Stem cell exosome preservation device
By introducing a constant temperature water bath component and a homogenization component into the stem cell exosome preservation device, the impact of temperature changes on stem cell activity was resolved, achieving stable temperature control and uniform heating, thus improving the storage effect.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-07
- Publication Date
- 2026-03-13
AI Technical Summary
Existing stem cell exosome preservation devices cannot prevent changes in external temperature during storage, which leads to a decrease in stem cell activity.
It adopts a constant temperature water bath component and a homogenization component. The temperature is controlled by the constant temperature water bath and the tank is rotated at a constant speed in the water bath by a motor and a rotating shaft, so as to ensure constant temperature and uniform heating.
Maintaining stem cell exosomes at a suitable temperature enhances their activity and storage effectiveness.
Smart Images

Figure CN223987603U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of stem cell exosome preservation technology, and in particular to a stem cell exosome preservation device. Background Technology
[0002] A stem cell exosome preservation device is a specialized instrument designed for storing and preserving stem cell exosomes. It typically includes a housing, a support structure, a dish fixation mechanism, and a temperature control system. The housing utilizes a complex support and rotation structure to ensure the dishes remain vertical during movement, minimizing collisions between the stem cell exosomes and the dish's inner wall, thereby enhancing their viability.
[0003] Chinese invention patent application CN214962226U discloses a stem cell exosome preservation device. This patent relates to the field of stem cell preservation technology. The device includes a box with a hinged cover mounted on one side via a hinge block and a hinge rod. Inside the box, a storage mechanism for holding stem cell exosomes is installed via a storage cavity. This preservation device can control the temperature around the storage compartment in real time, ensuring the temperature inside the storage compartment remains between 4-8°C. It controls the temperature outside the device without refrigerant or electricity, thus preventing external heat from being conducted into the device and disrupting the internal temperature balance. This ensures the internal temperature is unaffected by external environmental factors, guaranteeing effective preservation of stem cell exosomes. Real-time intelligent control of the internal temperature ensures smooth airflow at the bottom of the device, preventing heat accumulation at the bottom of the storage compartment.
[0004] In existing technologies, stem cell exosome preservation devices mainly use storage tubes placed inside specific storage boxes. However, the activity of exosome stem cells is affected by changes in external temperature during storage, and existing storage devices cannot avoid temperature changes, resulting in a significant reduction in storage effectiveness. Utility Model Content
[0005] The purpose of this invention is to address the shortcomings of existing technologies by proposing a stem cell exosome preservation device.
[0006] To achieve the above objectives, the present invention adopts the following technical solution:
[0007] A stem cell exosome preservation device includes a sealing cap and further includes:
[0008] The constant temperature water bath assembly includes a water bath tank, a heating rod is provided on the side wall of the water bath tank, a heater is installed on one side of the heating rod, a temperature sensor is installed inside the water bath tank, a controller is connected to one side of the temperature sensor, and a cable is installed between the controller and the heater.
[0009] A further technical solution involves a support plate on one side of the water bath tank, and a water bath chamber inside the water bath tank.
[0010] A further technical solution involves filling the interior of the water bath chamber with purified water.
[0011] Further technical solutions also include:
[0012] The container assembly includes a can that is mounted on one side of a sealing cap, and the interior of the can has a container compartment.
[0013] A further technical solution involves placing stem cell exosomes inside the container, with the container mounted on the surface of a shelf.
[0014] Further technical solutions also include:
[0015] The homogenizing component includes a slot installed on one side of the tank, a pin installed inside the slot, a rotating shaft installed on one side of the pin, and a motor installed on one side of the rotating shaft.
[0016] A further technical solution involves a cross-shaped pin structure for the pin, a support array at the bottom of the water bath tank, and a sealing ring at the point where the rotating shaft connects with the water bath tank.
[0017] Compared with the prior art, the present invention provides a stem cell exosome preservation device, which has the following beneficial effects:
[0018] By using a constant-temperature water bath assembly, the temperature inside the collection tube is consistently maintained at a suitable level for stem cell survival. If the temperature drops to the preset level, it is detected by a temperature sensor, and the controller activates the heater to reheat the water bath, restoring the temperature to the specified level. In other words, this device ensures the water temperature remains optimal for stem cell survival.
[0019] The homogenization component is designed to ensure that the biomaterials inside the storage box are heated evenly by using a motor and a rotating shaft to drive the storage box through a cross-shaped slot and a cross pin during use. Attached Figure Description
[0020] Figure 1 This is a schematic diagram of the structure of a stem cell exosome preservation device proposed in this utility model;
[0021] Figure 2 An explosion of a stem cell exosome preservation device proposed in this utility model Figure 1 Structural diagram;
[0022] Figure 3 An explosion of a stem cell exosome preservation device proposed in this utility model Figure 2 Structural diagram;
[0023] Figure 4 This is a schematic diagram of the longitudinal section of a stem cell exosome preservation device proposed in this utility model.
[0024] In the diagram: 1. Sealing cap; 2. Constant temperature water bath assembly; 3. Homogenization assembly; 4. Tank; 5. Slot; 6. Pin; 7. Shaft; 8. Motor; 9. Water bath tank; 10. Shelf; 11. Heating rod; 12. Heater; 13. Temperature sensor; 14. Controller; 15. Cable; 16. Container compartment; 17. Water bath compartment; 18. Support; 19. Sealing ring. Detailed Implementation
[0025] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.
[0026] Example 1: Refer to Figure 1 - Figure 4 A stem cell exosome preservation device includes a sealing cap 1, which is a component for sealing a container 4, and further includes:
[0027] A constant temperature water bath assembly 2 includes a water bath tank 9, with a water bath chamber 17 inside the tank 9 serving as the water bath portion. A heating rod 11 is installed on the side wall of the water bath tank 9, and a heater 12 is connected to one side of the heating rod 11. The heating rod 12 controls the heating of the water bath tank 9 by the heating rod 11. A temperature sensor 13 is installed inside the water bath tank 9 to detect the water temperature inside in real time. A controller 14 controls the operation of the heater 12. A cable 15 connects the controller 14 to the heater 12.
[0028] The aforementioned stem cell exosome preservation device includes a shelf 10 on one side of the water bath jar 9, which is where the jar 4 is placed. The interior of the water bath jar 9 contains a water bath chamber 17, which is a temperature-controlled area.
[0029] The aforementioned stem cell exosome preservation device has a water bath chamber 17 filled with purified water to achieve the effect of a water bath.
[0030] The aforementioned stem cell exosome preservation device further includes:
[0031] The container assembly includes a can 4 that is mounted on one side of a sealing cap 1. The interior of the can 4 is a part for placing stem cell exosomes, and the interior of the can 4 is provided with a container chamber 16.
[0032] The aforementioned stem cell exosome preservation device has stem cell exosomes inside the holding chamber 16, and the jar 4 is placed and installed on the surface of the shelf 10.
[0033] The aforementioned stem cell exosome preservation device further includes:
[0034] The homogenizing component 3 includes a slot 5 that is fitted onto one side of the tank 4. The slot 5 is used for locking and positioning pins 6. Pins 6 are fitted inside the slot 5, and a rotating shaft 7 is fitted onto one side of each pin 6. A motor 8 controls the rotation of the tank 4 via the rotating shaft 7. A motor 8 is fitted onto one side of the rotating shaft 7.
[0035] The stem cell exosome preservation device described above includes a pin 6 with a cross-shaped structure, a support 18 arrayed at the bottom of the water bath 9, and a sealing ring 19 at the joint between the rotating shaft 7 and the water bath 9. The main function of the sealing ring 19 is to prevent water leakage at the joint.
[0036] Working principle:
[0037] In the actual design process of this utility model, to avoid the following defects existing in the prior art: "In the prior art, stem cell exosome preservation devices mainly use storage tubes placed inside a specific storage box. However, exosome stem cells are affected by changes in external temperature during storage, and the storage devices in the prior art cannot avoid temperature changes, resulting in a significant reduction in storage effect." Therefore, a constant temperature water bath component 2 and a homogenization component 3 are specifically proposed.
[0038] Thermostatic water bath component 2;
[0039] This component primarily employs a constant-temperature water bath to maintain the temperature of the storage box. The water bath chamber 17 inside the water bath tank 9 is where the water is held and the temperature is maintained. The support plate 10 is the component that holds the tank 4. If the air temperature drops, causing a decrease in the temperature of the water inside the water bath tank 9, the temperature sensor 13 will detect it immediately and control the heater 12 via the controller 14 and cable 15. The heater 12, through the heating rod 11, controls the water temperature to rise back to the predetermined temperature, thus ensuring that the inside of the water bath remains at a suitable temperature, guaranteeing the activity of the stem cell exosomes.
[0040] Homogenization component 3:
[0041] The homogenization component 3 includes a holding structure and a homogenization structure. The sealing cap 1 and the jar 4 are the parts that directly hold the stem cells. The cross-shaped slot and pin 5 at the bottom of the jar 4 are the connecting transmission structure, which is achieved through the motor 8 and the rotating shaft 7. This allows the jar 4 to rotate at a uniform speed inside the water bath, making the heating of the jar 4 more uniform.
[0042] It should be noted that, in this document, relational terms such as "first" and "second" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. The above description is merely a preferred embodiment of this utility model, but the scope of protection of this utility model is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the scope of the technology disclosed in this utility model, based on the technical solution and inventive concept of this utility model, should be included within the scope of protection of this utility model.
Claims
1. A stem cell exosome preservation device comprising a sealing cap (1), characterized in that, Also include: The constant temperature water bath assembly (2) includes a water bath tank (9), the side wall of the water bath tank (9) is provided with a heating rod (11), one side of the heating rod (11) is butt jointed with a heater (12), the inside of the water bath tank (9) is plug-in installed with a temperature sensor (13), one side of the temperature sensor (13) is butt jointed with a controller (14), the controller (14) and the heater (12) are connected and installed with a cable (15).
2. The stem cell exosome preservation device of claim 1, wherein, One side of the water bath tank (9) is provided with a shelf plate (10), and the inside of the water bath tank (9) is provided with a water bath bin (17).
3. The stem cell exosome preservation device of claim 2, wherein, The inside of the water bath bin (17) is filled with pure water.
4. The stem cell exosome preservation device of claim 2, wherein, Also include: The holding assembly includes a jar (4) butt jointed on one side of the sealing cover (1), and the inside of the jar (4) is provided with a holding bin (16).
5. The stem cell exosome preservation device of claim 4, wherein, The inside of the holding bin (16) holds stem cell exosomes, and the jar (4) is placed and installed on the surface of the shelf plate (10).
6. The stem cell exosome preservation device of claim 4, wherein, Also include: The homogenization assembly (3) includes a slot (5) butt jointed on one side of the jar (4), the inside of the slot (5) is butt jointed with a pin (6), one side of the pin (6) is butt jointed with a rotating shaft (7), one side of the rotating shaft (7) is butt jointed with a motor (8).
7. The stem cell exosome preservation device of claim 6, wherein, The pin (6) is a cross pin structure, the bottom of the water bath tank (9) is arrayed with a support (18), and the part where the rotating shaft (7) butt joints with the water bath tank (9) is provided with a sealing ring (19).
Citation Information
Patent Citations
Stem cell exosome preservation device
CN214962226U