Mouth-dissolving film preparation equipment for medical health care products

Abstract

The utility model provides oral soluble film making equipment for medical health care products, which relates to the technical field of medical health care products and comprises a support frame, and the top of the support frame is provided with the oral soluble film making equipment. The oral soluble film preparation equipment comprises a PET film unwinding module, a PET film roller passing module, a tension module, a coating module, a thickness detection module, a constant temperature box body module, an infrared lamp drying module, a process deviation rectification module, a film preparation surface defect CCD detection module, a medical film separation module, a tension swing rod module, a PET film winding module and a medical film winding module. The tension of the film is monitored and adjusted in real time through the tension module; the coating module can accurately control the coating thickness and width of the slurry; the thickness detection module feeds back film thickness information in real time, closed-loop control is formed, it is guaranteed that the thickness of the oral dissolving film is uniform, then the stability of the medicine dissolving rate is guaranteed, meanwhile, the constant-temperature box module and the infrared lamp drying module are combined, and the production efficiency and the film forming quality are improved.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical and health product technology, and in particular to an oral dissolution film forming device for pharmaceutical and health products. Background Technology

[0002] As a novel drug delivery system, rapid oral dissolving films for pharmaceuticals offer significant advantages such as rapid dissolution, ease of administration, and improved patient compliance. They are particularly ideal for children, the elderly, and individuals with swallowing difficulties. Traditional Chinese medicine (TCM) oral dissolving films, due to their fewer side effects and stable efficacy, are gaining increasing attention in the market. However, the manufacturing process of rapid oral dissolving films for pharmaceuticals places extremely high demands on the precision, stability, and automation of the equipment. Currently, China relies heavily on imported equipment in this field, resulting in a low level of domestic production. In particular, the development of rapid oral dissolving films for TCM is still in the research and exploration stage, with no related products yet successfully launched. To improve the absorption efficiency of TCM, achieve precise dosage control, and reduce gastrointestinal irritation, developing a pharmaceutical oral dissolving film preparation device with independent intellectual property rights has become a crucial task. This is of great significance for solving core scientific problems, overcoming technical difficulties, and promoting technological progress and industrial upgrading in my country's high-end pharmaceutical equipment sector.

[0003] China's research and industrialization of pharmaceutical oral dissolution film preparation devices started relatively late, and there is a significant gap in technology and industrialization compared to foreign countries. However, according to market research data, the domestic market size for pharmaceutical oral dissolution films is expected to grow significantly from US$300 million in 2021 to US$1 billion in 2028, with an average annual compound growth rate of over 15%. This rapidly growing market demand has strongly promoted the technological innovation and industrialization process of domestic pharmaceutical oral dissolution film preparation devices. Currently, domestic research on pharmaceutical oral dissolution film preparation devices mainly focuses on key technology areas such as high-precision coating, intelligent control, and online monitoring, and the technological level is gradually improving. However, the industrialization of domestic pharmaceutical oral dissolution film preparation devices is still in its early stages. Although some companies have launched commercial products, the overall production capacity and technological level need to be further improved. These companies have accumulated preliminary experience in technology research and development, production processes, and quality control, and are gradually building a relatively complete technology system and industrial chain.

[0004] Currently available oral dissolution film forming equipment suffers from poor film thickness uniformity due to insufficient precision in the coating process, which in turn affects the stability of drug dissolution rate. At the same time, existing equipment has shortcomings in drying technology, which can easily cause degradation of active ingredients in traditional Chinese medicine during the drying process, reducing product quality. Moreover, some equipment lacks an effective online quality detection mechanism, making it difficult to detect film thickness, drug distribution uniformity, and surface defects in real time, resulting in a large number of unqualified products during the production process. Utility Model Content

[0005] This utility model proposes a film-making equipment for oral dissolving films used in pharmaceuticals and health products. By organically combining multiple technologies such as tension control technology, thickness detection closed-loop control technology, infrared drying technology, constant temperature oven baking technology, and CCD surface defect detection technology, it achieves high-precision coating and drying, intelligent production control, online quality inspection, and green manufacturing process, thereby solving the problems mentioned in the background technology.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: a film-forming device for oral dissolving films used in pharmaceuticals and health products, comprising a support frame, with an oral dissolving film forming device mounted on the top of the support frame. The oral dissolving film forming device includes a PET film unwinding module, a PET film roller module, a tension module, a coating module, a thickness detection module, a constant temperature chamber module, an infrared drying module, a process correction module, a film surface defect CCD detection module, a pharmaceutical film separation module, a tension swing arm module, a PET film winding module, and a pharmaceutical film winding module. The PET film unwinding module, tension module, coating module, constant temperature chamber module, process correction module, film surface defect CCD detection module, pharmaceutical film separation module, tension swing arm module, PET film winding module, and pharmaceutical film winding module are sequentially and fixedly connected to the top of the support frame from left to right. The PET film roller module is fixedly installed on the right side of the PET film unwinding module, the thickness detection module is fixedly installed on the right side of the coating module, and the infrared drying module is fixedly installed on the right side of the constant temperature chamber module.

[0007] Preferably, the tension module includes two connecting frames, which are respectively fixedly connected to the front and rear sides of the top of the support frame. A first motor is fixedly connected to the top of the inner surface of the connecting frame, and a first screw is fixedly connected to the output shaft of the first motor. A threaded slider is threadedly connected to the outer surface of the first screw, and a tension roller is rotatably connected to the middle of the opposite surfaces of the two threaded sliders.

[0008] Preferably, a support platform is fixedly connected to the right side of the lower inner surface of the coating module, and a V-shaped groove is formed on the right side of the upper inner surface of the coating module. The inner wall of the V-shaped groove has three grooves, and a second motor is fixedly connected to the inner wall of the middle groove. The output shaft of the second motor is fixedly connected to a second screw.

[0009] Preferably, the outer surface of the second screw is threaded with a V-shaped scraper, the V-shaped scraper is slidably connected to the inner surface of the V-shaped groove and its bottom end extends to the top of the support platform, and two guide posts are fixedly connected to the front and rear sides of the top of the V-shaped scraper, the outer surface of the guide posts is slidably connected to the inner surface of the groove.

[0010] Preferably, the constant temperature chamber module includes a conductive chamber, which is fixedly connected to the top of the support frame. An annular groove is provided inside the conductive chamber, and several air outlet pipes are provided on the upper and lower sides of the inner surface of the annular groove, which extend to the inner side of the conductive chamber.

[0011] Preferably, air inlet holes are provided on the top left and right sides of the annular groove, the top of the air inlet holes extends through to the top of the conductive box, a dustproof net is fixedly connected to the upper part of the inner wall of the air inlet hole, a fan is fixedly connected to the middle part of the inner wall of the air inlet hole, and an electric heating element is fixedly connected to the lower part of the inner wall of the air inlet hole.

[0012] Due to the adoption of the above technical solution, the technological progress achieved by this utility model compared to the prior art is as follows:

[0013] 1. In this utility model, the tension module, coating module, and thickness detection module work together to achieve precise adjustment of PET film tension and high-precision coating of pharmaceutical and health product slurries. The tension module monitors and adjusts the film tension in real time to ensure stable operation; the coating module can accurately control the coating thickness and width of the slurry; the thickness detection module provides real-time feedback of film thickness information, forming a closed-loop control to ensure uniform thickness of the oral dissolution film, thereby ensuring the stability of the drug dissolution rate. At the same time, the constant temperature chamber module and the infrared lamp drying module are combined with the intelligent production control system to monitor and control parameters such as temperature, humidity, and drying rate in real time. Under the premise of ensuring that the active ingredients of traditional Chinese medicine are not degraded, the wet film is quickly dried into a high-quality solid film, improving production efficiency and film quality.

[0014] 2. In this utility model, the CCD detection module for film surface defects is combined with online quality inspection technology. Utilizing technologies such as machine vision, spectral analysis, and three-dimensional measurement, it performs real-time detection of film thickness, drug distribution uniformity, and surface defects. Once a defective product is detected, an alarm is triggered and feedback is provided for adjustment, effectively reducing the generation of unqualified products, reducing raw material waste, and significantly improving the controllability of product quality. In addition, the equipment adopts green manufacturing processes, selects biodegradable and highly biocompatible film-forming materials, optimizes the water-based solvent system, reduces the use of organic solvents, reduces production energy consumption and environmental pollution, and researches recyclable or degradable packaging materials, promoting the sustainable development of pharmaceutical oral dissolution film manufacturing. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the oral dissolution film forming equipment of this utility model;

[0016] Figure 2 This is a schematic diagram of the tension module of this utility model;

[0017] Figure 3This is a cross-sectional structural diagram of the coating module of this utility model;

[0018] Figure 4 This is a cross-sectional structural diagram of the constant temperature chamber module of this utility model.

[0019] Legend: 1. Support frame; 2. Oral soluble film forming equipment; 21. PET film unwinding module; 22. PET film passing module; 23. Tension module; 231. Connecting frame; 232. First motor; 233. First screw; 234. Threaded slider; 235. Tension roller; 24. Coating module; 241. Support platform; 242. V-shaped chute; 243. Second motor; 244. Second screw; 245. V-shaped scraper; 246. Guide column; 25. 26. Thickness detection module; 26. Constant temperature chamber module; 261. Conductive chamber; 262. Annular groove; 263. Air outlet pipe; 264. Air inlet hole; 265. Dustproof net; 266. Fan; 267. Heating element; 27. Infrared lamp drying module; 28. Process correction module; 29. ​​Film surface defect CCD detection module; 210. Pharmaceutical film separation module; 211. Tension swing arm module; 212. PET film winding module; 213. Pharmaceutical film winding module. Detailed Implementation

[0020] To better understand the above-mentioned objectives, features, and advantages of this utility model, the present utility model will be further described below with reference to the accompanying drawings and embodiments. It should be noted that, unless otherwise specified, the embodiments and features described in these embodiments can be combined with each other.

[0021] Many specific details are set forth in the following description in order to provide a full understanding of the present invention. However, the present invention may also be implemented in other ways different from those described herein. Therefore, the present invention is not limited to the specific embodiments disclosed in the following specification.

[0022] Example 1: As Figure 1As shown, this utility model provides a technical solution: it includes a support frame 1, and an oral soluble film forming device 2 is arranged on the top of the support frame 1. The oral soluble film forming device 2 includes a PET film unwinding module 21, a PET film roller passing module 22, a tension module 23, a coating module 24, a thickness detection module 25, a constant temperature chamber module 26, an infrared lamp drying module 27, a process correction module 28, a film surface defect CCD detection module 29, a pharmaceutical film separation module 210, a tension swing arm module 211, a PET film winding module 212, and a pharmaceutical film winding module 213. The PET film unwinding... Modules 21, 23, 24, 26, 28, 29, 20, 20, 210, 211, 212, 213 are fixedly connected to the top of the support frame 1 from left to right. The PET film unwinding module 22 is fixedly installed on the right side of the PET film unwinding module 21. The thickness detection module 25 is fixedly installed on the right side of the coating module 24. The infrared drying module 27 is fixedly installed on the right side of the constant temperature chamber module 26.

[0023] The overall effect achieved by Embodiment 1 is as follows: During operation, the PET film unwinding module 21 unwinds at a uniform speed. After being supported by the PET film roller module 22 and the tension is detected and adjusted by the tension module 23, the coating module 24 uniformly coats the pharmaceutical and health product slurry onto the PET film. The coating parameters are adjustable. The thickness detection module 25 monitors the film thickness in real time and automatically adjusts or alarms when abnormalities occur. The coated pharmaceutical film enters the constant temperature chamber module 26 along with the PET film for drying. After drying, the process correction module 28 corrects the deviation path, and the film surface defect CCD detection module 29 detects surface defects. After passing the inspection, the pharmaceutical film separation module 210 separates the PET film from the pharmaceutical film. The PET film is directly wound up by the PET film winding module 212. After the tension of the pharmaceutical film is adjusted again by the tension swing bar module 211, the pharmaceutical film is wound up by the pharmaceutical film winding module 213.

[0024] Example 2: Figure 2 As shown, this utility model provides a technical solution: the tension module 23 includes two connecting frames 231, which are fixedly connected to the front and rear sides of the top of the support frame 1 respectively. A first motor 232 is fixedly connected to the top of the inner surface of the connecting frame 231. A first screw 233 is fixedly connected to the output shaft of the first motor 232. A threaded slider 234 is threadedly connected to the outer surface of the first screw 233. A tension roller 235 is rotatably connected to the middle of the opposite face of the two threaded sliders 234.

[0025] The effect achieved by the entire embodiment 2 is as follows: During operation, the tension roller 235 monitors the tension of the PET film in real time through the installation of sensors, and feeds the signal back to the control system. When the tension is too high or too low, the control system starts the first motor 232, which drives the first screw 233 to rotate, causing the threaded slider 234 to move up and down along the first screw 233, thereby driving the tension roller 235 to rise or fall, adjusting the tension of the PET film, ensuring that the PET film maintains a stable operating state in subsequent coating and other processes, avoiding film wrinkles or breakage due to unstable tension, and providing a guarantee for high-precision coating.

[0026] Example 3: As Figure 3 As shown, this utility model provides a technical solution: a support platform 241 is fixedly connected to the right side of the lower surface of the inner wall of the coating module 24, a V-shaped groove 242 is opened on the right side of the upper surface of the inner wall of the coating module 24, three grooves are opened on the inner wall of the V-shaped groove 242, a second motor 243 is fixedly connected to the inner wall of the middle groove, a second screw 244 is fixedly connected to the output shaft of the second motor 243, a V-shaped scraper 245 is threadedly connected to the outer surface of the second screw 244, the V-shaped scraper 245 is slidably connected to the inner surface of the V-shaped groove 242 and its bottom end extends to the top of the support platform 241, two guide posts 246 are fixedly connected to the front and rear sides of the top of the V-shaped scraper 245, and the outer surface of the guide posts 246 is slidably connected to the inner surface of the groove;

[0027] The overall effect achieved in Embodiment 3 is as follows: the PET film coated with slurry passes through the support platform 241. After the second motor 243 is started, it drives the second screw 244 to rotate. The threaded transmission causes the V-shaped scraper 245 to slide up and down in the V-shaped groove 242. By adjusting the distance between the V-shaped scraper 245 and the support platform 241, the thickness of the slurry coating is precisely controlled. During the coating process, the guide column 246 slides in the groove to ensure the stability and accuracy of the movement of the V-shaped scraper 245, so that the slurry can be uniformly coated on the PET film, meeting the coating precision requirements of pharmaceutical oral dissolution films.

[0028] Example 4: Figure 4As shown, this utility model provides a technical solution: the constant temperature chamber module 26 includes a conductive chamber 261, which is fixedly connected to the top of the support frame 1. An annular groove 262 is opened inside the conductive chamber 261. Several air outlet pipes 263 are opened on the upper and lower sides of the inner surface of the annular groove 262. The air outlet pipes 263 penetrate to the inner side of the conductive chamber 261. Air inlet holes 264 are opened on the left and right sides of the top of the annular groove 262. The top of the air inlet hole 264 penetrates to the top of the conductive chamber 261. A dustproof net 265 is fixedly connected to the upper part of the inner wall of the air inlet hole 264. A fan 266 is fixedly connected to the middle part of the inner wall of the air inlet hole 264. An electric heating element 267 is fixedly connected to the lower part of the inner wall of the air inlet hole 264.

[0029] The overall effect achieved in Embodiment 4 is as follows: After the fan 266 is started, outside air is drawn in through the air inlet 264. The air is first filtered through the dust filter 265 to prevent dust and other impurities from entering. Then the air is heated by the electric heating element 267. The heated air enters the annular groove 262 and is then blown evenly through the air outlet 263 onto the medical film inside the guide box 261. The adhesive-like medical film attached to the PET film is dried with hot air. By controlling the airflow of the fan 266 and the heating power of the electric heating element 267, the temperature and airflow inside the box can be precisely adjusted, so that the medical film can be quickly dried into a solid film under suitable conditions. At the same time, in conjunction with the infrared lamp drying module, the drying efficiency and quality are further improved, ensuring that the active ingredients of traditional Chinese medicine are not destroyed.

[0030] The working principle of the entire equipment is as follows: First, the PET film is threaded onto the conveyor belt according to the conveyor belt diagram. During operation, the PET film unwinding module 21 unwinds the film at a certain speed. The PET film roller module 22 provides support for the PET film, allowing it to smoothly enter the tension module 23. The tension module 23 detects and adjusts the tension of the PET film in real time. Subsequently, the coating module 24 evenly coats the pharmaceutical or health product slurry onto the PET film. The coating thickness and width parameters can be set and adjusted in the module. The PET film coated with slurry continues to be conveyed forward. The thickness detection module 25 performs real-time thickness detection on the coated pharmaceutical or health product film. When the thickness exceeds the specification, the coating module 24 is automatically adjusted or an alarm is triggered. The coated pharmaceutical film adheres to the PET film and enters the constant temperature chamber module 26, where it is dried by the combined action of hot air and infrared lamp drying modules 27. Under the action of the process, the PET film is quickly dried into a solid film. After drying, the pharmaceutical film leaves the constant temperature chamber module 26 along with the PET film and enters the process correction module 28 for route correction to ensure accurate operation. After route correction, the PET film and pharmaceutical film enter the film surface defect CCD detection module 29, which takes pictures of the pharmaceutical film surface to identify defects such as bubbles and poor coating size. After CCD detection, the film enters the pharmaceutical film separation module 210 to separate the PET film and pharmaceutical film. After separation, the PET film is directly connected to the PET film winding module 212 for winding, while the pharmaceutical film is tensioned again by the tension swing bar module 211 and enters the pharmaceutical film winding module 213 with a smaller tension to complete winding. The equipment adopts green manufacturing process, selects biodegradable materials, optimizes production process, and reduces energy consumption and environmental pollution.

[0031] The above description is merely a preferred embodiment of the present utility model and is not intended to limit the present utility model in any other way. Any person skilled in the art may make changes or modifications to the above-disclosed technical content to create equivalent embodiments for application in other fields. However, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present utility model without departing from the technical solution of the present utility model shall still fall within the protection scope of the technical solution of the present utility model.

Claims

1. A film-forming device for oral dissolving films used in pharmaceuticals and health products, characterized in that: The application relates to a support frame (1) provided with a mouth dissolving film manufacturing device (2) at the top of the support frame (1), wherein the mouth dissolving film manufacturing device (2) comprises a PET film unwinding module (21), a PET film passing roller module (22), a tension module (23), a coating module (24), a thickness detection module (25), a constant temperature box body module (26), an infrared lamp drying module (27), a process deviation rectifying module (28), a film surface defect CCD detection module (29), a medical film separating module (210), a tension swing lever module (211), a PET film winding module (212) and a medical film winding module (213), the PET film unwinding module (21), the tension module (23), the coating module (24), the constant temperature box body module (26), the process deviation rectifying module (28), the film surface defect CCD detection module (29), the medical film separating module (210), the tension swing lever module (211), the PET film winding module (212) and the medical film winding module (213) are sequentially fixedly connected at the top of the support frame (1) from left to right, the PET film passing roller module (22) is fixedly installed at the right side of the PET film unwinding module (21), the thickness detection module (25) is fixedly installed at the right side of the coating module (24), and the infrared lamp drying module (27) is fixedly installed at the right side of the constant temperature box body module (26).

2. The medical health care product dissolving film equipment according to claim 1, characterized in that: The tension module (23) comprises two connecting frames (231) which are fixedly connected at the top of the support frame (1) at the front and back sides respectively, a first motor (232) is fixedly connected to the top of the inner surface of the connecting frame (231), a first screw rod (233) is fixedly connected to the output shaft of the first motor (232), a threaded sliding block (234) is threadedly connected to the outer surface of the first screw rod (233), and one tension roller (235) is rotatably connected to the middle of the opposite surfaces of the two threaded sliding blocks (234).

3. The medical health care product dissolving film equipment according to claim 1, characterized in that: A supporting table (241) is fixedly connected to the lower surface right side of the inner wall of the coating module (24), a V-shaped sliding groove (242) is formed in the upper surface right side of the inner wall of the coating module (24), three grooves are formed in the inner wall of the V-shaped sliding groove (242), a second motor (243) is fixedly connected to the inner wall of the middle groove, and a second screw rod (244) is fixedly connected to the output shaft of the second motor (243).

4. The medical health care product dissolving film equipment according to claim 3, characterized in that: A V-shaped scraper (245) is threadedly connected to the outer surface of the second screw rod (244), the V-shaped scraper (245) is slidingly connected to the inner surface of the V-shaped sliding groove (242) and penetrates through the top of the supporting table (241) at the bottom end, two guide columns (246) are fixedly connected to the top front and back sides of the V-shaped scraper (245), and the outer surface of the guide column (246) is slidingly connected with the inner surface of the groove.

5. The medical health care product dissolving film equipment according to claim 1, characterized in that: The thermostat body module (26) includes a through box (261) fixedly connected to the top of the support frame (1), an annular groove (262) is formed in the inside of the through box (261), a plurality of air outlet pipes (263) are formed on the inner surface of the annular groove (262) on both sides of the top and bottom, and the air outlet pipes (263) penetrate to the inside of the through box (261).

6. The medical health care product dissolving film equipment according to claim 5, characterized in that: Air inlet holes (264) are formed on both sides of the top and bottom of the annular groove (262), the top end of the air inlet hole (264) penetrates to the top of the through box (261), a dust screen (265) is fixedly connected to the top of the inner wall of the air inlet hole (264), a fan (266) is fixedly connected to the middle of the inner wall of the air inlet hole (264), and an electric heating element (267) is fixedly connected to the bottom of the inner wall of the air inlet hole (264).

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