Protein purification column support frame

Abstract

The utility model relates to the technical field of protein purification columns, in particular to a protein purification column supporting frame. Comprising a transverse plate, a vertical plate and an adjusting mechanism, the adjusting mechanism comprises a threaded plate, an adjusting screw rod, locking knobs, a sliding plate, a positioning seat, a placing cylinder, a T-shaped seat and a clamping device, during use, the bottom end of the protein purification column is inserted into the placing cylinder and clamped and fixed through the clamping device to achieve placing, fixing and supporting, and further, the locking knobs on the two sides are unscrewed, so that the protein purification column is placed and supported. Then an adjusting screw rod is rotated, after the adjusting screw rod is rotated, a sliding plate is pushed to slide upwards, so that the height of the sliding plate can be adjusted, the height of the protein purification column can be adjusted, locking knobs on the two sides are screwed respectively after the adjustment is completed, and the arrangement of a positioning seat and a T-shaped seat can be beneficial to the realization of quick replacement of a placement barrel; furthermore, random adjustment can be carried out according to the heights of different detection personnel, and observation and detection of the detection personnel with different heights are facilitated.

Description

TECHNICAL FIELD

[0001] The utility model relates to protein purification column technical field especially, relate to a protein purification column support frame. BACKGROUND

[0002] Protein purification column is a kind of commonly used laboratory tool, is used to separate and purify target protein from mixed solution, it is based on molecular size, affinity or other interaction principle, utilizes the interaction between the filling in column and target protein to realize the purpose of separation and purification.

[0003] Through the retrieval, prior art CN222092587U discloses a protein purification column support frame, and relates to protein purification column technical field.The utility model discloses a frame body, the inner wall of frame body is fixedly connected with the partition, the upper side of partition is elastically matched with the receiving shell, the inner wall of frame body is rotationally matched with the worm, the lower side of receiving shell is fixedly connected with the rack that is slidably matched with partition, the worm is fixedly connected with the gear that is engaged with rack.The utility model discloses a rack is arranged, when protein purification column is placed into the receiving shell in frame body, under its dead weight, make receiving shell drive rack to move down, drive gear to rotate, gear rotation drives worm to rotate, under the transmission of worm wheel, make driving rod to rotate, under the transmission of transmission part, make driven rod drive connecting plate and clamping plate to rotate, so that clamping plate is clamped and fixed to protein purification column, when needing to take out, directly pull protein purification column, improve the fixed effect of protein purification column, and the convenience of access.

[0004] But the above-mentioned device has the following problems when using: the height of the device is fixed, so that the height of the observation window is also fixed, which is inconvenient for the observation of detection personnel with different heights. UTILITY MODEL CONTENTS

[0005] The utility model aims at providing a protein purification column support frame, can be adjusted randomly according to the height of different detection personnel, and it is beneficial to the observation of detection personnel with different heights.

[0006] To achieve the above object, the utility model provides a protein purification column support frame, including horizontal plate and vertical plate, the vertical plate is installed in the both sides of horizontal plate, still include adjusting mechanism;

[0007] The adjusting mechanism comprises a threaded plate, an adjusting screw rod, locking knobs, a sliding plate, positioning seats, a placing cylinder, a T-shaped seat and a clamping device, the threaded plate is detachably connected with the horizontal plate and is located at the bottom of the horizontal plate, the adjusting screw rod is threadedly connected with the threaded plate and penetrates through the threaded plate, and the top stepped end portion of the adjusting screw rod abuts against the bottom of the sliding plate, the locking knobs are arranged on both sides of the sliding plate and abut against the vertical plate, the sliding plate is slidably connected with the vertical plate, a plurality of the positioning seats are detachably connected with the sliding plate and are arranged in a linear interval, the T-shaped seat is detachably connected with the placing cylinder and is threadedly connected with the positioning seats and is located at the bottom of the placing cylinder, and the clamping device is arranged on the placing cylinder.

[0008] The clamping device comprises arc-shaped clamping plates and action assemblies, the arc-shaped clamping plates are six in number and are uniformly and annularly arranged in the placing cylinder, and the action assemblies are arranged on the side of the arc-shaped clamping plates close to the placing cylinder.

[0009] The action assembly comprises a guide rod and a spring member, the guide rod is integrally formed with the arc-shaped clamping plate and is slidably connected with the placing cylinder, and the spring member is arranged between the arc-shaped clamping plate and the placing cylinder.

[0010] The spring member comprises a reset spring and a tensioning screw rod, one side of the reset spring is welded to the inner wall of the placing cylinder and the other side abuts against the arc-shaped clamping plate, and the tensioning screw rod is T-shaped, is threadedly connected with the arc-shaped clamping plate and is slidably connected with the placing cylinder.

[0011] The protein purification column support frame further comprises a guiding mechanism, the guiding mechanism comprises round rods and limiting rings, the round rods are threadedly connected with the sliding plate and are slidably connected with the horizontal plate and are four in number, and the limiting rings are threadedly connected with the round rods and are located at the bottom of the round rods.

[0012] The protein purification column support frame of the utility model, when using, through the protein purification column bottom end is inserted in the placing cylinder and is clamped and fixed by the clamping device, the fixed and supported are realized, further, the locking knob of both sides is unscrewed, then the adjusting screw rod is rotated, the sliding plate is pushed up after the adjusting screw rod is rotated, thereby the height adjustment of the sliding plate can be realized, the height adjustment of the protein purification column is also realized, after the adjustment is completed, the locking knob of both sides is screwed respectively, through the setting of the positioning seat and the T-shaped seat, the quick replacement of the placing cylinder can be realized, then the height of the detection personnel can be adjusted at will, the detection personnel of different heights can be observed and detected. BRIEF DESCRIPTION OF DRAWINGS

[0013] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the accompanying drawings used in the description of the embodiments or the prior art will be briefly introduced below.

[0014] Figure 1 This is a schematic diagram of the overall structure of the protein purification column support frame according to the first embodiment of this utility model.

[0015] Figure 2 This is a schematic diagram of the structure of the threaded plate according to the first embodiment of this utility model.

[0016] Figure 3 This is a schematic diagram of the installation position of the T-shaped seat according to the first embodiment of this utility model.

[0017] Figure 4 This is a schematic diagram of the arc-shaped clamping plate according to the first embodiment of this utility model.

[0018] Figure 5 This is a schematic diagram of the overall structure of the protein purification column support frame according to the second embodiment of this utility model.

[0019] In the diagram: 101-Horizontal plate, 102-Vertical plate, 103-Threaded plate, 104-Adjusting screw, 105-Locking knob, 106-Slide plate, 107-Positioning seat, 108-Placement cylinder, 109-T-shaped seat, 110-Arc-shaped clamp, 111-Guide rod, 112-Reset spring, 113-Tightening screw, 201-Round rod, 202-Limiting ring. Detailed Implementation

[0020] The embodiments of the present invention are described in detail below. Examples of the embodiments are shown in the accompanying drawings. The embodiments described below with reference to the accompanying drawings are exemplary and intended to explain the present invention, but should not be construed as limiting the present invention.

[0021] Example 1:

[0022] like Figures 1 to 4 As shown, where Figure 1 This is a schematic diagram of the overall structure of a protein purification column support frame. Figure 2 This is a structural schematic diagram of threaded plate 103. Figure 3 This is a schematic diagram showing the installation position of the T-shaped bracket 109. Figure 4It is the structural schematic view of arc clamping plate 110, the utility model provides a kind of protein purification column support frame: including horizontal plate 101, vertical plate 102 and adjusting mechanism, the adjusting mechanism includes threaded plate 103, adjusting screw 104, locking knob 105, sliding plate 106, positioning seat 107, placing cylinder 108, T-shaped seat 109 and clamping device, the clamping device includes arc clamping plate 110 and action assembly, the action assembly includes guide rod 111 and spring member, the spring member includes return spring 112 and tensioning screw 113. According to the height of different detection personnel, the foregoing scheme can be adjusted randomly, and it is beneficial for detection personnel of different heights to observe detection. It can be understood that the foregoing scheme can facilitate detection personnel of different heights to observe detection.

[0023] In the embodiment, the vertical plate 102 is installed on both sides of the horizontal plate 101, and the vertical plate 102 is connected with the horizontal plate 101 through positioning pins and bolts. The vertical plate 102 is used for supporting when placing.

[0024] The threaded plate 103 is detachably connected with the horizontal plate 101 and located at the bottom of the horizontal plate 101. The adjusting screw 104 is threadedly connected with the threaded plate 103 and penetrates through the threaded plate 103. The top stepped end of the adjusting screw 104 abuts against the bottom of the sliding plate 106. The locking knob 105 is arranged on both sides of the sliding plate 106 and abuts against the vertical plate 102. The sliding plate 106 is slidably connected with the vertical plate 102. A plurality of positioning seats 107 are detachably connected with the sliding plate 106 and arranged in a linear interval. The T-shaped seat 109 is detachably connected with the placing cylinder 108 and threadedly connected with the positioning seat 107. The T-shaped seat 109 is located at the bottom of the placing cylinder 108. The clamping device is arranged on the placing cylinder 108. The threaded plate 103 is fixed at the bottom of the two horizontal plates 101 through positioning pins and bolts and is provided with a penetrating threaded hole for rotationally cooperating with the adjusting screw 104. The adjusting screw 104 is T-shaped. The top stepped portion can abut against the bottom of the sliding plate 106. The sliding plate 106 is provided with a guide stepped portion on both sides. The guide stepped portion is slidably matched with a limiting sliding groove on the vertical plate 102 and is provided with an external threaded end on the outer side for mounting the locking knob 105. The positioning seat 107 is fixed through a countersunk bolt. A threaded cavity is arranged on the positioning seat 107 for mounting the external threaded end of the T-shaped seat 109. The T-shaped seat 109 is connected with the bottom of the placing cylinder 108 through a countersunk bolt. A matching cavity matched with the bottom of the protein purification column is arranged at the bottom of the placing cylinder 108. The clamping device cooperates with the placing cylinder 108 to fix the protein purification column and facilitate direct removal of the protein purification column.

[0025] Secondly, the number of the arc-shaped clamping plates 110 is six, and the arc-shaped clamping plates 110 are uniformly and annularly arranged in the placing cylinder 108; the action assembly is arranged on the side of the arc-shaped clamping plate 110 close to the placing cylinder 108. The arc-shaped clamping plate 110 is used for abutting at the bottom of the protein purification column to realize fixing, and the action assembly is used for cooperating with fixing.

[0026] Then, the guide rod 111 is integrally formed with the arc-shaped clamping plate 110 and is in sliding connection with the placing cylinder 108; the spring member is arranged between the arc-shaped clamping plate 110 and the placing cylinder 108. The guide rod 111 can slide on the placing cylinder 108, and the spring member is used for clamping cooperation.

[0027] Finally, one side of the reset spring 112 is welded on the inner wall of the placing cylinder 108, and the other side abuts on the arc-shaped clamping plate 110; the tensioning screw 113 is T-shaped, is in threaded connection with the arc-shaped clamping plate 110, and is in sliding connection with the placing cylinder 108. One side of the reset spring 112 is welded on the arc-shaped inner wall of the placing cylinder 108, and the other side abuts on the outer side of the positioning column on the arc-shaped clamping plate 110. A threaded connection hole is arranged on the positioning column, so that the tensioning screw 113 is convenient to install and disassemble. The tensioning screw 113 is used for limiting.

[0028] In use, the bottom end of the protein purification column is inserted into the placing cylinder 108, after insertion, the arc-shaped clamping plate 110 acts and compresses the reset spring 112, at the same time, the guide rod 111 and the tensioning screw 113 slide, after being completely put in, the reset spring 112 is reset to clamp and fix the protein purification column. Further, the locking knobs 105 on the two sides are loosened, then the adjusting screw 104 is rotated, the adjusting screw 104 is rotated to drive the sliding plate 106 to slide upwards, so that the height of the sliding plate 106 can be adjusted, and the height of the protein purification column can also be adjusted. After adjustment, the locking knobs 105 on the two sides are tightened, respectively. The setting of the positioning seat 107 and the T-shaped seat 109 can facilitate the quick replacement of the placing cylinder 108. Different sizes or damaged placing cylinders 108 can be directly replaced, so that the height of the protein purification column can be adjusted according to the height of different detection personnel, and the detection of detection personnel of different heights can be observed.

[0029] Embodiment two:

[0030] As shown in the drawings, Figure 5 the arc-shaped clamping plate 110 is arranged in the placing cylinder 108, and the action assembly is arranged on the side of the arc-shaped clamping plate 110 close to the placing cylinder 108. Figure 5It is the overall structure schematic view of protein purification column support frame, on the basis of first embodiment, the utility model provides a protein purification column support frame, the protein purification column support frame still includes guiding mechanism, the guiding mechanism includes round bar 201 and limit ring 202.

[0031] Among them, the round bar 201 is connected with the sliding plate 106 by screw thread, and is connected with the cross plate 101 by sliding, and the number is four;The limit ring 202 is connected with the round bar 201 by screw thread, and is located at the bottom of the round bar 201.The outer thread end of the top of the round bar 201 is directly connected with the threaded hole at the bottom of the sliding plate 106, and is installed and matched, the sliding hole is set on the cross plate 101, the wear-resistant coating of 0.3mm thickness is set on the inner surface of sliding hole, which is beneficial to improve the service life of the cross plate 101, the limit ring 202 is directly installed on the outer thread installation end at the bottom of the round bar 201, when the sliding plate 106 slides to the highest position, the limit ring 202 will abut on the bottom of the cross plate 101.

[0032] In the embodiment, the stability of the vertical movement of the sliding plate 106 can be further improved by the four groups of the round bar 201 and the limit ring 202 structure.

[0033] The above disclosed is only one or more preferred embodiments of the application, which cannot limit the scope of the application, and those skilled in the art can understand that all or part of the above-mentioned embodiments can be implemented, and equivalent changes made according to the claims of the application still belong to the scope covered by the application.

Claims

1. A protein purification column support frame, comprising a horizontal plate and a vertical plate, the vertical plate being installed on both sides of the horizontal plate, characterized in that: It also comprises an adjusting mechanism; The adjusting mechanism comprises a threaded plate, an adjusting screw, a locking knob, a sliding plate, a positioning seat, a placing cylinder, a T-shaped seat and a clamping device, the threaded plate is detachably connected with the horizontal plate and located at the bottom of the horizontal plate, the adjusting screw is threadedly connected with the threaded plate and penetrates through the threaded plate, and the top stepped end of the adjusting screw abuts against the bottom of the sliding plate, the locking knob is arranged on both sides of the sliding plate and abuts against the vertical plate, the sliding plate is slidably connected with the vertical plate, a plurality of positioning seats are detachably connected with the sliding plate and arranged in a linear interval, the T-shaped seat is detachably connected with the placing cylinder and threadedly connected with the positioning seat and located at the bottom of the placing cylinder, and the clamping device is arranged on the placing cylinder.

2. The protein purification column support frame according to claim 1, characterized in that: The clamping device comprises arc-shaped clamping plates and an action assembly, the number of the arc-shaped clamping plates is six and they are uniformly and annularly spaced in the placing cylinder; and the action assembly is arranged on the side of the arc-shaped clamping plates close to the placing cylinder.

3. The protein purification column support frame according to claim 2, characterized in that: The action assembly comprises a guide rod and a spring member, the guide rod is integrally formed with the arc-shaped clamping plate and slidably connected with the placing cylinder; and the spring member is arranged between the arc-shaped clamping plate and the placing cylinder.

4. The protein purification column support frame according to claim 3, characterized in that: The spring member comprises a return spring and a tensioning screw, one side of the return spring is welded to the inner wall of the placing cylinder and the other side abuts against the arc-shaped clamping plate; and the tensioning screw is T-shaped, threadedly connected with the arc-shaped clamping plate and slidably connected with the placing cylinder.

5. The protein purification column support rack of claim 1, wherein : The protein purification column support frame further comprises a guide mechanism, the guide mechanism comprises a round rod and a limiting ring, the number of the round rods is four, the round rods are threadedly connected with the sliding plate and slidably connected with the horizontal plate; and the limiting ring is threadedly connected with the round rod and located at the bottom of the round rod.

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