Centrifugal extraction separator for biological medicine

By introducing filtration and cleaning components into a centrifugal extraction and separation machine for biomedicine, the problem of cleaning brushes affecting normal operation and drug purity has been solved, enabling secondary filtration and convenient cleaning of the drug solution, thus improving pharmaceutical quality.

CN223995605UActive Publication Date: 2026-03-17BEIJING YUANDIAN CRITICAL TECHNOLOGY CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-02-12
Publication Date
2026-03-17

AI Technical Summary

Technical Problem

The cleaning brushes of existing centrifugal extraction and separation machines for biopharmaceuticals are designed inside the filter cartridge, which affects the normal centrifugal extraction and separation process, is not easy to replace, and cannot achieve secondary filtration of the drug solution, thus affecting the purity of the drug solution and the quality of the pharmaceutical product.

Method used

A centrifugal extraction separator including a filtration component and a cleaning component was designed. The filtration component achieves secondary filtration of the liquid through a two-stage filtration box and a fine filter screen. The cleaning component enables convenient replacement of the cleaning block and cleaning of the filter cartridge through a lifting cylinder and a telescopic rod, avoiding interference with normal operation.

Benefits of technology

It achieves secondary filtration of the medicine solution, improves the purity of the medicine solution, avoids impurity residue, and the cleaning block can be removed from the outside of the filter cartridge for easy replacement and cleaning, ensuring the normal operation of the equipment.

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Abstract

The utility model provides a centrifugal extraction separator for biological medicine, which relates to the technical field of extraction separators and comprises a separator main body, a filter cartridge mounted in the separator main body, a plurality of filter holes formed in the outer side of the filter cartridge, a cartridge cover in threaded connection with the top of the filter cartridge, and a feed hopper mounted at the top of the cartridge cover, the cleaning assembly is arranged at the top of the filter cartridge and comprises a workbench, a supporting frame, a lifting air cylinder, a telescopic rod, a mounting barrel and a cleaning block. According to the centrifugal extraction separator for the biological medicine, liquid medicine can be secondarily filtered through the filtering assembly, fine impurities in the liquid medicine can be conveniently filtered out, the purity of the extracted liquid medicine is improved, the pharmaceutical quality is prevented from being affected by impurity residues, the interior of the filtering barrel can be cleaned through the cleaning assembly, and after cleaning is completed, the filtering barrel can be cleaned through the cleaning assembly. The cleaning block and the telescopic rod can be moved out of the filter cartridge, so that the normal centrifugal extraction liquid medicine separation work of the filter cartridge is not influenced, and the cleaning block can be conveniently replaced.
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Description

Technical Field

[0001] This utility model relates to the field of extraction and separation machine technology, specifically a centrifugal extraction and separation machine for biomedicine. Background Technology

[0002] Biomedical extraction is a process involving the extraction, separation, and purification of bioactive compounds from natural products. These natural products can come from various sources such as plants, animals, and microorganisms, while the target compounds typically include pharmaceutical, health product ingredients, and other high-value bioactive molecules. Centrifugal extraction is a novel extraction technology that uses a centrifugal extractor as its core equipment. It is characterized by high efficiency, continuous operation, and environmental friendliness, and it is widely used in many fields of biomedicine.

[0003] Regarding centrifugal extraction separators for biopharmaceutical applications, a search revealed a publication (application number) CN217645981U. This centrifugal extraction separator, through the cooperation of a second motor, rotating tube, rotating rod, and cleaning brush, can automatically clean the filter cartridge, avoiding the tedious process of disassembling and cleaning the cartridge. The height of the cleaning brush can be adjusted through the cooperation of the rotating rod, third motor, screw, and drive block, allowing the brush to switch between cleaning and stop modes and increasing its cleaning range for more comprehensive cleaning of the filter cartridge. However, the cleaning brush is designed inside the filter cartridge and cannot be removed after cleaning. The rotating rod and cleaning brush being inside the filter cartridge also affect normal centrifugal extraction and separation operations, and the internal location of the cleaning brush makes replacement inconvenient. Utility Model Content

[0004] The technical problem to be solved by this utility model is to provide a centrifugal extraction and separation machine for biomedicine. The filter component can perform secondary filtration of the drug solution, which can easily filter out the fine impurities in the drug solution, improve the purity of the drug solution after extraction, and avoid the impact of impurity residue on the quality of pharmaceuticals. The cleaning component can clean the inside of the filter cylinder. After cleaning, the cleaning block and telescopic rod can be moved out of the filter cylinder without affecting the normal centrifugal extraction and separation of the drug solution. It also makes it easy to replace the cleaning block.

[0005] The technical problem to be solved by this utility model is achieved by the following technical solution:

[0006] A centrifugal extraction and separation machine for biomedicine includes: a separator body, a filter cylinder installed inside the separator body, multiple filter holes opened on the outside of the filter cylinder, a cylinder cover threaded to the top of the filter cylinder, a feed hopper installed on the top of the cylinder cover, a cleaning assembly disposed on the top of the filter cylinder, the cleaning assembly including: a worktable, a support frame, a lifting cylinder, a telescopic rod, an installation cylinder and a cleaning block, and a filter assembly disposed at the bottom of the separator body, the filter assembly including: a drain pipe, a secondary filter box, a pad block, a filter plate, a fine filter screen, a handle and a collection box.

[0007] Preferably, a workbench is installed at the bottom of the separator body, a support frame is installed on one side of the top of the workbench, a lifting cylinder is installed on the top of the support frame, a telescopic rod is connected to the bottom output end of the lifting cylinder, an installation cylinder is installed at the bottom of the telescopic rod, and a cleaning block is installed at the bottom of the installation cylinder.

[0008] Preferably, the separator body has drain pipes installed on both sides of the bottom, a secondary filter box at the bottom of the drain pipes, pads installed on both sides inside the secondary filter box, a filter plate on the top of the pads, a fine filter screen installed inside the filter plate, handles installed on both sides of the top of the filter plate, and a collection box at the bottom of the filter plate.

[0009] Preferably, a limiting frame is installed on the top of the separator body, and a bearing that is rotatably connected to the filter cylinder is installed at the top of the limiting frame. A servo motor is installed at the bottom of the separator body, and a motor shaft is connected to the top output end of the servo motor. The motor shaft passes through the separator body and is connected to the filter cylinder. The motor shaft and the separator body are rotatably connected by a sealed bearing.

[0010] Preferably, the telescopic rod has an external thread layer on its bottom outer side, and the mounting cylinder has an internal thread layer that is threadedly connected to the external thread layer on its inner wall.

[0011] Preferably, a mounting base is installed on the workbench, and through holes are opened on both sides of the outer end of the mounting base. A fixing screw is provided inside each of the through holes. Screw holes are opened on both sides of the outer end of the separator body, and a handle is installed on the outside of the fixing screw.

[0012] Preferably, a connecting cylinder is installed at the bottom of the filter cartridge, and three reinforcing rubber rings adapted to the motor shaft are installed inside the connecting cylinder, and the motor shaft is movably connected to the reinforcing rubber rings.

[0013] The beneficial effects of this utility model are:

[0014] (1) The filter assembly of this utility model can perform secondary filtration of the medicine liquid, which makes it easier to filter out the fine impurities in the medicine liquid, improve the purity of the medicine liquid after extraction, and avoid the residue of impurities affecting the quality of the medicine.

[0015] (2) The cleaning component of this utility model can clean the inside of the filter cylinder. After cleaning, the cleaning block and telescopic rod can be moved out of the filter cylinder without affecting the normal centrifugal extraction and separation of the filter cylinder. It also makes it easy to replace the cleaning block. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the overall structure of this utility model.

[0017] Figure 2 This is a schematic cross-sectional view of the present invention.

[0018] Figure 3 This is a schematic diagram of the connection structure between the separator body and the mounting base of this utility model.

[0019] Figure 4 This is a schematic diagram of the disassembled structure of the cleaning block and telescopic rod of this utility model.

[0020] Figure 5 This is a schematic diagram of the mounting base structure of this utility model.

[0021] Figure 6 For the present utility model Figure 2 Enlarged diagram of point A in the middle.

[0022] Figure 7 This is a top view cross-sectional diagram of the filter plate of this utility model.

[0023] Figures 1-7 Components: 1. Separator body; 101. Filter cylinder; 102. Filter holes; 103. Cylinder cover; 104. Feed hopper; 105. Limit frame; 106. Bearing; 107. Servo motor; 108. Motor shaft; 2. Worktable; 201. Support frame; 202. Lifting cylinder; 203. Telescopic rod; 204. Mounting cylinder; 205. Cleaning block; 206. External thread layer; 3. Mounting base; 301. Through hole; 302. Fixing screw; 303. Handle; 4. Connecting cylinder; 401. Reinforcing rubber ring; 5. Drain pipe; 501. Secondary filter box; 502. Pad; 503. Filter plate; 504. Fine filter screen; 505. Handle; 506. Collection box. Detailed Implementation

[0024] The technical solutions in the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of this application without creative effort are within the scope of protection of this application.

[0025] The present application will now be described in detail with reference to the accompanying drawings and specific embodiments.

[0026] Example

[0027] like Figures 1-7 As shown, a centrifugal extraction and separation machine for biomedicine includes: a separator body 1, a filter cylinder 101 installed inside the separator body 1, multiple filter holes 102 opened on the outside of the filter cylinder 101, a cylinder cover 103 threadedly connected to the top of the filter cylinder 101, a feed hopper 104 installed on the top of the cylinder cover 103, a cleaning assembly set on the top of the filter cylinder 101, the cleaning assembly including: a workbench 2, a support frame 201, a lifting cylinder 202, a telescopic rod 203, an installation cylinder 204 and a cleaning block 205, and a filter assembly set at the bottom of the separator body 1, the filter assembly including: a drain pipe 5, a secondary filter box 501, a pad block 502, a filter plate 503, a fine filter screen 504, a handle 505 and a collection box 506.

[0028] The workbench 2 is equipped with a mounting base 3. The mounting base 3 has through holes 301 on both sides of its outer end. Each through hole 301 is equipped with a fixing screw 302. The separator body 1 has screw holes on both sides of its outer end. A handle 303 is installed on the outside of the fixing screw 302.

[0029] When using the separator body 1, place the separator body 1 inside the mounting base 3, so that the screw holes on both sides of the outer end of the separator body 1 are directly opposite the through holes 301 on both sides of the outer end of the mounting base 3. At this time, insert the fixing screw 302 from the through hole 301 into the screw hole, and grasp the handle 303 to rotate the fixing screw 302, so that the fixing screw 302 is tightened inside the screw hole, thereby fixing the separator body 1 and the mounting base 3 together, that is, the separator body 1, the mounting base 3 and the worktable 2 are used as a whole.

[0030] The separator body 1 has a limit frame 105 installed on the top, and a bearing 106 that is rotatably connected to the filter cartridge 101 is installed inside the limit frame 105. A servo motor 107 is installed at the bottom of the separator body 1, and a motor shaft 108 is connected to the top output end of the servo motor 107. The motor shaft 108 passes through the separator body 1 and is connected to the filter cartridge 101. The motor shaft 108 and the separator body 1 are rotatably connected by a sealed bearing.

[0031] After the separator body 1 is installed securely, when extracting and removing impurities from the liquid medicine, the liquid medicine is poured from the feed hopper 104 into the filter cylinder 101. At this time, the servo motor 107 is started. The servo motor 107 drives the motor shaft 108 to rotate the filter cylinder 101 and generate centrifugal force. Under the action of centrifugal force, the liquid medicine inside the filter cylinder 101 is thrown out from multiple filter holes 102 and falls into the separator body 1. Through the action of centrifugal force, impurities in the liquid medicine can be quickly extracted and removed.

[0032] During the rotation of the filter cartridge 101, the top of the filter cartridge 101 is limited by the limiting frame 105, and the normal rotation of the filter cartridge 101 is ensured by the bearing 106.

[0033] The separator body 1 has drain pipes 5 installed on both sides of the bottom. A secondary filter box 501 is installed at the bottom of the drain pipes 5. Pads 502 are installed on both sides inside the secondary filter box 501. A filter plate 503 is installed on the top of the pads 502. A fine filter screen 504 is installed inside the filter plate 503. Handles 505 are installed on both sides of the top of the filter plate 503. A collection box 506 is installed at the bottom of the filter plate 503.

[0034] After the extracted and purified medicinal liquid falls into the separator body 1, it can be discharged from the outside of the separator body 1 through the drain pipe 5. That is, the medicinal liquid is discharged from the drain pipe 5 into the secondary filter box 501, so that the medicinal liquid falls on the filter plate 503. The medicinal liquid can be filtered a second time through the fine filter screen 504 inside the filter plate 503, which makes it easier to filter out the fine impurities in the medicinal liquid, improve the purity of the extracted medicinal liquid, and avoid the impurities remaining and affecting the quality of the pharmaceutical.

[0035] During use, the filter plate 503 is supported by the pad 502 to ensure that it is placed flat. When there are many impurities filtered on the fine filter screen 504, the filter plate 503 can be lifted out of the secondary filter box 501 by grasping the handle 505 to apply force. This makes it easier to clean the impurities on the fine filter screen 504 and rinse it clean to prevent the mesh of the fine filter screen 504 from becoming clogged and affecting normal filtration.

[0036] The filter cartridge 101 has a connecting cylinder 4 installed at its bottom. Inside the connecting cylinder 4 are three reinforcing rubber rings 401 that are adapted to the motor shaft 108. The motor shaft 108 is movably connected to the reinforcing rubber rings 401. After the filter cartridge 101 is used, many impurities are filtered inside. The filter cartridge 101 can be grabbed and pulled upwards. When the filter cartridge 101 is under force, the motor shaft 108 disengages from the reinforcing rubber rings 401 inside the connecting cylinder 4, so that the connecting cylinder 4 is separated from the motor shaft 108. The filter cartridge 101 can be lifted and pulled out from the limiting frame 105 and the bearing 106. Then, the cylinder cover 103 is rotated to loosen and disassembled from the top of the filter cartridge 101, making it easy to pour out and clean the impurities inside the filter cartridge 101.

[0037] After cleaning the impurities from the filter cartridge 101, insert the filter cartridge 101 into the separator body 1 from the limiting frame 105. That is, the connecting cylinder 4 at the bottom of the filter cartridge 101 can be inserted into the motor shaft 108. At this time, the connecting cylinder 4 can be sleeved together with the motor shaft 108 through the reinforcing rubber ring 401. The reinforcing rubber ring 401 can increase the stability of the connection between the connecting cylinder 4 and the motor shaft 108.

[0038] Among them, the bottom of the separator body 1 is equipped with a workbench 2, the top side of the workbench 2 is equipped with a support frame 201, the top of the support frame 201 is equipped with a lifting cylinder 202, the bottom output end of the lifting cylinder 202 is connected to a telescopic rod 203, the bottom of the telescopic rod 203 is equipped with an installation cylinder 204, and the bottom of the installation cylinder 204 is equipped with a cleaning block 205.

[0039] When the filter cartridge 101 needs to be cleaned after use, loosen and remove the top cover 103 of the filter cartridge 101. At this time, start the lifting cylinder 202 to drive the telescopic rod 203 to move downward, so that the telescopic rod 203 pushes the mounting cylinder 204 and the cleaning block 205 downward into the filter cartridge 101. This can drive the cleaning block 205 to move up and down inside the filter cartridge 101 and pour clean water into the filter cartridge 101. The cleaning block 205 can clean the inside of the filter cartridge 101. After cleaning, the cleaning block 205 and the telescopic rod 203 can be removed from the outside of the filter cartridge 101 without affecting the normal centrifugal extraction and separation of the medicine in the filter cartridge 101, and it is also convenient to replace the cleaning block 205.

[0040] The size of the cleaning block 205 is the same as the inner diameter of the filter cylinder 101, meaning that the cleaning block 205 can fit against the inner wall of the filter cylinder 101, ensuring that the filter cylinder 101 can be cleaned thoroughly.

[0041] The telescopic rod 203 has an external thread layer 206 on its bottom outer side, and the mounting cylinder 204 has an internal thread layer that is threaded to the external thread layer 206. When the cleaning block 205 is in use, it is installed and used together with the telescopic rod 203 through the mounting cylinder 204. That is, the internal thread layer on the inner wall of the mounting cylinder 204 is threaded to the external thread layer 206 on the bottom outer side of the telescopic rod 203, so that the mounting cylinder 204 and the telescopic rod 203 can be flexibly installed. When the cleaning block 205 is worn, it is easy to disassemble and replace it with a new one.

[0042] Working principle:

[0043] When using the separator body 1, place the separator body 1 inside the mounting base 3, so that the screw holes on both sides of the outer end of the separator body 1 are directly opposite the through holes 301 on both sides of the outer end of the mounting base 3. At this time, insert the fixing screw 302 from the through hole 301 into the screw hole, and grasp the handle 303 to rotate the fixing screw 302, so that the fixing screw 302 is tightened inside the screw hole, thereby fixing the separator body 1 and the mounting base 3 together. That is, the separator body 1, the mounting base 3 and the worktable 2 are used as a whole. After the separator body 1 is installed securely, when extracting and removing impurities from the liquid medicine, pour the liquid medicine from the feed hopper 104 into the filter cylinder 101. At this time, start the servo motor 107 to work. The servo motor 107 drives the motor shaft 108 to drive the filter cylinder 101 to rotate and generate centrifugal force. Under the action of centrifugal force, the liquid medicine inside the filter cylinder 101 is thrown out from multiple filter holes 102 and falls into the separator body 1. Through the action of centrifugal force, the impurities in the liquid medicine can be quickly extracted and removed.

[0044] After the extracted and purified medicinal liquid falls into the separator body 1, it can be discharged from the outside of the separator body 1 through the drain pipe 5. That is, the medicinal liquid is discharged from the drain pipe 5 into the secondary filter box 501, so that the medicinal liquid falls on the filter plate 503. The medicinal liquid can be filtered a second time through the fine filter screen 504 inside the filter plate 503, which makes it easier to filter out the fine impurities in the medicinal liquid, improve the purity of the extracted medicinal liquid, and avoid the impurities remaining and affecting the quality of the pharmaceutical.

[0045] When the filter cartridge 101 needs to be cleaned after use, loosen and remove the top cover 103 of the filter cartridge 101. At this time, start the lifting cylinder 202 to drive the telescopic rod 203 to move downward, so that the telescopic rod 203 pushes the mounting cylinder 204 and the cleaning block 205 downward into the filter cartridge 101. This can drive the cleaning block 205 to move up and down inside the filter cartridge 101 and pour clean water into the filter cartridge 101. The cleaning block 205 can clean the inside of the filter cartridge 101. After cleaning, the cleaning block 205 and the telescopic rod 203 can be removed from the outside of the filter cartridge 101 without affecting the normal centrifugal extraction and separation of the medicine in the filter cartridge 101, and it is also convenient to replace the cleaning block 205.

[0046] In the above embodiments, the descriptions of each embodiment have different focuses. For parts not described in detail in a certain embodiment, please refer to the relevant descriptions in other embodiments.

[0047] The above provides a detailed description of a centrifugal extraction and separation machine for biomedicine provided in the embodiments of this application. Specific examples have been used to illustrate the principles and implementation methods of this application. The description of the above embodiments is only for the purpose of helping to understand the technical solutions and core ideas of this application. Those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features. These modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application.

Claims

1. A centrifugal extractor for bio-pharmaceuticals, characterized in that, Include: Separation machine body (1); Filter cartridge (101) installed inside the separation machine body (1); A plurality of filter holes (102) are opened on the outside of the filter cartridge (101); The cartridge cover (103) is threadedly connected to the top of the filter cartridge (101); The feed hopper (104) is installed on the top of the cartridge cover (103); A cleaning assembly is provided on the top of the filter cartridge (101), which comprises a workbench (2), a support frame (201), a lifting cylinder (202), a telescopic rod (203), an installation cylinder (204) and a cleaning block (205); A filter assembly is provided at the bottom of the separation machine body (1), which comprises a drain pipe (5), a secondary filter box (501), a cushion block (502), a filter plate (503), a fine filter screen (504), a handle (505) and a collection box (506).

2. The centrifugal extractive separator for biomedical use according to claim 1, characterized in that, The workbench (2) is installed at the bottom of the separation machine body (1), one side of the top of the workbench (2) is provided with a support frame (201), the top of the support frame (201) is provided with a lifting cylinder (202), the bottom output end of the lifting cylinder (202) is connected with a telescopic rod (203), the bottom of the telescopic rod (203) is provided with an installation cylinder (204), and the bottom of the installation cylinder (204) is provided with a cleaning block (205).

3. The centrifugal extractive separator for biomedical use according to claim 1, characterized in that, The drain pipe (5) is installed at the bottom of the separation machine body (1), the drain pipe (5) is provided with a secondary filter box (501) at the bottom, the secondary filter box (501) is provided with a cushion block (502) on both sides inside, the cushion block (502) is provided with a filter plate (503) at the top, the filter plate (503) is provided with a fine filter screen (504) inside, the filter plate (503) is provided with a handle (505) on both sides at the top, and the filter plate (503) is provided with a collection box (506) at the bottom.

4. The centrifugal extractive separator for biomedical use according to claim 1, characterized in that, The separation machine body (1) is provided with a limiting frame (105) at the top, a bearing (106) is installed at the top end inside the limiting frame (105) and connected with the filter cartridge (101) in rotation, a servo motor (107) is installed at the bottom of the separation machine body (1), the top output end of the servo motor (107) is connected with a motor shaft (108), the motor shaft (108) penetrates the separation machine body (1) and is connected with the filter cartridge (101), and the motor shaft (108) and the separation machine body (1) are connected in rotation through a sealing bearing.

5. The centrifugal extractive separator for biomedical use according to claim 2, characterized in that, The bottom outside of the telescopic rod (203) is provided with an outer thread layer (206), and the inner wall of the installation cylinder (204) is provided with an inner thread layer (206) which is threadedly connected with the outer thread layer (206).

6. The centrifugal extractive separator for biomedical use according to claim 2, characterized in that, The workbench (2) is provided with a mounting seat (3), a through hole (301) is formed on both sides of the outer end of the mounting seat (3), a fixed screw rod (302) is arranged inside the through hole (301), screw holes are formed on both sides of the outer end of the separation machine body (1), and a handle (303) is arranged outside the fixed screw rod (302).

7. The centrifugal extractive separator for biomedical use according to claim 4, characterized in that, The filter cartridge (101) is provided with a connecting cylinder (4) at the bottom, and three reinforced rubber rings (401) are arranged in the connecting cylinder (4) and matched with the motor shaft (108).

Citation Information

Patent Citations

  • Centrifugal extraction separator for biological medicine

    CN217645981U