Dyeing frame for large tissue slices

Abstract

The utility model relates to the field of glass slide dyeing racks, and provides a dyeing rack for a large tissue slice, the dyeing rack comprises a frame body and a support member arranged in the frame body, the frame body is provided with a first side and a second side which are opposite to each other along the width direction, the support member is connected between the first side and the second side, and the first side and the second side are opposite to each other. The frame body is provided with a first side and a second side, one side, facing the second side, of the first side is provided with a first slot, one side, facing the first side, of the second side is provided with a second slot, the first slot and the second slot are symmetrically arranged, the bottom of the frame body is provided with a third slot, and the projection of the first slot on the bottom of the frame body is located in the third slot. And the frame body can be in butt joint with a tool in an automatic dyeing process in a dyeing system, so that the automatic dyeing of the wider glass slide used by a large tissue section is met.

Description

Technical Field

[0001] This application relates to the field of glass slide staining rack technology, and more particularly to a staining rack for large tissue sections. Background Technology

[0002] A glass slide is a thin sheet of glass-like material used to generate phase difference. A slide staining rack is an important tool used for staining slides made from specimens or animal and plant specimens. The slide staining rack can hold or store microscope slides so as to store staining liquid and immerse the slides during the staining process.

[0003] In actual medical testing, multiple slides are placed on a staining rack, which is then immersed in staining solution to stain the slides. In existing techniques, staining racks are only suitable for staining standard slides (25mm wide). However, in practical applications, steel staining racks are mostly used for slides suitable for large tissue sections (40mm-50mm wide). Steel staining racks are difficult to integrate with the tools in automated staining processes, while manual staining is time-consuming and labor-intensive. Utility Model Content

[0004] In order to solve the above-mentioned technical problems, or at least partially solve the above-mentioned technical problems, this application provides a staining rack for large tissue sections.

[0005] This application provides a staining rack for large tissue sections, including a frame and a support member disposed within the frame. The frame has a first side and a second side opposite to each other along its width direction. The support member is connected between the first side and the second side. A first slot is provided on the side of the first side facing the second side, and a second slot is provided on the side of the second side facing the first side. The first slot and the second slot are symmetrically arranged. A third slot is provided at the bottom of the frame, and the projection of the first slot on the bottom of the frame is located within the third slot.

[0006] Optionally, multiple first slots and multiple second slots are provided, with the multiple first slots distributed at intervals along the length direction of the frame, and the multiple first slots and multiple second slots are arranged in a one-to-one correspondence.

[0007] Optionally, the frame includes two bottom beams, two middle beams, two top beams, and two side plates that are arranged opposite each other along its width direction. The bottom beams, the middle beams, and the top beams are spaced apart along the height direction of the frame and are all connected between the two side plates.

[0008] Both side plates are provided with openings for the flow of dyeing liquid.

[0009] Optionally, the first slot is formed between the top beam and the middle beam, and the second slot is formed between the top beam and the middle beam.

[0010] Optionally, a plurality of toothed strips are connected between the top beam and the middle beam, and the plurality of toothed strips are spaced apart along the length direction of the frame, with two adjacent toothed strips forming the first slot and the second slot.

[0011] Optionally, the width of the first slot and the second slot is not less than the thickness of the glass slide.

[0012] Optionally, the support member includes a support plate extending from the top beam of the frame to the bottom beam of the frame, and the two sides of the support plate are respectively connected to the two bottom beams, the two middle beams and the two top beams.

[0013] Optionally, the support member includes an upper support rod, a middle support rod, and a lower support rod. The upper support rod, the middle support rod, and the lower support rod all extend along the width direction of the frame. The upper support rod is connected between two top beams, the middle support rod is connected between two middle beams, and the lower support rod is connected between two bottom beams.

[0014] Optionally, a plurality of toothed blocks are formed on the bottom beam, the plurality of toothed blocks are spaced apart along the length direction of the bottom beam, and two adjacent toothed blocks and the portion of the bottom beam connecting them form the third slot.

[0015] Optionally, the distance between the first slot and the second slot is 42mm-52mm.

[0016] The technical solution provided in this application has the following advantages compared with the prior art:

[0017] The staining rack for large tissue sections provided in this application embodiment is stable and not prone to tilting due to the frame and the support connecting the first and second sides of the frame. A first slot on the first side and a second slot on the second side ensure stable connection of the slide to the frame when inserted into the first and second slots. A third slot at the bottom of the frame, with the projection of the first slot on the bottom of the frame located within the third slot, allows the slide's bottom to be supported by the third slot after insertion into the first and second slots. This design is suitable for wider slides, and the frame can interface with tools in automated staining processes within a staining system, meeting the requirements for automated staining of wider slides used for large tissue sections. Attached Figure Description

[0018] The accompanying drawings, which are incorporated in and form part of this specification, illustrate embodiments consistent with this application and, together with the description, serve to explain the principles of this application.

[0019] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, for those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0020] Figure 1 This is a top view of a staining rack for large tissue sections according to one embodiment of this application;

[0021] Figure 2 This is a side view of a staining rack for large tissue sections according to one embodiment of this application;

[0022] Figure 3 This is a front view of a staining rack for large tissue sections according to another embodiment of this application.

[0023] Among them, 1. frame; 2. support member; 21. upper support rod; 22. middle support rod; 23. lower support rod; 3. first slot; 4. second slot; 5. bottom beam; 6. middle beam; 7. top beam; 8. side plate; 9. toothed strip. Detailed Implementation

[0024] To better understand the above-mentioned objectives, features, and advantages of this application, the solution of this application will be further described below. It should be noted that, unless otherwise specified, the embodiments and features described in these embodiments can be combined with each other.

[0025] Many specific details are set forth in the following description in order to provide a full understanding of this application, but this application may also be implemented in other ways different from those described herein; obviously, the embodiments in the specification are only some embodiments of this application, and not all embodiments.

[0026] In actual medical testing, multiple slides are placed on a staining rack, which is then immersed in staining solution to stain the slides. In existing techniques, staining racks are only suitable for staining standard slides (75mm long, 25mm wide, and 1mm thick). However, in practical applications, steel staining racks are mostly used for slides suitable for large tissue sections (75mm long, 40-50mm wide, and 0.72mm thick). Steel staining racks are difficult to integrate with automated staining processes in staining systems, while manual staining is time-consuming and labor-intensive.

[0027] Based on this, refer to Figures 1 to 3 As shown, this application provides a staining rack for large tissue sections, including a frame 1 and a support member 2 disposed within the frame 1. The frame 1 has a first side and a second side opposite to each other along its width direction. A first slot 3 is provided on the side of the first side facing the second side, and a second slot 4 is provided on the side of the second side facing the first side. The first slot 3 and the second slot 4 are symmetrically arranged. The two sides of the slide are respectively inserted into the first slot 3 and the second slot 4. A third slot is provided at the bottom of the frame 1. The bottom end of the slide abuts against the third slot. The projection of the first slot 3 on the bottom of the frame 1 is located in the third slot, so that when the slide is inserted to the bottom from the first slot 3 and the second slot 4, it can just abut against the third slot.

[0028] Because the staining rack used for large tissue sections is suitable for wider slides, the distance between the first and second sides is relatively large, about 40mm-60mm. The support 2 is connected between the first and second sides, making the whole more stable and preventing the staining rack from tilting to one side or even falling over.

[0029] The staining rack for large tissue sections provided in this application embodiment is stable and not prone to tilting due to the frame 1 and the support 2 connecting the first and second sides of the frame 1. A first slot 3 on the first side and a second slot 4 on the second side ensure that the slide is stably connected to the frame 1 when inserted into the first slot 3 and the second slot 4. A third slot at the bottom of the frame 1, with the projection of the first slot 3 on the bottom of the frame 1 located within the third slot, allows the bottom of the slide to be supported by the third slot after insertion into the first slot 3 and the second slot 4. This design is suitable for wider slides, and the frame 1 can interface with tools in automated staining processes within a staining system, satisfying the automated staining requirements for wider slides used for large tissue sections.

[0030] In some embodiments, such as Figure 1 and Figure 2 As shown, there are multiple first slots 3 and multiple second slots 4. The multiple first slots 3 are distributed at intervals along the length direction of the frame 1. The multiple first slots 3 and multiple second slots 4 are arranged in a one-to-one correspondence, so that multiple wider glass slides can be inserted into the multiple first slots 3 and multiple second slots 4, which can meet the requirements of mass glass slide staining.

[0031] In some embodiments, such as Figure 2As shown, the frame 1 includes two bottom beams 5, two middle beams 6, two top beams 7, and two side plates 8 arranged opposite each other along its width direction. The bottom beams 5, middle beams 6, and top beams 7 are spaced apart along the height direction of the frame 1 and are all connected between the two side plates 8. Each side plate 8 has an opening for the flow of dyeing liquid. When the frame 1 is immersed in dyeing liquid, the dyeing liquid can flow fully between the two bottom beams 5, two middle beams 6, two top beams 7, and two side plates 8, and the glass slides inserted into the first slot 3 and the second slot 4 can be dyed evenly.

[0032] In some embodiments, a first slot 3 is formed between the top beam 7 and the middle beam 6, and a second slot 4 is formed between the top beam 7 and the middle beam 6. That is, there is no slot between the middle beam 6 and the bottom beam 5, which is a hollow structure, making it easier for the dyeing liquid to flow relative to the frame 1.

[0033] In some embodiments, the first slot 3 and the second slot 4 are specifically implemented as follows: a plurality of toothed strips 9 are connected between the top beam 7 and the middle beam 6, and the plurality of toothed strips 9 are distributed at intervals along the length direction of the frame 1, with two adjacent toothed strips 9 forming the first slot 3 and the second slot 4. That is to say, the bottom of the first slot 3 and the second slot 4 is a hollow structure, which allows the slide to fully contact the staining liquid and facilitates the all-round staining of the slide.

[0034] In some embodiments, the width of the first slot 3 and the second slot 4 is not less than the thickness of the slide. In practical applications, the width of the first slot 3 and the second slot 4 is slightly greater than the thickness of the slide to avoid squeezing the slide and causing damage to large tissue sections or the slide itself, and to allow the staining liquid to enter the gap between the slide and the sidewall of the first slot 3 (second slot 4), so that the slide can be stained from all directions.

[0035] In some embodiments, such as Figure 2 As shown, the support member 2 includes a support plate that extends from the top beam 7 of the frame 1 to the bottom beam 5 of the frame 1. The two sides of the support plate are connected to two bottom beams 5, two middle beams 6, and two top beams 7, respectively. The support plate is heavier and has better stability, thus improving the stability of the frame 1.

[0036] In some embodiments, such as Figure 3 As shown, the support member 2 includes an upper support rod 21, a middle support rod 22, and a lower support rod 23. All three extend along the width of the frame 1. The upper support rod 21 connects to the two top beams 7, the middle support rod 22 connects to the two middle beams 6, and the lower support rod 23 connects to the two bottom beams 5. Each of the upper support rod 21, middle support rod 22, and lower support rod 23 has a hollow structure between adjacent members to facilitate the flow of dyeing liquid.

[0037] In some embodiments, a plurality of toothed blocks are formed on the bottom beam 5, the plurality of toothed blocks are spaced apart along the length direction of the bottom beam 5, and two adjacent toothed blocks and the portion of the bottom beam 5 connecting the two form a third slot.

[0038] In some embodiments, the distance between the first slot 3 and the second slot 4 is 42mm-52mm. Preferably, the distance between the first slot 3 and the second slot 4 is 40mm or 50mm, which is suitable for the width of the slides used for large tissue sections in current experiments.

[0039] It should be noted that, in this document, relational terms such as "first" and "second" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0040] The above description is merely a specific embodiment of this application, enabling those skilled in the art to understand or implement this application. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of this application. Therefore, this application is not to be limited to the embodiments described herein, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A staining rack for large bulk tissue sections, characterized in that, The frame (1) has opposite first and second sides along its width direction, and a support member (2) is connected between the first and second sides, one side of the first side facing the second side is provided with a first slot (3), one side of the second side facing the first side is provided with a second slot (4), the first slot (3) and the second slot (4) are symmetrically arranged, and the bottom of the frame (1) is provided with a third slot, and the projection of the first slot (3) on the bottom of the frame (1) is located in the third slot. The frame (1) includes two bottom beams (5), two middle beams (6), two top beams (7) arranged opposite along its width direction, and two side plates (8) arranged opposite along its length direction, the bottom beams (5), the middle beams (6) and the top beams (7) are spaced apart along the height direction of the frame (1) and are connected between the two side plates (8), and the two side plates (8) are each provided with an opening for the flow of dyeing liquid. The support member (2) includes a support plate member, the support plate member extends from the top beam (7) of the frame (1) to the bottom beam (5) of the frame (1), and the two sides of the support plate member are connected with the two bottom beams (5), the two middle beams (6) and the two top beams (7) respectively. Alternatively, the support member (2) includes an upper support rod member (21), a middle support rod member (22) and a lower support rod member (23), the upper support rod member (21), the middle support rod member (22) and the lower support rod member (23) all extend along the width direction of the frame (1), the upper support rod member (21) is connected between the two top beams (7), the middle support rod member (22) is connected between the two middle beams (6), and the lower support rod member (23) is connected between the two bottom beams (5).

2. The staining rack for large bulk tissue sections of claim 1, wherein, The first slot (3) and the second slot (4) are each provided with a plurality of first slots (3), and the plurality of first slots (3) are spaced apart along the length direction of the frame (1), and the plurality of first slots (3) and the plurality of second slots (4) are arranged one by one.

3. The staining rack for large bulk tissue sections of claim 1, wherein, The first slot (3) is formed between the top beam (7) and the middle beam (6), and the second slot (4) is formed between the top beam (7) and the middle beam (6).

4. The staining rack for large bulk tissue sections of claim 3, wherein, The top beam (7) and the middle beam (6) are connected with a plurality of tooth-shaped strips (9), the plurality of tooth-shaped strips (9) are spaced apart along the length direction of the frame (1), and adjacent two tooth-shaped strips (9) form the first slot (3) and the second slot (4).

5. The staining rack for large bulk tissue sections of claim 1, wherein, The slot width of the first slot (3) and the second slot (4) is not less than the thickness of the slide glass.

6. The staining rack for large bulk tissue sections of claim 1, wherein, The bottom beam (5) is formed with a plurality of tooth blocks, the plurality of tooth blocks are spaced apart along the length direction of the bottom beam (5), and adjacent two tooth blocks and the part of the bottom beam (5) connected therebetween form the third slot.

7. The staining rack for large bulk tissue sections of claim 1, wherein, The distance between the first slot (3) and the second slot (4) is 42-52 mm.

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