Ultrasonic crushing heat preservation device

Abstract

The utility model discloses an ultrasonication heat preservation device, which belongs to the technical field of cell disruption devices and comprises a disruption machine body, an energy converter is arranged at the top of the disruption machine body, an amplitude-change pole penetrating into the disruption machine body is mounted at the bottom of the energy converter, a horizontally arranged partition plate is arranged on the inner wall of the disruption machine body, and the partition plate is arranged on the outer wall of the disruption machine body. A lifting table is arranged on the partition plate, a water containing tank with an opening in the top end is installed on the lifting table, a cover plate is installed at the top of the water containing tank, a cavity structure extending downwards into the water containing tank is arranged in the middle of the cover plate, and a low-temperature cooling circulating pump is installed at the bottom end of the inner wall of the crusher body; the input end and the output end of the low-temperature cooling circulating pump are communicated with the water containing tank through a water inlet pipe and a water outlet pipe respectively. The cavity structure is used for placing the culture cup, and the cavity structure and the culture cup are separately arranged, so that a sample and the culture cup can be taken down together after the cells are broken.

Description

TECHNICAL FIELD

[0001] The utility model relates to cell crushing device technical field, specifically to an ultrasonic crushing heat preservation device. BACKGROUND

[0002] The ultrasonic wave crushing appearance in prior art mostly carries out the cooling of the whole space in the crusher body, since the space in the crusher body is larger, more air needs to be cooled, therefore, higher energy needs to be consumed, and the culture cup is directly placed on the lifting platform, lacks the device for limiting and protecting the culture cup, the culture cup is easy to fall off from the lifting platform under the vibration of the amplitude lever or external force, thereby causing the culture cup to be damaged and the sample to be discarded.

[0003] There is also a cooling device for local cooling of the sample in prior art, but when using, the sample is directly poured into the placing cavity of the device for cell crushing, the device does not separately use the culture cup to hold the sample, thereby causing the sample to be inconvenient to pour out from the placing cavity after the cell crushing is completed, and since the placing cavity needs to be cleaned after being used once, the device needs to be taken down for cleaning when cleaning the placing cavity, which is very inconvenient. SUMMARY

[0004] The utility model discloses in order to solve the prior art exists the problem, provide an ultrasonic crushing heat preservation device.

[0005] In order to achieve the above-mentioned purpose, the utility model discloses the technical scheme that adopts: an ultrasonic crushing heat preservation device, including the crusher body, the crusher body top is provided with the transducer, the bottom of transducer is installed with the amplitude lever that penetrates to the crusher body inside, the inner wall of crusher body is equipped with the partition that arranges horizontally, be equipped with the lifting platform on the partition, install the water tank of top opening on the lifting platform, the top of water tank is installed with the cover plate, the middle part of cover plate has a cavity structure that extends to the water tank, the bottom end of the inner wall of crusher body is installed with low temperature cooling circulating pump, the input and output of low temperature cooling circulating pump are linked with water tank through water inlet pipe and water outlet pipe respectively.

[0006] In the above technical scheme, when the device is working normally, the transducer can convert electrical energy into acoustic energy, the amplitude lever can transfer the ultrasonic wave amplitude generated by the transducer to the sample to promote cell rupture, the partition is used to separate the low temperature cooling circulating pump and the lifting platform in the vertical direction, and can support the lifting platform, the lifting platform is used to drive the water tank and the culture cup to lift, when the culture cup needs to be placed in the cavity structure, the amplitude lever can be adjusted to extend into the culture cup, thereby facilitating the amplitude lever to crush the cells in the culture cup.

[0007] The cavity structure is used for placing the culture cup, since the cavity structure is arranged separately from the culture cup, after the cell crushing is completed, the sample can be taken together with the culture cup, the step of pouring the sample into the cavity structure for cell crushing and then pouring the sample from the cavity structure back to the culture cup is saved, and meanwhile, after the culture cup is used, the culture cup can be taken out alone for cleaning, so that the culture cup does not need to be taken together with the cover plate and the water tank.

[0008] Since the amplitude rod generates a large amount of heat during work, the heat is transmitted to the sample in the culture cup, the sample is warmed, and the sample is damaged, the cooling liquid loaded in the water tank can cool the culture cup and the sample, so that the sample is always kept in a certain temperature range, after the cooling liquid in the water tank cools the culture cup and the sample, the heat of the cooling liquid is increased, the cooling liquid after being warmed can flow out from the water tank through the water outlet pipe, and then flows into the low-temperature cooling circulating pump for cooling, meanwhile, the low-temperature cooling circulating pump can deliver the cooling liquid after being cooled to the water tank through the water inlet pipe, so that the temperature in the water tank is kept stable in a certain range.

[0009] Further, the inner wall of the cavity structure is cylindrical.

[0010] In the above technical solution, the cavity structure can be other shapes that can be matched with the culture cup.

[0011] Further, the cover plate is detachably mounted on the water tank by bolts, and the cover plate can be detached from the water tank when the cooling liquid needs to be replaced, so that the cooling liquid in the water tank is conveniently replaced.

[0012] Further, the inner wall of the cavity structure is provided with an inner lining for fixing the culture cup and avoiding shaking of the culture cup, since the amplitude rod generates noise when crushing the cells in the sample, the inner lining can absorb part of the noise to some extent, so as to reduce the noise generated when the cells are crushed.

[0013] Further, the water tank is bonded to the top end of the lifting table, and the water tank is fixed on the lifting table by the above connection mode, so as to avoid falling of the water tank.

[0014] Further, the electronic valve is installed on the water inlet pipe and the water outlet pipe.

[0015] In the above technical solution, the electronic valve is used for controlling the flow of the cooling liquid in the water inlet pipe and the water outlet pipe.

[0016] Further, a temperature sensor extending into the water tank is threadedly connected to the cover plate, and an output end of the temperature sensor is electrically connected to an input end of the low-temperature cooling circulating pump.

[0017] In the above technical solution, the temperature sensor is used for monitoring the temperature of the cooling liquid in the water tank, so that the user can conveniently adjust the low-temperature cooling circulating pump.

[0018] Further, the display screen is installed on the crusher body.

[0019] In the above technical solution, the display screen is used for displaying the temperature tested by the operation panel and the temperature sensor, so that the user can conveniently operate the device.

[0020] Further, the partition plate is provided with two avoiding holes for the water inlet pipe and the water outlet pipe to pass through, respectively.

[0021] In the above technical solution, the avoiding holes can limit the water inlet pipe and the water outlet pipe, so as to avoid the water inlet pipe and the water outlet pipe from being scattered randomly.

[0022] Further, the fan is installed on the two side walls of the crusher body, and the fan is at the same height position as the low-temperature cooling circulating pump.

[0023] In the above technical solution, the fan is used for discharging the heat generated by the low-temperature cooling circulating pump from the crusher body, so as to realize heat dissipation of the low-temperature cooling circulating pump.

[0024] Compared with the prior art, the present application has the following advantages:

[0025] The ultrasonic crushing and heat preservation device, the cavity structure is used for placing the culture cup, because the cavity structure and the culture cup are separately arranged, therefore, after the cell crushing is completed, the sample can be taken together with the culture cup, the step of pouring the sample into the cavity structure for cell crushing and then pouring the sample from the cavity structure back into the culture cup is saved, and after the culture cup is used, it can be taken out alone for cleaning, so that the culture cup, the cover plate and the water tank do not need to be taken down together.

[0026] The ultrasonic crushing and heat preservation device, the cooling liquid loaded in the water tank can cool the culture cup and the sample, so that the sample can always be kept within a certain temperature range, after the cooling liquid in the water tank cools the culture cup and the sample, the heat of the cooling liquid itself will increase, the cooling liquid after being heated can flow out from the water tank through the water outlet pipe, and then flow into the low-temperature cooling circulating pump for cooling, and at the same time, the low-temperature cooling circulating pump can deliver the cooled cooling liquid into the water tank through the water inlet pipe again, so as to realize circulation, so as to ensure that the temperature in the water tank can also be stabilized within a certain range.

[0027] The ultrasonic crushing and heat preservation device, the inner wall of the cavity structure is provided with an inner lining, which can fix the culture cup and avoid shaking of the culture cup, and can also absorb some noise. BRIEF DESCRIPTION OF DRAWINGS

[0028] Fig. 1 It is a sectional view structure schematic diagram of the utility model.

[0029] Fig. 2 It is a sectional view structure schematic diagram of the water tank of the utility model.

[0030] Fig. 3 It is a three-dimensional structure schematic diagram of the cover plate of the utility model.

[0031] In the figure: 1, crusher body; 2, transducer; 3, amplitude bar; 4, partition; 5, lifting platform; 6, water tank; 7, cover plate; 8, cavity structure; 9, temperature sensor; 10, low-temperature cooling circulating pump; 11, water inlet pipe; 12, water outlet pipe; 13, bolt; 14, inner lining; 15, electronic valve; 16, display screen; 17, fan; 18, culture cup. DETAILED DESCRIPTION

[0032] The technical scheme of the utility model will be described clearly and completely below in combination with the drawings in the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by the ordinary skilled in the art without creative labor belong to the scope of protection of the utility model.

[0033] Please refer to Figs. 1 to 3 The ultrasonic crushing heat preservation device in the embodiment comprises a crusher body 1, the crusher body 1 is provided with a transducer 2 at the top, the transducer 2 is provided with an amplitude bar 3 penetrating into the inside of the crusher body 1 at the bottom, a horizontally arranged partition 4 is arranged on the inner wall of the crusher body 1, the partition 4 is provided with a lifting platform 5, the lifting platform 5 is a manual lifting platform, the lifting platform 5 is provided with a water tank 6 with an open top, the water tank 6 is provided with a cover plate 7 at the top, the cover plate 7 has a cavity structure 8 extending downward into the water tank 6 in the middle, a low-temperature cooling circulating pump 10 is arranged at the bottom end of the inner wall of the crusher body 1, and the input end and the output end of the low-temperature cooling circulating pump 10 are connected with the water tank 6 in communication through a water inlet pipe 11 and a water outlet pipe 12.

[0034] In the above technical scheme, when the device is normally working, the transducer 2 can convert electric energy into acoustic energy, the amplitude transformer 3 can transfer the ultrasonic wave amplitude generated by the transducer 2 to the sample to promote cell rupture, the partition plate 4 is used to separate the low-temperature cooling circulating pump 10 from the lifting platform 5 in the vertical direction, and can support the lifting platform 5, the lifting platform 5 is used to drive the water tank 6 and the culture cup 18 to ascend and descend, when the culture cup 18 needs to be placed into the cavity structure 8, the adjusting lifting platform 5 can make the amplitude transformer 3 extend into the culture cup 18, so that the amplitude transformer 3 can break the cells in the culture cup 18; the transducer 2 and the amplitude transformer 3 can be the same type of product in the commercially available ultrasonic cell crusher.

[0035] The cavity structure 8 is used to place the culture cup 18, since the cavity structure 8 is separately arranged from the culture cup 18, after the cell rupture is completed, the sample can be taken together with the culture cup 18, which saves the step of pouring the sample into the cavity structure 8 for cell rupture, and then pouring the sample from the cavity structure 8 back into the culture cup 18, and after the culture cup 18 is used, it can be taken out alone for cleaning, so that the culture cup 18 does not need to be taken together with the cover plate 7 and the water tank 6.

[0036] Since the amplitude transformer 3 generates a large amount of heat during work, and the heat is transferred to the sample in the culture cup 18, the sample is heated, which causes the sample to be damaged, and the cooling liquid in the water tank 6 can cool the culture cup 18 and the sample, so that the sample always maintains within a certain temperature range, after the cooling liquid in the water tank 6 cools the culture cup 18 and the sample, the heat of the cooling liquid itself increases, the heated cooling liquid can flow out of the water tank 6 through the water outlet pipe 12, and then flow into the low-temperature cooling circulating pump 10 for cooling, and at the same time, the low-temperature cooling circulating pump 10 can deliver the cooled cooling liquid to the water tank 6 through the water inlet pipe 11 again, so that the temperature in the water tank 6 is also stabilized within a certain range.

[0037] Further, the inner wall of the cavity structure 8 is cylindrical, the cavity structure 8 can be other shapes that can be matched with the culture cup 18, for example, the culture cup 18 is square, and the cavity structure 8 is also square; the inner wall of the cavity structure 8 is provided with an inner lining 14, the inner lining 14 is fitted with the outer wall of the culture cup 18 to fix the culture cup 18, so as to avoid the culture cup 18 from shaking under the action of the amplitude transformer 3, the inner lining can be an elastic or flexible heat-conducting material, which can bind the culture cup without affecting heat exchange; at the same time, since the amplitude transformer 3 generates noise when breaking the cells in the sample, the noise is transmitted to the surrounding of the culture cup 18 through the culture cup 18, the inner lining 14 can absorb part of the noise to reduce the noise generated during cell rupture.

[0038] Further, the cover plate 7 is detachably mounted on the water tank 6 by bolts 13. With the above structure, the cover plate 7 can be detached from the water tank 6 when the coolant needs to be replaced, thereby facilitating the replacement of the coolant in the water tank 6. The cover plate 7 can be made of a plate material with high heat conduction efficiency, such as a graphene plate, an iron plate or a copper plate.

[0039] Further, the water tank 6 is bonded to the top end of the lifting platform 5. With the above connection mode, the water tank 6 can be fixed on the lifting platform 5, avoiding falling of the water tank 6.

[0040] Further, the cover plate 7 is threaded with a temperature sensor 9 extending into the water tank 6. The output end of the temperature sensor 9 is electrically connected to the input end of the low-temperature cooling circulating pump 10. The temperature sensor 9 is used to monitor the temperature of the coolant in the water tank 6, thereby facilitating the user to make corresponding adjustment to the low-temperature cooling circulating pump 10.

[0041] Further, the crusher body 1 is provided with a display screen 16. The display screen 16 is used to display the temperature tested by the operation panel and the temperature sensor 9, thereby facilitating the user to operate the device.

[0042] Further, the water inlet pipe 11 and the water outlet pipe 12 are both provided with electronic valves 15. The electronic valves 15 are used to control the flow of the coolant in the water inlet pipe 11 and the water outlet pipe 12. The partition plate 4 is provided with two avoiding holes for the water inlet pipe 11 and the water outlet pipe 12 to pass through. The avoiding holes can limit the water inlet pipe 11 and the water outlet pipe 12, avoiding random scattering of the water inlet pipe 11 and the water outlet pipe 12.

[0043] The crusher body 1 is provided with two fans 17 on the two side walls. The fans 17 are at the same height position as the low-temperature cooling circulating pump 10. The fans 17 are used to discharge the heat generated by the low-temperature cooling circulating pump 10 from the crusher body 1, thereby achieving heat dissipation of the low-temperature cooling circulating pump 10.

[0044] Working mode: when the cells need to be broken, pour the cell sample into the culture cup 18, then put the culture cup 18 into the cavity structure 8, then drive the water tank 6, the cover plate 7 and the culture cup 18 to rise by the lifting platform 5, so that the amplitude rod 3 can enter the culture cup 18, then start the device, the transducer 2 drives the amplitude rod 3 to work, the amplitude rod 3 breaks the cells, and a large amount of heat is generated at the same time, and at the same time, the electronic valve 15, the low-temperature cooling circulating pump 10 and the fan 17 are opened, the low-temperature cooling circulating pump 10 sends the refrigerated cooling liquid into the water tank 6 through the water inlet pipe 11, the cooling liquid cools the cover plate 7, so that a temperature difference is formed between the cover plate 7 and the culture cup 18, which is beneficial to the heat exchange between the cover plate 7 and the culture cup 18, thereby reducing the heat of the culture cup 18, so that the cells in the culture cup 18 are kept at a certain temperature, and the used cooling liquid flows back to the low-temperature cooling circulating pump 10 through the water outlet pipe 12, and the low-temperature cooling circulating pump 10 cools the cooling liquid again, so that the circulation is realized, and the fan 17 drives the air flow to discharge the heat generated by the low-temperature cooling circulating pump 10; when the cell breaking is completed, the culture cup 18 can be directly taken out from the cavity structure 8, so that the sample transfer and the culture cup 18 cleaning are facilitated.

[0045] Although the embodiments of the utility model have been shown and described, it can be understood by those skilled in the art that various changes, modifications, replacements and variations can be made to these embodiments without departing from the principles and spirits of the utility model, and the scope of the utility model is defined by the appended claims and their equivalents.

Claims

1. An ultrasonic crushing and heat preservation device, comprising a crusher body (1), characterized in that, A transducer (2) is provided on the top of the crusher body (1). A variable amplitude rod (3) is installed at the bottom of the transducer (2) and extends into the interior of the crusher body (1). A horizontally arranged partition (4) is provided on the inner wall of the crusher body (1). A lifting platform (5) is provided on the partition (4). A water tank (6) with an open top is installed on the lifting platform (5). A cover plate (7) is installed on the top of the water tank (6). A cavity structure (8) extending downward into the water tank (6) is provided in the middle of the cover plate (7). A low-temperature cooling circulation pump (10) is installed at the bottom of the inner wall of the crusher body (1). The input end and output end of the low-temperature cooling circulation pump (10) are connected to the water tank (6) through an inlet pipe (11) and an outlet pipe (12), respectively.

2. The ultrasonic crushing and heat preservation device according to claim 1, characterized in that, The inner wall of the cavity structure (8) is cylindrical.

3. The ultrasonic crushing and heat preservation device according to claim 1, characterized in that, The cover plate (7) is detachably mounted on the water tank (6) by bolts (13).

4. The ultrasonic crushing and heat preservation device according to claim 1, characterized in that, The inner wall of the cavity structure (8) is provided with an inner lining (14).

5. The ultrasonic crushing and heat preservation device according to claim 1, characterized in that, The water tank (6) is attached to the top of the lifting platform (5).

6. The ultrasonic crushing and heat preservation device according to claim 1, characterized in that, Electronic valves (15) are installed on both the inlet pipe (11) and the outlet pipe (12).

7. The ultrasonic crushing and heat preservation device according to claim 1, characterized in that, A temperature sensor (9) with a probe extending into the water tank (6) is threaded onto the cover plate (7), and the output end of the temperature sensor (9) is electrically connected to the input end of the low-temperature cooling circulation pump (10).

8. The ultrasonic crushing and heat preservation device according to claim 1, characterized in that, A display screen (16) is installed on the crusher body (1).

9. The ultrasonic crushing and heat preservation device according to claim 1, characterized in that, The partition (4) has two clearance holes for the water inlet pipe (11) and the water outlet pipe (12) to pass through respectively.

10. The ultrasonic crushing and heat preservation device according to claim 1, characterized in that, Fans (17) are installed on both side walls of the crusher body (1), and the fans (17) and the low temperature cooling circulation pump (10) are at the same height.

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