Slide preparation equipment for thin-layer liquid-based cells

Abstract

The utility model belongs to the technical field of medical detection equipment, and particularly relates to slide preparation equipment for thin-layer liquid-based cells, which comprises a machine body, the machine body comprises an upper layer, a middle layer and a lower layer, a loading area and a storage area are arranged at two ends of the lower layer of the machine body, and a glass slide loading frame is placed in the loading area and the storage area; conveying frames are installed on the two sides of the machine body and located on the middle layer of the machine body, chain wheels are installed at the two ends of each conveying frame, the two chain wheels are connected through a chain, and a glass slide carrying frame located on the middle layer of the machine body conveys through chain transmission. A capping mechanism and a dripping mechanism are installed on the upper layer of the machine body, the capping mechanism comprises a first electric guide rail, a slidable adsorption frame is installed below the first electric guide rail, and the dripping mechanism comprises a second electric guide rail. The glass slide loading frame can be automatically and continuously conveyed, glass slides can be sealed in batches, the glass slide sealing efficiency is higher, and the glass slide sealing device is suitable for being used in the scene of large-batch slide preparation.

Description

Technical Field

[0001] This utility model belongs to the field of medical testing equipment technology, specifically relating to a thin-layer liquid-based cell preparation device. Background Technology

[0002] Thin-layer liquid-based cytology preparation is a key technology for pathological testing, mainly used for cervical cancer screening (such as TCT testing) and cytological examination of respiratory or body fluid samples. The complete preparation process can be summarized as sample collection, processing, preparation, staining, and mounting. As the final step in the preparation process, mounting the slide can isolate it from air, prevent the stained cells from fading, and isolate it from external contamination. At the same time, it can prevent cells from falling off, which can greatly extend the archiving time of the slide. In addition, the fixation and mounting with resin can also maintain the clarity of cell morphology, making it easier to observe.

[0003] However, current slide preparation equipment often uses mechanical structures to transport and seal single slides, resulting in low sealing efficiency. Since unsealed cells have a limited shelf life, this method is only suitable for small-scale slide preparation scenarios and cannot meet the needs of scenarios requiring large-scale slide preparation. Utility Model Content

[0004] The purpose of this invention is to provide a thin-layer liquid-based cell preparation device that can automatically and continuously transport a slide loading rack and seal slides in batches, with higher sealing efficiency, and is suitable for use in scenarios involving large-volume slide preparation.

[0005] The specific technical solution adopted by this utility model is as follows:

[0006] A thin-layer liquid-based cell preparation device includes a body, which includes an upper layer, a middle layer and a lower layer. The lower layer of the body has a loading area and a storage area at both ends, and a slide carrier is placed in the loading area and the storage area.

[0007] The machine body is equipped with conveyor frames on both sides, the conveyor frames are located in the middle layer of the machine body, the two ends of the conveyor frames are equipped with sprockets, the two sprockets are connected by a chain, and the glass slide carrier located in the middle layer of the machine body is conveyed by chain drive.

[0008] The upper layer of the device is equipped with a capping mechanism and an infusion mechanism. The capping mechanism includes a first electric guide rail, and a slidable suction holder is installed below the first electric guide rail. The infusion mechanism includes a second electric guide rail, and a slidable infusion holder is installed below the second electric guide rail. A coverslip holder is provided at one end of the upper layer of the device.

[0009] Furthermore, a first electric push rod is installed on one side of the loading area and storage area, and a lifting frame is fixed to the output end of the first electric push rod, with the glass slide carrier placed above the lifting frame.

[0010] Furthermore, a motor is fixed in the middle of the machine body, the output end of the motor is fixed to one of the sprockets, a connecting rod is fixed between the two sprockets located at one end of the two conveyor frames, and several fixing parts are evenly fixed on one side of the chain, with a second electric push rod installed at one end of each fixing part.

[0011] Furthermore, the sealing mechanism also includes an air pump, which is fixed to the top of the machine body. An air pipe is fixed to the bottom of the air pump, and the bottom end of the air pipe is connected to the adsorption frame. A third electric push rod is slidably connected to the bottom of the first electric guide rail, and the output end of the third electric push rod is fixed to the top of the adsorption frame.

[0012] Furthermore, the drip mechanism also includes a resin storage tank, which is fixed to the top of the machine body. A delivery pipe is fixed to the bottom of the resin storage tank, and the bottom end of the delivery pipe is connected to the drip holder. A fixing frame is fixed to the output end of the second electric guide rail, and the bottom of the fixing frame is fixed to the top of the drip holder.

[0013] Furthermore, the lifting frame is L-shaped.

[0014] Furthermore, the slide holder has openings on both sides that match the second electric push rod.

[0015] Furthermore, the resin storage tank integrates a delivery pump.

[0016] The technical effects achieved by this utility model are as follows:

[0017] This invention, through a motor-driven chain combined with a fixing component and a second electric push rod, enables the conveying of slide carriers at the same level. Simultaneously, by combining the first electric push rod with a lifting frame to control the lifting and lowering of the slide carriers, the device possesses the functions of automatic lifting, alignment, and continuous conveying of slide carriers. Furthermore, in conjunction with a capping mechanism and an infusion mechanism, the device enables continuous slide sealing, resulting in higher sealing efficiency and suitability for applications requiring large-volume slide production. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the structure of this utility model;

[0019] Figure 2 This is a partial cross-sectional structural diagram of the present invention;

[0020] Figure 3This is a schematic diagram of the chain conveyor structure of this utility model;

[0021] Figure 4 This is a schematic diagram of the sealing mechanism and the dripping mechanism of this utility model.

[0022] The attached diagram lists the components represented by each number as follows:

[0023] 1. Body; 2. Conveyor frame; 3. Covering mechanism; 4. Drip mechanism; 11. Loading area; 12. Storage area; 13. First electric push rod; 14. Lifting frame; 15. Slide holder; 16. Cover slide holder; 21. Sprocket; 22. Chain; 23. Connecting rod; 24. Motor; 25. Fixture; 26. Second electric push rod; 31. Air pump; 32. First electric guide rail; 33. Third electric push rod; 34. Adsorption rack; 35. Air pipe; 41. Resin storage box; 42. Second electric guide rail; 43. Fixing frame; 44. Drip rack; 45. Conveyor pipe. Detailed Implementation

[0024] To make the objectives and advantages of this utility model clearer, the following detailed description is provided in conjunction with embodiments. It should be understood that the following text is merely used to describe one or more specific embodiments of this utility model and does not strictly limit the scope of protection specifically claimed by this utility model.

[0025] like Figures 1 to 4 As shown, a thin-layer liquid-based cell preparation device includes a body 1, which includes an upper layer, a middle layer and a lower layer. The lower layer of the body 1 has a loading area 11 and a storage area 12 at both ends, and a slide carrier 15 is placed in the loading area 11 and the storage area 12.

[0026] The machine body 1 is equipped with conveyor frames 2 on both sides. The conveyor frames 2 are located in the middle layer of the machine body 1. The two ends of the conveyor frames 2 are equipped with sprockets 21. The two sprockets 21 are connected by a chain 22. The glass slide carrier 15 located in the middle layer of the machine body 1 is driven and transported by the chain 22.

[0027] The upper part of the body 1 is equipped with a capping mechanism 3 and an infusion mechanism 4. The capping mechanism 3 includes a first electric guide rail 32, and a slidable suction holder 34 is installed below the first electric guide rail 32. The infusion mechanism 4 includes a second electric guide rail 42, and a slidable infusion holder 44 is installed below the second electric guide rail 42. A cover glass slide carrier 16 is provided at one end of the upper part of the body 1.

[0028] As described above, during use, the stained slides are placed on the slide holder 15, and the slide holders 15 are stacked and placed inside the loading area 11 for pre-loading. During the sealing process, the slide holder 15 is transported by the rotating chain 22, moving it to the sealing area. The drip holder 44 is moved above the slide holder 15 by the second electric guide rail 42, and resin is squeezed onto the surface of the slide. The suction holder 34 is moved above the coverslip holder 16 by the first electric guide rail 32, and the coverslip is suctioned by the suction holder 34. After sealing, the slide holder 15 is moved to the storage area 12 by rotating the chain 22 again to complete the sealing.

[0029] Please refer to it again. Figure 2 As shown, a first electric push rod 13 is installed on one side of the loading area 11 and the storage area 12. A lifting frame 14 is fixed to the output end of the first electric push rod 13. A glass slide carrier 15 is placed above the lifting frame 14. The lifting frame 14 is L-shaped.

[0030] As described above, after the pre-loaded slide holder 15 is completed, the lifting frame 14 is raised by the first electric push rod 13, so that the uppermost slide holder 15 is at the same level as the sealing area, which facilitates the movement of the slide holder 15 to the sealing area. After one slide holder 15 enters the sealing area, it drives the next slide holder 15 to the same height. Similarly, the first electric push rod 13 located in the storage area 12 is used to drive the placed slide holder 15 below the sealing area, which facilitates the movement of the next slide holder 15 to the storage area 12.

[0031] Please refer to it again. Figure 3 As shown, a motor 24 is fixed in the middle of the machine body 1. The output end of the motor 24 is fixed to one of the sprockets 21. A connecting rod 23 is fixed between the two sprockets 21 located at one end of the two conveyor frames 2. Several fixing parts 25 are evenly fixed on one side of the chain 22. A second electric push rod 26 is installed at one end of the fixing part 25. Openings matching the second electric push rod 26 are provided on both sides of the slide carrier 15.

[0032] In the above-mentioned process, when the slide carrier 15 is moved, the motor 24 drives the sprocket 21 to rotate, which in turn drives the chain 22 to rotate. Through the transmission of the connecting rod 23, the chains 22 on both sides rotate together, and at the same time, the fixed fastener 25 on one side moves together. When the second electric push rod 26 is aligned with the openings on both sides of the slide carrier 15, the output end of the second electric push rod 26 can be inserted into the opening to drive the slide carrier 15 to move together when the chain 22 rotates.

[0033] It should be noted that the other end of the fixing member 25 is equipped with an electrical contact rod, and an electrical contact piece is installed inside the conveying frame 2 at the same height as the sealing area. The two ends of the electrical contact piece are located above the loading area 11 and the storage area 12, respectively. When the second electric push rod 26 is at the same height as the sealing area, the electrical contact rod and the electrical contact piece are connected, so that the second electric push rod 26 is powered on. When the second electric push rod 26 moves to the height below the sealing area, the electrical contact rod and the electrical contact piece are disengaged, and the second electric push rod 26 is de-energized.

[0034] Please refer to the following: Figure 2 and Figure 4 As shown, the drip mechanism 4 also includes a resin storage tank 41, which integrates a delivery pump. The resin storage tank 41 is fixed to the top of the body 1, and a delivery pipe 45 is fixed to the bottom of the resin storage tank 41. The bottom end of the delivery pipe 45 is connected to the drip holder 44. A fixing frame 43 is fixed to the output end of the second electric guide rail 42, and the bottom of the fixing frame 43 is fixed to the top of the drip holder 44.

[0035] In the above process, the resin storage box 41 is moved together with the fixing frame 43 and the drip rack 44 to the slide mounting frame 15 in the sealing area. The resin is then transported from the resin storage box 41 to the drip rack 44 via the delivery pipe 45 and dripped onto the slide. The mechanical control of the resin dripping can achieve a more uniform dripping than manual dripping.

[0036] Please refer to the following: Figure 2 and Figure 4 As shown, the sealing mechanism 3 also includes an air pump 31, which is fixed to the top of the body 1. An air pipe 35 is fixed to the bottom of the air pump 31. The bottom end of the air pipe 35 is connected to the adsorption frame 34. A third electric push rod 33 is slidably connected to the bottom of the first electric guide rail 32. The output end of the third electric push rod 33 is fixed to the top of the adsorption frame 34.

[0037] As described above, during the cover plate preparation, the air pump 31 enables the bottom of the suction holder 34 to have suction force, controls the suction holder 34 to move above the cover plate carrier 16, and drives the suction holder 34 to descend via the third electric push rod 33, so that the cover plate is adsorbed below the suction holder 34. Then, the suction holder 34 is controlled to move above the slide carrier 15 in the sealing area, and the suction holder 34 is controlled to descend via the third electric push rod 33, so that the cover plate is pressed onto the slide, completing the sealing process.

[0038] It should be noted that both the first electric guide rail 32 and the second electric guide rail 42 adopt existing mature electric slide rail technology, and the specific principles will not be elaborated here.

[0039] The working principle of this utility model is as follows: The slide carrier 15 is placed in the loading area 11. The first electric push rod 13 drives the lifting frame 14 to raise the slide carrier 15 until it is flush with the sealing area. Then, the motor 24 drives the chain 22 to rotate, which in turn moves the fixing member 25 and the second electric push rod 26. Simultaneously, the output end of the second electric push rod 26 is inserted into the opening of the slide carrier 15, moving the slide carrier 15 to the sealing area. The second electric guide rail 42 controls the drip holder 44 to move above the slide, and the resin is delivered through the resin storage box 41. The resin is extruded through the delivery tube 45 and placed under the drip holder 44, evenly covering the surface of the slide. Then, the drip holder 44 is reset, and the air pump 31 is activated to adsorb the coverslip on the coverslip holder 16 under the adsorption holder 34. The air pump 31 moves the adsorption holder 34 above the resin-covered slide, and the third electric push rod 33 lowers the adsorption holder 34 to complete the sealing. After that, the adsorption holder 34 is reset, and the chain 22 is rotated to move the slide holder 15 containing the sealed slides to the storage area 12 for temporary storage, and the unsealed slides are moved to the sealing area.

[0040] The above description is merely a preferred embodiment of this utility model. It should be noted that those skilled in the art can make various improvements and modifications without departing from the principle of this utility model, and these improvements and modifications should also be considered within the scope of protection of this utility model. Structures, devices, and operating methods not specifically described or explained in this utility model, unless otherwise specified or limited, shall be implemented using conventional methods in the field.

Claims

1. A thin-layer liquid-based cell preparation device, characterized in that: Includes a body (1), which includes an upper layer, a middle layer and a lower layer. The lower layer of the body (1) is provided with a loading area (11) and a storage area (12) at both ends. A glass slide carrier (15) is placed in the loading area (11) and the storage area (12). The machine body (1) is equipped with conveyor frames (2) on both sides. The conveyor frames (2) are located in the middle layer of the machine body (1). The two ends of the conveyor frames (2) are equipped with sprockets (21). The two sprockets (21) are connected by a chain (22). The slide carrier (15) located in the middle layer of the machine body (1) is driven and transported by the chain (22). The upper layer of the body (1) is equipped with a capping mechanism (3) and a dripping mechanism (4). The capping mechanism (3) includes a first electric guide rail (32), and a slidable suction holder (34) is installed below the first electric guide rail (32). The dripping mechanism (4) includes a second electric guide rail (42), and a slidable drip holder (44) is installed below the second electric guide rail (42). A cover glass slide holder (16) is provided at one end of the upper layer of the body (1).

2. The thin-layer liquid-based cell preparation device according to claim 1, characterized in that: A first electric push rod (13) is installed on one side of the loading area (11) and the storage area (12), and a lifting frame (14) is fixed to the output end of the first electric push rod (13). The slide carrier (15) is placed above the lifting frame (14).

3. The thin-layer liquid-based cell preparation device according to claim 1, characterized in that: A motor (24) is fixed in the middle of the body (1). The output end of the motor (24) is fixed to one of the sprockets (21). A connecting rod (23) is fixed between the two sprockets (21) located at one end of the two conveyor frames (2). Several fixing parts (25) are evenly fixed on one side of the chain (22). A second electric push rod (26) is installed at one end of the fixing part (25).

4. The thin-layer liquid-based cell preparation device according to claim 1, characterized in that: The sealing mechanism (3) also includes an air pump (31), which is fixed on the top of the body (1). An air pipe (35) is fixed at the bottom of the air pump (31). The bottom end of the air pipe (35) is connected to the adsorption rack (34). A third electric push rod (33) is slidably connected to the bottom of the first electric guide rail (32). The output end of the third electric push rod (33) is fixed on the top of the adsorption rack (34).

5. The thin-layer liquid-based cell preparation device according to claim 1, characterized in that: The drip mechanism (4) also includes a resin storage box (41), which is fixed to the top of the body (1). A delivery pipe (45) is fixed to the bottom of the resin storage box (41). The bottom end of the delivery pipe (45) is connected to the drip holder (44). A fixing frame (43) is fixed to the output end of the second electric guide rail (42). The bottom of the fixing frame (43) is fixed to the top of the drip holder (44).

6. The thin-layer liquid-based cell preparation device according to claim 2, characterized in that: The lifting frame (14) is L-shaped.

7. The thin-layer liquid-based cell preparation device according to claim 3, characterized in that: The slide holder (15) has openings on both sides that match the second electric push rod (26).

8. The thin-layer liquid-based cell preparation device according to claim 5, characterized in that: The resin storage tank (41) has an integrated transfer pump inside.

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