Colloidal gold double-sample kit with blood / excrement double-mode switching function

Abstract

The utility model relates to the technical field of biological detection, in particular to a colloidal gold double-sample kit with a blood / excrement double-mode switching function, which comprises a switching plate, a connecting block, a switching slide block, a partition plate, a guide component, a filter component and a flow guide component, the connecting block is fixedly installed on the switching plate, a through groove is formed in one side of the main body shell, the connecting block penetrates through the through groove and extends to the outer side of the main body shell, the switching sliding block is fixedly installed on the connecting block, the partition plate is fixedly installed on the main body shell and located in the sample treatment groove, the filtering assembly is arranged in the sample treatment groove, and the flow guide assembly is arranged on the partition plate. By pushing the switching sliding block, the switching sliding block drives the connecting block and the switching plate to move left and right, so that the left side part of the blood sample treatment tank or the right side part of the sample treatment tank for treating excrement is opened respectively, and switching detection of a blood and excrement double-sample mode is completed.

Description

TECHNICAL FIELD

[0001] The utility model relates to biological detection technical field especially, relate to a kind of colloidal gold double sample kit with blood / feces dual-mode switching function. BACKGROUND

[0002] Immune colloidal gold technology is a new type of immune labeling technology using colloidal gold as a tracer marker for antigen-antibody, and immune chromatography colloidal gold technology is a new and relatively simple diagnostic technology, which has been widely used. The basic principle is as follows: a kind of antigen or antibody is labeled with colloidal gold, and the corresponding paired antigen or antibody is coated on the NC membrane of the reagent. When the sample contains the corresponding specific antibody or antigen during detection, the colloidal gold labeled particles and the ligand in the sample combine to form a complex, which is then chromatographed on the NC membrane and captured by the coated antigen or antibody to form a visible detection T line. The presence or absence of the detection line is used to determine the result.

[0003] Existing colloidal gold test kits are mostly designed with single sample type. If different samples need to be detected, the entire device needs to be replaced, which is complicated to operate and has high cost. Although some products attempt to integrate double detection lines, the sample pretreatment and flow path are not physically isolated, which can easily lead to cross contamination. UTILITY MODEL CONTENT

[0004] The utility model aims at providing a kind of colloidal gold double sample kit with blood / feces dual-mode switching function, which solves the problem of existing colloidal gold test kits mostly designed with single sample type. If different samples need to be detected, the entire device needs to be replaced, which is complicated to operate and has high cost. Although some products attempt to integrate double detection lines, the sample pretreatment and flow path are not physically isolated, which can easily lead to cross contamination.

[0005] To achieve the above-mentioned purpose, the utility model provides a kind of colloidal gold double sample kit with blood / feces dual-mode switching function, including main body shell and colloidal gold test strip, the both sides of main body shell are equipped with sample processing groove and detection display groove respectively, the colloidal gold test strip is fixedly installed in main body shell, still include switching device, the switching device includes switching plate, connecting block, switching sliding block, partition plate, guide assembly, filter component and flow guide component, the switching plate is slidably installed in main body shell by guide assembly, the connecting block is fixedly installed on the switching plate, one side of main body shell is equipped with through groove, the connecting block penetrates through through groove, and extends to the outside of main body shell, the switching sliding block is fixedly installed on the connecting block, the partition plate is fixedly installed on main body shell, and located in sample processing groove, the filter component is arranged in sample processing groove, and the flow guide component is arranged on the partition plate.

[0006] The guiding assembly comprises a fixed block and a guiding protrusion, the fixed block is fixedly installed in the main body shell, and a sliding groove is arranged on the fixed block; the guiding protrusion is fixedly installed on the switching plate and is in sliding cooperation with the sliding groove.

[0007] The filtering assembly comprises a filter screen and a filter membrane, the filter membrane and the filter screen are both fixedly installed on the main body shell and are both located in the sample processing groove, and the filter membrane and the filter screen are arranged on the two sides of the partition plate respectively.

[0008] The flow guiding assembly comprises a first flow guiding plate and a second flow guiding plate, the first flow guiding plate and the second flow guiding plate are both fixedly installed on the two sides of the partition plate and are both in contact with the switching plate.

[0009] The main body shell is further provided with an observation window on one side, and the observation window is arranged in the detection display groove.

[0010] The switching slider is pressed by a finger, the switching slider is pushed, the switching slider drives the switching plate to move left and right through the connecting block, when blood is used as a sample, the switching slider is moved to the right side, blood is dropped into the sample processing groove on the left side, after the blood is filtered by the filter membrane, the blood flows to the colloidal gold test strip along the first flow guiding plate, when feces is used as a sample, the switching slider is slid to the left side, and the feces is put into the sample processing groove on the right side, after the feces is filtered by the filter screen, the feces flows into the colloidal gold test strip along the second flow guiding plate, the specific detection principle is that red blood cells are filtered by the filter membrane, plasma enters the colloidal gold marking area, target antigens in the plasma are combined with colloidal gold labeled antibodies to form a compound, the compound is chromatographed to a T line, is captured by a fixed antibody, and color development (such as a red band) is performed, the remaining compound continues to migrate to a C line to develop color, quality control is completed, if the sample is feces, the sample is intercepted by the filter screen, filtrate enters the colloidal gold marking area, target antigens (such as rotavirus antigens) are combined with colloidal gold labeled monoclonal antibodies, the compound is chromatographed to the T line, is captured by a polyclonal antibody to develop color, the remaining compound migrates to the C line to verify effectiveness, and switching detection of the blood and feces double-sample modes is completed. BRIEF DESCRIPTION OF DRAWINGS

[0011] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the drawings needed to be used in the embodiments or the prior art description will be briefly introduced.

[0012] Figure 1It is the whole structure schematic view of a colloidal gold double sample kit with blood / feces double mode switching function.

[0013] Figure 2 It is the structure schematic view of the switching device.

[0014] Figure 3 It is the connection schematic view of the switching plate and the fixed block.

[0015] In the figure: 101 - main body shell, 102 - colloidal gold test strip, 103 - sample processing groove, 104 - detection display groove, 105 - switching plate, 106 - connecting block, 107 - switching slider, 108 - partition plate, 109 - through groove, 110 - fixed block, 111 - guide protrusion, 112 - filter screen, 113 - filter membrane, 114 - first flow guide plate, 115 - second flow guide plate, 116 - observation window, 117 - sliding groove. DETAILED DESCRIPTION

[0016] The embodiments of the utility model are described in detail below, the example of the embodiment is shown in the drawing, the embodiment described below is exemplary, aims at explaining the utility model, and can not be understood as the limitation of the utility model.

[0017] The embodiment of the application is:

[0018] Please refer to Figures 1-3 , Figure 1 It is the whole structure schematic view of a colloidal gold double sample kit with blood / feces double mode switching function, Figure 2 It is the structure schematic view of the switching device, Figure 3 It is the connection schematic view of the switching plate and the fixed block.

[0019] The utility model provides a kind of colloidal gold double sample kit with blood / feces double mode switching function: including main body shell 101 and colloidal gold test strip 102, still including switching device, the switching device includes switching plate 105, connecting block 106, switching slider 107, partition plate 108, guide assembly, filter assembly and flow guide component, the guide assembly includes fixed block 110 and guide protrusion 111, the filter assembly includes filter screen 112 and filter membrane 113, the flow guide component includes first flow guide plate 114 and second flow guide plate 115, the side of the main body shell 101 is also equipped with observation window 116, the foregoing scheme solves the problem that existing colloidal gold kit is mostly designed with single sample type, if different sample needs to be detected, replace the whole device, there is the problem of tedious operation, high cost etc. Although part of product attempts to integrate double detection line, sample pre-treatment and flow path are not physically isolated, and cross contamination problem is prone to occur.

[0020] In the embodiment, the switching slider 107 is pushed to drive the connecting block 106 and the switching plate 105 to move left and right, so that the left part of the sample processing groove 103 for processing blood or the right part of the sample processing groove 103 for processing feces is opened respectively, thereby completing the switching detection of the blood and feces double sample mode.

[0021] The switching plate 105 is slidably installed in the main body shell 101 through a guide assembly, the connecting block 106 is fixedly installed on the switching plate 105, one side of the main body shell 101 is provided with a through slot 109, the connecting block 106 penetrates through the through slot 109 and extends to the outside of the main body shell 101, the switching slider 107 is fixedly installed on the connecting block 106, the partition plate 108 is fixedly installed on the main body shell 101 and located in the sample processing groove 103, the filter assembly is arranged in the sample processing groove 103, the flow guide assembly is arranged on the partition plate 108, the switching plate 105 is a flat plate structure, the connecting block 106 is fused on the switching plate 105, the switching slider 107 is fused on the top of the connecting block 106, and the partition plate 108 is arranged in the middle of the sample processing groove 103. The switching slider 107 is pushed to drive the connecting block 106 and the switching plate 105 to move left and right, so that the left part of the sample processing groove 103 for processing blood or the right part of the sample processing groove 103 for processing feces is opened respectively, thereby completing the switching detection of the blood and feces double sample mode.

[0022] Secondly, the fixed block 110 is fixedly installed in the main body shell 101, and a sliding groove 117 is arranged on the fixed block 110; the guide protrusion 111 is fixedly installed on the switching plate 105 and slidably matched with the sliding groove 117, the fixed block 110 is fused in the main body shell 101, and the guide protrusion 111 is a square structure. The sliding cooperation of the guide protrusion 111 and the fixed block 110 realizes the guiding effect of the switching plate 105.

[0023] Thirdly, the filter membrane 113 and the filter screen 112 are both fixedly installed on the main body shell 101 and located in the sample processing groove 103, and the filter membrane 113 and the filter screen 112 are arranged on the two sides of the partition plate 108 respectively, the filter membrane 113 is a 0.5 μm filter membrane, and the filter screen 112 is a silk screen. The arrangement of the filter membrane 113 and the filter screen 112 facilitates the filtration of blood and feces.

[0024] Again, the first flow guide plate 114 and the second flow guide plate 115 are fixedly installed on both sides of the partition plate 108 and are in contact with the switching plate 105, the first flow guide plate 114 and the second flow guide plate 115 are respectively arranged on the left and right sides of the partition plate 108, and the first flow guide plate 114 and the second flow guide plate 115 are arranged, so as to facilitate the flow guide of blood and feces.

[0025] Finally, the observation window 116 is arranged in the detection display groove 104, and the observation window 116 is made of transparent plastic material, so as to facilitate the observation of the detection result.

[0026] In the embodiment, when in use, the finger is pressed on the switching slider 107, the switching slider 107 is pushed to drive the switching plate 105 to move left and right through the connecting block 106, when blood is used as a sample, the switching slider 107 is moved to the right side, blood is dropped into the sample processing groove 103 on the left side, and after the blood is filtered by the filter membrane 113, the blood flows to the colloidal gold test strip 102 through the first flow guide plate 114, when feces are used as a sample, the switching slider 107 is slid to the left side, and the feces are put into the sample processing groove 103 on the right side, after the feces are filtered by the filter screen 112, the feces flow into the colloidal gold test strip 102 through the second flow guide plate 115, and the specific detection principle is that the blood is filtered by the filter membrane 113 to filter red blood cells, the plasma enters the colloidal gold labeling area, the target antigen in the plasma is combined with the colloidal gold labeled antibody to form a complex, the complex is chromatographed to the T line, is captured by the fixed antibody, and is colored (such as a red strip), the excess complex continues to migrate to the C line to be colored, the quality control is completed, if the sample is feces, the sample is intercepted by the filter screen 112 to filter out fiber materials, the filtrate enters the colloidal gold labeling area, the target antigen (such as rotavirus antigen) is combined with the colloidal gold labeled monoclonal antibody, the complex is chromatographed to the T line, is captured by the polyclonal antibody, and is colored, the remaining complex migrates to the C line to verify the effectiveness, so as to complete the switching detection of the blood and feces double-sample mode.

[0027] The above only discloses one or more preferred embodiments of the application, and cannot limit the scope of the application, and those skilled in the art can understand that all or part of the above-mentioned embodiments can be implemented, and equivalent changes made according to the claims of the application still belong to the scope of the application.

Claims

1. A colloidal gold dual-sample reagent kit with blood / feces dual-mode switching function, comprising a main shell and a colloidal gold test strip, wherein a sample processing slot and a detection display slot are respectively provided on both sides of the main shell, and the colloidal gold test strip is fixedly installed inside the main shell, characterized in that, It also includes a switching device; The switching device includes a switching plate, a connecting block, a switching slider, a partition plate, a guide assembly, a filter assembly, and a flow guiding assembly. The switching plate is slidably installed inside the main body shell via the guide assembly. The connecting block is fixedly installed on the switching plate. A through groove is provided on one side of the main body shell. The connecting block passes through the through groove and extends to the outside of the main body shell. The switching slider is fixedly installed on the connecting block. The partition plate is fixedly installed on the main body shell and located inside the sample processing tank. The filter assembly is disposed inside the sample processing tank. The flow guiding assembly is disposed on the partition plate.

2. The colloidal gold dual-sample reagent kit with blood / feces dual-mode switching function as described in claim 1, characterized in that, The guide assembly includes a fixing block and a guide protrusion. The fixing block is fixedly installed inside the main body shell and has a sliding groove. The guide protrusion is fixedly installed on the switching plate and slides in cooperation with the sliding groove.

3. The colloidal gold dual-sample reagent kit with blood / feces dual-mode switching function as described in claim 1, characterized in that, The filtration assembly includes a filter screen and a filter membrane. Both the filter membrane and the filter screen are fixedly installed on the main body shell and are located inside the sample processing tank. The filter membrane and the filter screen are respectively disposed on both sides of the partition plate.

4. The colloidal gold dual-sample reagent kit with blood / feces dual-mode switching function as described in claim 1, characterized in that, The flow guiding assembly includes a first flow guiding plate and a second flow guiding plate. The first flow guiding plate and the second flow guiding plate are respectively fixedly installed on both sides of the partition plate and are in contact with the switching plate.

5. The colloidal gold dual-sample reagent kit with blood / feces dual-mode switching function as described in claim 1, characterized in that, An observation window is also provided on one side of the main body shell, and the observation window is located in the detection display slot.

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