Methoxyphenamine hydrochloride bulk drug crushing equipment
By introducing a dispersion mechanism and a secondary crushing mechanism into the raw material pulverizing device, and utilizing fan cooling and vibration dispersion combined with the secondary crushing of crushing balls and grinding blocks, the problems of pulverizing heat affecting drug properties and low efficiency are solved, achieving efficient and uniform pulverization and collection of good drug properties.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-04-24
- Publication Date
- 2026-03-10
AI Technical Summary
Existing raw material pulverizing equipment generates heat during the pulverizing process that affects the properties of the drug, and the pulverizing efficiency is low, requiring screening and handling, which wastes time and effort.
The dispersion mechanism uses a fan to blow air in for heat dissipation and the raw material powder is dispersed by vibration of the receiving plate. Combined with the secondary crushing mechanism, the crushing balls and grinding blocks are used for secondary crushing. The air is guided and collected by a blower and connecting pipe.
It reduces the heat impact during the raw material grinding process, improves grinding efficiency and uniformity, ensures good drug properties, and improves collection efficiency.
Smart Images

Figure CN223980578U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the technical field of raw material pulverizing devices, and more specifically, to a pulverizing device for methoxyphenamine hydrochloride raw material. Background Technology
[0002] Methoxyphenamine hydrochloride is a bronchodilator mainly used to relieve symptoms of respiratory diseases such as asthma and chronic bronchitis. The pulverization of its active pharmaceutical ingredient is a critical step in the pharmaceutical process, directly affecting the uniformity, solubility, bioavailability, and quality of subsequent formulation processes.
[0003] Existing raw material pulverizing equipment typically only has a pulverizing function. Raw materials need to be sieved before pulverizing and then transported, which wastes a lot of time and effort. At the same time, the pulverized raw materials need to be collected after pulverizing, which reduces the efficiency of raw material pulverizing.
[0004] A search revealed a Chinese patent with publication number CN218250638U that discloses a rapid pulverizing device for raw pharmaceutical materials. This utility model involves pouring the raw pharmaceutical material to be pulverized from the top of the feed trough. When the second motor is started, it drives the second rotating shaft to rotate. The second rotating shaft drives the rotating rod to rotate, causing the second filter screen to move back and forth in the feed trough, shaking and filtering the raw pharmaceutical material at the top of the second filter screen. After being screened, the raw pharmaceutical material moves from the first discharge port to the bottom, and then enters the feed port from the first discharge port for further pulverization, thus achieving the effect of pulverizing directly after screening.
[0005] However, when the above-mentioned pulverizing equipment is used to rapidly pulverize the raw material powder, the raw material powder will generate a certain amount of heat due to compression and friction. This heat will affect the raw material powder itself after it is concentrated and accumulated, thus affecting the drug properties of the raw material powder. Utility Model Content
[0006] In order to overcome the above-mentioned defects of the prior art, the present invention provides a pulverizing device for methoxyphenamine hydrochloride raw material to solve the problems mentioned in the background art.
[0007] To achieve the above objectives, this utility model provides the following technical solution:
[0008] A pulverizing device for methoxyphenamine hydrochloride raw material includes a shell, a feed hopper fixedly connected to the top of the shell, a cover plate hinged to the outside of the feed hopper, two ventilation filters fixedly connected to the outside of the shell, a servo motor fixedly connected to the outside of the shell, a crushing roller fixedly connected to the output end of the servo motor, a gear fixedly connected to a section of the crushing roller, a gear meshing with one side of the gear, a crushing roller fixedly connected to the inner side of the gear, and the outer sides of the gear and the crushing roller rotatably connected to the inner side of the shell. The inner side of the shell is provided with... The device includes a dispersing mechanism; the dispersing mechanism includes a connecting frame, the outer side of which is fixedly connected to the inner side of the outer shell, three air inlet pipes fixedly connected to the outer side of the connecting frame, a filter plate one fixedly connected to one side of each air inlet pipe, a filter plate two fixedly connected to the inner side of the connecting frame, a fan fixedly connected to the inner side of each air inlet pipe, multiple shock absorbers fixedly connected to the inner side of the outer shell, a receiving plate fixedly connected to the top of each shock absorber, a vibrating motor fixedly connected to the bottom of the receiving plate, a centralized funnel fixedly connected to the inner side of the outer shell, and a secondary crushing mechanism provided on the inner side of the outer shell.
[0009] By adopting the above technical solution: using three fans to blow air into the inside of the shell to cool the crushed raw material powder, and at the same time using the vibration of the receiving plate to disperse the raw material powder, the raw material powder can move to the subsequent steps at a uniform speed.
[0010] As a further description of the above technical solution: the secondary crushing mechanism includes a second servo motor, the output end of which is fixedly connected to a rotating cone, multiple baffles are fixedly connected to the outer side of the rotating cone, a crushing ball is fixedly connected to the bottom of the rotating cone, a grinding seat is fixedly connected to the inner side of the outer shell, a guide plate is fixedly connected to the inner side of the grinding seat, a fan is fixedly connected to the outer side of the outer shell, a connecting pipe is fixedly connected to the output end of the fan, the outer side of the connecting pipe penetrates the inner side of the outer shell and extends into the interior of the grinding seat, a hopper is fixedly connected to the bottom of the outer shell, three baffles are fixedly connected to the top of the hopper, and multiple inclined air ducts are opened on the outer side of the baffles.
[0011] By adopting the above technical solution: the raw material powder is crushed in two stages using crushing balls and grinding blocks, and at the same time, multiple blowers and connecting pipes are used to blow air into the crushed raw material powder inside the grinding blocks, so that the raw material powder is concentrated through the feeding hopper under the obstruction and guidance of multiple baffles and inclined air ducts.
[0012] The technical effects and advantages of this utility model are as follows:
[0013] 1. By setting up a dispersing mechanism, compared with the existing technology, the fan blows the crushed raw material powder, which reduces the heat generated by the crushing of the raw material powder. The vibration of the receiving plate keeps the raw material powder loose, avoiding local high temperature in the raw material powder that could lead to drug decomposition, and keeping the pulverized raw material powder with good drug properties.
[0014] 2. By setting up a secondary crushing mechanism, compared with the existing technology, the secondary crushing of raw material powder by crushing balls and grinding seats makes the raw material powder more uniformly crushed. At the same time, the feeding hopper and multiple baffles enable the raw material powder to be better collected and gathered, improving the crushing completion of the crushing device. Attached Figure Description
[0015] Figure 1 This is a schematic diagram of the overall structure of this utility model.
[0016] Figure 2 This is a schematic diagram of the left side structure of this utility model.
[0017] Figure 3 This is a schematic diagram of the front structure of this utility model.
[0018] Figure 4 This is a partial schematic diagram of the connection between the connecting frame and the air inlet pipe of this utility model.
[0019] Figure 5 This is a partial schematic diagram of the connection between the rotating cone and the crushing ball of this utility model.
[0020] Figure 6 This is a partial schematic diagram of the connection between the shock absorber and the receiving plate of this utility model.
[0021] The attached diagram is labeled as follows: 1. Outer shell; 2. Feed hopper; 3. Cover plate; 4. Ventilation filter; 5. Servo motor one; 6. Crushing roller one; 7. Gear one; 8. Gear two; 9. Crushing roller two; 10. Connecting frame; 11. Air inlet pipe; 12. Filter plate one; 13. Fan; 14. Shock absorber; 15. Receiving plate; 16. Vibrating motor; 17. Centralized funnel; 18. Servo motor two; 19. Rotating cone; 20. Baffle plate; 21. Crushing ball; 22. Grinding seat; 23. Guide plate; 24. Fan; 25. Connecting pipe; 26. Discharge hopper; 27. Baffle plate; 28. Inclined air duct; 29. Filter plate two. Detailed Implementation
[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0023] The embodiments disclosed in this application are as follows: Figure 1-6 The methoxyphenamine hydrochloride raw material pulverizing equipment shown includes a shell 1, a feed hopper 2 fixedly connected to the top of the shell 1, a cover plate 3 hinged to the outside of the feed hopper 2, two ventilation filters 4 fixedly connected to the outside of the shell 1, a servo motor 5 fixedly connected to the outside of the shell 1, a crushing roller 6 fixedly connected to the output end of the servo motor 5, a gear 7 fixedly connected to a section of the crushing roller 6, a gear 8 meshing with one side of the gear 7, a crushing roller 9 fixedly connected to the inside of the gear 8, and the outside of the gear 8 and the crushing roller 9 rotatably connected to the inside of the shell 1. A dispersion mechanism is provided inside the shell 1; the dispersion mechanism includes a connecting frame 10, the outside of the connecting frame 10 fixedly connected to the inside of the shell 1, and the outside of the connecting frame 10 fixedly connected to... The system is equipped with three air inlet pipes 11. A filter plate 12 is fixedly connected to one side of the air inlet pipe 11, and a filter plate 29 is fixedly connected to the inside of the connecting frame 10. A fan 13 is fixedly connected to the inside of the air inlet pipe 11. Multiple shock absorbers 14 are fixedly connected to the inside of the outer shell 1. A receiving plate 15 is fixedly connected to the top of the shock absorber 14, and a vibrating motor 16 is fixedly connected to the bottom of the receiving plate 15. A centralized funnel 17 is fixedly connected to the inside of the outer shell 1. A secondary crushing mechanism is provided inside the outer shell 1 to blow and disperse the raw material powder after crushing by the crushing roller 16 and the crushing roller 29, and to dissipate heat. At the same time, the vibration motor 16 drives the receiving plate 15 to vibrate, so that the receiving plate 15 can uniformly convey the raw material powder to the centralized funnel 17 on one side.
[0024] Reference Figure 3 and Figure 5As shown, the secondary crushing mechanism includes a servo motor 18, with a rotating cone 19 fixedly connected to the output end of the servo motor 18. Multiple baffles 20 are fixedly connected to the outer side of the rotating cone 19. Crushing balls 21 are fixedly connected to the bottom of the rotating cone 19. A grinding seat 22 is fixedly connected to the inner side of the outer shell 1. A guide plate 23 is fixedly connected to the inner side of the grinding seat 22. A blower 24 is fixedly connected to the outer side of the outer shell 1. A connecting pipe 25 is fixedly connected to the output end of the blower 24. The connecting pipe 25 penetrates the inner side of the outer shell 1 and extends into the grinding seat 22. A hopper 26 is fixedly connected to the bottom of the outer shell 1. Three... Each baffle 27 has multiple inclined air ducts 28 on its outer side. A servo motor 218 drives a rotating cone 19, baffle 20, and crushing ball 21 to agitate and crush the raw material powder entering the central funnel 17 and grinding seat 22. At the same time, a guide plate 23 guides the air blown into the grinding seat 22 by the blower 24 and connecting pipe 25, so that the air can transport the raw material powder after secondary crushing to the top of the discharge hopper 26. The three baffles 27 and inclined air ducts 28 block and guide the raw material powder, causing it to fall downward into the inner side of the discharge hopper 26 for collection.
[0025] The working principle of this utility model is as follows: First, the raw material powder is fed into the interior of the outer shell 1 through the feed hopper 2. The servo motor 5 is started to drive the crushing roller 6 and gear 7 to rotate. Gear 7 meshes with gear 8, causing crushing roller 9 and crushing roller 6 to rotate in opposite directions. At the same time, the cover plate 3 is rotated to cover the top of the feed hopper 2. Then, three fans 13 are started to send outside air through the filter plate 12 to the interior of the connecting frame 10 through the air inlet pipe 11. The air is blown into the bottom of crushing roller 6 and crushing roller 9 through the connecting frame 10, so that the raw material powder crushed by crushing roller 6 and crushing roller 9 is dispersed by the air blown out by the connecting frame 10, and the heat generated by crushing is dissipated. Then, the crushed raw material powder falls to the top of the receiving plate 15. The vibration motor 16 drives the receiving plate 15 to vibrate up and down under the shock absorption support of the shock absorber 14. Under vibration conveying, the raw material powder moves to the concentration funnel 17 on one side, and then the raw material powder is gathered through the concentration funnel 17, causing the raw material powder to fall to the top of the grinding seat 22. Then, the servo motor 21 drives the rotating cone 19, baffle 20 and crushing ball 21 to rotate, so that the crushing ball 21 rotates and crushes the raw material powder inside the grinding seat 22. After secondary crushing, the raw material powder falls down along the grinding seat 22 into the interior of the grinding seat 22. At the same time, the blower 24 and connecting pipe 25 blow air into the interior of the grinding seat 22. When the air passes through the guide plate 23, it blows the raw material powder inside the grinding seat 22, causing the raw material powder to be blown from one side of the grinding seat 22 to the side of the hopper 26. Then, multiple baffles 27 and inclined air channels 28 block the raw material powder during the blowing process, allowing the raw material powder to fall into the interior of the hopper 26, completing the concentration of the raw material powder for subsequent collection.
[0026] All contents not described in detail in the specification are existing technologies known to those skilled in the art, and the model parameters of each electrical appliance are not specifically limited; conventional equipment can be used. Electrical control components not mentioned in this technical solution are not shown in the figures because they are existing technologies, and will not be described here.
[0027] The above are all preferred embodiments of this application, and are not intended to limit the scope of protection of this application. Therefore, all equivalent changes made in accordance with the structure, shape and principle of this application should be covered within the scope of protection of this application.
Claims
1. A methoxyphenamine hydrochloride bulk drug substance milling apparatus comprising a housing (1), characterised in that: The shell (1) top fixedly connected with feed hopper (2), the feed hopper (2) outside hinged with cover plate (3), the shell (1) outside fixedly connected with two ventilation filter screen (4), the shell (1) outside fixedly connected with servo motor one (5), the servo motor one (5) output fixedly connected with broken roll one (6), the broken roll one (6) a fixedly connected with gear one (7), the gear one (7) one side engagement has gear two (8), the gear two (8) inside fixedly connected with broken roll two (9), the gear two (8) and broken roll two (9) outside and shell (1) inside rotationally connected, the shell (1) inside is provided with dispersion mechanism; The dispersion mechanism includes connecting frame (10), the connecting frame (10) outside and shell (1) inside fixedly connected, the connecting frame (10) outside fixedly connected with three air inlet pipe (11), the air inlet pipe (11) one side fixedly connected with filter plate one (12); The shell (1) inside is provided with secondary crushing mechanism.
2. Methoxyphenamine hydrochloride drug substance milling apparatus according to claim 1, characterized in that: The connecting frame (10) inside fixedly connected with filter plate two (29), the air inlet pipe (11) inside fixedly connected with fan (13).
3. The methoxyphenamine hydrochloride drug substance milling apparatus of claim 1, wherein: The shell (1) inside fixedly connected with a plurality of shock absorber (14), the shock absorber (14) top fixedly connected with receiving plate (15), the receiving plate (15) bottom fixedly connected with vibration motor (16), the shell (1) inside fixedly connected with concentration funnel (17).
4. The methoxyphenamine hydrochloride drug substance milling apparatus of claim 1, wherein: The secondary crushing mechanism includes servo motor two (18), the servo motor two (18) output fixedly connected with rotating cone (19), the rotating cone (19) outside fixedly connected with a plurality of baffle (20), the rotating cone (19) bottom fixedly connected with broken ball (21).
5. The methoxyphenamine hydrochloride drug substance milling apparatus of claim 1, wherein: The shell (1) inside fixedly connected with grinding seat (22), the grinding seat (22) inside fixedly connected with guide vane (23), the shell (1) outside fixedly connected with fan (24).
6. Methoxyphenamine hydrochloride drug substance milling apparatus according to claim 5, characterized in that: The fan (24) output fixedly connected with connecting pipe (25), the connecting pipe (25) outside through the shell (1) inside and extends to the inside of grinding seat (22).
7. The methoxyphenamine hydrochloride drug substance milling apparatus of claim 1, wherein: The shell (1) bottom fixedly connected with the lower hopper (26), the lower hopper (26) top fixedly connected with three baffle (27), the baffle (27) outside is provided with a plurality of inclined air duct (28).
Citation Information
Patent Citations
Rapid crushing equipment for raw material medicines
CN218250638U