High-pressure homogenizing device for preparing external lipidosome

Abstract

The utility model discloses a high-pressure homogenizing device for preparing external lipidosome, which belongs to the technical field of lipidosome processing and comprises a device body, a feed port and a discharge port are arranged on the device body, a vehicle body is arranged on one side of the device body, a water tank and a support are arranged on the top surface of the vehicle body, and a water pump is arranged above the support. A three-way valve is arranged on the outer wall of the device body, the water outlet end of the water pump is communicated with a first connector of the three-way valve through a cleaning pipe, an air blower is arranged below the support and communicated with a second connector of the three-way valve through a drying pipe, and a feeding pipe is arranged on the feeding port and communicated with a third connector of the three-way valve. The three-way valve is controlled, hot water in the water tank is used for cleaning the interior of the device body, the water temperature is controllable, operation is easy and convenient, and the cleaning effect is good; and the interior of the device body is air-dried through an air blower and a drying pipe, the drying efficiency is improved, the drying time is saved, and the production efficiency is improved.

Description

Technical Field

[0001] This utility model relates to the field of liposome processing technology, and in particular to a high-pressure homogenizing device for preparing topical liposomes. Background Technology

[0002] High-pressure homogenizers, also known as "high-pressure fluid nano-homogenizers," allow materials in suspension to flow at high speed through a specially structured cavity under ultra-high pressure. This causes a series of changes in the material's physical, chemical, and structural properties, ultimately achieving homogenization. A high-pressure homogenizer mainly consists of a high-pressure homogenization chamber and a pressurizing mechanism. The high-pressure homogenization chamber has a specially designed geometry. Under the action of the pressurizing mechanism, the high-pressure solution rapidly passes through the homogenization chamber. The material is simultaneously subjected to mechanical forces such as high-speed shearing, high-frequency oscillation, cavitation, and convective impact, as well as corresponding thermal effects. The resulting mechanical and chemical effects induce changes in the physical, chemical, and structural properties of the material's macromolecules, ultimately achieving homogenization.

[0003] After homogenizing liposomes under high pressure, existing high-pressure homogenizers require cleaning the internal cavity of the homogenizer with hot water. However, most existing cleaning methods require boiling water separately and pouring it into the high-pressure homogenizer. This method is not only difficult to control the water temperature, affecting the cleaning effect, but also requires natural air drying after cleaning to ensure that the machine is dry before it can be used normally. The drying time is long, which affects production efficiency. Utility Model Content

[0004] The purpose of this invention is to provide a high-pressure homogenizing device for preparing topical liposomes, which solves the problems of existing high-pressure homogenizing devices, which mostly require boiling water separately and pouring it into the device for cleaning, making it difficult to control the water temperature and affecting the cleaning effect; after cleaning, the device also needs to be air-dried to ensure that it is dry before it can be used normally, which takes a long time and affects production efficiency.

[0005] To solve the above-mentioned technical problems, the present invention adopts the following technical solution:

[0006] This utility model discloses a high-pressure homogenizing device for preparing topical liposomes, comprising a device body with an inlet and an outlet. A vehicle body is mounted on one side of the device body, and a water tank is mounted on the top surface of the vehicle body. The outer wall of the water tank has an inlet and an outlet. A support is mounted on one side of the water tank, and a water pump is mounted above the support. The inlet of the water pump is connected to the outlet. A three-way valve is mounted on the outer wall of the device body, and the outlet of the water pump is connected to the first port of the three-way valve via a cleaning pipe. A blower is mounted below the support, and the blower is connected to the second port of the three-way valve via a drying pipe. A feed pipe is mounted on the inlet, and the feed pipe is connected to the third port of the three-way valve.

[0007] Furthermore, the water tank includes a tank body, a heating tube is installed inside the tank body, and a thermometer is installed on one side of the tank body.

[0008] Furthermore, the top surface of the box is provided with a box cover, and the box cover is provided with a locking component.

[0009] Furthermore, the locking assembly includes a rotary handle rotatably connected to the lid, with the bottom end of the rotary handle extending below the lid. A locking block is connected to the bottom of the rotary handle, and a locking groove matching the locking block is provided at the opening on the top surface of the box.

[0010] Furthermore, quick connectors are provided at the ends of the cleaning pipe, the drying pipe, and the feed pipe, and the three quick connectors are respectively connected to the three ports of the three-way valve.

[0011] Furthermore, the quick connector includes a female connector, a female connector is provided on one side of the female connector, a positioning component is provided on the female connector for locking the female connector, a connecting head is provided on the side of the female connector away from the female connector, and a connecting head is also provided on the side of the female connector away from the female connector. One of the connecting heads is connected to the three-way valve, and the other connecting head is connected to the cleaning pipe, the drying pipe, or the feed pipe.

[0012] Furthermore, the outer wall of the sub-connector is provided with a slot, and two positioning components are symmetrically arranged on the outer wall of the female connector. The positioning component includes a mounting base, which is disposed on the outer wall of the female connector. The mounting base is provided with a locking rod, one end of which is provided with a locking part that matches the slot, and the other end of which is provided with a pull ring.

[0013] Furthermore, a sealing gasket is provided inside the internal mounting cavity of the female connector.

[0014] Compared with the prior art, the beneficial technical effects of this utility model are as follows:

[0015] This invention features a vehicle body on one side of the main body of the device. A water tank, a water pump, and a blower are mounted on the top surface of the vehicle body. A three-way valve is installed on the outer wall of the main body. The outlet of the water pump is connected to the first port of the three-way valve via a cleaning pipe. The blower is connected to the second port of the three-way valve via a drying pipe, and the feed pipe is connected to the third port of the three-way valve. By controlling the three-way valve, hot water from the water tank is used to clean the interior of the main body. The water temperature is controllable, operation is simple and convenient, and the cleaning effect is excellent. The blower and drying pipe are used to dry the interior of the main body, improving drying efficiency, saving drying time, and increasing production efficiency. Attached Figure Description

[0016] The present invention will be further described below with reference to the accompanying drawings.

[0017] Figure 1 This is a front view of the high-pressure homogenizing apparatus for preparing topical liposomes according to this invention;

[0018] Figure 2 This is a cross-sectional view of the water tank of this utility model;

[0019] Figure 3 This is a three-dimensional structural diagram of the water tank of this utility model;

[0020] Figure 4 This is a three-dimensional structural diagram of the quick connector of this utility model in an exploded state.

[0021] Figure 5 This is a cross-sectional view of the female connector of this utility model.

[0022] Explanation of reference numerals in the attached drawings: 1. Device body; 1-1. Inlet; 1-2. Outlet; 2. Inlet pipe; 3. Quick connector; 3-1. Female connector; 3-1-1. Mounting base; 3-1-2. Locking rod; 3-1-2-1. Locking part; 3-1-3. Pull ring; 3-2. Sub-connector; 3-2-1. Slot; 3-3. Connector; 3-4. Sealing gasket; 4. Three-way valve; 5. Car body; 6. Water tank; 6-1. Box body; 6-1-1. Locking groove; 6-2. Water inlet; 6-3. Water outlet; 6-4. Heating tube; 6-5. Thermometer; 6-6. Box cover; 6-7. Rotary handle; 6-8. Locking block; 7. Water pump; 8. Cleaning pipe; 9. Blower; 10. Drying pipe; 11. Bracket. Detailed Implementation

[0023] like Figure 1-5As shown, a high-pressure homogenizing device for preparing topical liposomes includes a device body 1. The device body 1 is connected to an inlet 1-1 and an outlet 1-2. The device body 1 is a high-pressure homogenizing device, which is existing technology; its internal structure will not be described in detail here. During use, the operator can directly introduce the material to be homogenized into the device body 1 through the inlet 1-1 for homogenization. The homogenized material is discharged through the outlet 1-2. A vehicle body 5 is provided on one side of the device body 1. A water tank 6 is installed on the top surface of the vehicle body 5. An inlet 6-2 and an outlet 6-3 are connected to the outer wall of the water tank 6. A support is provided on one side of the water tank 6. 11. A bracket 11 is connected to the top surface of the vehicle body 5. A water pump 7 is installed above the bracket 11. The inlet of the water pump 7 is connected to the outlet 6-3. A three-way valve 4 is fixed to the outer wall of the device body 1 by a clamp. The outlet of the water pump 7 is connected to the first interface of the three-way valve 4 through a cleaning pipe 8. A blower 9 is installed below the bracket 11. The blower 9 is installed on the top surface of the vehicle body 5 by a mounting bracket. The blower 9 is connected to the second interface of the three-way valve 4 through a drying pipe 10. A feed pipe 2 is installed on the feed inlet 1-1. The feed pipe 2 is connected to the third interface of the three-way valve 4.

[0024] like Figure 2 , 3 As shown, the water tank 6 includes a tank body 6-1. A heating tube 6-4 is installed inside the tank body 6-1. The heating tube 6-4 is configured as a coil to increase the contact area with water, which is beneficial for improving heating efficiency. A thermometer 6-5 is installed on one side of the tank body 6-1 to detect the water temperature. A tank cover 6-6 is hinged to the top surface of the tank body 6-1. A locking assembly is installed on the tank cover 6-6. The locking assembly includes a rotating handle 6-7, which is rotatably connected to the tank cover 6-6. The bottom end of the rotating handle 6-7 extends below the tank cover 6-6, and the bottom of the rotating handle 6-7 is connected to... A locking block 6-8 is attached, and a locking groove 6-1-1 matching the locking block 6-8 is provided at the top opening of the box body 6-1. Specifically, the locking part of the locking block 6-8 is fan-shaped, and the cross-section of the locking groove 6-1-1 is also fan-shaped. The notch on the lid 6-6 matches the protrusion on the top surface of the box body 6-1. When the lid 6-6 is closed, the rotating handle 6-7 is rotated, which drives the locking block 6-8 to rotate, and the locking block 6-8 enters the locking groove 6-1-1, thereby fixing the position of the lid 6-6. The lid 6-6 facilitates the addition of cleaning agent into the box body 6-1.

[0025] The ends of the cleaning pipe 8, the drying pipe 10 and the feed pipe 2 are all equipped with quick connectors 3, and the three quick connectors 3 are respectively connected to the three ports of the three-way valve 4.

[0026] like Figure 4 , 5 As shown, the quick connector 3 includes a female connector 3-1, and a matching female connector 3-2 is installed on one side of the female connector 3-1. A positioning component for locking the female connector 3-2 is installed on the female connector 3-1. A connector 3-3 is threadedly connected to the side of the female connector 3-2 away from the female connector 3-1. A connector 3-3 is also threadedly connected to the side of the female connector 3-1 away from the female connector 3-2. One connector 3-3 is connected to the three-way valve 4, and the other connector 3-3 is connected to the cleaning pipe 8, the drying pipe 10, or the feed pipe 2.

[0027] The outer wall of the sub-connector 3-2 is provided with a slot 3-2-1. Two positioning components are symmetrically arranged on the outer wall of the female connector 3-1. Each positioning component includes a mounting base 3-1-1, which is connected to the outer wall of the female connector 3-1. A locking rod 3-1-2 is connected to the mounting base 3-1-1 via a rotating shaft. One end of the locking rod 3-1-2 is connected to a locking part 3-1-2-1 that matches the slot 3-2-1, and the other end of the locking rod 3-1-2 is connected to a pull ring 3-1-3.

[0028] like Figure 5 As shown, a sealing gasket 3-4 is installed inside the internal mounting cavity of the female connector 3-1. The sealing gasket 3-4 contacts the end face of the female connector 3-2 to improve the sealing performance of the connection.

[0029] The working process of this utility model is as follows:

[0030] When in use, the staff can choose to directly feed the material to be homogenized into the feed port 1-1 and into the main body 1 of the device for homogenization. The homogenized material is discharged from the discharge port 1-2.

[0031] After a period of use, the inside of the device body 1 needs to be cleaned. Connect the feed pipe 2 to the third port of the three-way valve 4, add water to the box 6-1 through the water inlet 6-2, and heat the water using the heating pipe 6-4. Observe the thermometer 6-5. After the water is heated to a suitable temperature, open the three-way valve 4. The first port of the three-way valve 4 is connected to the cleaning pipe 8. The water pump 7 pumps hot water into the cleaning pipe 8. The hot water enters the inside of the device body 1 through the feed pipe 2 to rinse the inside of the device body 1. The rinsed water is discharged through the outlet 1-2. Operate the three-way valve 4 to connect the drying pipe 10 to the second port of the three-way valve 4. Close the first port of the three-way valve 4. Use the blower 9 to blow air into the feed pipe 2. The air enters the inside of the device body 1 to dry the inside of the device body 1. The device body 1 can be put back into operation after it is dry.

[0032] The embodiments described above are merely preferred embodiments of the present utility model and are not intended to limit the scope of the present utility model. Various modifications and improvements made to the technical solutions of the present utility model by those skilled in the art without departing from the spirit of the present utility model should fall within the protection scope defined by the claims of the present utility model.

Claims

1. A high-pressure homogenizing device for preparing topical liposomes, comprising a device body (1), wherein the device body (1) is provided with an inlet (1-1) and an outlet (1-2), characterized in that: A vehicle body (5) is provided on one side of the device body (1). A water tank (6) is provided on the top surface of the vehicle body (5). An inlet (6-2) and an outlet (6-3) are provided on the outer wall of the water tank (6). A bracket (11) is provided on one side of the water tank (6). A water pump (7) is provided above the bracket (11). The inlet of the water pump (7) is connected to the outlet (6-3). A three-way valve (4) is provided on the outer wall of the device body (1). The outlet of the water pump (7) is connected to the first interface of the three-way valve (4) through a cleaning pipe (8). A blower (9) is provided below the bracket (11). The blower (9) is connected to the second interface of the three-way valve (4) through a drying pipe (10). A feed pipe (2) is provided on the feed inlet (1-1). The feed pipe (2) is connected to the third interface of the three-way valve (4).

2. The high-pressure homogenizing apparatus for preparing topical liposomes according to claim 1, characterized in that: The water tank (6) includes a tank body (6-1), a heating tube (6-4) is installed inside the tank body (6-1), and a thermometer (6-5) is installed on one side of the tank body (6-1).

3. The high-pressure homogenizing apparatus for preparing topical liposomes according to claim 2, characterized in that: The top surface of the box (6-1) is provided with a box cover (6-6), and a locking component is provided on the box cover (6-6).

4. The high-pressure homogenizing apparatus for preparing topical liposomes according to claim 3, characterized in that: The locking assembly includes a rotating handle (6-7), which is rotatably connected to the lid (6-6). The bottom end of the rotating handle (6-7) extends to the bottom of the lid (6-6). A locking block (6-8) is connected to the bottom of the rotating handle (6-7). A locking groove (6-1-1) matching the locking block (6-8) is provided at the top opening of the box body (6-1).

5. The high-pressure homogenizing apparatus for preparing topical liposomes according to claim 1, characterized in that: The ends of the cleaning pipe (8), the drying pipe (10) and the feed pipe (2) are all provided with quick connectors (3), and the three quick connectors (3) are respectively connected to the three ports of the three-way valve (4).

6. The high-pressure homogenizing apparatus for preparing topical liposomes according to claim 5, characterized in that: The quick connector (3) includes a female connector (3-1), a female connector (3-2) is provided on one side of the female connector (3-1), a positioning component for locking the female connector (3-2) is provided on the female connector (3-1), a connector (3-3) is provided on the side of the female connector (3-2) away from the female connector (3-1), and a connector (3-3) is also provided on the side of the female connector (3-1) away from the female connector (3-2). One connector (3-3) is connected to the three-way valve (4), and the other connector (3-3) is connected to the cleaning pipe (8), the drying pipe (10), or the feed pipe (2).

7. The high-pressure homogenizing apparatus for preparing topical liposomes according to claim 6, characterized in that: The outer wall of the sub-connector (3-2) is provided with a slot (3-2-1), and two positioning components are symmetrically arranged on the outer wall of the female connector (3-1). The positioning components include a mounting base (3-1-1), which is located on the outer wall of the female connector (3-1). A locking rod (3-1-2) is provided on the mounting base (3-1-1). One end of the locking rod (3-1-2) is provided with a locking part (3-1-2-1) that matches the slot (3-2-1), and the other end of the locking rod (3-1-2) is provided with a pull ring (3-1-3).

8. The high-pressure homogenizing apparatus for preparing topical liposomes according to claim 7, characterized in that: A sealing gasket (3-4) is provided inside the mounting cavity of the female connector (3-1).

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