Liquid phase front-end full-automatic sample introduction frame converter

Abstract

The utility model belongs to the field of liquid phase front-end equipment, in particular relates to a liquid phase front-end full-automatic sample introduction frame converter, and aims to solve the problems that a kit containing a sample is manually placed in an instrument for detection during sample introduction of an existing liquid chromatograph, and the kit is taken out after the detection, so that the operation is troublesome, the detection time is short and the like. In order to solve the problem that the labor force of personnel is increased under the condition that the workload is relatively large, the utility model provides the following scheme that the device comprises a detection cabinet and a placement cabinet, one side of the placement cabinet is fixedly connected with one side of the detection cabinet, and through holes are formed in the sides, close to each other, of the placement cabinet and the detection cabinet and are communicated with each other; by means of the clamping mechanism, the conveying mechanism, the adjusting mechanism and the electric push rod, a worker does not need to take and place the kits back and forth, the kits to be detected and the detected kits are automatically exchanged, more convenience is achieved, and labor force is saved.

Description

Technical Field

[0001] This utility model relates to the field of liquid phase front-end equipment technology, and in particular to a fully automatic liquid phase front-end sample feeder converter. Background Technology

[0002] Liquid chromatography is a chromatographic technique based on liquid as the medium. It separates mixtures by utilizing the difference in the distribution ratio between liquid and solid or between two immiscible liquids.

[0003] Existing liquid chromatographs have the following shortcomings in use:

[0004] When injecting samples into a liquid chromatograph, the reagent kit containing the sample is placed into the instrument manually for detection, and then removed after detection. This is quite troublesome and increases the workload for personnel, especially when the workload is large. Utility Model Content

[0005] The purpose of this invention is to solve the problem that in the existing technology, when injecting samples into a liquid chromatograph, the reagent kit containing the sample is placed into the instrument for detection, and then removed after detection, which is cumbersome and increases the labor burden when the workload is large. Therefore, a fully automatic sample holder changer for the front end of a liquid chromatograph is proposed.

[0006] To achieve the above objectives, the present invention adopts the following technical solution:

[0007] A fully automated liquid chromatography front-end sample holder changer includes a detection cabinet and a placement cabinet. One side of the placement cabinet is fixedly connected to one side of the detection cabinet. Both the placement cabinet and the detection cabinet have through holes on their adjacent sides and are connected to each other. Multiple placement plates for placing reagent kits are fixedly installed on the inner walls of both sides of the placement cabinet. A notch is opened on one side of the detection cabinet. A sliding groove is opened on the inner wall of the bottom of the detection cabinet. A sliding strip is slidably connected to the inner wall of the sliding groove. A movable plate for placing reagent kits is fixedly installed on the top of the sliding strip. A pull plate is fixedly installed on one side of the top of the movable plate. A door is installed on one side of the placement cabinet via a hinge.

[0008] A clamping mechanism is installed inside the storage cabinet to clamp the reagent kit;

[0009] The conveying mechanism is installed inside the placement cabinet and the testing cabinet and is used to move the clamping mechanism left and right.

[0010] An adjustment mechanism, located inside the placement cabinet, is used to adjust the clamping mechanism vertically to facilitate clamping the reagent kits on the placement plate.

[0011] Preferably, the clamping mechanism includes a second concave plate, a second motor, a bidirectional lead screw, and two clamping plates. One side of the second motor is fixedly connected to one side of the second concave plate. The two ends of the bidirectional lead screw are rotatably connected to the inner walls of both sides of the second concave plate, respectively. The output end of the second motor passes through one side of the second concave plate and is fixedly connected to one end of the bidirectional lead screw. One side of each clamping plate is slidably connected to the inner wall of one side of the second concave plate. A first lead screw nut is embedded in one side of each clamping plate, and the first lead screw nut is threadedly connected to the bidirectional lead screw.

[0012] Preferably, the conveying mechanism includes a first concave plate, a first motor, a lead screw, and a moving block. One side of the first concave plate is slidably connected to the inner wall of one side of the testing cabinet and the placement cabinet. One side of the first motor is fixedly connected to one side of the first concave plate. One end of the lead screw is fixedly connected to the output end of the first motor, and the other end of the lead screw is rotatably connected to the inner wall of one side of the first concave plate. A second lead screw nut is embedded in one side of the moving block, and the second lead screw nut is threadedly connected to the lead screw.

[0013] Preferably, the adjustment mechanism includes a threaded rod, a third motor, and a connecting block. The bottom end of the threaded rod is rotatably connected to the bottom inner wall of the placement cabinet, the top of the third motor is fixedly connected to the top inner wall of the placement cabinet, the top end of the threaded rod is fixedly connected to the output end of the third motor, the connecting block has a threaded hole, the threaded rod is threadedly connected to the threaded hole, and one side of the first concave plate on one side of the connecting block is fixedly connected.

[0014] Preferably, an electric push rod for driving the clamping plate to move back and forth is fixedly provided on one side of the moving block, and the telescopic part of the electric push rod is fixedly connected to one side of the second concave plate.

[0015] Preferably, the top of the placement plate is fixedly provided with two limiting strips for limiting the two sides of the reagent kit.

[0016] Preferably, rubber pads for improving the clamping effect are fixedly provided on the side of the two clamping plates that are close to each other.

[0017] In this application, during use, firstly, open the door on one side of the placement cabinet, place the reagent kit on the placement plate between the two limit strips, and then close the door. Next, start the third motor to drive the threaded rod to rotate. Since the threaded hole on the connecting block is threadedly connected to the threaded rod, the connecting block will drive the first concave plate to move up and down. As the first concave plate moves up and down, the conveying mechanism and the clamping mechanism also move to the appropriate height so that the clamping mechanism can clamp the reagent kit at the designated position. After the conveying mechanism moves the clamping mechanism to the designated position, start the electric push rod. The extension and retraction of the electric push rod's telescopic part drives the movement of the clamping mechanism, so that the clamping plate is located at the reagent kit position. Then, start the second motor to drive the bidirectional lead screw to rotate. Since the first lead screw nut on the clamping plate is threadedly connected to the bidirectional lead screw, the two clamping plates will move towards each other, clamping the reagent kit, thus clamping the reagent kit. After clamping, the electric push rod's telescopic part retracts to the initial position, so that the clamping plate and the reagent kit are located in the through hole of the testing cabinet and the placement cabinet (where the length of the clamping plate is measured by a ruler). The device (which can hold the reagent kit) then starts the first motor of the conveying mechanism, driving the lead screw to rotate. Since the second lead screw nut on the moving block is threadedly connected to the lead screw, the moving block will drive the clamping mechanism and the reagent kit to move together towards the testing cabinet. After the reagent kit is conveyed into the testing cabinet, the third motor lowers the reagent kit to the moving plate, and the second motor releases the fixation of the reagent kit. The moving plate can hold three reagent kits. After the reagent kits in the testing cabinet have been tested, the device returns to the initial position through the electric push rod, clamping mechanism, conveying mechanism, and adjusting mechanism, and then clamps the untested reagent kits. The clamping mechanism, conveying mechanism, adjusting mechanism, and electric push rod eliminate the need for personnel to pick up and put down the reagent kits, automatically exchanging the reagent kits to be tested and those that have been tested, which is more convenient and saves labor. It should be noted that the first motor, second motor, third motor, and electric push rod need to be controlled by an external controller and powered by an external power supply before use. The first motor, second motor, and third motor can all be stepper motors, which can rotate in both directions.

[0018] In this utility model, the liquid phase front-end fully automatic sample feeder changer uses a clamping mechanism. The second motor is started and drives the bidirectional lead screw to rotate. Since the first lead screw nut on the clamping plate is threadedly connected to the bidirectional lead screw, the two clamping plates will move towards each other to clamp the reagent kit, thereby clamping the reagent kit.

[0019] In this utility model, the fully automatic liquid phase front-end sample feeder changer, through the conveying mechanism, drives the first motor of the conveying mechanism to rotate the lead screw. Since the second lead screw nut on the moving block is threadedly connected to the lead screw, the moving block will drive the clamping mechanism and the reagent kit to move together into the detection cabinet.

[0020] In this utility model, the fully automatic liquid phase front-end sample feeder changer starts the third motor through the adjustment mechanism, drives the threaded rod to rotate. Since the threaded hole on the connecting block is threadedly connected to the threaded rod, the connecting block will drive the first concave plate to move up and down. As the first concave plate moves up and down, the conveying mechanism and the clamping mechanism also move to a suitable height so that the clamping mechanism can clamp the reagent kit at the designated position.

[0021] In this invention, the clamping mechanism, conveying mechanism, adjusting mechanism, and electric push rod eliminate the need for personnel to repeatedly pick up and place the reagents. The reagents to be tested and the tested reagents are automatically exchanged, making it more convenient and saving labor. Attached Figure Description

[0022] Figure 1 This is a schematic diagram of the main structure of a fully automatic liquid phase front-end sample feeder converter proposed in this utility model;

[0023] Figure 2 This is a side view of the fully automatic liquid phase front-end sample feeder converter proposed in this utility model;

[0024] Figure 3 This is a schematic diagram of the structure of a fully automatic liquid phase front-end sample feeder converter in its uninstalled gate state, as proposed in this utility model.

[0025] Figure 4 This is a cross-sectional view of the placement cabinet of a fully automatic liquid phase front-end sample feeder converter proposed in this utility model;

[0026] Figure 5 This is a schematic diagram of the internal structure of the detection cabinet of a fully automatic liquid phase front-end sample feeder converter proposed in this utility model.

[0027] In the diagram: 1. Testing cabinet; 2. Placement cabinet; 3. Pull plate; 4. Door; 5. Placement plate; 6. Limiting strip; 7. Clamping plate; 8. First concave plate; 9. Moving block; 10. Two-way lead screw; 11. Electric push rod; 12. Second concave plate; 13. Lead screw; 14. Second motor; 15. Threaded rod; 16. Moving plate. Detailed Implementation

[0028] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.

[0029] Example 1

[0030] Reference Figure 1-5An automated liquid chromatography front-end sample feeder changer, used in the field of liquid chromatography front-end equipment, comprises: a detection cabinet 1, a placement cabinet 2, a clamping mechanism, a conveying mechanism, and an adjusting mechanism. The detection cabinet 1 and the placement cabinet 2 are fixedly connected on one side, and both sides have interconnected through holes. Multiple placement plates 5 for placing reagent kits are fixedly installed on the inner walls of both sides of the placement cabinet 2. A notch is provided on one side of the detection cabinet 1 to facilitate the entry and exit of reagent kits. A sliding groove is provided on the bottom inner wall of the detection cabinet 1, and a sliding strip is slidably connected within the groove. A movable plate 16 is fixedly installed on the top of the sliding strip for placing reagent kits. A pull plate 3 is fixedly installed on one side of the top of the movable plate 16 to facilitate manual movement of the movable plate 16 by the operator. A door 4 is hinged to one side of the placement cabinet 2 to facilitate the insertion and removal of reagent kits by the operator.

[0031] A clamping mechanism is installed inside the placement cabinet 2 to clamp the reagent kit. The clamping mechanism includes a second concave plate 12, a second motor 14, a bidirectional lead screw 10, and two clamping plates 7. One side of the second motor 14 is fixedly connected to one side of the second concave plate 12, and both ends of the bidirectional lead screw 10 are rotatably connected to the inner walls of both sides of the second concave plate 12. The output end of the second motor 14 passes through one side of the second concave plate 12 and is fixedly connected to one end of the bidirectional lead screw 10. One side of each clamping plate 7 is slidably connected to the inner wall of one side of the second concave plate 12, and a first lead screw nut is embedded in one side of each clamping plate 7, which is threadedly connected to the bidirectional lead screw 10. When the second motor 14 operates, it drives the bidirectional lead screw 10 to rotate, thereby causing the two clamping plates 7 to move towards or away from each other, thus clamping or releasing the reagent kit. Furthermore, rubber pads are fixedly installed on the sides of the two clamping plates 7 that are close to each other to improve the clamping effect and protect the reagent kit from damage.

[0032] A conveying mechanism is installed inside the placement cabinet 2 and the testing cabinet 1 to move the clamping mechanism left and right. The conveying mechanism includes a first concave plate 8, a first motor, a lead screw 13, and a moving block 9. One side of the first concave plate 8 is slidably connected to the inner wall of one side of the testing cabinet 1 and the placement cabinet 2, and one side of the first motor is fixedly connected to one side of the first concave plate 8. One end of the lead screw 13 is fixedly connected to the output end of the first motor, and the other end is rotatably connected to the inner wall of one side of the first concave plate 8. A second lead screw nut is embedded in one side of the moving block 9, and the second lead screw nut is threadedly connected to the lead screw 13. When the first motor operates, it drives the lead screw 13 to rotate, thereby causing the moving block 9 to move left and right on the first concave plate 8. An electric push rod 11 is also fixedly installed on one side of the moving block 9, and the telescopic part of the electric push rod 11 is fixedly connected to one side of the second concave plate 12. Therefore, when the moving block 9 moves, it drives the clamping mechanism and the reagent kit to move together. By adjusting the extension length of the electric push rod 11, the clamping mechanism can be moved back and forth, thereby adjusting the position of the reagent kit more precisely.

[0033] An adjustment mechanism is installed inside the placement cabinet 2 to adjust the clamping mechanism vertically, facilitating the clamping of reagent kits on the placement plate 5. The adjustment mechanism includes a threaded rod 15, a third motor, and a connecting block. The bottom end of the threaded rod 15 is rotatably connected to the bottom inner wall of the placement cabinet 2, the top of the third motor is fixedly connected to the top inner wall of the placement cabinet 2, and the top end of the threaded rod 15 is fixedly connected to the output end of the third motor. A threaded hole is provided on the connecting block, and the threaded rod 15 is threadedly connected to the threaded hole. One side of the connecting block is fixedly connected to one side of the first concave plate 8. Therefore, when the third motor operates, it drives the threaded rod 15 to rotate, causing the connecting block and the first concave plate 8 to move vertically together. This allows for vertical adjustment of the clamping mechanism, enabling the clamping of reagent kits at different heights.

[0034] This application is for the field of liquid phase front-end equipment, but can also be used in other fields applicable to this application.

[0035] Example 2

[0036] refer to Figure 1-5 An improvement based on Example 1:

[0037] Two limiting strips 6 are also fixedly installed on the top of each placement plate 5 to limit the sides of the reagent kit.

[0038] However, as is well known to those skilled in the art, the working principles and wiring methods of the first motor, the second motor 14, the third motor, and the electric push rod 11 are commonplace and belong to conventional methods or common knowledge. They will not be described in detail here. Those skilled in the art can make any selections according to their needs or convenience.

[0039] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.

Claims

1. A fully automatic liquid chromatography front-end sample feeder changer, characterized in that, The system includes a testing cabinet (1), a placement cabinet (2), a clamping mechanism, a conveying mechanism, and an adjusting mechanism. One side of the placement cabinet (2) is fixedly connected to one side of the testing cabinet (1). Both the placement cabinet (2) and the testing cabinet (1) have through holes on their adjacent sides, which are connected to each other. Multiple placement plates (5) for placing reagent kits are fixedly installed on the inner walls of both sides of the placement cabinet (2). One side of the testing cabinet (1) has a notch. The inner wall of the bottom of the testing cabinet (1) has a sliding groove, and the inner wall of the sliding groove is slidably connected to a sliding mechanism. A sliding plate (16) for placing reagent kits is fixedly installed on the top of the sliding plate (16). A pull plate (3) is fixedly installed on one side of the top of the sliding plate (16). A door (4) is installed on one side of the placement cabinet (2) via a hinge. A clamping mechanism is installed in the placement cabinet (2) to clamp the reagent kits. A conveying mechanism is installed in the placement cabinet (2) and the detection cabinet (1) to move the clamping mechanism left and right. An adjusting mechanism is installed in the placement cabinet (2) to adjust the clamping mechanism up and down to facilitate clamping the reagent kits on the placement plate (5).

2. The fully automatic liquid phase front-end sample feeder changer according to claim 1, characterized in that, The clamping mechanism includes a second concave plate (12), a second motor (14), a bidirectional lead screw (10), and two clamping plates (7). One side of the second motor (14) is fixedly connected to one side of the second concave plate (12). The two ends of the bidirectional lead screw (10) are rotatably connected to the inner walls of the two sides of the second concave plate (12), respectively. The output end of the second motor (14) passes through one side of the second concave plate (12) and is fixedly connected to one end of the bidirectional lead screw (10). One side of each of the two clamping plates (7) is slidably connected to the inner wall of one side of the second concave plate (12). A first lead screw nut is embedded in one side of the clamping plate (7), and the first lead screw nut is threadedly connected to the bidirectional lead screw (10).

3. The fully automatic liquid phase front-end sample feeder converter according to claim 1, characterized in that, The conveying mechanism includes a first concave plate (8), a first motor, a lead screw (13), and a moving block (9). One side of the first concave plate (8) is slidably connected to the inner wall of one side of the testing cabinet (1) and the placement cabinet (2). One side of the first motor is fixedly connected to one side of the first concave plate (8). One end of the lead screw (13) is fixedly connected to the output end of the first motor. The other end of the lead screw (13) is rotatably connected to the inner wall of one side of the first concave plate (8). A second lead screw nut is embedded in one side of the moving block (9). The second lead screw nut is threadedly connected to the lead screw (13).

4. The fully automatic liquid phase front-end sample feeder changer according to claim 3, characterized in that, The adjustment mechanism includes a threaded rod (15), a third motor, and a connecting block. The bottom end of the threaded rod (15) is rotatably connected to the bottom inner wall of the placement cabinet (2). The top of the third motor is fixedly connected to the top inner wall of the placement cabinet (2). The top end of the threaded rod (15) is fixedly connected to the output end of the third motor. A threaded hole is provided on the connecting block. The threaded rod (15) is threadedly connected to the threaded hole. One side of the first concave plate (8) on one side of the connecting block is fixedly connected.

5. A fully automatic liquid phase front-end sample feeder converter according to claim 3, characterized in that, An electric push rod (11) for driving the clamping plate (7) to move back and forth is fixedly provided on one side of the moving block (9), and the telescopic part of the electric push rod (11) is fixedly connected to one side of the second concave plate (12).

6. The fully automatic liquid phase front-end sample feeder changer according to claim 1, characterized in that, The top of the placement plate (5) is fixedly provided with two limiting strips (6) for limiting the two sides of the reagent kit.

7. A fully automatic liquid phase front-end sample feeder changer according to claim 2, characterized in that, Both clamping plates (7) are fixedly provided with rubber pads on the side that is close to each other to improve the clamping effect.

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