Polypeptide cracking circulating cooling device

By employing a combination of heat dissipation fins and a fan in the peptide lysis circulating cooling device, along with a preheating mechanism, the problem of heat dissipation being affected by ambient temperature was solved, achieving stable temperature control in high-temperature environments.

CN224136184UActive Publication Date: 2026-04-17上海昱郦生物科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
上海昱郦生物科技有限公司
Filing Date
2025-05-15
Publication Date
2026-04-17

AI Technical Summary

Technical Problem

Ambient temperature affects the heat dissipation effect of the cooling device, leading to inaccurate temperature control, especially in hot summer when the heat dissipation effect is reduced.

Method used

It adopts a combination structure of heat dissipation fins and fan, and adjusts the fan speed through bimetallic coiled springs to improve air circulation speed; it uses a preheating mechanism to heat hot air into water to preheat the solvent in the solvent pipe, thereby enhancing the cooling effect.

Benefits of technology

To improve the cooling efficiency of the cooling medium in high-temperature environments, ensure the stability of the internal temperature control of the reactor, and avoid the influence of ambient temperature on the cooling effect.

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Abstract

The utility model relates to the technical field of cooling, in particular to a circulating cooling device for polypeptide cracking. According to the technical scheme, the heat exchange mechanism comprises a fixed frame, heat dissipation fins are fixedly installed in the center of the fixed frame, a fan is rotationally connected to the back of the fixed frame, a bimetallic coil spring piece is fixedly installed on the side of the fixed frame, the end of the bimetallic coil spring piece is bent, and a gap exists between the end of the bimetallic coil spring piece and the fixed frame; and the top of the fixed frame is rotationally connected with a knob electrically connected with the fan. When the environment temperature is high, the cooling effect of the cooling fins on the cooling medium is reduced, the high temperature of the cooling medium can cause that the internal temperature of the reaction kettle cannot be controlled, and at the moment, the cold-heat exchange efficiency of air and the cooling medium is accelerated by increasing the rotating speed of the fan and increasing the air circulation speed at the cooling fins; the environment temperature is prevented from affecting the heat dissipation effect of the cooling device.
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Description

Technical Field

[0001] This utility model relates to the field of cooling technology, and in particular to a polypeptide lysis circulating cooling device. Background Technology

[0002] During peptide cleavage, heat is generated. The circulating cooling device mainly consists of a cooling unit, a circulation unit, a temperature control unit, and a cleavage reaction vessel. The heat generated by the cleavage reaction is absorbed by the cooling medium (such as cold water or coolant) in the cooling pipes of the cooling unit. The circulation pump drives the cooling medium to circulate in the pipes to achieve continuous heat transfer, and the temperature control unit monitors the reaction temperature in real time.

[0003] Temperature can be precisely regulated by controlling the flow rate of the cooling medium or the operation of the refrigeration equipment, so that the pyrolysis reaction can proceed under suitable temperature conditions, ensuring the stability of the reaction and the quality of the products.

[0004] External environmental factors (such as ambient temperature) can interfere with the accuracy of temperature control. In the hot summer, the high ambient temperature can affect the heat dissipation effect of the cooling device, leading to deviations in temperature control. Utility Model Content

[0005] The purpose of this invention is to address the problem in the background art where ambient temperature affects the heat dissipation effect of cooling devices, and to propose a polypeptide lysis circulating cooling device.

[0006] The technical solution of this utility model is as follows: a polypeptide lysis circulating cooling device, including a reaction vessel, a solvent pipe fixedly installed on the top of the reaction vessel, and a circulating cooling pipe connected to the side of the reaction vessel;

[0007] A heat exchange mechanism includes a fixed frame, a heat dissipation fin fixedly installed at the center of the fixed frame, a fan rotatably connected to the back of the fixed frame, a bimetallic coiled spring fixedly installed on the side of the fixed frame, the end of the bimetallic coiled spring being bent and having a gap with the fixed frame, a knob electrically connected to the fan being rotatably connected to the top of the fixed frame, and a transmission intermediate component being provided between the bimetallic coiled spring and the knob.

[0008] A preheating mechanism extending to the outer wall of the solvent pipe is provided on the front side of the fixed frame.

[0009] Optionally, the transmission intermediate component includes a square frame and a toothed plate. The bottom of the toothed plate is slidably connected to a fixed frame, the side of the toothed plate is engaged with a knob, the other side of the toothed plate is fixedly connected to the square frame, and the end of the bimetallic coil spring extends to the center of the square frame.

[0010] Optionally, the knob has multiple teeth on its outer arc surface, and the multiple teeth are distributed in a ring at equal angles along the outer arc surface of the knob. The knob is connected to the toothed plate through the teeth.

[0011] Optionally, the end of the bimetallic coil spring adopts a U-shaped structure, and a roller is rotatably connected inside the opening of the bimetallic coil spring, the roller sliding up and down along the frame.

[0012] Optionally, the preheating mechanism includes a heat-concentrating cylinder, one end of which is fixedly connected to a fixed frame, a water tank is fixedly installed on the outer wall of the solvent pipe, the water tank is filled with heat-exchange water, and a hot air pipe for heating water is fixedly installed at the other end of the heat-concentrating cylinder.

[0013] Optionally, a heat exchange tube is fixedly installed at the end of the hot air pipe. The heat exchange tube is located inside the water tank and has a spiral structure. The other end of the heat exchange tube extends out from inside the water tank.

[0014] Optionally, the solvent pipe passes through the center of the heat exchange tube and absorbs heat from the water inside the water tank.

[0015] Optionally, a circulating pump is fixedly installed on the outer wall of the circulating cooling pipe and on top of the fixed frame, and the interior of the reactor is provided with a jacket, with the two ends of the circulating cooling pipe respectively connected to the upper and lower ends of the jacket.

[0016] Compared with the prior art, the present invention has the following beneficial technical effects:

[0017] When the ambient temperature is high, the cooling effect of the heat sink fins on the cooling medium decreases, and the high temperature of the cooling medium will cause the internal temperature of the reactor to become uncontrollable. At this time, by increasing the fan speed, the airflow speed at the heat sink fins is increased, thereby accelerating the heat exchange efficiency between the air and the cooling medium and avoiding the impact of the ambient temperature on the heat dissipation effect of the cooling device.

[0018] Furthermore, a fan blows hot air from the heat sink fins into the heat collection cylinder, which then transfers the hot air to the water tank to heat the water inside. Finally, the water in the water tank is used to preheat the solvent added to the solvent pipe. Attached Figure Description

[0019] Figure 1 A schematic diagram of the overall structure of this utility model is provided;

[0020] Figure 2 This is a schematic diagram of the heat dissipation fin structure of this utility model;

[0021] Figure 3 This is a schematic diagram of the bimetallic coiled spring structure of this utility model;

[0022] Figure 4 for Figure 3 Enlarged schematic diagram of the box structure in part A;

[0023] Figure 5 This is a top sectional view of the water tank structure of this utility model.

[0024] Reference numerals: 1. Reactor; 2. Solvent pipe; 3. Circulating cooling pipe; 4. Circulating pump; 5. Heat exchange mechanism; 51. Fixed frame; 52. Heat dissipation fins; 53. Fan; 54. Bimetallic coiled spring; 55. Roller; 56. Square frame; 57. Toothed plate; 58. Knob; 6. Preheating mechanism; 61. Heat collection cylinder; 62. Hot air pipe; 63. Heat exchange pipe; 64. Water tank. Detailed Implementation

[0025] The technical solution of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are some embodiments of this utility model, but not all embodiments.

[0026] The components of the present invention embodiments described and shown in the accompanying drawings can typically be arranged and designed in a variety of different configurations. Therefore, the following detailed description of the embodiments of the present invention provided in the drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention.

[0027] Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0028] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0029] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0030] Example 1

[0031] This embodiment proposes a polypeptide lysis circulating cooling device, such as... Figure 1 As shown, the reactor includes a reactor 1, a solvent pipe 2 is fixedly installed on the top of the reactor 1, a circulating cooling pipe 3 is connected to the side of the reactor 1, a circulating pump 4 is fixedly installed on the outer wall of the circulating cooling pipe 3 and on the top of the fixed frame 51, and a jacket is provided inside the reactor 1, with the two ends of the circulating cooling pipe 3 connected to the upper and lower ends of the jacket respectively.

[0032] The cooling medium is pumped by the circulating pump 4, thereby circulating the cooling medium in the circulating cooling pipe 3 and the jacket to cool the internal temperature of the reactor 1.

[0033] like Figure 2 As shown, a heat exchange mechanism 5 is provided on the side of the reactor 1. The heat exchange mechanism 5 includes a fixed frame 51. A heat dissipation fin 52 is fixedly installed at the center of the fixed frame 51. A fan 53 is rotatably connected to the back of the fixed frame 51. The fan 53 rotates to accelerate the airflow at the heat dissipation fin 52, thereby reducing the temperature of the cooling medium.

[0034] like Figure 3 and Figure 4 As shown, a bimetallic coil spring 54 is fixedly installed on the side of the fixed frame 51. The end of the bimetallic coil spring 54 is bent and there is a gap between it and the fixed frame 51. A knob 58 electrically connected to the fan 53 is rotatably connected to the top of the fixed frame 51. A transmission intermediate component is provided between the bimetallic coil spring 54 and the knob 58. The transmission intermediate component includes a square frame 56 and a toothed plate 57. The bottom of the toothed plate 57 is slidably connected to the fixed frame 51. Multiple teeth are provided on the outer arc surface of the knob 58. The multiple teeth are distributed in a ring at equal angles along the outer arc surface of the knob 58. The knob 58 is connected to the toothed plate 57 through the teeth. The other side of the toothed plate 57 is fixedly connected to the square frame 56. The end of the bimetallic coil spring 54 extends to the center of the square frame 56.

[0035] The bimetallic coiled spring 54 contracts under the influence of ambient temperature, causing the bent portion at its end to shift. This movement of the spring 54 drives the frame 56, which in turn rotates the knob 58 via the toothed plate 57, thus changing the rotational speed of the fan 53. In high ambient temperatures, the bimetallic coiled spring 54 expands, causing its bent end to rotate counter-clockwise. This moves the toothed plate 57 to the left and rotates the knob 58 clockwise, increasing the fan 53's speed. In low ambient temperatures, the opposite occurs. The knob 58 provides stepless adjustment of the fan 53's speed, and its rotational resistance is low to reduce friction.

[0036] The end of the bimetallic coil spring 54 has a U-shaped structure, and a roller 55 is rotatably connected inside the opening of the bimetallic coil spring 54. The roller 55 slides up and down along the frame 56. The roller 55 and the frame 56 cooperate to prevent the bimetallic coil spring 54 from getting stuck during rotation.

[0037] In this embodiment, when the ambient temperature is high, the cooling effect of the heat dissipation fins 52 on the cooling medium is reduced. If the temperature of the cooling medium is high, the internal temperature of the reactor 1 will be uncontrollable. At this time, by increasing the speed of the fan 53, the airflow speed at the heat dissipation fins 52 is increased, so as to accelerate the heat exchange efficiency between the air and the cooling medium and avoid the ambient temperature from affecting the heat dissipation effect of the cooling device.

[0038] Example 2

[0039] Based on Example 1, this example proposes a polypeptide lysis circulating cooling device, such as... Figure 5 As shown, a preheating mechanism 6 extending to the outer wall of the solvent pipe 2 is provided on the front side of the fixed frame 51. The preheating mechanism 6 includes a heat-concentrating cylinder 61. The end of the heat-concentrating cylinder 61 is fixedly connected to the fixed frame 51. A water tank 64 is fixedly installed on the outer wall of the solvent pipe 2. The water tank 64 is filled with heat-exchange water. A hot air pipe 62 for heating water is fixedly installed at the other end of the heat-concentrating cylinder 61.

[0040] Solvent pipe 2 passes through the axis of heat exchange tube 63. Solvent pipe 2 absorbs heat from the water inside water tank 64. The hot air from the heat dissipation fins 52 is blown into heat collection cylinder 61 by fan 53. Heat collection cylinder 61 heats the water inside water tank 64. Finally, the water in water tank 64 is used to preheat the solvent added to solvent pipe 2.

[0041] A heat exchange tube 63 is fixedly installed at the end of the hot air pipe 62. The heat exchange tube 63 is located inside the water tank 64 and has a spiral structure. The other end of the heat exchange tube 63 extends out from inside the water tank 64. The spiral heat exchange tube 63 extends the residence time of the hot air inside the water tank 64.

[0042] In this embodiment, the hot air at the heat dissipation fins 52 is blown into the heat collection cylinder 61 by the fan 53. The heat collection cylinder 61 transfers the hot air to the water tank 64 to heat the water inside the water tank 64. Finally, the water in the water tank 64 is used to preheat the solvent added at the solvent pipe 2.

[0043] The above specific embodiments are merely several optional embodiments of this utility model. Based on the technical solution of this utility model and the relevant teachings of the above embodiments, those skilled in the art can make various alternative improvements and combinations to the above specific embodiments.

Claims

1. A polypeptide cleavage circulating cooling device, comprising: A reaction vessel (1), wherein a solvent pipe (2) is fixedly installed on the top of the reaction vessel (1), and a circulating cooling pipe (3) is connected to the side of the reaction vessel (1), characterized in that: The heat exchange mechanism (5) includes a fixed frame (51), a heat dissipation fin (52) is fixedly installed at the center of the fixed frame (51), a fan (53) is rotatably connected to the back of the fixed frame (51), a bimetallic coil spring (54) is fixedly installed on the side of the fixed frame (51), the end of the bimetallic coil spring (54) is bent and there is a gap between it and the fixed frame (51), a knob (58) electrically connected to the fan (53) is rotatably connected to the top of the fixed frame (51), and a transmission intermediate is provided between the bimetallic coil spring (54) and the knob (58); The front side of the fixed frame (51) is provided with a preheating mechanism (6) that extends to the outer wall of the solvent pipe (2).

2. The polypeptide cleavage circulating cooling device according to claim 1, characterized in that: The transmission intermediate component includes a square frame (56) and a toothed plate (57). The bottom of the toothed plate (57) is slidably connected to the fixed frame (51), the side of the toothed plate (57) is engaged with the knob (58), the other side of the toothed plate (57) is fixedly connected to the square frame (56), and the end of the bimetallic coil spring (54) extends to the center of the square frame (56).

3. The polypeptide cleavage circulating cooling device according to claim 2, characterized in that: The knob (58) has multiple teeth on its outer arc surface. The multiple teeth are distributed in a ring at equal angles along the outer arc surface of the knob (58). The knob (58) is connected to the toothed plate (57) by meshing through the teeth.

4. The polypeptide cleavage circulating cooling device according to claim 3, characterized in that: The end of the bimetallic coil spring (54) adopts a U-shaped structure, and a roller (55) is rotatably connected inside the opening of the bimetallic coil spring (54). The roller (55) slides up and down along the frame (56).

5. A polypeptide cleavage circulating cooling device according to claim 4, wherein: The preheating mechanism (6) includes a heat-concentrating cylinder (61), the end of which is fixedly connected to a fixed frame (51). A water tank (64) is fixedly installed on the outer wall of the solvent pipe (2), and the water tank (64) is filled with heat-exchanging water. A hot air pipe (62) for heating water is fixedly installed at the other end of the heat-concentrating cylinder (61).

6. A polypeptide cleavage circulating cooling device according to claim 5, wherein: A heat exchange tube (63) is fixedly installed at the end of the hot air pipe (62). The heat exchange tube (63) is located inside the water tank (64). The heat exchange tube (63) adopts a spiral structure, and the other end of the heat exchange tube (63) extends out from inside the water tank (64).

7. The polypeptide lysis circulating cooling device according to claim 6, characterized in that: The solvent pipe (2) passes through the center of the heat exchange tube (63) and absorbs heat from the water inside the water tank (64).

8. The polypeptide cleavage circulating cooling device of claim 1, wherein: A circulating pump (4) is fixedly installed on the outer wall of the circulating cooling pipe (3) and on the top of the fixed frame (51). The reactor (1) has an internal jacket, and the two ends of the circulating cooling pipe (3) are respectively connected to the upper and lower ends of the jacket.