Impurity detection device for esculentin raw material medicine

By designing a cleaning side plate and chuck structure in the eribulin raw material impurity detection device, the problem of detection deviation caused by impurity residue adhesion was solved, ensuring the accuracy and efficiency of the detection results.

CN224095833UActive Publication Date: 2026-04-07HSING PHARMACEUTICALS CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-04-28
Publication Date
2026-04-07

AI Technical Summary

Technical Problem

In existing impurity detection devices for eribulin raw materials, impurity residues adhere to the inner wall, forming hard lumps that cause deviations in detection results, affecting detection efficiency and quality.

Method used

A device comprising a mounting base, a detection cylinder, and a cleaning component is designed. The cleaning component consists of two cleaning side plates, which are driven to rotate by a drive component. The side plates are provided with a discharge port and a shredding head for cleaning residue from the inner wall of the detection tank. The cleaning component is detachably connected to the bottom of the detection tank via a chuck for easy disassembly.

Benefits of technology

This allows for the orderly cleaning of the inner wall of the testing tank after testing, preventing residue from affecting subsequent testing results and improving the accuracy and efficiency of testing.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the related technical field of impurity detection of raw material medicines, and discloses a device for detecting impurities of an esculentin raw material medicine, which comprises a mounting base and a detection cylinder arranged on the mounting base, a detection groove for pouring the raw material medicine is arranged in the detection cylinder, the top of the detection groove is open, and the top of the detection groove is open. And a cleaning piece is arranged in the detection groove. Through the arrangement of the mounting base, the detection cylinder body and the detection groove, the detection process can be carried out in a stable environment, and through the rotary arrangement of the cleaning side plate in the cleaning piece, the purpose of orderly scraping and cleaning the inner wall of the detection groove after the detection is finished can be achieved; the influence of residual impurity solids on subsequent liquid medicine detection is avoided, so that the whole detection result is relatively accurate, and the aim of conveniently disassembling and assembling the whole cleaning piece from and in the cleaning groove is achieved through the arrangement of a chuck.
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Description

TECHNICAL FIELD

[0001] The utility model relates to the related technical field of raw material medicine impurity detection, especially a eribulin raw material medicine impurity detection device. BACKGROUND

[0002] Eribulin raw material medicine impurity detection is the process of post-treatment of the liquid medicine, which can avoid the influence of excessive impurities on the effect of eribulin raw material medicine.

[0003] In the detection process of most existing eribulin raw material medicine impurity detection devices, part of the residue will adhere to the inner wall of the detection device after the impurities in the raw material medicine are separated from the raw material liquid. The residue will react with air to form a hard block after a long period of contact with air, resulting in deviation of the detection result in the subsequent detection process of the liquid medicine impurities, thereby affecting the overall detection efficiency and quality. In order to solve this problem, an eribulin raw material medicine impurity detection device is proposed. SUMMARY

[0004] The utility model provides a kind of eribulin raw material medicine impurity detection device, it solves the problem in above-mentioned background technology.

[0005] The utility model solves its technical problem by adopting the following technical scheme:

[0006] An eribulin raw material medicine impurity detection device includes a mounting base and a detection cylinder body arranged on the mounting base. A detection groove for pouring raw material medicine is formed in the detection cylinder body. The top of the detection groove is open. A cleaning member is arranged in the detection groove. The cleaning member includes two cleaning side plates rotating along the circumference of the side wall of the detection groove. A connecting column is arranged on the side of the two cleaning side plates facing each other. A driving member is arranged in the middle of the connecting column for driving the cleaning side plates to rotate along the circumference of the side wall of the detection groove. Two discharge ports are symmetrically arranged in the cleaning side plates. The side of the discharge port is inclined to facilitate the discharge of residue from the side wall of the detection groove. A detection element for detecting impurities in the raw material medicine is arranged at the bottom of the detection groove.

[0007] Preferably, the driving member includes a rotating shaft arranged between the two connecting columns. A chuck is rotatably arranged at the bottom of the rotating shaft. The chuck and the bottom of the detection groove are detachably connected. Limiting structures are arranged between the chuck and the bottom of the detection groove.

[0008] Preferably, the limiting structure includes a plurality of clamping grooves formed on the outer circumference of the chuck. A limiting groove for clamping the chuck is formed in the bottom of the detection groove. Limiting protrusions are arranged near the clamping grooves of the limiting groove.

[0009] Preferably, the top of the rotating shaft is provided with a handle for the operator to rotate.

[0010] Preferably, the discharge port is distributed with a plurality of chopping cutter heads.

[0011] Preferably, the height of the cleaning side plate is the same as that of the detection groove.

[0012] The advantages and positive effects of the utility model are: through the installation of the base, the detection cylinder and the detection groove, the detection process can be carried out in a stable environment, and through the rotation of the cleaning side plate in the cleaning piece, the inner wall of the detection groove can be orderly scraped and cleaned after detection, so that the influence of residual impurities on the subsequent detection of the liquid medicine is avoided, so that the whole detection result is relatively accurate, and through the setting of the chuck, the whole cleaning piece can be conveniently disassembled and installed in the cleaning groove. BRIEF DESCRIPTION OF DRAWINGS

[0013] The utility model will be further described below in combination with the drawings and examples.

[0014] Figure 1 is the structural schematic diagram of the utility model;

[0015] Figure 2 is Figure 1 the structural schematic diagram of the cleaning side plate in the middle;

[0016] Figure 3 is Figure 1 the top view structural schematic diagram of the chuck in the middle.

[0017] The marks in the drawings are described as follows:

[0018] 1, installation base; 11, detection cylinder; 111, detection groove; 12, limiting groove; 121, limiting block; 122, detection device;

[0019] 2, cleaning piece; 21, rotating shaft; 211, chuck; 2111, clamping groove; 22, connecting column; 23, cleaning side plate; 231, discharge port; 232, chopping cutter head; 24, handle. DETAILED DESCRIPTION

[0020] The utility model will be further described below in combination with the drawings and examples.

[0021] The utility model example is further described in combination with the drawings:

[0022] Refer to Figure 1 and Figure 2 as well as Figure 3As shown, the impurity detection of eribulin raw material is a post-processing step in the drug solution, which can prevent excessive impurities from affecting the efficacy of eribulin raw material. In most existing eribulin raw material impurity detection devices, after some impurities in the raw material separate from the drug solution, some residue adheres to the inner wall of the detection device. Over time, this residue reacts with air to form hard lumps, leading to deviations in subsequent impurity detection, thus affecting overall detection efficiency and quality. To solve this problem, an eribulin raw material impurity detection device is proposed, including a mounting base 1 and a detection cylinder 11 mounted on the mounting base 1. The detection cylinder 11 has a detection groove 111 for pouring the raw material. The top of the detection groove 111 is open, and a cleaning component 2 is provided inside the detection groove 111. The cleaning component 2 includes two cleaning side plates 23 that rotate circumferentially along the periphery of the detection groove 111. A connecting post 22 is provided on one side of the cleaning side plates 23 that are close to each other. The middle section of the connecting post 22 is provided with a driving component for driving the cleaning side plates 23 to rotate circumferentially along the wall of the detection groove 111. Two discharge ports 231 are symmetrically opened in the upper and lower parts of the cleaning side plates 23. The sides of the discharge ports 231 are set in an inclined state to facilitate the discharge of residue from the side wall of the detection groove 111. The bottom of the detection groove 111 is also provided with a detection element 122 for detecting impurities in the raw material. The installation base 1, the detection cylinder 11, and the detection groove 111 can ensure that the detection process is carried out in a stable environment. The rotation of the cleaning side plates 23 in the cleaning component 2 can achieve the purpose of orderly scraping and cleaning of the inner wall of the detection groove 111 after the detection is completed, avoiding the influence of residual impurities on the subsequent detection of the drug solution, thereby making the overall detection result relatively accurate. The chuck 211 facilitates the disassembly and installation of the entire cleaning component 2 from the cleaning groove.

[0023] It should be noted that the specific structure of the above-mentioned driving component is as follows: the driving component includes a rotating shaft 21 disposed between the two connecting columns 22, and a chuck 211 is rotatably provided at the bottom of the rotating shaft 21. The chuck 211 is detachably connected to the bottom of the detection groove 111, and a limiting structure is provided between the chuck 211 and the bottom of the detection groove 111. The detachable connection between the chuck 211 and the bottom of the detection groove 111 allows the entire cleaning component 2 to be inserted into the detection groove 111 when it is necessary to clean the residue on the inner wall of the detection groove 111. At this time, the operator can rotate the rotating shaft 21 to achieve the purpose of cleaning the residue on the inner wall of the cleaning groove by the cleaning side plate 23. When it is necessary to detect impurities in the liquid through the detection groove 111, the cleaning component 2 can be disassembled.

[0024] The detection element 122 is a detection unit for detecting impurities of eribulin drug substance, and the specific detection structure is mature in the prior art, so it is not necessary to repeat it in the embodiment.

[0025] Further, after the residue on the inner wall of the cleaning groove is cleaned, the residue can be dropped out by tilting, and the specific structure of the limiting structure is that the limiting structure comprises a plurality of clamping grooves 2111 formed on the outer periphery of the chuck 211, a limiting groove 12 is formed in the bottom of the detection groove 111 for clamping the chuck 211, and a limiting protrusion 121 is arranged at the position close to the clamping groove 2111; the synchronous arrangement of the clamping grooves 2111 and the limiting protrusion 121 can ensure that the chuck 211 is clamped into the limiting groove 12 in order, and the chuck 211 and the rotating shaft 21 are rotatably connected, so as to ensure the stability of the rotating shaft 21 and the cleaning side plate 23 during rotation.

[0026] It should be noted that, in order to facilitate the operator to rotate the rotating shaft 21, the top of the rotating shaft 21 is provided with a handle 24 for the operator to rotate; the handle 24 can be used to rotate the rotating shaft 21, so as to clean the residue on the inner wall of the cleaning groove.

[0027] Further, the discharge port 231 is arranged to ensure that the cleaned residue can be dropped out through the discharge port 231 during the rotation and cleaning of the cleaning side plate 23, so as to ensure the stability of the cleaning process.

[0028] In addition, a plurality of chopping knife heads 232 are arranged in the discharge port 231; the arrangement of the chopping knife heads 232 can avoid the residue in block form.

[0029] It is worth mentioning that the side surface of the cleaning side plate 23 is also inclined to facilitate the cleaning of the residue on the inner wall of the cleaning groove.

[0030] In addition, the height of the entire cleaning side plate 23 and the detection groove 111 is matched, which is convenient for omnidirectional cleaning.

[0031] It should be noted that the embodiments of the utility model are illustrative rather than limiting, and therefore the utility model is not limited to the embodiments described in the specific embodiments, and any other embodiments derived from the technical solution of the utility model by those skilled in the art also belong to the protection scope of the utility model.

Claims

1. A device for detecting impurities in iribulin raw material, characterized in that: The device includes a mounting base (1) and a detection cylinder (11) mounted on the mounting base (1). The detection cylinder (11) has a detection groove (111) for pouring in raw materials. The top of the detection groove (111) is open. A cleaning component (2) is provided in the detection groove (111). The cleaning component (2) includes two cleaning side plates (23) that rotate circumferentially along the periphery of the detection groove (111). The two cleaning side plates (23) are close to each other on one side. A connecting column (22) is provided. The middle section of the connecting column (22) is provided with a driving component for driving the cleaning side plate (23) to rotate circumferentially along the periphery of the detection groove (111). Two discharge ports (231) are symmetrically opened in the upper and lower parts of the cleaning side plate (23). The sides of the discharge ports (231) are set in an inclined state to facilitate the discharge of residue from the side wall of the detection groove (111). The bottom of the detection groove (111) is also provided with a detection element (122) for detecting impurities in the raw drug.

2. The impurity detection device for eribulin raw material according to claim 1, characterized in that: The driving component includes a rotating shaft (21) disposed between the two connecting columns (22). A chuck (211) is rotatably provided at the bottom of the rotating shaft (21). The chuck (211) is detachably connected to the bottom of the detection groove (111), and the chuck (211) and the bottom of the detection groove (111) are provided with a limiting structure.

3. The impurity detection device for eribulin raw material according to claim 2, characterized in that: The limiting structure includes a plurality of slots (2111) formed on the outer periphery of the chuck (211), and the bottom of the detection slot (111) is recessed to form a limiting groove (12) for the chuck (211) to be inserted into. The limiting groove (12) is provided with a limiting protrusion (121) near the slot (2111).

4. The impurity detection device for eribulin raw material according to claim 2, characterized in that: The top of the rotating shaft (21) is provided with a handle (24) for the operator to rotate.

5. The impurity detection device for eribulin raw material according to claim 2, characterized in that: The discharge port (231) is provided with a number of shredding blades (232).

6. The impurity detection device for eribulin raw material according to claim 1, characterized in that: The height of the cleaning side plate (23) is the same as the height of the detection groove (111).