Paraffin section floating adsorption device

The paraffin slice adsorption device, which uses a sliding baffle mechanism and a multi-layer filtration structure, solves the problem of paraffin debris contamination, achieves efficient debris capture, prevents cross-contamination, and saves water resources, and is suitable for various experimental conditions.

CN223985920UActive Publication Date: 2026-03-10SECOND AFFILIATED HOSPITAL ZHEJIANG UNIV COLLEGE OF MEDICINE
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-03-19
Publication Date
2026-03-10

AI Technical Summary

Technical Problem

In the traditional paraffin sectioning process, paraffin debris suspended in the water tank causes contamination, affecting section quality and detection accuracy. Furthermore, existing devices have problems such as cleaning dead zones, non-adjustable partition spacing, and obstructed section retrieval angle.

Method used

The adsorption device employs a sliding baffle mechanism and a multi-layer filtration structure. The sliding baffle mechanism separates the paraffin slices, and the multi-layer filtration layers capture the debris. The spacing between the baffles can be adjusted to prevent cross-contamination and simplify the cleaning process.

Benefits of technology

It significantly improves debris capture efficiency, reduces pollution, saves water resources, prevents cross-contamination, adapts to different sizes of glass slides and water tanks, extends equipment life, and is suitable for a variety of experimental scenarios.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a floating slice adsorption device for paraffin slices. The device comprises an adsorption frame which is a cubic frame, an adsorption cavity is formed in the adsorption frame, and the adsorption frame is arranged in a test water tank; the upper end of each sliding partition plate mechanism is installed at the upper end of the adsorption frame in a sliding mode, the adsorption cavity is divided into a plurality of floating slice adsorption cavities through the sliding partition plate mechanisms, and paraffin slices are placed in each floating slice adsorption cavity for slice floating; the bottom face partition plate mechanism is installed at the bottom end of the adsorption frame, and the lower end of each sliding partition plate mechanism abuts against the upper surface of the bottom face partition plate mechanism. The device has the advantages of efficiently adsorbing suspended paraffin chips in water, adjusting the distance between the sliding partition plate mechanisms, effectively preventing cross contamination of tissue samples, being convenient to clean and replace, and avoiding frequent water change.
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Description

Technical Field

[0001] This utility model relates to the field of paraffin sections, specifically to a device for adsorbing and floating paraffin sections. Background Technology

[0002] Paraffin sectioning is widely used in pathological and forensic research. The process includes tissue fixation, dehydration, paraffin infiltration, embedding, sectioning, and slide preparation. The slide preparation (floating) step involves using a water bath or constant temperature device to unfold the paraffin roll and ensure it adheres smoothly to the glass slide. This process directly affects the quality of the section and the subsequent staining and observation results.

[0003] However, during the bleaching process, paraffin debris remaining on the sections inevitably detaches and floats in the water tank. This debris not only contaminates the water but may also adhere to the surfaces of other sections, affecting section quality. To prevent contamination during bleaching, operators typically need to frequently change the water in the tank, increasing the number of steps and wasting water. Furthermore, residual wax debris or tissue fragments can easily accumulate in crevices, and incomplete cleaning can lead to cross-contamination over long-term use. In addition, traditional paraffin section bleachers often have open-type water tanks, which can easily cause overlap or contact when multiple sections float on the same surface, leading to cross-contamination of tissue samples. This is especially problematic in high-throughput experiments, where manual operation makes it difficult to precisely control the spacing between sections, severely impacting detection accuracy.

[0004] To address the aforementioned issues, existing solutions have attempted to optimize the layout by adding separators, but limitations remain, such as unresolved cleaning dead zones, non-adjustable separator spacing, and the ease with which the slide retrieval angle is obstructed by fixed separators. Therefore, there is an urgent need to design a device with adjustable separator spacing, efficient adsorption of suspended paraffin debris in water, easy cleaning, easy replacement, and pollution prevention, in order to improve the standardization of paraffin slide preparation. Utility Model Content

[0005] To address the aforementioned technical problems, this invention proposes a flake adsorption device for paraffin slices. This device utilizes the lateral movement of a sliding partition mechanism and employs an adsorption layer to efficiently capture wax debris in the water tank, reducing cross-contamination and simultaneously lowering manual operation costs and water consumption.

[0006] The floating sheet adsorption device of this utility model is achieved by adopting the following technical solution:

[0007] The adsorption frame is a cubic frame, with an adsorption cavity formed inside the adsorption frame, and the adsorption frame is arranged in the test water tank.

[0008] Several sliding partition mechanisms are used, with the upper end of each sliding partition mechanism slidably installed on the upper end of the adsorption frame. The sliding partition mechanism divides the adsorption chamber into several flotation chambers, and paraffin slices are placed in each flotation chamber for flotation.

[0009] The bottom partition mechanism is installed at the bottom of the adsorption frame, and the lower end of each sliding partition mechanism abuts against the upper surface of the bottom partition mechanism.

[0010] The number of adsorption cavities of the divided float plates is one greater than the number of sliding partition mechanisms.

[0011] Each of the two horizontally parallel beams above the adsorption frame has a groove, and a slide rail is embedded in each groove. The track direction of each slide rail is arranged horizontally. The openings of the two slide rails are horizontal and opposite to each other. Each sliding partition mechanism is vertically arranged and has two snap-fit ​​sliders at its upper end. After the two snap-fit ​​sliders are engaged in the openings of the corresponding slide rails, they are slidably connected to the two slide rails of the adsorption frame.

[0012] After the latching slider is engaged into the opening of the slide rail, the sliding partition mechanism is secured to the adsorption frame by the latching slider and the slide rail, preventing it from falling off.

[0013] The sliding partition mechanism includes a sliding partition frame and a sliding adsorption layer. The sliding partition frame is composed of a grid structure and is generally in the shape of a cube. The vertical top and bottom surfaces of the sliding partition frame have no grid structure, while the other four surfaces have a grid structure. The upper end of each sliding partition frame is slidably connected to two slide rails of the adsorption frame via two snap-fit ​​sliders. The sliding adsorption layer is arranged inside the sliding partition frame and the lower end of the sliding adsorption layer abuts against the bottom partition mechanism.

[0014] The bottom partition mechanism includes a bottom partition frame and a bottom adsorption layer; the bottom partition frame is fixedly installed on the bottom surface of the adsorption frame and the lower end of the sliding adsorption layer abuts against the upper surface of the bottom partition frame. The bottom partition frame is composed of a grid structure and is a cubic frame in shape. One side of the bottom partition frame has no grid structure, and the other five sides have a grid structure. The bottom adsorption layer is arranged inside the bottom partition frame.

[0015] The sliding adsorption layer mainly consists of two coarse filter layers on the sides, a coarse filter layer on the bottom, and a fine filter layer arranged between the two coarse filter layers on the sides. The coarse filter layer on the bottom abuts against the upper surface of the bottom partition frame. The planes on the two coarse filter layers on the sides of the sliding adsorption layer are perpendicular to the sliding direction of the sliding partition mechanism. The bottom adsorption layer mainly consists of a coarse filter layer with a mesh structure on one side of the bottom partition mechanism, two coarse filter layers on the top and bottom, and a fine filter layer arranged in the middle.

[0016] The coarse filter layers on both sides and the bottom of the sliding adsorption layer are integrally formed; all the coarse filter layers of the bottom adsorption layer are integrally formed.

[0017] The adsorption frame, sliding partition frame, and bottom partition frame are all stainless steel frames with a thickness of 1.5mm.

[0018] The fine filtration layer is a polytetrafluoroethylene microporous filter membrane with a pore size of 0.1-0.5 μm.

[0019] The coarse filter layer is a nylon mesh with a pore size of 1-2 mm.

[0020] In the sliding adsorption layer, the length of the coarse filter layer on both sides in the vertical direction is greater than the length of the fine filter layer; in the bottom adsorption layer, the length of the two upper and lower coarse filter layers in the front and back horizontal direction is equal to the length of the fine filter layer.

[0021] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0022] 1. By combining a multi-layered filtration structure (coarse filter layer and fine filter layer) with a sliding adsorption layer and a bottom adsorption layer, the debris capture efficiency can be significantly improved, pollutants in the water tank can be reduced, frequent water changes can be avoided, and water resources can be saved.

[0023] 2. The sliding partition frame adopts an integrated design, and the sliding adsorption layer can be directly removed from the sliding partition frame for individual replacement, avoiding frequent water changes. Furthermore, the bottom adsorption layer can be replaced after the test, taking out all the adsorbed paraffin debris to avoid secondary pollution.

[0024] 3. By adjusting the spacing between the sliding partition mechanisms, overlapping or contact between slides is avoided, effectively preventing cross-contamination of tissue samples, and the slide retrieval angle is not easily obstructed by the sliding partition mechanism.

[0025] 4. The adsorption frame, sliding partition frame, and bottom partition frame are all made of stainless steel, which is suitable for high-temperature disinfection environments and extends the service life of the equipment.

[0026] 5. This utility model can be adapted to glass slides and water tanks of different specifications, and is suitable for various experimental scenarios in pathology, forensic medicine and biological research, with high versatility and practicality. Attached Figure Description

[0027] The present invention will now be described in further detail with reference to the accompanying drawings and specific embodiments, wherein:

[0028] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0029] Figure 2 This is a cross-sectional view of the slide groove of this utility model;

[0030] Figure 3 This is a side sectional view of the sliding partition mechanism of this utility model;

[0031] Figure 4 This is a schematic diagram of the sliding partition mechanism of this utility model;

[0032] Figure 5 This is a schematic diagram of the bottom partition mechanism of this utility model.

[0033] The components are: 1. Adsorption frame; 2. Sliding partition mechanism; 2-1. Sliding partition frame; 2-2. Sliding adsorption layer; 3. Bottom partition mechanism; 3-1. Bottom partition frame; 3-2. Bottom adsorption layer; 4. Slide groove; 5. Slide rail; 6. Buckle slider. Detailed Implementation

[0034] The present invention will now be described in more detail with reference to the accompanying drawings and embodiments. However, the present invention is not limited thereto. For those skilled in the art, several improvements and modifications can be made without departing from the principle of the present invention, and these improvements and modifications are also considered to be within the protection scope of the present invention. Contents not described in detail in this specification are prior art known to those skilled in the art.

[0035] like Figure 1 As shown, the float adsorption device of this utility model includes:

[0036] The adsorption frame 1 is a cubic frame, and an adsorption cavity is formed inside the adsorption frame 1. The adsorption frame 1 is arranged in the test water tank.

[0037] Several sliding partition mechanisms 2 are installed horizontally on the upper end of the adsorption frame 1. The sliding partition mechanism 2 divides the adsorption chamber into several floating piece adsorption chambers. Paraffin slices are placed in each floating piece adsorption chamber for floating. Through the flexible sliding of the sliding partition mechanism 2, the paraffin debris generated by different paraffin slices is concentrated into their respective sliding adsorption layers 2-2.

[0038] The bottom partition mechanism 3 is installed at the bottom of the adsorption frame 1, and the lower end of each sliding partition mechanism 2 abuts against the upper surface of the bottom partition mechanism 3.

[0039] In practice, at the start of the test, the test tank is filled with water, and the float adsorption device is placed precisely in the test tank. The number of float adsorption chambers is one greater than the number of sliding baffle mechanisms 2.

[0040] like Figure 2 and Figure 3As shown, each of the two horizontally parallel beams above the adsorption frame 1 has a groove 4, and each groove 4 is fitted with a slide rail 5. The track direction of each slide rail 5 is consistent with the direction of the horizontally arranged beams, and they are all arranged horizontally. The openings of the two slide rails 5 are horizontal and opposite to each other. Each sliding partition mechanism 2 is vertically arranged and each sliding partition mechanism 2 has two snap-fit ​​sliders 6 at its upper end. After the two snap-fit ​​sliders 6 are engaged into the openings of the corresponding slide rails 5, they are slidably connected to the two slide rails 5 of the adsorption frame 1, so that the sliding partition mechanism 2 can slide horizontally. The sliding partition mechanism 2 is used to adsorb the paraffin debris generated during the bleaching process of paraffin slices.

[0041] After the latching slider 6 is engaged in the opening of the slide rail 5, the sliding partition mechanism 2 is secured to the adsorption frame 1 by the latching slider 6 and the slide rail 5 and will not fall off.

[0042] In practice, the spacing between adjacent sliding baffle mechanisms 2 can be flexibly adjusted according to the size and quantity of different paraffin slices in the experiment, so that different paraffin slices can be placed in the corresponding floating slice adsorption chamber. After the paraffin slices are floated, the paraffin debris generated is collected by the flexible sliding of the sliding baffle mechanism 2, which makes it easy to clean.

[0043] like Figure 4 As shown, the sliding partition mechanism 2 includes a sliding partition frame 2-1 and a sliding adsorption layer 2-2. The sliding partition frame 2-1 is composed of a grid structure and is in the shape of a cube. The vertical top and bottom surfaces of the sliding partition frame 2-1 have no grid structure, while the other four surfaces are grid structures. The upper vertical end of each sliding partition frame 2-1 is slidably connected to the two slide rails 5 of the adsorption frame 1 through two snap-fit ​​sliders 6. The sliding adsorption layer 2-2 is arranged inside the sliding partition frame 2-1 and the lower end of the sliding adsorption layer 2-2 abuts against the bottom partition mechanism 3.

[0044] The grid structure of the sliding baffle frame 2-1 is designed to effectively fix the sliding adsorption layer 2-2 and ensure water flow. The sliding baffle frame 2-1 is set vertically without a grid structure on top so that the sliding adsorption layer 2-2 can be removed from the top for replacement at any time during the experiment without changing the water, so the experiment can continue after replacement.

[0045] like Figure 5As shown, the bottom baffle mechanism 3 includes a bottom baffle frame 3-1 and a bottom adsorption layer 3-2. The bottom baffle frame 3-1 is fixedly installed on the bottom surface of the adsorption frame 1, and the lower end of the sliding adsorption layer 2-2 abuts against the upper surface of the bottom baffle frame 3-1. The bottom baffle frame 3-1 is composed of a grid structure and is generally cubic. One side of the bottom baffle frame 3-1 is without a grid structure, while the other five sides are grid structures. The bottom adsorption layer 3-2 is arranged inside the bottom baffle frame 3-1. The grid structure of the bottom baffle frame 3-1 is used to effectively fix the bottom adsorption layer 3-2 and ensure water flow. The bottom baffle frame 3-1 is designed with one side without a grid structure so that the bottom adsorption layer 3-2 can be easily placed inside the bottom baffle frame 3-1 during device assembly, and the bottom adsorption layer 3-2 is removed from the bottom baffle frame 3-1 only after the floater is finished. In specific implementation, such as... Figure 5 As shown, the left side of the bottom partition frame 3-1 has no network structure.

[0046] The sliding adsorption layer 2-2 mainly consists of two coarse filter layers on the sides, a coarse filter layer on the bottom, and a fine filter layer arranged between the two coarse filter layers on the sides. The coarse filter layer on the bottom abuts against the upper surface of the bottom partition frame 3-1. The planes containing the two coarse filter layers on the sides of the sliding adsorption layer 2-2 are perpendicular to the sliding direction of the sliding partition mechanism 2. The bottom adsorption layer 3-2 mainly consists of a coarse filter layer with a mesh structure on one side of the bottom partition mechanism 3, two upper and lower coarse filter layers, and a fine filter layer arranged in the middle. In specific implementation, such as... Figure 5 As shown, the right side of the bottom adsorption layer 3-2 is a coarse filter layer.

[0047] The two side coarse filter layers and the bottom coarse filter layer of the sliding adsorption layer 2-2 are integrally formed to ensure that the sliding adsorption layer 2-2 can adsorb and remove all paraffin debris more efficiently during replacement and avoid secondary pollution; all coarse filter layers of the bottom adsorption layer 3-2 are integrally formed.

[0048] The adsorption frame 1, sliding partition frame 2-1, and bottom partition frame 3-1 are all stainless steel frames, which have high temperature resistance and corrosion resistance, and a thickness of 1.5mm. In specific implementation, the length, width, and height of the adsorption frame 1, sliding partition frame 2-1, and bottom partition frame 3-1 are suitable for the test water tanks commonly used in the market for floating paraffin slices.

[0049] The fine filtration layers of the sliding adsorption layer 2-2 and the bottom adsorption layer 3-2 are made of polytetrafluoroethylene (PTFE) microporous membranes with a pore size of 0.1-0.5 μm, capable of filtering paraffin debris with a diameter of 0.1-0.5 μm. All coarse filtration layers of the sliding adsorption layer 2-2 and the bottom adsorption layer 3-2 are made of nylon mesh with a pore size of 1-2 mm, capable of filtering paraffin debris with a diameter of 1-2 mm, further ensuring water cleanliness.

[0050] In the sliding adsorption layer 2-2, the length of the coarse filter layer on both sides in the vertical direction is greater than the length of the fine filter layer. In order to facilitate the experimenters to directly pinch the coarse filter layer on both sides to remove the entire sliding adsorption layer 2-2 for replacement.

[0051] In the bottom adsorption layer 3-2, the lengths of the two upper and lower coarse filter layers in the front-to-back horizontal direction are equal to the lengths of the fine filter layer. This is to ensure that all surfaces of the bottom partition mechanism 3 are flat and without protrusions, so that it can be better placed in the test water tank, thereby maintaining the stability of the floating plate adsorption device in the test water tank.

[0052] Example 1

[0053] This embodiment provides a device for adsorbing and floating paraffin slices. The sliding partition mechanism 2 is configured with 3 components, and the other structures are consistent with the above description.

[0054] Example 2

[0055] As a preferred embodiment of this utility model, the main difference between this embodiment and Embodiment 1 is that the size of the adsorption frame 1 is 150mm×80mm×40mm, which is suitable for small experimental water tanks; the number of sliding partition mechanisms 2 is reduced to one, which is suitable for low-throughput experimental scenarios. In use, other structures are basically the same as in Embodiment 1.

[0056] Example 3

[0057] As another preferred embodiment of this utility model, the main difference between this embodiment and Embodiment 1 is that: a double- or triple-layer sliding groove 4 and a sliding rail 5 are added above the adsorption frame 1, allowing multiple sliding partition mechanisms 2 to slide at different heights; the spacing of each sliding partition mechanism 2 can be independently adjusted to adapt to different experimental requirements. In use, other structures are basically the same as in Embodiment 1.

[0058] Example 4

[0059] As another preferred embodiment of this utility model, the main difference between this embodiment and Embodiment 1 is that: the adsorption frame 1 has a newly added standardized interface, which can be installed in an automatic filter bleaching machine and supports robotic arm operation; the slide rail 5 is changed to an automatic adjustment mode, and the spacing of the sliding partition mechanism 2 can be adjusted by the automated system; the adsorption frame 1 is equipped with a micro-sensor and a replaceable filter cartridge system, which can detect the density of paraffin debris in the water, and automatically prompt the replacement of the sliding adsorption layer 2-2 when the debris accumulation reaches a threshold, and quickly replace the filter cartridge without stopping the machine. In use, other structures are basically the same as in Embodiment 1.

[0060] This invention has the advantages of efficient adsorption of suspended paraffin debris in water, adjustable sliding partition spacing, effective prevention of cross-contamination of tissue samples, easy cleaning and replacement, and avoidance of frequent water changes.

[0061] In summary, any other corresponding modifications made by those skilled in the art based on the technical solution and concept of this utility model without creative mental effort after reading this utility model document are all within the scope of protection of this utility model.

[0062] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A device for adsorbing a paraffin section during deparaffinization, characterized by, The application relates to a paraffin section floating and adsorbing device. The application relates to a paraffin section floating and adsorbing device.

2. The paraffin section floating and adsorbing device according to claim 1, characterized in that: two transversely-parallel arranged cross beams are arranged above the adsorbing frame (1), and a sliding groove (4) is formed in each cross beam; a sliding rail (5) is embedded in each sliding groove (4), and the rail direction of each sliding rail (5) is arranged along the transverse direction; the opening directions of the two sliding rails (5) are horizontally arranged and oppositely arranged; each sliding partition mechanism (2) is vertically arranged, and two buckle sliding blocks (6) are arranged at the upper end of each sliding partition mechanism (2); after the two buckle sliding blocks (6) are buckled into the openings of the corresponding sliding rails (5), the two buckle sliding blocks (6) are slidably connected with the two sliding rails (5) of the adsorbing frame (1) respectively.

3. The paraffin section floating and adsorbing device according to claim 1, characterized in that: the sliding partition mechanism (2) comprises a sliding partition frame (2-1) and a sliding adsorbing layer (2-2); the sliding partition frame (2-1) is composed of a grid structure and is in the form of a cubic frame; the vertical upper and lower surfaces of the sliding partition frame (2-1) are free of the grid structure, and the other four surfaces are all grid structures; the upper end of each sliding partition frame (2-1) is slidably connected with the two sliding rails (5) of the adsorbing frame (1) through the two buckle sliding blocks (6); and the sliding adsorbing layer (2-2) is arranged in the sliding partition frame (2-1) and abuts against the bottom partition mechanism (3) at the lower end.

4. The paraffin section floating and adsorbing device according to claim 3, characterized in that: the bottom partition mechanism (3) comprises a bottom partition frame (3-1) and a bottom adsorbing layer (3-2); the bottom partition frame (3-1) is fixedly installed on the bottom surface of the adsorbing frame (1) and abuts against the upper surface of the bottom partition frame (3-1) at the lower end of the sliding adsorbing layer (2-2); the bottom partition frame (3-1) is composed of a grid structure and is in the form of a cubic frame; one side surface of the bottom partition frame (3-1) is free of the grid structure, and the other five surfaces are all grid structures; and the bottom adsorbing layer (3-2) is arranged in the bottom partition frame (3-1).

5. The paraffin section floating and adsorbing device according to claim 4, characterized in that: ​ ​ ​ ​ ​ The sliding adsorption layer (2-2) is mainly composed of two layers of side coarse filter layers, a bottom coarse filter layer and a fine filter layer arranged between the two layers of side coarse filter layers, and the bottom coarse filter layer abuts against the upper surface of the bottom partition frame (3-1); the planes where the two layers of side coarse filter layers in the sliding adsorption layer (2-2) are perpendicular to the sliding direction of the sliding partition mechanism (2); and the bottom adsorption layer (3-2) is mainly composed of a coarse filter layer provided on one side of a grid structure, two upper and lower coarse filter layers and a fine filter layer arranged in the middle.

6. The paraffin section floating and adsorbing device according to claim 5, characterized in that: The two layers of side coarse filter layers and the bottom coarse filter layer of the sliding adsorption layer (2-2) are integrally formed; and all the coarse filter layers of the bottom adsorption layer (3-2) are integrally formed.

7. The paraffin section floating and adsorbing device according to claim 4, characterized in that: The adsorption frame (1), the sliding partition frame (2-1) and the bottom partition frame (3-1) are all stainless steel frames with a thickness of 1.5 mm.

8. The paraffin section floating and adsorbing device according to claim 5, characterized in that: The fine filter layer is a polytetrafluoroethylene microporous filter membrane, and the pore size of the polytetrafluoroethylene microporous filter membrane is 0.1-0.5 μm.

9. The paraffin section floating and adsorbing device according to claim 5, characterized in that: The coarse filter layer is a nylon mesh, and the pore size of the nylon mesh is 1-2 mm.

10. The paraffin section floating and adsorbing device according to claim 5, characterized in that: In the sliding adsorption layer (2-2), the length of the two layers of side coarse filter layers in the vertical direction is greater than the length of the fine filter layer; and in the bottom adsorption layer (3-2), the length of the two layers of upper and lower coarse filter layers in the front-rear horizontal direction is equal to the length of the fine filter layer.