Heparin sodium extraction and inactivation device

By combining a high-pressure sterilization chamber, a heating jacket, and an ultraviolet inactivation tank, the problem of incomplete inactivation of heparin sodium solution was solved, achieving deep inactivation of heparin sodium solution and improving extraction efficiency.

CN224166614UActive Publication Date: 2026-04-28SUZHOU JIANFEI INTESTINE CASING CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
SUZHOU JIANFEI INTESTINE CASING CO LTD
Filing Date
2025-03-10
Publication Date
2026-04-28

AI Technical Summary

Technical Problem

Current technology cannot deeply inactivate and sterilize heparin sodium solution, resulting in excessive bacteria and affecting the extraction effect.

Method used

It employs a combination of a high-pressure sterilization chamber, a heating jacket, and an ultraviolet inactivation tank to achieve deep inactivation through a combination of high-pressure sterilization, boiling high-temperature sterilization, and ultraviolet sterilization.

Benefits of technology

It significantly improves the inactivation effect of heparin sodium solution, ensuring the efficiency and safety of the extraction process.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a heparin sodium extraction inactivation device which comprises a high-pressure sterilization bin, a booster pump is installed outside the high-pressure sterilization bin, an air pressure monitoring meter is installed on one side of the booster pump, and the bottom of the high-pressure sterilization bin is connected with a high-temperature sterilization bin in a sealed mode through a liquid conveying pipeline. One end of the high-temperature sterilization bin is hermetically connected with an ultraviolet inactivation machine tank through a pipeline. According to the utility model, the high-pressure sterilization bin is arranged, so that bacterial substances in a heparin sodium liquid raw material can be conveniently subjected to high-pressure sterilization operation, then the primarily sterilized heparin sodium liquid is conveyed into the high-temperature sterilization bin through the liquid conveying pump, and the liquid is boiled and subjected to high-temperature sterilization through the electric heating pipe, so that a further inactivation effect is achieved; finally, an ultraviolet inactivation machine tank is arranged, and an ultraviolet generator device is mounted in the ultraviolet inactivation machine tank and can be used for emitting ultraviolet rays to further inactivate and sterilize the heparin sodium liquid, so that the inactivation effect of the heparin sodium liquid is improved.
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Description

Technical Field

[0001] This utility model relates to the field of heparin sodium extraction technology, specifically a heparin sodium extraction and inactivation device. Background Technology

[0002] Sodium heparin was the first anticoagulant discovered and isolated for medical use. More than a hundred years after its discovery, it is one of the oldest drugs still used clinically. To date, no synthetic product has been able to completely replace it. It remains the most important anticoagulant and antithrombotic drug and can only be extracted from animal tissues. Sodium heparin can prevent and treat arterial and venous thrombosis and pulmonary embolism. It can be used as an anticoagulant in cardiopulmonary bypass, peritoneal dialysis, or hemodialysis. Recent studies have shown that sodium heparin also has effects such as lowering blood lipids, anticancer, antiviral, anti-inflammatory, anti-allergic, anti-membranous smooth muscle cell proliferation, and reducing blood viscosity.

[0003] Chinese patent document CN222226390U discloses a heparin sodium extraction and inactivation device, relating to the field of heparin sodium extraction technology. The device includes an inactivation mechanism, a cap mechanism, and a cleaning mechanism. The cap mechanism includes an input pipe with a cap groove at its upper end. Four rectangular slots are formed on one side of the cap groove. To disassemble the cap, simply turn a knob through the assembly to move the four slots out of the slots, thus releasing the cap's fixation. This simplifies cap disassembly, facilitating loading and unloading by workers and allowing for easy insertion of heparin sodium raw materials. The device also includes a cleaning mechanism. After inactivation and discharge of the raw materials, a water pump draws water from the tank and sends it into a ring pipe, where nozzles spray water onto the inner wall of the inactivation tank. This continuous flushing of the inner wall eliminates the need for manual cleaning and uses less water, thus conserving water.

[0004] The existing technology mentioned above cannot perform deep inactivation and sterilization of heparin sodium solution, resulting in excessive bacteria in the heparin sodium solution and affecting its extraction effect. Therefore, it is necessary to develop a new heparin sodium extraction and inactivation device. Utility Model Content

[0005] The purpose of this invention is to provide a heparin sodium extraction and inactivation device to solve the problem mentioned in the background art that the prior art cannot perform deep inactivation and sterilization of heparin sodium solution, resulting in excessive bacteria in the heparin sodium solution and affecting its extraction effect.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a heparin sodium extraction and inactivation device, comprising a high-pressure sterilization chamber, a booster pump installed outside the high-pressure sterilization chamber, a pressure monitoring gauge installed on one side of the booster pump, a high-temperature sterilization chamber sealed to the bottom of the high-pressure sterilization chamber via a liquid delivery pipeline, and an ultraviolet inactivation tank sealed to one end of the high-temperature sterilization chamber via a pipeline.

[0007] Preferably, the air delivery end of the booster pump is sealed and connected to a booster air guide pipe via a three-way pipe, and one end of the booster air guide pipe is sealed and connected to the interior of the high-pressure sterilization chamber via a sealing joint.

[0008] Preferably, one end of the pressure monitoring gauge is connected to the interior of the high-pressure sterilization chamber via a pressure measuring pipeline.

[0009] Preferably, an infusion pump is installed on the infusion pipeline, and one end of the infusion pump is connected to the bottom of the high-pressure sterilization chamber through a pipeline.

[0010] Preferably, the high-temperature sterilization chamber and the ultraviolet inactivation tank are connected by a drain pipe, and a drain control valve is installed on the drain pipe.

[0011] Preferably, the high-temperature sterilization chamber is provided with a heating jacket, and an electric heating tube is installed inside the heating jacket.

[0012] Preferably, an ultraviolet generator is installed inside the ultraviolet inactivation tank.

[0013] Compared with the prior art, the beneficial effects of this utility model are:

[0014] This invention features a high-pressure sterilization chamber for convenient high-pressure sterilization of bacteria in the heparin sodium liquid raw material. The pre-sterilized heparin sodium liquid is then transported to a high-temperature sterilization chamber via an infusion pump, where it is boiled using an electric heating element for further inactivation. Finally, an ultraviolet (UV) inactivation tank, equipped with a UV generator, further inactivates and sterilizes the heparin sodium liquid, enhancing the overall inactivation effect. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0016] Figure 2 This is a schematic diagram of the internal installation structure of this utility model;

[0017] Figure 3 This is a top view of the present invention.

[0018] In the diagram: 1. Sealing joint; 2. Booster pump; 3. Booster air pipe; 4. T-joint; 5. Infusion pump; 6. Infusion pipeline; 7. Drainage control valve; 8. High-pressure sterilization chamber; 9. Pressure measuring pipeline; 10. Pressure monitoring gauge; 11. High-temperature sterilization chamber; 12. Drainage pipeline; 13. Ultraviolet inactivation tank; 14. Heating jacket; 15. Electric heating element; 16. Ultraviolet generator. Detailed Implementation

[0019] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.

[0020] Please see Figure 1-3 One embodiment of this utility model is a heparin sodium extraction and inactivation device, which includes a high-pressure sterilization chamber 8, a booster pump 2 installed on the outside of the high-pressure sterilization chamber 8, a pressure monitoring gauge 10 installed on one side of the booster pump 2, a high-temperature sterilization chamber 11 sealed to the bottom of the high-pressure sterilization chamber 8 through an infusion pipeline 6, and an ultraviolet inactivation tank 13 sealed to one end of the high-temperature sterilization chamber 11 through a pipeline.

[0021] Furthermore, the air supply end of the booster pump 2 is sealed and connected to the booster air pipe 3 through the three-way pipe 4. One end of the booster air pipe 3 is sealed and connected to the interior of the high-pressure sterilization chamber 8 through the sealing joint 1. By turning on the booster pump 2, the booster air pipe 3 can continuously pressurize the interior of the high-pressure sterilization chamber 8, ensuring that the interior of the high-pressure sterilization chamber 8 is in a high-pressure state. The sealing joint 1 ensures the sealing performance of the connection and prevents air leakage.

[0022] Furthermore, one end of the pressure monitoring gauge 10 is connected to the internal seal of the high-pressure sterilization chamber 8 through the pressure measuring pipeline 9. By setting up the pressure monitoring gauge 10, it can be used to monitor the internal pressure of the high-pressure sterilization chamber 8 in real time.

[0023] Furthermore, an infusion pump 5 is installed on the infusion pipeline 6. One end of the infusion pump 5 is connected to the bottom of the high-pressure sterilization chamber 8 through a pipeline. By turning on the infusion pump 5, the high-pressure sterilized heparin sodium solution can be discharged into the high-temperature sterilization chamber 11 through the infusion pipeline 6.

[0024] Furthermore, the high-temperature sterilization chamber 11 and the ultraviolet inactivation tank 13 are connected by a drain pipe 12. A drain control valve 7 is installed on the drain pipe 12. By opening the drain control valve 7, the heparin sodium solution after high-temperature sterilization can be discharged into the ultraviolet inactivation tank 13.

[0025] Furthermore, the high-temperature sterilization chamber 11 is equipped with a heating jacket 14, and an electric heating tube 15 is installed inside the heating jacket 14. By turning on the electric heating tube 15, the liquid is boiled and sterilized at high temperature to achieve a further inactivation effect.

[0026] Furthermore, an ultraviolet generator 16 is installed inside the ultraviolet inactivation tank 13. The ultraviolet generator 16 can emit ultraviolet light to perform ultraviolet sterilization and inactivation on the heparin sodium solution inside the ultraviolet inactivation tank 13.

[0027] Working principle: During use, a booster pump 2 is installed on the outside of the autoclave 8. A pressure monitoring gauge 10 is installed on one side of the booster pump 2. By turning on the booster pump 2, continuous pressurization is carried out inside the autoclave 8 through the pressurization air pipe 3, ensuring that the inside of the autoclave 8 is under high pressure. The sealing joint 1 ensures the sealing performance of the connection and prevents air leakage. The autoclave 8 can perform autoclaving on heparin sodium solution. Subsequently, by turning on the infusion pump 5, the autoclaved liver can be delivered through the infusion pipe 6. The sodium heparin solution is discharged into the high-temperature sterilization chamber 11, where it is boiled and sterilized by an electric heating tube 15 to achieve further inactivation. By opening the drain control valve 7, the high-temperature sterilized sodium heparin solution can be discharged into the ultraviolet inactivation tank 13. The ultraviolet inactivation tank 13 is equipped with an ultraviolet generator 16, which can emit ultraviolet light to sterilize and inactivate the sodium heparin solution inside the ultraviolet inactivation tank 13, thereby improving the inactivation effect of the sodium heparin solution.

[0028] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0029] All standard parts used in this application can be purchased from the market. The specific connection methods of each part are all conventional methods such as bolts, rivets, and welding that are mature in the prior art. The machinery, parts and equipment are all conventional models in the prior art. In addition, the circuit connection adopts conventional connection methods in the prior art, and will not be described in detail here.

[0030] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A heparin sodium extraction and inactivation device, comprising a high-pressure sterilization chamber (8), characterized in that, A booster pump (2) is installed on the outside of the high-pressure sterilization chamber (8). A pressure monitoring gauge (10) is installed on one side of the booster pump (2). A high-temperature sterilization chamber (11) is sealed to the bottom of the high-pressure sterilization chamber (8) through an infusion pipe (6). One end of the high-temperature sterilization chamber (11) is sealed to an ultraviolet inactivation tank (13) through a pipeline.

2. The heparin sodium extraction and inactivation device according to claim 1, characterized in that: The air delivery end of the booster pump (2) is sealed and connected to the booster air guide pipe (3) through a three-way pipe (4). One end of the booster air guide pipe (3) is sealed and connected to the interior of the high-pressure sterilization chamber (8) through a sealing joint (1).

3. The heparin sodium extraction and inactivation device according to claim 1, characterized in that: One end of the pressure monitoring meter (10) is connected to the inside of the high-pressure sterilization chamber (8) via a pressure measuring pipeline (9).

4. The heparin sodium extraction and inactivation device according to claim 1, characterized in that: An infusion pump (5) is installed on the infusion pipeline (6), and one end of the infusion pump (5) is connected to the bottom of the high-pressure sterilization chamber (8) through a pipeline.

5. The heparin sodium extraction and inactivation device according to claim 1, characterized in that: The high-temperature sterilization chamber (11) and the ultraviolet inactivation tank (13) are connected by a drain pipe (12), and a drain control valve (7) is installed on the drain pipe (12).

6. The heparin sodium extraction and inactivation device according to claim 1, characterized in that: The high-temperature sterilization chamber (11) is provided with a heating jacket (14) inside, and an electric heating tube (15) is installed inside the heating jacket (14).

7. The heparin sodium extraction and inactivation device according to claim 1, characterized in that: An ultraviolet generator (16) is installed inside the ultraviolet inactivation tank (13).

Citation Information

Patent Citations

  • Heparin sodium extraction and inactivation device

    CN222226390U