Culture bottle capable of pouring liquid without residue
By adding a shoulder step and a bottom plate limiting rod to the lower part of the outer perimeter of the culture bottle mouth, combined with a downward pressure limiting component, the problems of residual culture medium and shaking during the pouring and transfer process are solved, thus achieving the stability and safety of the culture bottle.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- LUOYANG FUDAU BIOTECHNOLOGY CO LTD
- Filing Date
- 2025-04-23
- Publication Date
- 2026-04-10
AI Technical Summary
Existing polystyrene plastic cell culture roller bottles suffer from uneven dispersal of the adhesive material at the shoulder of the bottle neck during blow molding, which easily leads to residue when the culture medium is poured out. Furthermore, the bottles are prone to shaking and loosening of the caps during transfer, affecting operational safety and efficiency.
A shoulder step is added to the lower part of the outer perimeter of the culture bottle mouth. Combined with the limiting upright and the downward pressure limiting component on the base plate, the even blowing and stable transfer of the bottle mouth are ensured by threaded engagement and locking screws to prevent liquid residue and shaking.
This method achieves zero-residue pouring of culture medium, ensuring the stability and safety of the culture flask during the transfer process, and improving the convenience and safety of operation.
Smart Images
Figure CN224105839U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to cell culture bottle auxiliary assembly field, concretely relates to a culture bottle without liquid residual. BACKGROUND
[0002] In adherent cell culture, cell culture roller bottle is one of indispensable tools. The selection of suitable roller bottle material is very important for the success of cell culture. In the prior art, the common choices include glass and polystyrene plastic. The glass cell roller bottle needs to go through a series of complicated cleaning, sterilization and drying procedures before use, while the polystyrene plastic cell roller bottle is ready to use after disassembly, which is more convenient to operate and can improve work efficiency. At the same time, during the operation of handling, cleaning and drying, the glass cell roller bottle is easy to break, increasing the cost and possibly causing safety hazards. The polystyrene plastic material has good drop resistance and is not easy to break, so it is more safe and durable. Therefore, the cell culture roller bottle made of polystyrene plastic material is widely used
[0003] The existing cell culture roller bottle made of polystyrene plastic material is usually made by injection blow molding process. However, due to the uneven distribution of glue during the blow molding process of the existing bottle mouth shoulder position, the inside of the bottle mouth position of the culture bottle will have a reverse buckle, which will cause liquid residue in the bottle during the subsequent pouring process. UTILITY MODEL CONTENTS
[0004] The utility model aims at solving the above problems and provides a culture bottle without liquid residual, which is described in detail below.
[0005] To achieve the above purpose, the utility model provides the following technical scheme:
[0006] The utility model provides a culture bottle without liquid residual, which comprises a cell culture bottle body and a bottom plate. A shoulder step is added to the lower part of the periphery of the bottle mouth of the cell culture bottle body. A bottle cap is detachably combined with the bottle mouth of the cell culture bottle body by thread cooperation.
[0007] The cell culture bottle body is placed on the top surface of the bottom plate. The outer periphery of the bottom plate extends a plurality of flaps. The top surface of each flap is vertically fixed with a limiting vertical rod. The cell culture bottle body is placed vertically between a plurality of limiting vertical rods and on the bottom plate to prevent the cell culture bottle body from shaking and falling.
[0008] A downward limiting component is detachably combined between the top parts of the limiting vertical rods on both sides to prevent the bottle cap from loosening accidentally and the bottle body from shaking greatly during transfer.
[0009] As preferred, the shoulder step is an integral annular flange.
[0010] As preferred, the shoulder step has an outer diameter of φ49 and the bottle cap has an outer diameter of φ53.
[0011] As preferred, the cell culture bottle body is a polystyrene plastic roller bottle with a capacity of 2L.
[0012] As preferred, the number of the wings and the number of the limiting vertical rods are both four and are circumferentially distributed, and the cell culture bottle body is placed between the limiting vertical rods in a vertical sliding fit manner.
[0013] As preferred, the pressing limiting assembly comprises a pressing cap, a clamp member and a side plate, the lower part of the pressing cap is open, the pressing cap is coaxially pressed on the top surface of the bottle cap, the clamp member is coaxially fixed on the periphery of the pressing cap, the side plates are fixed on the two sides of the clamp member and extend outward, the top surface of the side plate on both sides is vertically provided with a matching hole, the top surface of the side plate is coaxially fixed with a matching sleeve at the position of the matching hole, the limiting vertical rods are vertically slidably arranged through the corresponding matching hole and matching sleeve on the same side, the front surface of the matching sleeve is radially provided with a mounting hole, the mounting hole is a through hole, and the mounting hole is coaxially provided with a locking screw through a threaded fit.
[0014] As preferred, the pressing cap is a circular cap with an open lower part, and the pressing cap is coaxially slidably arranged with the bottle cap.
[0015] As preferred, the outer end of the locking screw is coaxially fixed with a force applying end.
[0016] As preferred, the locking screw is a plastic screw member.
[0017] As preferred, the top end of the limiting vertical rod is higher than the top surface of the bottle cap.
[0018] The utility model discloses a cell culture bottle body, which is characterized by the following: a shoulder step is arranged at the lower part of the periphery of the bottle mouth of the cell culture bottle body, and the shoulder step is an integral annular flange, which can help the uniform dispersion of the glue at the shoulder position of the bottle mouth, avoid the reverse buckling of the inside of the bottle mouth of the cell culture bottle body, and ensure that no liquid remains when the culture solution is poured out.
[0019] The utility model discloses a cell culture bottle body, which is characterized by the following: a shoulder step is arranged at the lower part of the periphery of the bottle mouth of the cell culture bottle body, and the shoulder step is an integral annular flange, which can help the uniform dispersion of the glue at the shoulder position of the bottle mouth, avoid the reverse buckling of the inside of the bottle mouth of the cell culture bottle body, and ensure that no liquid remains when the culture solution is poured out.
[0020] 2. The plurality of wings are horizontally arranged at the outer periphery of the base plate, and the top surface of each wing is vertically fixed with a limiting vertical rod. Then, the cell culture bottle body is vertically arranged between the plurality of limiting vertical rods and on the base plate through the vertical sliding cooperation mode, which can prevent the cell culture bottle body from shaking and falling during the transfer process, and ensures that the cell culture bottle body can be stably transferred.
[0021] 3. The lower pressing limiting assembly is combined between the top portions of the limiting vertical rods at both sides to prevent the bottle cap from accidentally loosening and the bottle body from shaking greatly during the transfer process. Then, the cap top is pressed by the gland of the lower pressing limiting assembly, and the locking screw is tightened, which can prevent the bottle cap from accidentally loosening and the bottle body from shaking greatly during the transfer process, and further ensures that the cell culture bottle body can be stably transferred.
[0022] 4. The lower pressing limiting assembly can be quickly combined between the limiting vertical rods at both sides through the vertical sliding cooperation of the matching sleeve and the limiting vertical rod and the tightening of the locking screw. Meanwhile, the matching sleeve can be vertically slid and separated from the top end of the limiting vertical rod after the locking screw is loosened, so that the lower pressing limiting assembly can be separated from the limiting vertical rods at both sides. The combination and separation of the lower pressing limiting assembly between the limiting vertical rods at both sides are simple and easy to implement, which facilitates the use of the lower pressing limiting assembly after being combined between the limiting vertical rods at both sides, and facilitates the subsequent separate storage of the lower pressing limiting assembly after being separated from the limiting vertical rods at both sides and the smooth taking of the cell culture bottle body. BRIEF DESCRIPTION OF DRAWINGS
[0023] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings needed to be used in the embodiments or the prior art description. Obviously, the drawings in the following description are only some embodiments of the present application, and those skilled in the art can obtain other drawings according to these drawings without any creative effort.
[0024] Figure 1 is the overall isometric view of the present application;
[0025] Figure 2 is the sectional view of the present application Figure 1 ;
[0026] Figure 3 is the sectional view of the present application Figure 1 ;
[0027] Figure 4 is the front view of the present application Figure 1 ;
[0028] Figure 5 is the front view of the present applicationFigure 1 a left view schematic diagram of the present application;
[0029] Figure 6 the present application Figure 1 a top view schematic diagram of the present application.
[0030] The reference signs are explained as follows:
[0031] 1, down pressure limit assembly; 101, gland; 102, hoop member; 103, side plate; 104, matching sleeve; 105, mounting hole; 106, locking screw; 107, force end; 108, matching hole; 2, cell culture bottle body; 201, bottle cap; 202, shoulder step; 3, bottom plate; 301, limit vertical rod; 302, wing piece. DETAILED DESCRIPTION
[0032] In order to make the purpose, technical scheme and advantages of the present application more clear, the technical scheme of the present application will be described in detail below. Obviously, the described embodiments are only part of the embodiments of the present application, not all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor are within the scope of the present application.
[0033] Referring to Figures 1-6 The present application provides a culture bottle without liquid residue, which comprises a cell culture bottle body 2 and a bottom plate 3. The lower part of the periphery of the bottle mouth of the cell culture bottle body 2 is additionally provided with a shoulder step 202, which is an integral annular flange. The bottle mouth of the cell culture bottle body 2 is detachably combined with a bottle cap 201 by thread cooperation. The advantages of this arrangement are that the setting of the shoulder step 202 can help the uniform blowing of the glue at the shoulder position of the bottle mouth, avoiding the occurrence of reverse buckling inside the bottle mouth of the cell culture bottle body 2, and ensuring that there is no liquid residue when the cell culture bottle body 2 pours out the culture solution. The cell culture bottle body 2 is placed on the top surface of the bottom plate 3. The outer periphery of the bottom plate 3 extends a plurality of wing pieces 302, and the top surface of each wing piece 302 is vertically fixed with a limit vertical rod 301. The purpose of this arrangement is to prevent the cell culture bottle body 2 from shaking and falling by placing it between a plurality of limit vertical rods 301 and on the bottom plate 3.
[0034] Referring to Figures 1-6As shown, the lower pressing limiting assembly 1 is detachably combined between the top of the limiting vertical rods 301 at both sides to prevent the bottle cap 201 from loosening and the bottle body from shaking greatly during the transfer process. Specifically, the lower pressing limiting assembly 1 comprises a pressing cap 101, a clamp piece 102, and a side plate 103. The lower part of the pressing cap 101 is open, and the pressing cap 101 is coaxially pressed on the top surface of the bottle cap 201. The clamp piece 102 is coaxially fixed on the periphery of the pressing cap 101, and the side plate 103 is fixed on the periphery of the clamp piece 102 at both sides and extends outward horizontally. The top surface of the side plate 103 at both sides is vertically provided with a cooperating hole 108, and the top surface of the side plate 103 is coaxially fixed with a cooperating sleeve 104 at the position of the cooperating hole 108. The limiting vertical rod 301 passes through the corresponding cooperating hole 108 and cooperating sleeve 104 at the same side in a vertically sliding manner. The front surface of the cooperating sleeve 104 is radially provided with a mounting hole 105, which is a through hole and is coaxially provided with a locking screw 106 through threaded cooperation. In this way, firstly, the pressing cap 101 of the lower pressing limiting assembly 1 is pressed on the top of the bottle cap 201, and the locking screw 106 is tightened, which can prevent the bottle cap 201 from loosening and the bottle body from shaking greatly during the transfer process. At the same time, the lower pressing limiting assembly 1 can be quickly combined between the limiting vertical rods 301 at both sides by vertically sliding the cooperating sleeve 104 and the limiting vertical rod 301 and tightening the locking screw 106. Only the locking screw 106 needs to be loosened to make the cooperating sleeve 104 vertically slide off the top end of the limiting vertical rod 301, so that the lower pressing limiting assembly 1 can be detached from the limiting vertical rods 301 at both sides. The combination and detachment of the lower pressing limiting assembly 1 between the limiting vertical rods 301 at both sides are simple and easy to implement.
[0035] Referring to Figures 1-3 As shown, the outer diameter specification of the shoulder step 202 is φ49, and the outer diameter specification of the bottle cap 201 is φ53, so that the specifications and sizes of the shoulder step 202 and the bottle cap 201 can meet the design needs. It should be noted that the bottle cap 201 should be pressed on the top surface of the shoulder step 202 when tightened. Further, the cell culture flask body 2 is a polystyrene plastic roller bottle with a capacity of 2L, so that the cell culture flask body 2 has material properties and capacity that meet the needs of cell adherent culture. Furthermore, the number of the wing plates 302 and the limiting vertical rods 301 is four, which are circumferentially distributed. The cell culture flask body 2 is placed between the limiting vertical rods 301 in a vertically sliding manner, so that the cell culture flask body 2 can be stably positioned on the top surface of the bottom plate 3.
[0036] Referring to Figures 1-6As shown, specifically to the pressing limiting assembly 1, the pressing cover 101 is a circular cover with an open lower part, and the pressing cover 101 is coaxially and slidingly matched with the bottle cap 201, so that the pressing cover 101 can press the bottle cap 201 from the top in a more closely matched manner. Meanwhile, optionally, the outer ends of the locking screws 106 are coaxially and fixedly connected with the force applying end heads 107, so that the locking screws 106 can be twisted by holding the force applying end heads 107. Further optionally, the locking screws 106 are plastic screw members, so that the locking screws 106 can meet the use requirements and be conveniently selected and matched. Further, the top ends of the limiting vertical rods 301 are higher than the top surface of the bottle cap 201, so that firstly, the limiting vertical rods 301 on both sides can be combined with the pressing limiting assembly 1 smoothly, and meanwhile, the pressing limiting assembly 1 can be located at a height higher than the bottle cap 201 to press the bottle cap 201.
[0037] With the above structure, in the use of the cell culture bottle body 2, because the shoulder step 202 is added to the lower part of the periphery of the bottle mouth of the cell culture bottle body 2, and the shoulder step 202 is an integral annular flange, then the setting of the shoulder step 202 can help the uniform dispersion of the glue at the bottle mouth shoulder position, avoiding the occurrence of the reverse buckle inside the bottle mouth of the cell culture bottle body 2, ensuring that the cell culture bottle body 2 will not have liquid residue when pouring the culture solution. Because the multiple wings 302 extend horizontally around the bottom plate 3, and the top surfaces of the wings 302 are vertically fixed with the limiting vertical rods 301, then the cell culture bottle body 2 can be placed vertically between the multiple limiting vertical rods 301 and on the bottom plate 3 through the vertical sliding fit mode, which can prevent the cell culture bottle body 2 from shaking and falling during the transfer process, ensuring that the cell culture bottle body 2 can be transferred stably. Because the lower pressing limiting assembly 1 is combined between the top parts of the limiting vertical rods 301 on both sides to prevent the bottle cap 201 from loosening accidentally and the bottle body from shaking greatly during the transfer process, then the bottle cap 201 can be prevented from loosening accidentally and the bottle body from shaking greatly during the transfer process by pressing the top part of the bottle cap 201 with the gland 101 of the lower pressing limiting assembly 1 and tightening the locking screw 106, which further ensures that the cell culture bottle body 2 can be transferred stably. Because the lower pressing limiting assembly 1 can be quickly combined between the limiting vertical rods 301 on both sides through the vertical sliding fit of the cooperating sleeve 104 with the limiting vertical rods 301 and the tightening of the locking screw 106, and the cooperating sleeve 104 can vertically slide off the top end of the limiting vertical rod 301 by loosening the locking screw 106, the lower pressing limiting assembly 1 can be separated from the limiting vertical rods 301 on both sides, and the combination and separation of the lower pressing limiting assembly 1 between the limiting vertical rods 301 on both sides are simple and easy to implement, which facilitates the use of the lower pressing limiting assembly 1 after being combined between the limiting vertical rods 301 on both sides, and facilitates the subsequent separate storage of the lower pressing limiting assembly 1 after being separated from the limiting vertical rods 301 on both sides and the smooth removal of the cell culture bottle body 2.
[0038] The above is only a specific implementation of the present application, but the protection scope of the present application is not limited thereto. Any skilled person in the art can easily think of changes or replacements within the technical range disclosed by the present application, which should be covered by the protection scope of the present application. Therefore, the protection scope of the present application should be subject to the protection scope of the claims.
Claims
1. A liquid transfer residue-free culture flask comprising a cell culture flask body (2) and a base plate (3), characterized in that: The cell culture bottle body (2) is additionally provided with a shoulder step (202) at the lower part of the bottle mouth periphery, and the bottle mouth of the cell culture bottle body (2) is detachably combined with a bottle cap (201) through thread cooperation. The cell culture bottle body (2) is placed on the top surface of the bottom plate (3), the outer periphery of the bottom plate (3) is extended with a plurality of flaps (302), and the top surfaces of the flaps (302) are vertically fixed with limiting vertical rods (301) for preventing the cell culture bottle body (2) from shaking and toppling by placing the cell culture bottle body (2) between a plurality of limiting vertical rods (301) and on the bottom plate (3). The lower pressing limiting assembly (1) is detachably combined between the top parts of the limiting vertical rods (301) at both sides to prevent the bottle cap (201) from accidentally loosening and the bottle body from shaking greatly during transfer.
2. The liquid dispensing residue-free culture flask of claim 1, wherein: The shoulder step (202) is an integral annular flange.
3. The liquid dispensing residue-free culture flask of claim 1, wherein: The outer diameter specification of the shoulder step (202) is φ49, and the outer diameter specification of the bottle cap (201) is φ53.
4. The liquid dispensing residue-free culture flask of claim 1, wherein: The cell culture bottle body (2) is a polystyrene plastic transfer bottle with a capacity of 2L.
5. The liquid pouring and residue free culture flask according to any one of claims 1-4, wherein: The number of the flaps (302) and the limiting vertical rods (301) is four, and they are circumferentially distributed, and the cell culture bottle body (2) is placed between a plurality of limiting vertical rods (301) in a vertical sliding fit.
6. The liquid dispensing residue-free culture flask of claim 5, wherein: The lower pressing limiting assembly (1) includes a gland (101), a clamp member (102), and a side plate (103). The lower part of the gland (101) is open, and the gland (101) is coaxially pressed on the top surface of the bottle cap (201). The outer periphery of the gland (101) is coaxially fixed with the clamp member (102), and the two sides of the clamp member (102) are fixed with the side plates (103) extending outward. The top surfaces of the side plates (103) at both sides are vertically provided with cooperating holes (108), and the top surfaces of the side plates (103) are coaxially fixed with cooperating sleeves (104) at the positions of the cooperating holes (108). The limiting vertical rods (301) are vertically slidably fitted through the corresponding cooperating holes (108) and cooperating sleeves (104) on the same side. The front surfaces of the cooperating sleeves (104) are radially provided with mounting holes (105), which are through holes, and the mounting holes (105) are coaxially provided with locking screws (106) through thread cooperation.
7. The liquid dispensing residue-free culture flask of claim 6, wherein: The gland (101) is a circular cap with an open lower part, and the gland (101) is coaxially slidably fitted with the bottle cap (201).
8. The liquid dispensing residue-free culture flask of claim 6, wherein: The outer ends of the locking screws (106) are coaxially fixed with force applying end heads (107).
9. The liquid dispensing residue-free culture flask of claim 6, wherein: The locking screws (106) are plastic screw members.
10. The liquid dispensing residue-free culture flask of claim 6, wherein: The top ends of the limiting vertical rods (301) are higher than the top surface of the bottle cap (201).