Bionic elastic elbow duodenum system

Abstract

The utility model relates to a bionic elastic elbow duodenum system which comprises a turntable, a stomach model, a duodenum model and a small intestine model, the rotating disc does circular motion around the circle center; the stomach model is arranged on the turntable, and the turntable drives the stomach model to rotate; the duodenum model comprises a hose and a spring, one end of the hose is connected with the output end of the stomach model, the other end of the hose is connected with the small intestine model, the spring is arranged on the hose in a sleeving mode, the connecting point of the hose and the stomach model is a movable point, the connecting point of the hose and the small intestine model is fixed, and the spring is arranged in an S shape. The bionic elastic elbow duodenum system is free of joints and color splicing, and the whole bionic elastic elbow duodenum system is more attractive; the silica gel material and the spring are more durable than plastics, and are not easy to break after being bent repeatedly; the inner wall is smooth, and chyme is not easy to block; the pipeline cannot be folded to cause blockage, and chyme flows smoothly.

Description

TECHNICAL FIELD

[0001] The utility model relates to bionic digestive system technical field, especially a kind of bionic elastic elbow pipe duodenum system. BACKGROUND

[0002] The digestive system of human body is very complex, simply speaking, food is mixed with gastric juice secreted by stomach and enzymatically hydrolyzed in stomach after being digested in oral cavity, and then is discharged into duodenum as small particles after being ground by stomach;Intestinal juice and bile are secreted in duodenum to digest chyme discharged by stomach, and then chyme is continuously digested and absorbed by jejunum and ileum.

[0003] Dynamic bionic gastrointestinal digestion system is an important tool for emerging food and drug research and development. In recent years, developing a more realistic and better in vitro digestion system has been a research hotspot. The bionic digestive system mainly consists of esophagus, stomach, duodenum, jejunum and ileum. The esophagus-stomach part of the bionic digestive system can deliver food bolus into the stomach and successfully discharge chyme into the duodenum after forming chyme in the stomach.

[0004] However, the system for further delivering chyme into jejunum after chyme enters duodenum still needs to be improved.

[0005] The existing bionic model has the following disadvantages:

[0006] 1) manual assembly is required, and installation is inconvenient: specifically, stainless steel joints and clamps are required for connection, and acid-base digestion products may damage the stainless steel joints during simulation of gastrointestinal digestion, and also contaminate the digestion products;

[0007] 2) when clamps are connected, liquid and gas leakage is easy to occur during experiment;

[0008] 3) the upper and lower materials are different and have color difference, and the appearance is poor;

[0009] 4) plastic pipe is not resistant to high temperature and cannot be sterilized at high temperature;

[0010] 5) plastic pipe is easy to break due to repeated bending, and has short service life;

[0011] 6) the inner wall of plastic pipe is not completely smooth, and chyme is easy to be embedded;

[0012] 7) plastic material is hard, easy to age and break, and the aged pipe is folded during movement, which blocks chyme;

[0013] 8) plastic pipe is directly purchased in market, and the source is unstable, and there are differences between batches, such as different sample residues caused by internal annular protrusions;

[0014] 9) unable to control the residence time of digestive products in the gray duodenum, large sample residue;

[0015] 10) gray plastic tube, no transparency, unable to observe internal phenomena. Invention content

[0016] To this end, the technical problem to be solved by the present application is to overcome the defects in the duodenum part of the existing bionic digestive system which has a stomach model similar to the real human body shape structure and a Z-shaped integrated small intestine model. The duodenum part of the existing technology is a stainless steel adapter nested at the connection between a silica gel tube and a gray plastic tube, which is fixed by a clamp. To avoid the blockage of digestive products in the duodenum during system operation, the gray duodenum tube is a hard plastic tube (with an annular thread inside) directly purchased from the market, which will fold and cause the passage to close during the model rotation process.

[0017] To solve the above technical problems, the present application provides a bionic elastic elbow pipe duodenum system, comprising: a turntable, a stomach model, a duodenum model and a small intestine model; the turntable makes a circular motion around the center; the stomach model is arranged on the turntable, and the turntable drives the stomach model to rotate; the duodenum model comprises a hose and a spring, one end of the hose is connected to the output end of the stomach model, and the other end of the hose is connected to the small intestine model, the spring is sleeved on the hose, the connection point of the hose and the stomach model is a movable point, the connection point of the hose and the small intestine model is fixed, and the spring is arranged in an "S" shape.

[0018] In an embodiment of the present application, the hose is a silica gel hose, and the hose is integrally formed.

[0019] In an embodiment of the present application, the hose comprises a first hose body and a second hose body, one end of the first hose body is connected to the stomach model, and the connection point of the first hose body and the stomach model is a movable point, one end of the second hose body is connected to the small intestine model, and the connection point of the second hose body and the small intestine model is fixed, the spring is nested outside the second hose body, and the connection point of the first hose body and the outer circumference of the turntable is fixed.

[0020] In an embodiment of the present application, one end of the first hose body and the second hose body is provided with a reducing joint, and the second hose body is connected to the reducing joint.

[0021] In an embodiment of the present application, one end of the second hose body connected to the small intestine model is provided with a rubber tube, the rubber tube is a hard silica gel tube, and the rubber tube and the second hose body are fixed by glue.

[0022] In an embodiment of the utility model, the outer circumference of one end of the rubber pipe close to the second hose body is equipped with an annular boss, the outer diameter of the annular boss is greater than the diameter of the spring, and the annular boss is used for limiting the spring from coming out by abutting against the spring.

[0023] In an embodiment of the utility model, the inner diameter of the first hose body is 30mm, the wall thickness of the first hose body is 5mm, and the length of the first hose body is 200mm.

[0024] In an embodiment of the utility model, the inner diameter of the second hose body is 20mm, the wall thickness of the second hose body is 5mm, and the length of the second hose body is 850mm.

[0025] In an embodiment of the utility model, the inner diameter of the spring is 800mm, and the length of the spring is 800mm.

[0026] In an embodiment of the utility model, the length of the reducing joint is 100mm.

[0027] The above technical scheme of the utility model has the following beneficial effects compared with the prior art:

[0028] 1. Integrated molding during model making, no need for splicing, easy to install, and can avoid liquid and gas leakage;

[0029] 2. No other impurities are introduced into the digestion product, ensuring that the experimental product is not polluted and improving experimental accuracy;

[0030] 3. No joint and color splicing, the whole is more beautiful;

[0031] 4. Compared with plastic, silicone material is more durable, and is not easy to break when repeatedly bent;

[0032] 5. Can be high-temperature sterilized, used for sterile experiments, and more suitable;

[0033] 6. Helps to standardize model making and improve experimental repeatability;

[0034] 7. Smooth inner wall, not easy to embed chyme;

[0035] 8. The pipeline will not be folded to cause occlusion, and chyme flows smoothly;

[0036] 9. The white silicone model has certain visibility, and whether the chyme passes through can be observed;

[0037] 10. More resistant to high temperature, easy to clean and dry. BRIEF DESCRIPTION OF DRAWINGS

[0038] In order to make the content of the utility model more easily be clearly understood, the following according to the specific embodiment of the utility model and combining with the drawings, the utility model is further explained in detail, wherein

[0039] Figure 1 It is the whole structure schematic view of bionic elastic curved pipe duodenum system in the preferred embodiment of the utility model;

[0040] Figure 2 It is the structure schematic view of duodenum model in the preferred embodiment of the utility model;

[0041] Figure 3 It is the structure schematic view of soft pipe in the preferred embodiment of the utility model;

[0042] Figure 4 It is the structure schematic view of spring in the preferred embodiment of the utility model.

[0043] Description of the drawing of the specification: turntable 1, stomach model 2, duodenum model 3, soft pipe 31, first soft pipe body 311, second soft pipe body 312, reducing joint 313, spring 32, small intestine model 4, rubber pipe 5, annular boss 51. Specific implementation

[0044] The utility model is further explained in combination with the drawings and specific embodiments, so that the person skilled in the art can better understand the utility model and can be implemented, but the embodiment is not as the limitation of the utility model.

[0045] Refer to Figures 1-4 The bionic elastic curved pipe duodenum system of the utility model, including: turntable 1, stomach model 2, duodenum model 3 and small intestine model 4 several parts;The turntable 1 makes the circumferential motion around the center;The stomach model 2 is arranged on the turntable 1, and the turntable 1 drives the stomach model 2 to rotate;The duodenum model 3 includes soft pipe 31 and spring 32, one end of the soft pipe 31 is connected with the output end of the stomach model 2, and the other end of the soft pipe 31 is connected with the small intestine model 4, the spring 32 is sleeved on the soft pipe 31, the connecting point of the soft pipe 31 and the stomach model 2 is the moving point, the connecting point of the soft pipe 31 and the small intestine model 4 is fixed, and the spring 32 is arranged in the form of "S".

[0046] This model is suitable for dynamic human gastrointestinal digestion equipment and is an important part of the whole simulation digestion system.The stomach model 2 is connected to the upper part, receives chyme, gastric juice and intestinal juice after digestion in the stomach and carries out digestion in the model;The small intestine model 4 is connected to the lower part, and the chyme after a period of digestion is discharged into the small intestine model 4.Therefore, this model is a very important digestion place and a channel connecting the upper and lower parts.

[0047] Specifically, the hose 31 is a white silica gel hose, and the hose 31 is integrally formed.

[0048] Referring to Figure 3 As shown in the drawings, the hose 31 includes two parts of a first hose body 311 and a second hose body 312, the first hose body 311 and the second hose body 312 are connected together to be an elongated tubular shape, one end of the first hose body 311 is connected with the stomach model 2, and the connection point of the first hose body 311 and the stomach model 2 is a movable point, one end of the second hose body 312 is connected with the small intestine model 4, and the connection point of the second hose body 312 and the small intestine model 4 is fixed, the spring 32 is nested outside the second hose body 312, and the connection point of the first hose body 311 and the outer circumference of the turntable 1 is fixed. The specific fixing structure of the hose 31 is that the connection point of the first hose body 311 and the stomach model 2, i.e. Figure 1 Point A in the middle can move with the turntable 1, the connection point of the first hose body 311 and the outer circumference of the turntable 1, i.e. Figure 1 Point B in the middle is a relatively fixed point (B point is relatively fixed with the turntable 1, but B point rotates with the turntable 1), and the connection point of the second hose body 312 and the small intestine model 4, i.e. Figure 1 Point C in the middle is also fixed. The stomach model 2 and the first hose body 311 will rotate with the turntable 1, and C point is fixed, so when the turntable 1 rotates, it will cause the duodenum model 3 to be folded, and the spring 32 can effectively avoid the folding problem of the duodenum model 3.

[0049] In the above structure, one end of the first hose body 311 and the second hose body 312 is provided with a reducing joint 313, and the second hose body 312 is connected with the reducing joint 313. The first hose body 311 and the second hose body 312 are both circular tubes, and the length of the first hose body 311 is less than the length of the second hose body 312, and the diameter of the first hose body 311 is greater than the diameter of the second hose body 312, so the reducing joint 313 is tapered, one end of the reducing joint 313 connected with the first hose body 311 has a larger diameter, and one end of the reducing joint 313 connected with the second hose body 312 has a smaller diameter, so that the diameter of the reducing joint 313 gradually decreases from the first hose body 311 to the second hose body 312.

[0050] In addition, one end of the second hose body 312 connected with the small intestine model 4 is provided with a rubber tube 5, the rubber tube 5 is a hard silica gel tube, and the rubber tube 5 is fixedly connected with the second hose body 312 by glue. An annular boss 51 is arranged on the outer circumference of one end of the rubber tube 5 close to the second hose body 312, the outer diameter of the annular boss 51 is greater than the diameter of the spring 32, and the annular boss 51 abuts against the spring 32 to limit the spring 32 from coming out.

[0051] The manufacturing steps of the above-mentioned hose 31 are as follows:

[0052] During manufacturing, firstly, silica gel is prepared, and after being mixed thoroughly, vacuum is drawn to remove the air bubbles in the silica gel, and then the silica gel is poured into the assembled mold, and after being cooled for 7-10 hours, the silica gel is taken out, trimmed simply, and then the spring 32 is sleeved on the second hose body 312, and a section of 20*5*70mm rubber tube 5 is inserted into the tail end of the second hose body 312, and the inserted part is fixed by using glue. The length of the inserted part of the rubber tube 5 into the second hose body 312 is 20mm, and the exposed part is 50mm. In this way, the spring 32 cannot fall out, and it is convenient to connect with the small intestine model 4 in the rear section.

[0053] Specifically, the sizes of the first hose body 311, the second hose body 312 and the spring 32 are as follows: the inner diameter of the first hose body 311 is 30mm, the wall thickness of the first hose body 311 is 5mm, and the length of the first hose body 311 is 200mm. The inner diameter of the second hose body 312 is 20mm, the wall thickness of the second hose body 312 is 5mm, and the length of the second hose body 312 is 850mm. The inner diameter of the spring 32 is 1.5mm, and the length of the spring 32 is 800mm. The diameter of the cross section of the steel wire used in the spring 32 is 1.5mm, and the thread tightness of the spring 32 is about 1cm.

[0054] In addition, the length of the reducing joint 313 is 100mm.

[0055] The use principle of the bionic elastic elbow pipe duodenum system of the utility model is as follows:

[0056] When the duodenum model 3 is installed on the whole system, firstly, the upper part of the duodenum model 3 is passed through the duodenum valve of the whole system from bottom to top, sequentially passes through the duodenum extrusion plate of the whole system, and is connected with the stomach model 2. The spring 32 is clamped by using the clamp at the reducing joint 313, the lower part of the duodenum model 3 is clamped into the clamping groove, the spring 32 is in S shape as a whole, and the duodenum model 3 is connected with the small intestine model 4.

[0057] After the food sample enters the duodenum model 3, the food sample is mixed and digested with the intestinal fluid simulation liquid at the duodenum extrusion plate, and then the duodenum valve is opened, the food sample flows into the second hose body 312 part with the spring elbow pipe, and can slowly flow into the small intestine model 4 along the pipeline path.

[0058] Obviously, the above embodiments are only examples for clearly illustrating the present application and are not intended to limit the present application. Based on the above description, other different forms of changes or variations can be made by those skilled in the art. Here, all the embodiments are not required to be enumerated. The obvious changes or variations derived therefrom are still within the protection scope of the present application.

Claims

1. A biomimetic elastic curved duodenal system, characterized in that, include: Rotary disc, stomach model, duodenal model, and small intestine model; A turntable that revolves around a center point; A stomach model is mounted on a turntable, which drives the stomach model to rotate. The duodenal model includes a flexible tube and a spring. One end of the flexible tube is connected to the output end of the stomach model, and the other end of the flexible tube is connected to the small intestine model. The spring is sleeved on the flexible tube. The connection point between the flexible tube and the stomach model is a movable point, while the connection point between the flexible tube and the small intestine model is fixed. The spring is arranged in an "S" shape.

2. The biomimetic elastic curved duodenal system according to claim 1, characterized in that: The hose is a silicone hose, and the hose is integrally molded.

3. The biomimetic elastic curved duodenal system according to claim 2, characterized in that: The hose includes a first hose body and a second hose body. One end of the first hose body is connected to the stomach model, and the connection point between the first hose body and the stomach model is a movable point. One end of the second hose body is connected to the small intestine model, and the connection point between the second hose body and the small intestine model is fixed. The spring is nested outside the second hose body, and the connection point between the first hose body and the outer circumference of the turntable is fixed.

4. The biomimetic elastic curved duodenal system according to claim 3, characterized in that: The first hose body is connected to the second hose body at one end with a reducing connector, and the second hose body is connected to the reducing connector.

5. The biomimetic elastic curved duodenal system according to claim 4, characterized in that: The second flexible tube body is connected to the small intestine model at one end with a rubber tube, which is a rigid silicone tube, and the rubber tube is bonded and fixed to the second flexible tube body with glue.

6. The biomimetic elastic curved duodenal system according to claim 5, characterized in that: The outer circumference of the hose near the second hose body is provided with an annular boss. The outer diameter of the annular boss is larger than the diameter of the spring. The annular boss abuts against the spring to prevent the spring from disengaging.

7. The biomimetic elastic curved duodenal system according to claim 3, characterized in that: The inner diameter of the first hose body is 30mm, the wall thickness of the first hose body is 5mm, and the length of the first hose body is 200mm.

8. The biomimetic elastic curved duodenal system according to claim 3 or 7, characterized in that: The inner diameter of the second hose body is 20mm, the wall thickness of the second hose body is 5mm, and the length of the second hose body is 850mm.

9. The biomimetic elastic curved duodenal system according to claim 8, characterized in that: The inner diameter of the spring is [value missing], and the length of the spring is 800 mm.

10. The biomimetic elastic curved duodenal system according to claim 4, characterized in that: The length of the reducing joint is 100mm.

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