of the experimental process.

[0043] The magnetic intervention plate 4 is movably placed inside the magnetic adjustment groove 12, with its upper surface tightly attached to the top wall of the magnetic adjustment groove 12. This tight fit with the top wall ensures that the magnet 22 maintains a minimum initial distance from the culture well, thereby providing a stronger magnetic field. At the same time, the tight fit also ensures the parallel movement of the magnetic intervention plate 4 during the adjustment process. That is, when the plate is moved up and down to adjust the height, it will not tilt or shift, thus ensuring that the cells in each well chamber are always subjected to a uniform magnetic field strength, improving the reliability of the experiment.

[0044] like Figure 2 , 3 As shown, in this embodiment, the magnetic force adjustment component 31 includes a slot 311 located in the center of the lower surface of the magnetic interference perforation plate 4. The slot 311 is a circular slot used to accommodate a circular clip. A clip 312 is movably installed in the slot 311. The clip 312 is also a circular clip, ensuring that the clip 312 can rotate stably within the slot 311 and restricting its vertical movement. A screw 313 is fixedly connected to the lower surface of the clip 312. The screw 313 serves as a transmission mechanism to ensure the controllability of the magnetic field strength during the experiment. The surface of the screw 313 is provided with an external thread 314. The lower end of the screw 313 passes through the screw hole 13 and is threadedly connected to it. The external thread 314 engages with the internal thread 14 of the screw hole 13. The screw 313 is stably fixed to the bottom of the perforation plate. The height of the magnet 22 can be adjusted by the spiral motion, thereby controlling the height of the magnetic interference perforation plate 4. A knob head 315 is provided at its bottom end, providing a manual adjustment interface so that the experimenter can easily adjust the magnetic field strength according to the experimental requirements.

[0045] like Figure 2 , 3 As shown, in this embodiment, the magnetic stabilizing component 32 includes multiple reset springs 321, which are respectively disposed at the four corners of the lower surface of the magnetic intervention hole plate 4. The other end of the reset spring 321 is fixedly connected to the bottom wall of the magnetic adjustment groove 12. The reset spring 321 ensures that the magnetic intervention hole plate 4 is continuously supported by the elastic force of the reset spring 321, avoiding the tilting or positional displacement of the hole plate caused by uneven force when adjusting the magnetic adjustment component 31. At the same time, the magnetic intervention hole plate 4 can still maintain balance after the height is adjusted, ensuring the uniformity of the magnetic field during the experiment.

[0046] like Figure 4 , 5As shown in Figures 6 and 6, in this embodiment, the magnetic intervention plate 4 has three specifications: 6-well plate, 12-well plate, and 24-well plate. Different specifications of plate are suitable for experimental needs of different scales. The adaptability of the three specifications of cell culture plate improves the adaptability of this device. The diameter and height of the magnetic groove 21 and the magnetic piece 22 in the same magnetic intervention plate 4 are consistent, ensuring that the magnetic field strength in all the holes in the same magnetic intervention plate 4 is consistent, avoiding uneven magnetic field distribution due to different sizes of magnetic pieces 22, thereby improving the reliability of experimental data.

[0047] The location and number of the magnet slots 21 correspond longitudinally to the well chambers of the cultured cells, ensuring that the magnets 22 can accurately act on the target cell area, making the magnetic field intensity on the cells uniform and avoiding experimental errors caused by the positional deviation of the magnets 22.

[0048] like Figure 2 , 3 As shown, in this embodiment, heightening feet 15 are provided at the four corners of the bottom wall of the outer shell 1. The heightening feet 15 not only improve the stability of the outer shell 1 and prevent the perforated plate from tilting due to uneven contact surfaces, but also provide operating space for the screw 313 to rotate downwards, thereby reducing the magnetic force intensity.

[0049] In this embodiment, both the outer shell 1 and the magnetic interference aperture plate 4 are made of transparent and corrosion-resistant materials. The transparent material allows the experimenter to directly observe the height and balance of the magnetic interference aperture plate 4 during the magnetic field intervention process, improving the convenience of the experiment. At the same time, the corrosion resistance ensures that the device is not affected by chemical reagents during long-term use, improving its durability. The reset spring 321 and the screw 313 are both made of corrosion-resistant metal materials. The corrosion-resistant metal ensures that the spring and screw 313 are not prone to rusting in high humidity, strong magnetic field or chemical reagent environments, ensuring their long-term stable rebound performance and adjustment accuracy.

[0050] The working principle and usage process of this technical solution are as follows: During use, the experimenter first selects a well plate accessory with appropriate specifications for the magnetic intervention well plate 4 according to the experimental requirements, places the well plate containing cultured cells into the well plate limiting groove 11, and after ensuring stable placement, observes whether the longitudinal positions of the well plate chambers and the magnetic plates 22 in the magnetic intervention well plate 4 correspond one-to-one to ensure the uniformity of the magnetic field effect. Next, the experimenter adjusts the height of the screw 313 by rotating the knob head 315, thereby adjusting the distance between the magnetic plates 22 and the well plate chambers to achieve precise control of the magnetic field strength. At the same time, the reset spring 321 automatically provides support force to ensure that the well plate is in a stable state, avoiding the displacement or tilting of the magnetic intervention well plate 4 from interfering with the experimental results. Finally, after the experiment, the experimenter can disassemble the well plate containing cultured cells for cleaning and disinfection to ensure a sterile environment for the next use. The design of this device effectively solves the problems of uneven magnetic field strength, inability to adjust the magnet after fixing, and difficulty in disinfecting the magnet in the existing technology, improving the convenience of the experiment and the stability of the results.

[0051] The present invention has been further described above with reference to the embodiments, but the present invention is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of the present invention.

Claims

1. A magnetic field intervention dedicated well plate assembly comprising an outer housing (1) and a magnetic intervention well plate (4), characterized in that: Also include: Fixed magnetic field mechanism (2) and magnetic force adjustment mechanism (3); wherein: Fixed magnetic field mechanism (2) includes a uniform magnetic slot (21) in the magnetic intervention hole plate (4) inside, the magnetic slot (21) is fixedly installed with magnet piece (22); Magnetic force adjustment mechanism (3) includes magnetic force adjustment assembly (31) and magnetic force stability assembly (32) arranged on the lower surface of magnetic intervention hole plate (4).

2. A magnetic field intervention dedicated wellbore assembly according to claim 1, characterized in that: The upper surface of the outer shell (1) is provided with a hole plate limiting groove (11), a hollow magnetic force adjusting groove (12) is provided inside, a screw hole (13) is provided through the center of the lower surface, and an internal thread (14) is provided on the inner ring of the screw hole (13); The magnetic intervention hole plate (4) is movably placed in the magnetic force adjusting groove (12), and the upper surface of the magnetic intervention hole plate (4) is tightly attached to the top wall of the magnetic force adjusting groove (12).

3. A magnetic field intervention dedicated wellbore assembly according to claim 1, characterized in that: The magnetic force adjustment assembly (31) includes a clamping groove (311) arranged on the lower surface of the magnetic intervention hole plate (4), a clamping piece (312) movably mounted in the clamping groove (311), a screw rod (313) fixedly connected to the lower surface of the clamping piece (312), an external thread (314) provided on the surface of the screw rod (313), the screw rod (313) passes through the screw hole (13) and is threadedly connected with the screw hole (13), and a knob head (315) is provided at the bottom end of the screw rod (313).

4. A magnetic field intervention dedicated wellbore assembly according to claim 3, characterized in that: The magnetic force stability assembly (32) includes a plurality of reset springs (321) arranged at the four corners of the lower surface of the magnetic intervention hole plate (4), and the other end of the reset spring (321) is fixedly connected to the bottom wall of the magnetic force adjusting groove (12).

5. A magnetic field intervention dedicated wellbore assembly according to claim 1, characterized in that: The magnetic intervention hole plate (4) has three specifications of 6-hole plate, 12-hole plate and 24-hole plate, and the diameters and heights of the magnetic slots (21) and the magnet pieces (22) in the same magnetic intervention hole plate (4) are consistent; The magnetic slots (21) are arranged in one-to-one longitudinal correspondence with the hole plate chambers of the cultured cells.

6. A magnetic field intervention dedicated wellbore assembly according to claim 1, characterized in that: The outer shell (1) is provided with a raised foot pad (15) at each corner of the bottom wall.

7. A magnetic field intervention dedicated wellbore assembly according to claim 4, characterized in that: The outer shell (1) and the magnetic intervention hole plate (4) are made of transparent and corrosion-resistant materials; the reset spring (321) and the screw rod (313) are made of corrosion-resistant metal materials.

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