High-sensitivity licapridol urine detection test paper

Abstract

The utility model relates to the technical field of test paper, and discloses high-sensitivity likapu urine test paper which comprises a detection box and a sealing cover body, a detection paper card is arranged in the detection box, a placing frame is arranged at the bottom in the detection box, a bearing column is fixedly installed in the middle of the sealing cover body, and a sample adding groove is formed in the upper portion of the bearing column. A plurality of inclined flowing pipes are fixedly mounted on the side surface, located in the detection box, of the bearing column, the flowing pipes are communicated with the inner bottom of the sample adding groove, one end, far away from the bearing column, of each flowing pipe is matched with the placement frame, an elastic sealing ring used for blocking the flowing pipes is arranged in the sample adding groove, and a plurality of observation openings matched with the placement frame are formed in the sealing cover body. According to the utility model, after the urine in the sample adding groove stands, the sealing ring is moved upwards, and the urine is guided into the plurality of placing frames through the flow pipe, so that the uniformity of the urine amount in each placing frame is ensured, the uniformity of the urine dispersed on the detection paper card is improved, and the sensitivity of the whole test paper is improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of test paper, specifically to a high sensitivity stand card polyurine test paper. BACKGROUND

[0002] The stand card polyurine test paper is a kind of in-vitro diagnostic tool for rapidly screening multiple health indicators in urine, and its core function is to detect trace biomarkers through high-sensitivity immunochromatography or chemical reaction, to provide reliable basis for preliminary screening of diseases.

[0003] Through the retrieval, such as patent publication No. CN210294072U, a multi-union urine detection card is disclosed, which comprises fixedly connected upper shell and lower shell, the upper shell is processed with a sample hole and a plurality of observation holes, the lower shell is processed with a leakage groove, a limiting groove and a diffusion channel, the leakage groove is in position and the sample hole position corresponds to each other, the limiting groove number, the position and the observation hole one-to-one correspondence, the leakage groove is uniformly provided with a through hole in the side wall, the through hole bottom is higher than the groove bottom position, one end of the diffusion channel is connected with the through hole, the other end is communicated with the corresponding limiting groove, the diffusion channel gradually reduces from the through hole end to the limiting groove end. The utility model can make the sample flow more evenly, without leakage, and realize one-time rapid detection of multiple urine detection items.

[0004] The above-mentioned patent has obvious beneficial effects, but there are still the following deficiencies in practical operation:

[0005] In the above-mentioned comparative document, when detecting, the urine to be detected is added through the leakage groove, and flows to the test paper strip in the limiting groove through the through hole, and the color of the test paper strip is observed through the observation hole after the urine and the test paper strip react, but in the actual situation, when the urine is added in the leakage groove in the above-mentioned comparative document, the liquid level will shake after the urine is added, which will cause the urine flow in each through hole to be different, and will cause the urine in one or more limiting grooves to be less, and when the urine is less, the sensitivity of the whole test device is reduced, therefore, the urine test paper needs to be improved in the field, so as to solve the defects of the prior art. UTILITY MODEL CONTENTS

[0006] In view of the deficiencies of the prior art, the utility model provides a high-sensitivity stand card polyurine test paper, which improves the uniformity of urine dispersion on the test paper card and improves the sensitivity of the whole test paper.

[0007] In order to achieve the above object, the utility model provides the following technical scheme: a high sensitivity vertical caprino urine test paper, including detection box and the sealing cover body connected on the upper portion of detection box, be equipped with a plurality of detection paper card for detecting in detection box, be equipped with a plurality of placing frame for placing detection paper card in the bottom of detection box, the middle position of sealing cover body is fixedly installed with bearing column, the upper portion of bearing column is provided with sample addition groove, the side of bearing column in detection box is fixedly installed with a plurality of oblique flow tubes, flow tube is communicated with the bottom of sample addition groove and the end away from bearing column is matched with placing frame, the inner bottom of sample addition groove is equipped with the sealing ring with elasticity and is used for plugging flow tube, a plurality of observation ports matched with placing frame are formed in sealing cover body.

[0008] Preferably, the horizontal height of the end of the flow tube close to the bearing column is higher than that of the end close to the placing frame, the end of the flow tube away from the bearing column extends to a position above the middle of the placing frame, and the upper side of the sealing ring is fixedly connected with symmetrical pull blocks.

[0009] Preferably, the sealing cover body is provided with a rotatable sealing plate, and a plurality of clearance openings matched with the observation ports are formed through the sealing plate.

[0010] Preferably, a sliding groove is formed in the upper portion of the sealing cover body, and the upper portion of the sealing plate is provided with a plurality of rotating columns matched with the sliding groove.

[0011] Preferably, the lower portion of the placing frame is fixedly connected with a plug-in column, and a plurality of plug-in grooves matched with the plug-in column are formed in the bottom of the detection box.

[0012] Preferably, a plurality of elastic plates are fixedly installed on the side of the sealing cover body, one side of the elastic plate is provided with a clamping boss, and a clamping groove matched with the clamping boss is formed in the side of the detection box.

[0013] Preferably, arc-shaped grooves are formed in the opposite sides of the detection box and the sealing cover body, and elastic sealing rings are embedded in the arc-shaped grooves.

[0014] In view of the deficiencies of the prior art, the utility model provides a high sensitivity vertical caprino urine test paper, which overcomes the deficiencies of the prior art, and has the following beneficial effects:

[0015] 1. In the utility model, after the urine in the sample addition groove is stationary, the sealing ring is moved upward, the urine is guided to a plurality of placing frames through the flow tube, the uniformity of the urine amount in each placing frame is ensured, the urine is guided to the middle position of the detection paper card by the flow tube, the uniformity of the urine dispersion on the detection paper card is improved, and the sensitivity of the overall test paper is improved.

[0016] 2. In the utility model, the sealing plate can be rotated to close a plurality of observation ports, thereby improving the protection, dustproof effect and moisture-proof effect of the detection paper card.

[0017] 3、The utility model discloses, the plug -in column of placing frame lower part is inserted in the plug -in slot can install placing frame, can change the placing frame of different detection paper card and adapt the size, improve the application scope of overall device.

[0018] Other features and advantages of the present utility model will be set forth in the following description of the utility model, and in part will become apparent from the description, or be learned by practice of the present utility model. The purpose and other advantages of the present utility model can be realized and obtained by the structure indicated in the description, claims and drawings. BRIEF DESCRIPTION OF DRAWINGS

[0019] The accompanying drawings are included to provide a further understanding of the present utility model, and constitute a part of the specification, explain the present utility model together with embodiments of the present utility model, and do not constitute the limitation to the present utility model.

[0020] Figure 1 It is the structure schematic diagram of the whole of the utility model;

[0021] Figure 2 It is the structure schematic diagram of the whole of the utility model;

[0022] Figure 3 It is Figure 2 The enlarged structure schematic diagram of place A in middle;

[0023] Figure 4 It is Figure 2 The enlarged structure schematic diagram of place B in middle;

[0024] Figure 5 It is Figure 2 The enlarged structure schematic diagram of place C in middle;

[0025] Figure 6 It is Figure 2 The enlarged structure schematic diagram of place D in middle.

[0026] In the drawing: 1, detection box;2, sealing cover;3, detection paper card;4, placing frame;5, bearing column;6, sample adding groove;7, flow pipe;8, sealing ring;9, observation port;10, sealing plate;11, let -out mouth;12, sliding groove;13, rotating column;14, plug -in column;15, plug -in slot;16, elastic plate;17, clamping boss;18, clamping groove;19, arc slot;20, sealing ring;21, pull block. DETAILED DESCRIPTION

[0027] Clearly, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments of the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0028] Please refer to Figures 1-6 A high-sensitivity vertical cap urine test paper, comprising a detection box 1 and a sealing cover 2 connected to the upper part of the detection box 1, a plurality of detection paper cards 3 for detection are arranged in the detection box 1, a plurality of placement frames 4 for placing the detection paper cards 3 are arranged at the bottom of the detection box 1, a bearing column 5 is fixedly installed at the middle position of the sealing cover 2, a sample adding groove 6 is formed in the upper part of the bearing column 5, a plurality of inclined flow pipes 7 are fixedly installed on the side of the bearing column 5 in the detection box 1, the flow pipes 7 are in communication with the inner bottom of the sample adding groove 6 and the end away from the bearing column 5 is matched with the placement frame 4, an elastic sealing ring 8 for sealing the flow pipes 7 is arranged in the sample adding groove 6, a plurality of observation holes 9 matched with the placement frame 4 are formed in the sealing cover 2, the horizontal height of the end close to the bearing column 5 of the flow pipe 7 is higher than that of the end close to the placement frame 4, the end away from the bearing column 5 of the flow pipe 7 extends to the position above the middle of the placement frame 4, and symmetrically pulling blocks 21 are fixedly connected to the upper side of the sealing ring 8.

[0029] Specifically, the detection paper card 3 is a known standing Caprini urine detection test paper, the detection paper card 3 is provided with a gold mark pad and an NC film coating, the gold mark pad is mixed with fluorescent microspheres (emission wavelength 550nm) at a ratio of 1:5 through nano gold particles (particle size 20nm), monoclonal antibody (concentration 1mg / mL) is added, 4℃ incubation is carried out for 12h, the antibody mixture (antibody A: antibody B = 1:1, concentration 0.5mg / mL) is sprayed on the detection line area of the detection paper card 3, and 37℃ drying is carried out for 2h to generate the NC film coating, and the finished detection paper card 3 is placed in the placement frame 4, the shape of the placement frame 4 is matched with the shape of the detection paper card 3, the sealing cover 2 is connected to the upper part of the detection box 1 to complete the assembly of the whole detection paper, when it is needed to detect urine, the morning urine sample is collected, centrifugation is carried out to remove the precipitate, and dilution is carried out with PBS to different concentration gradients, the elastic sealing ring 8 is inserted into the sample adding groove 6, the elastic sealing ring 8 seals the end of the flow pipe 7, the quantitative urine sample is poured or dripped into the sample adding groove 6, and waiting is carried out until the urine is static, the sealing ring 8 is pulled upwards through the pull block 21, when the sealing ring 8 is pulled upwards, the urine flows to the middle position of the detection paper card 3 in the placement frame 4 through the flow pipe 7, and after standing for a specified time, the color of the detection paper card 3 is observed and compared through the observation port 9, the above-mentioned mode guarantees the uniformity of the urine amount in each placement frame 4, the flow pipe 7 guides the urine to the middle position of the detection paper card 3, the uniformity of the urine when being dispersed on the detection paper card 3 is improved, the sensitivity of the whole detection paper is improved, the detection paper card 3 can be a detection paper card 3 with different functions, different functions of the urine are detected, a plurality of functions of detection are realized at one time, and the efficiency of detecting the urine is improved.

[0030] As a technical optimization scheme of the utility model, the sealing cover 2 is provided with a rotatable sealing plate 10, a plurality of accommodating openings 11 matched with the observation ports 9 are arranged through the sealing plate 10, a sliding groove 12 is arranged on the upper part of the sealing cover 2, a plurality of rotating columns 13 matched with the sliding groove 12 are arranged on the upper part of the sealing plate 10, when the detection paper is not used, the rotating column 13 is rotated, the rotating column 13 slides in the sliding groove 12, the sealing plate 10 is driven to slide in the sliding groove 12, the accommodating openings 11 avoid the observation ports 9, a plurality of observation ports 9 are closed, and the detection paper card 3 in the sealing cover 2 is prevented from being polluted, when the urine needs to be detected, the position of the accommodating opening 11 is matched with the position of the observation port 9 by moving the rotating column 13, the protection, dustproof effect and moisture-proof effect of the detection paper card 3 are improved, and meanwhile, the operation is facilitated.

[0031] As a technical optimization scheme of the utility model, the lower part of the placing frame 4 is fixedly connected with a plug-in column 14, a plurality of plug-in grooves 15 adapted to the plug-in column 14 are arranged in the inner bottom of the detection box 1, when different detection paper cards 3 are needed to be used for detection, the placing frame 4 with the size adapted to the detection paper card 3 is installed in the detection box 1, the plug-in column 14 of the lower part of the placing frame 4 is plugged into the plug-in groove 15, so that the placing frame 4 can be installed, and the application range of the overall device is improved.

[0032] As a technical optimization scheme of the utility model, the side of the sealing cover 2 is fixedly provided with a plurality of elastic plates 16, one side of the elastic plate 16 is provided with a clamping boss 17, the side of the detection box 1 is provided with a clamping groove 18 adapted to the clamping boss 17, the opposite sides of the detection box 1 and the sealing cover 2 are both provided with an arc-shaped groove 19, the arc-shaped groove 19 is inlaid with a sealing ring 20 with elasticity, after the detection paper card 3 is installed, the sealing cover 2 is clamped on the upper part of the detection box 1, the clamping boss 17 on the side of the elastic plate 16 is clamped in the clamping groove 18, so that the sealing cover 2 and the detection box 1 can be connected, meanwhile, the detection box 1 and the sealing cover 2 extrude the sealing ring 20 located in the arc-shaped groove 19, the sealing property in the detection box 1 is improved, and the dustproof and moisture-proof effects of the overall device are improved.

[0033] Finally, it should be noted that: in the description of the utility model, it should be pointed out that the orientation or position relationship indicated by the terms "vertical", "upper", "lower", "horizontal" and the like is based on the orientation or position relationship shown in the drawings, and is only for the convenience of describing the utility model and simplifying the description, and does not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation on the utility model.

[0034] In the description of the utility model, it should also be pointed out that, unless otherwise explicitly specified and limited, the terms "arrangement", "installation", "connection", "connection" should be understood broadly, for example, it can be fixedly connected, or it can be detachably connected, or integrally connected, it can be mechanically connected, or it can be electrically connected, it can be directly connected, or indirectly connected through an intermediate medium, or it can be the communication between two elements. For ordinary skilled in the art, the specific meaning of the above terms in the utility model can be understood according to the specific circumstances.

[0035] The above is only the preferred embodiment of the utility model, and is not used to limit the utility model, although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacement for some technical features. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the utility model shall be included in the protection scope of the utility model.

Claims

1. A high-sensitivity stand-up dipstick urine test paper, comprising a detection box (1) and a sealing cover (2) connected to the upper part of the detection box (1), a plurality of detection paper cards (3) for detection are arranged in the detection box (1), characterized in that, The inner bottom of the detection box (1) is provided with a plurality of placement frames (4) for placing detection paper cards (3), the middle part of the sealing cover (2) is fixedly installed with a bearing column (5), the upper part of the bearing column (5) is provided with a sample adding groove (6), the side of the bearing column (5) in the detection box (1) is fixedly installed with a plurality of inclined flow tubes (7), the flow tubes (7) are in communication with the inner bottom of the sample adding groove (6) and the end away from the bearing column (5) is matched with the placement frame (4), the sample adding groove (6) is provided with a sealing ring (8) with elasticity for blocking the flow tube (7), and a plurality of observation openings (9) matched with the placement frame (4) are formed in the sealing cover (2).

2. The high sensitivity dipstick for detecting urine according to claim 1, wherein The end of the flow tube (7) close to the bearing column (5) is higher than the end of the flow tube (7) close to the placement frame (4) in horizontal height, the end of the flow tube (7) away from the bearing column (5) extends to a position above the middle part of the placement frame (4), and the upper side of the sealing ring (8) is fixedly connected with symmetrical pull blocks (21).

3. The high sensitivity dipstick for detecting urine according to claim 1, wherein The sealing cover (2) is provided with a rotatable sealing plate (10), a plurality of accommodation openings (11) matched with the observation openings (9) are formed in the sealing plate (10).

4. The high sensitivity dipstick for detecting urine according to claim 3, wherein The upper part of the sealing cover (2) is provided with a sliding groove (12), and the upper part of the sealing plate (10) is provided with a plurality of rotating columns (13) matched with the sliding groove (12).

5. The high sensitivity dipstick for detecting urine according to claim 1, wherein The lower part of the placement frame (4) is fixedly connected with a plug-in column (14), and the inner bottom of the detection box (1) is provided with a plurality of plug-in grooves (15) matched with the plug-in column (14).

6. The high sensitivity dipstick for detecting urine according to claim 1, wherein The side of the sealing cover (2) is fixedly installed with a plurality of elastic plates (16) with elasticity, one side of the elastic plate (16) is provided with a clamping boss (17), and the side of the detection box (1) is provided with a clamping groove (18) matched with the clamping boss (17).

7. The high sensitivity dipstick for detecting urine Listeria according to claim 6, characterized in that, The opposite sides of the detection box (1) and the sealing cover (2) are provided with arc-shaped grooves (19), and the arc-shaped grooves (19) are embedded with elastic sealing rings (20).

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