Stem cell induction culture equipment

By fixing the culture flask with clamps and springs, and combining it with a detachable filter and humidification device, the problem of easy displacement of the culture flask is solved, thus achieving the stability of the culture flask and the experimental environment, and ensuring the smooth progress of stem cell induction culture.

CN224077428UActive Publication Date: 2026-04-03BEIJING JINGZHUN BIOTECHNOLOGY CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-04-24
Publication Date
2026-04-03

AI Technical Summary

Technical Problem

In existing stem cell induction culture equipment, culture flasks placed flat on the partition are prone to displacement or tipping, resulting in uneven distribution of culture medium, which affects the experimental process and the normal use of the equipment.

Method used

The culture flasks are secured using a clamp and spring structure. The clamps and rubber pads work together, utilizing the elasticity of the springs and the friction of the rubber pads to fix the culture flasks. Combined with a detachable filter design, quick assembly and disassembly and air filtration are achieved. A humidification tray is added to maintain a suitable humidity environment.

Benefits of technology

It improves the stability of culture flasks, prevents shaking and tipping, ensures uniform distribution of culture medium, reduces the risk of contamination, shortens equipment exposure time, maintains suitable humidity conditions, and ensures the smooth progress of experiments.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of culture equipment, and discloses stem cell induction culture equipment which comprises a culture box body, a door plate is arranged on the side wall of the culture box body, a fixing frame is fixedly connected to the interior of the culture box body, a partition plate is slidably connected to the interior of the fixing frame, a filter is arranged in the culture box body, and the partition plate and the filter are arranged in the culture box body. A fixing assembly is arranged on the upper surface of the partition plate, and a mounting assembly is arranged in the incubator body; the fixing assembly comprises a first clamping plate and a second clamping plate, the lower surface of the first clamping plate is fixedly connected to the upper surface of the partition plate, and the lower surface of the second clamping plate is fixedly connected with a connecting block. According to the utility model, by holding the handle and pulling the second clamping plate, the distance between the first clamping plate and the second clamping plate is increased, a culture bottle is placed between the first clamping plate and the second clamping plate, the handle is loosened, the first spring recovers deformation, and then the second clamping plate is driven to approach the first clamping plate, so that the rubber pad is attached to the side wall of the culture bottle to achieve a fixing effect; through the structure, the stability of the culture bottle is improved.
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Description

Technical Field

[0001] This utility model relates to the field of culture equipment technology, and in particular to a stem cell induction culture device. Background Technology

[0002] In the life sciences, stem cells, with their unique differentiation potential, have become a core element in regenerative medicine, disease treatment research, and other fields. Whether used to repair damaged organs and tissues or to explore new therapies for intractable diseases, high-quality stem cell culture is a crucial step. This drives researchers to continuously pursue more advanced and stable stem cell induction and culture equipment to meet the growing research and application demands and ensure the precision and reliability of the stem cell culture process.

[0003] Currently available stem cell induction culture equipment is primarily structured around a sealed culture chamber. This chamber features a robust system for temperature, humidity, and gas environment control. Through sophisticated sensors and an intelligent control system, it maintains the stability of various parameters within the chamber. When placing the culture flask, it is simply laid flat on a partition. The underlying technology is based on gravity and simple planar support; that is, the downward vertical force of the culture flask's own weight is balanced by the upward support provided by the partition, thus maintaining relative stability of the culture flask in a static state.

[0004] In existing stem cell induction culture equipment, when operators frequently operate the equipment and move experimental materials, they inevitably bump into the table where the incubator is placed. Under the influence of these external interference factors, the culture bottles that are simply placed flat on the partition are prone to displacement due to the lack of effective fastening measures, resulting in uneven distribution of culture medium, which greatly affects the experimental process and normal use of the equipment. Therefore, a stem cell induction culture device is proposed to solve the above problems. Utility Model Content

[0005] To overcome the above shortcomings, this utility model provides a stem cell induction culture device, which aims to improve the problem in the prior art where culture flasks placed flat on the partition are prone to displacement or even tipping over, resulting in uneven distribution of culture medium and greatly affecting the experimental process and normal use of the equipment.

[0006] To achieve the above objectives, the present invention adopts the following technical solution:

[0007] A stem cell induction culture device includes a culture chamber body, a door panel provided on the side wall of the culture chamber body, a fixing frame fixedly connected inside the culture chamber body, a partition slidably connected inside the fixing frame, a filter provided inside the culture chamber body, a fixing component provided on the upper surface of the partition, and an installation component provided inside the culture chamber body.

[0008] The fixing assembly includes a first clamp and a second clamp. The lower surface of the first clamp is fixedly connected to the upper surface of the partition. A connecting block is fixedly connected to the lower surface of the second clamp. The side wall of the connecting block is slidably connected to the inside of the partition. A slider is fixedly connected to the lower surface of the connecting block. The side wall of the slider is slidably connected to the inside of the partition. A spring is fixedly connected to the side wall of the slider. One end of the spring is fixedly connected to the inside of the partition. Rubber pads are fixedly connected to the side walls of both the first and second clamps. A handle is fixedly connected to the upper surface of the second clamp.

[0009] As a further description of the above technical solution:

[0010] The mounting assembly includes a mounting block, which is fixedly connected inside the incubator body, and the sidewall of the mounting block is slidably connected inside the filter.

[0011] As a further description of the above technical solution:

[0012] The mounting block is fixedly connected to a mounting base, and a spring is installed inside the mounting block.

[0013] As a further description of the above technical solution:

[0014] One end of the second spring is fixedly connected to the side wall of the mounting base, and the other end of the second spring is fixedly connected to a limit block.

[0015] As a further description of the above technical solution:

[0016] The side wall of the limiting block is slidably connected inside the mounting block, and a locking block is fixedly connected to the side wall of the limiting block.

[0017] As a further description of the above technical solution:

[0018] The filter has a slot inside, and the side wall of the card block is slidably connected inside the slot.

[0019] As a further description of the above technical solution:

[0020] An inner door is rotatably connected to the inside of the door panel, and a heating wire is installed inside the inner door to prevent condensation.

[0021] As a further description of the above technical solution:

[0022] The incubator body is equipped with a humidification tray to increase the humidity inside the incubator body.

[0023] This utility model has the following beneficial effects:

[0024] 1. In this utility model, by holding the handle and pulling the second clamp, the connecting block and the slider slide inside the partition. At this time, the distance between the first clamp and the second clamp increases. The culture bottle is placed between the two. When the handle is released, the first spring returns to its original deformation, pushing the slider and the connecting block, which in turn drives the second clamp closer to the first clamp, so that the rubber pad fits against the side wall of the culture bottle, achieving a fixing effect. This solves the problem that in some stem cell induction culture equipment, the culture bottle is simply placed flat on the partition, which is easy to shift or even tip over, resulting in uneven distribution of culture medium, which greatly affects the experimental process and normal use of the equipment. The above structure improves the stability of the culture bottle.

[0025] 2. In this utility model, by pushing the filter downwards, the locking block is squeezed and slides into the mounting block, squeezing the spring, thereby causing the locking block to disengage from the slot and release the fixing effect. At this time, the filter can be removed from the mounting block and replaced, achieving a quick disassembly and assembly effect, shortening the exposure time of the incubator, and reducing the risk of contamination. Attached Figure Description

[0026] Figure 1 This is a three-dimensional schematic diagram of a stem cell induction culture device proposed in this utility model;

[0027] Figure 2 This is a schematic diagram of the internal structure of the culture chamber of a stem cell induction culture device proposed in this utility model;

[0028] Figure 3 This is a schematic diagram of the structure of the partition of a stem cell induction culture device proposed in this utility model;

[0029] Figure 4 This is a schematic diagram of the structure of the mounting block of a stem cell induction culture device proposed in this utility model;

[0030] Figure 5 for Figure 3 Enlarged view of point A in the middle.

[0031] Legend:

[0032] 1. Incubator body; 2. Door panel; 3. Inner door; 4. Fixing frame; 5. Partition; 6. Filter; 7. Humidification tray; 8. Clamping plate one; 9. Rubber pad; 10. Clamping plate two; 11. Connecting block; 12. Sliding block; 13. Spring one; 14. Handle; 15. Mounting block; 16. Slot; 17. Mounting base; 18. Spring two; 19. Limiting block; 20. Locking block. Detailed Implementation

[0033] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0034] Reference Figure 1 , Figure 2 , Figure 3 and Figure 5This utility model provides an embodiment of a stem cell induction culture device, comprising a culture chamber body 1, a door panel 2 on the side wall of the culture chamber body 1 for easy access by the experimenter, a fixed frame 4 inside the culture chamber body 1 for supporting and positioning partitions 5, and a sliding partition 5 inside the fixed frame 4 for easy placement and removal of culture flasks, and a filter 6 inside the culture chamber body 1 for filtering the air entering the culture chamber body 1, removing impurities, microorganisms, etc., and reducing the risk of contamination. To improve the success rate of cultivation, a fixing component is provided on the upper surface of the partition 5, and an installation component is provided inside the incubator body 1. The fixing component includes a first clamp 8 and a second clamp 10. The lower surface of the first clamp 8 is fixedly connected to the upper surface of the partition 5, which serves to fix the position on one side. A connecting block 11 is fixedly connected to the lower surface of the second clamp 10. The connecting block 11 is used to connect the second clamp 10 and the slider 12. The side wall of the connecting block 11 is slidably connected inside the partition 5, so that the second clamp 10 can slide under the constraint of the partition 5. The slider 12 is fixedly connected to the lower surface of the connecting block 11. The slider 12 slides inside the partition 5, driving the connecting block 11 and the second clamp 10 to move. The slider 12 is moved to adjust the distance between clamp 11 and clamp 2 10. A spring 13 is fixedly connected to the side wall of the slider 12. One end of the spring 13 is fixedly connected to the inside of the partition 5. When the spring 13 is not subjected to external force, it pushes the slider 12, the connecting block 11, and the clamp 2 10 closer to clamp 11, thereby clamping and fixing the culture flask. Rubber pads 9 are fixedly connected to the side walls of clamp 11 and clamp 2 10. The rubber pads 9 have a certain elasticity and friction to protect the side walls of the culture flask from being scratched. A handle 14 is fixedly connected to the upper surface of clamp 2 10, so that the experimenter can pull clamp 2 10 by holding the handle 14, so that the connecting block 11... The slider 12 slides inside the partition 5 to facilitate the placement of culture flasks. The door panel 2 is rotatably connected to the inner door 3, which is equipped with a heating wire. The heating wire can increase the temperature of the inner door 3 and prevent condensation from forming on the inside of the door panel 2 when the air with a lower temperature inside the incubator body 1 comes into contact with the door panel 2. This avoids the condensation from affecting the culture environment and experiments. The incubator body 1 is equipped with a humidification tray 7, which is used to increase the humidity inside the incubator body 1. Through the natural evaporation of water, the humidity inside the incubator body 1 reaches the appropriate range required for stem cell induction culture, providing suitable humidity conditions for the growth and differentiation of stem cells.

[0035] Reference Figure 2 and Figure 4The installation assembly includes a mounting block 15, which is fixedly connected inside the incubator body 1. The side wall of the mounting block 15 is slidably connected inside the filter 6. A mounting base 17 is fixedly connected inside the mounting block 15, serving to fix one end of a second spring 18 and providing a support point for the second spring 18, ensuring that the second spring 18 can function normally within the mounting block 15. A second spring 18 is installed inside the mounting block 15, with one end fixedly connected to the side wall of the mounting base 17 and the other end fixedly connected to a limit block 19. Having elastic potential energy, under natural conditions, it will give the limiting block 19 an outward pushing force. The side wall of the limiting block 19 is slidably connected to the inside of the mounting block 15. Under the action of the second spring 18, the limiting block 19 can slide along a specific track inside the mounting block 15. Its sliding range is limited by the internal structure of the mounting block 15. The side wall of the limiting block 19 is fixedly connected to the locking block 20. The filter 6 has a locking groove 16 inside. The side wall of the locking block 20 is slidably connected to the inside of the locking groove 16. When the filter 6 is installed, the locking block 20 will first contact the locking groove 16 inside the filter 6.

[0036] Working principle: When it is necessary to fix the culture flask, the operator holds handle 14 and applies force to pull clamp 2 10. During this process, the connecting block 11 and slider 12 connected to clamp 2 10 slide synchronously inside the partition 5, causing spring 13 to contract, which increases the distance between clamp 1 8 and clamp 2 10. At this time, the culture flask is placed between them. Then, the handle 14 is released, and spring 13 returns to its original deformation due to the removal of external force. The resulting elastic force pushes slider 12 and connecting block 11 to slide in the opposite direction, thereby driving clamp 2 10 closer to clamp 1 8. Since rubber pads 9 are fixed to the side walls of clamp 1 8 and clamp 2 10, the rubber pads 9 have good... The flexibility and friction allow the rubber pad 9 to adhere to the side wall of the culture flask as the clamp 2 10 approaches the clamp 1 8. The elasticity of the spring 13 and the friction between the rubber pad 9 and the culture flask effectively fix the flask, preventing shaking and tipping caused by external factors such as vibration and collision during culture, thus ensuring the stability of the stem cell culture environment. When installing the filter 6, it is aligned with the mounting block 15 and inserted. As the insertion depth increases, the locking block 20 is squeezed by the filter 6, pushing the limiting block 19 towards the mounting base 17, compressing the spring 2 18. When the locking block 20 slides to the slot 16, the spring 2 18 returns to its original shape, pushing the limiting block 19 towards the mounting base 17. Block 19 and locking block 20 are inserted into the slot 16, completing the secure installation of filter 6. During operation, outside air passes through the multi-layer filtration structure of filter 6, effectively filtering out dust particles, microorganisms, and other impurities, creating a clean air environment for stem cell induction culture. When filter 6 needs to be replaced, push filter 6 downwards, causing locking block 20 to slide into the mounting block 15 and compress spring 18, thereby disengaging locking block 20 from the slot 16, releasing the fixing effect, and filter 6 can then be removed from mounting block 15 for replacement. During equipment operation, the moisture in the humidification tray 7 continuously absorbs surrounding heat, converting it into water vapor which is released into the culture medium. The internal space of the chamber body 1, by controlling the amount of water in the humidification tray 7 and the rate of heat exchange with the surrounding environment, can maintain the humidity inside the incubator at a stable range suitable for stem cell growth and induced differentiation, avoiding problems such as metabolic disorders and morphological changes caused by cell dehydration, and ensuring the smooth progress of stem cell induction culture experiments. The heating wire installed inside the inner door 3 is powered on during equipment operation to increase the temperature of the inner door 3 to cope with the high humidity environment inside the incubator body 1, and prevent hot and humid air from cooling on the surface of the inner door 3, thereby avoiding the formation of condensation. This not only avoids the risk of water droplets contaminating the culture, but also helps to maintain a uniform and stable temperature field inside the chamber.

[0037] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A stem cell induction culture device, comprising a culture chamber body (1), characterized in that: The incubator body (1) has a door panel (2) on its side wall. The incubator body (1) has a fixed frame (4) fixedly connected inside. The fixed frame (4) has a partition (5) slidably connected inside. The incubator body (1) has a filter (6) inside. The upper surface of the partition (5) has a fixing component. The incubator body (1) has an installation component inside. The fixing assembly includes a clamping plate one (8) and a clamping plate two (10). The lower surface of the clamping plate one (8) is fixedly connected to the upper surface of the partition plate (5). A connecting block (11) is fixedly connected to the lower surface of the clamping plate two (10). The side wall of the connecting block (11) is slidably connected to the inside of the partition plate (5). A slider (12) is fixedly connected to the lower surface of the connecting block (11). The side wall of the slider (12) is slidably connected to the inside of the partition plate (5). A spring one (13) is fixedly connected to the side wall of the slider (12). One end of the spring one (13) is fixedly connected to the inside of the partition plate (5). Rubber pads (9) are fixedly connected to the side walls of both the clamping plate one (8) and the clamping plate two (10). A handle (14) is fixedly connected to the upper surface of the clamping plate two (10).

2. The stem cell induction culture device according to claim 1, characterized in that: The installation assembly includes an installation block (15), which is fixedly connected inside the incubator body (1), and the side wall of the installation block (15) is slidably connected inside the filter (6).

3. The stem cell induction culture device according to claim 2, characterized in that: The mounting block (15) is fixedly connected to a mounting base (17), and a spring (18) is provided inside the mounting block (15).

4. The stem cell induction culture device according to claim 3, characterized in that: One end of the second spring (18) is fixedly connected to the side wall of the mounting base (17), and the other end of the second spring (18) is fixedly connected to the limit block (19).

5. The stem cell induction culture device according to claim 4, characterized in that: The side wall of the limiting block (19) is slidably connected inside the mounting block (15), and a locking block (20) is fixedly connected to the side wall of the limiting block (19).

6. The stem cell induction culture device according to claim 5, characterized in that: The filter (6) has a slot (16) inside, and the side wall of the card block (20) is slidably connected to the slot (16).

7. The stem cell induction culture device according to claim 1, characterized in that: The door panel (2) is rotatably connected to an inner door (3), and a heating wire is installed inside the inner door (3) to prevent condensation.

8. The stem cell induction culture device according to claim 1, characterized in that: The incubator body (1) is equipped with a humidification tray (7) to increase the humidity inside the incubator body (1).