High-performance liquid phase exhaust device

Abstract

The utility model discloses a high performance liquid phase exhaust device which comprises an exhaust box installed in a high performance liquid chromatograph, a plurality of partition plates are fixedly installed in the exhaust box and divide a space to form a partition cavity, a plug plate is movably arranged in the partition cavity, and the plug plate divides the partition cavity to form a liquid cavity and an air cavity. A through cavity communicated with outside air is formed in the exhaust box, and the multiple air cavities are communicated and matched with the through cavity. According to the high-performance liquid-phase exhaust device provided by the utility model, various medicaments enter the liquid cavity for temporary storage through the plurality of separation cavities before being mixed, redundant bubbles in the medicaments float and gather to remove residual gas in the medicaments and guarantee the mixing efficiency, and meanwhile, the extruded gas cavity is diffused to the through cavity to apply pressure to the rest of the plug plates, so that the gas in the medicaments can be exhausted, and the mixing efficiency is improved. The device is used for enabling the pressures of a plurality of liquid cavities to tend to be the same and enabling the pressures of medicaments to be gradually the same before mixing, thereby ensuring the interaction effect among medicament molecules, improving the medicament mixing efficiency and ensuring the accuracy of experimental results.

Description

Technical Field

[0001] This utility model relates to the field of medical experimental equipment technology, and more specifically to a high-efficiency liquid phase exhaust device. Background Technology

[0002] During the use of a high-performance liquid chromatograph, multiple reagents need to be mixed, and the air present in the mixed reagents needs to be discharged through the exhaust valve to ensure that the reagents are mixed evenly.

[0003] According to the publication (announcement) number: CN209829829U, the publication (announcement) date: 2019-12-24, a liquid chromatograph exhaust hood is disclosed.

[0004] In the prior art, including the aforementioned patent, the medicine bottle containing the reagent is generally placed in a frame above the high-performance liquid chromatograph, and multiple transparent tubing is inserted into the medicine bottle for mixing using a pump. However, because air is present inside the tubing during placement, it needs to be expelled during extraction. The tubing needs to be twisted during transport, which can easily cause creases in some parts of the tubing. This results in air bubbles when the tubing transports the reagent, and these small amounts of air bubbles enter the reagent mixing chamber, increasing the space for reagent molecules to move and easily interfering with the mixing efficiency, thus affecting the accuracy of the experimental results. Utility Model Content

[0005] The purpose of this invention is to provide a high-efficiency liquid phase exhaust device to solve the problems mentioned above.

[0006] To achieve the above objectives, this utility model provides the following technical solution:

[0007] A high-performance liquid chromatography exhaust device includes a high-performance liquid chromatograph equipped with a pipeline rack and an exhaust valve, and an exhaust box installed in the high-performance liquid chromatograph, wherein multiple partitions are fixedly installed in the exhaust box and the space is divided to form a compartment.

[0008] A stopper plate is movably disposed in the cavity, and the stopper plate divides the cavity to form a liquid cavity and a gas cavity. The exhaust box is provided with a passage cavity that communicates with the outside air, and multiple gas cavities are connected and cooperate with the passage cavity.

[0009] Preferably, the exhaust box is fixedly equipped with multiple liquid inlets, and each liquid inlet is provided with a replenishment inlet that communicates with the liquid chamber.

[0010] Preferably, symmetrically arranged guide plates are fixedly installed on the stopper plate, and a blocking port is also provided in the liquid inlet. In the default state, the end of the guide plate is inserted into the blocking port.

[0011] Preferably, a vertically arranged sealing plate is fixedly installed on the guide plate, and the sealing plate abuts against the inlet.

[0012] Preferably, a slide bar is fixedly installed on the guide plate, and a slide track for the slide bar to slide is provided on the inner wall of the exhaust box.

[0013] Preferably, the side wall of the exhaust box has a notch that communicates with the through cavity, and an exhaust plate is hinged in the notch.

[0014] Preferably, the exhaust plate abuts against the slide bar to open the passage cavity.

[0015] Preferably, the slide port faces the exhaust plate.

[0016] Preferably, a sealing gasket is fixedly installed on the exhaust plate.

[0017] Preferably, the sealing gasket is a rubber gasket.

[0018] In the above technical solution, the high-efficiency liquid phase exhaust device provided by this utility model has the following beneficial effects: multiple cavities allow various reagents to enter the liquid cavity for temporary storage before mixing, and allow excess bubbles in the reagents to float and gather, which is used to remove residual gas in the reagents and ensure mixing efficiency. At the same time, the compressed gas cavity diffuses into the through cavity to put pressure on the remaining stopper plate, so that the pressure of multiple liquid cavities tends to be the same, and the pressure of the reagents before mixing gradually becomes the same, thereby ensuring the interaction effect between reagent molecules, improving reagent mixing efficiency, and ensuring the accuracy of experimental results. Attached Figure Description

[0019] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in this utility model. For those skilled in the art, other drawings can be obtained based on these drawings.

[0020] Figure 1 A schematic diagram of the assembly of a high-performance liquid chromatograph without the door panel and exhaust box provided for an embodiment of this utility model;

[0021] Figure 2 This is a schematic cross-sectional view of the end face of the exhaust box provided in an embodiment of the present utility model;

[0022] Figure 3 This is a side sectional view of the exhaust box provided in an embodiment of the present utility model;

[0023] Figure 4 This is a schematic diagram of the plug plate from above, provided for an embodiment of the present invention.

[0024] Explanation of reference numerals in the attached figures:

[0025] 1. High-performance liquid chromatograph; 11. Pipeline rack; 12. Exhaust valve; 2. Exhaust box; 21. Partition plate; 22. Chamber; 23. Liquid inlet; 231. Make-up inlet; 232. Closure port; 3. Plug plate; 31. Guide plate; 32. Sliding bar; 321. Slide rail; 33. Sealing plate; 4. Exhaust plate; 41. Liquid chamber; 42. Gas chamber; 43. Through chamber. Detailed Implementation

[0026] To enable those skilled in the art to better understand the technical solution of this utility model, the present utility model will be further described in detail below with reference to the accompanying drawings.

[0027] like Figure 1-4 As shown, a high-performance liquid chromatography exhaust device includes a high-performance liquid chromatograph 1 equipped with a pipe rack 11 and an exhaust valve 12, and an exhaust box 2 installed in the high-performance liquid chromatograph 1. Multiple partitions 21 are fixedly installed in the exhaust box 2, and the space is divided to form a cavity 22.

[0028] A stopper plate 3 is movably disposed in the partition 22, and the stopper plate 3 divides the partition 22 to form a liquid chamber 41 and a gas chamber 42. The exhaust box 2 is provided with a passage 43 that communicates with the outside air, and multiple gas chambers 42 are connected and cooperate with the passage 43.

[0029] Specifically, the pipe rack 11 is used to neatly arrange the hoses, and the exhaust valve 12 installed in the high performance liquid chromatograph 1 is used to discharge the gas in the mixed reagent. These are existing technologies and will not be described in detail here.

[0030] Furthermore, the exhaust box 2 is fixed by a bracket, and the partition 21 maintains a predetermined distance from the top of the exhaust box 2 to allow airflow to pass over the plug plate 3.

[0031] Furthermore, a rubber ring that slides in the cavity 22 is fixedly sleeved on the side wall of the stopper plate 3, and the gap reserved by the partition plate 21 is used to form a through cavity 43, so that the air cavity 42 can be compressed and pressure is transferred to the through cavity 43.

[0032] Multiple cavities 22 allow various reagents to be temporarily stored in the liquid cavity 41 before mixing, and allow excess air bubbles in the reagents to float and gather, which removes residual gas in the reagents and ensures mixing efficiency. The air pressure causes the stopper plate 3 to move upward to ensure the gas storage space in the liquid cavity 41. At the same time, the compressed air cavity 42 diffuses into the through cavity 43 to put pressure on the remaining stopper plates 3, so that the pressure in the multiple liquid cavities 41 tends to be the same, and the pressure on the reagents gradually becomes the same before mixing, thereby ensuring the interaction effect between reagent molecules, improving the reagent mixing efficiency, and ensuring the accuracy of experimental results.

[0033] As a further embodiment of this utility model, a plurality of liquid inlets 23 are fixedly installed on the exhaust box 2, and the liquid inlets 23 are provided with a replenishment inlet 231 communicating with the liquid chamber 41.

[0034] Specifically, the outlet is arranged opposite to the inlet 23 on the exhaust box 2, and the outlet is connected to the drug mixing chamber and the exhaust valve 12.

[0035] Furthermore, the liquid inlet 23 located at the bottom side of the exhaust box 2 can discharge the medicine upwards by turning it, that is, it enters the liquid chamber 41 from the replenishment inlet 231.

[0036] The inlet 23 ensures the connection and operation space for multiple hoses, while the agent can also be normally delivered and discharged through the lower half of the liquid chamber 41, and the residual gas can also exert upward pressure on the stopper plate 3.

[0037] As another embodiment provided by this utility model, a symmetrically arranged guide plate 31 is fixedly installed on the plug plate 3, and a blocking port 232 is also provided in the liquid inlet 23. In the default state, the end of the guide plate 31 is inserted into the blocking port 232.

[0038] Specifically, the lower end of the guide plate 31 is rounded to make the insertion of the plug 232 smoother.

[0039] The guide plate 31 provides support for the up-and-down movement of the plug plate 3, and can also seal off the bend in the reagent delivery, so that there will be no reagent contamination or leakage when the exhaust box 2 is not in operation, thus ensuring experimental safety.

[0040] As another embodiment further provided by this utility model, a vertically arranged sealing plate 33 is fixedly installed on the guide plate 31, and the sealing plate 33 abuts against the inlet 231.

[0041] Specifically, a float plate is fixedly installed on the lower end face of the sealing plate 33, meaning that the density of the float plate is less than the density of the reagent.

[0042] When the sealing plate 33 is subjected to buoyancy, the auxiliary plug plate 3 moves upward to ensure the efficiency of air pressure transmission. In the default state, the weight can also be used to make the sealing plate 33 press against the floating plate and seal the inlet 231, achieving a double isolation effect of the inlet and outlet.

[0043] As another embodiment of this utility model, a slide bar 32 is fixedly installed on the guide plate 31, and a slide rail 321 for the slide bar 32 to slide is provided on the inner wall of the exhaust box 2.

[0044] The combination of slider 32 and slide rail 321 ensures the stability and guiding effect of the vertical movement of guide plate 31.

[0045] As another embodiment of this utility model, the side wall of the exhaust box 2 is provided with a notch communicating with the through cavity 43, and an exhaust plate 4 is hinged in the notch.

[0046] Specifically, a torsion spring is provided at the hinge position of the exhaust plate 4. The torsion spring and its installation method are existing technologies and will not be described in detail here. Moreover, the torsion force of the torsion spring is greater than the pressure in the cavity 43.

[0047] The exhaust plate 4 can open the top of the exhaust box 2 to release the pressurized gas in the passage cavity 43, thereby ensuring the normal movement of the plug plate 3.

[0048] As another embodiment of this utility model, the exhaust plate 4 abuts against the slide bar 32 to open the passage cavity 43.

[0049] Specifically, the ends of the exhaust plate 4 are rounded so that the slide bar 32 can slide against it.

[0050] The upward-moving slide bar 32 pushes the exhaust plate 4 to deflect, thereby opening the passage cavity 43 to release air and ensure normal air pressure delivery and discharge.

[0051] As another embodiment further provided in this utility model, the port of slide 321 faces the exhaust plate 4.

[0052] Specifically, the slide 321 near the notch has an end so that the slide bar 32 can slide out of the slide 321 and abut against the exhaust plate 4, while the slide 321 on the other side is extended to compensate for the abutment path of the slide bar 32.

[0053] By using different settings for the two slides 321, the normal movement of the stopper plate 3 and the normal release of air pressure are ensured, thereby improving exhaust efficiency. Finally, after the equipment stops running, the stopper plate 3 is moved up to the notch to release the air pressure in the liquid chamber 41.

[0054] As another embodiment of this utility model, a sealing gasket is fixedly installed on the exhaust plate 4.

[0055] By setting a sealing gasket, the exhaust plate 4 is sealed to the air chamber 42 in the default state, ensuring the balanced diffusion of air pressure.

[0056] As another embodiment further provided in this utility model, the sealing gasket is specifically a rubber gasket.

[0057] The use of rubber gaskets ensures a tight seal, making the interior of exhaust box 2 more stable and safe.

[0058] Working principle: Multiple cavities 22 allow various agents to enter the liquid cavity 41 for temporary storage before mixing, and allow excess air bubbles in the agents to float and gather, which is used to remove residual gas in the agents. The air pressure causes the stopper plate 3 to move upward to ensure the gas storage space in the liquid cavity 41. At the same time, the compressed air cavity 42 diffuses into the through cavity 43 to put pressure on the remaining stopper plates 3, so that the pressure of multiple liquid cavities 41 tends to be the same, and the pressure of the agents gradually becomes the same before mixing, thereby ensuring the interaction effect between agent molecules.

[0059] The foregoing description only illustrates certain exemplary embodiments of the present invention. Undoubtedly, those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the above drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. A high performance liquid exhaust device comprising a high performance liquid chromatograph (1) provided with a line rack (11) and an exhaust valve (12), characterized in that, Also include the exhaust tank (2) installed in the high performance liquid chromatograph (1), the exhaust tank (2) is fixedly installed with multiple partitions (21), and is divided to form the partition cavity (22); The plug plate (3) is movably arranged in the partition cavity (22), and the plug plate (3) divides the partition cavity (22) to form the liquid cavity (41) and the air cavity (42), the exhaust tank (2) is provided with the communicating cavity (43) communicated with the outside air, and multiple air cavities (42) are communicated with the communicating cavity (43).

2. The high performance liquid exhaust device of claim 1, wherein, Multiple liquid inlets (23) are fixedly installed on the exhaust tank (2), and the liquid inlets (23) are provided with the supplement inlet (231) communicated with the liquid cavity (41).

3. The high performance liquid exhaust device of claim 2, wherein, The plug plate (3) is fixedly installed with symmetrically arranged guide plates (31), and the liquid inlets (23) are also provided with occlusion ports (232), and the end of the guide plate (31) is inserted into the occlusion port (232) in the default state.

4. The high performance liquid exhaust device of claim 3, wherein, The guide plate (31) is fixedly installed with vertically arranged sealing plates (33), and the sealing plates (33) are in abutting cooperation with the supplement inlet (231).

5. The high performance liquid exhaust device of claim 3, wherein, The guide plate (31) is fixedly installed with a sliding strip (32), and the inner wall of the exhaust tank (2) is provided with a sliding channel (321) for the sliding strip (32) to slide.

6. The high performance liquid exhaust device of claim 5, wherein, The side wall of the exhaust tank (2) is provided with a notch communicated with the communicating cavity (43), and the exhaust plate (4) is hingedly arranged in the notch.

7. The high performance liquid exhaust device of claim 6, wherein, The exhaust plate (4) is in abutting cooperation with the sliding strip (32) to open the communicating cavity (43).

8. The high performance liquid exhaust device of claim 7, wherein, The port of the sliding channel (321) faces the exhaust plate (4).

9. The high performance liquid exhaust device of claim 7, wherein, The sealing gasket is fixedly installed on the exhaust plate (4).

10. The high performance liquid exhaust device of claim 9, wherein, The sealing gasket is rubber gasket.

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