Pathological staining jar capable of monitoring water-containing state

By installing a transparent mesh sheet and a base plate in the pathological staining jar to create a water content monitoring space, and using color-changing substances to determine the moisture content, the problem of difficulty in distinguishing moisture in xylene solution is solved, thus improving the operational efficiency and diagnostic accuracy of the pathological staining jar.

CN224231400UActive Publication Date: 2026-05-12THE SECOND PEOPLES HOSPITAL OF BEILUN DISTRICT NINGBO
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
THE SECOND PEOPLES HOSPITAL OF BEILUN DISTRICT NINGBO
Filing Date
2025-04-02
Publication Date
2026-05-12

AI Technical Summary

Technical Problem

It is difficult to discern with the naked eye whether the xylene solution in the existing pathological staining jar contains water, resulting in poor slide clearing and affecting diagnostic efficiency.

Method used

A transparent mesh sheet is installed in the pathological staining jar to form a water content monitoring space with the base plate. The discoloration material is placed there, and anhydrous cobalt chloride is impregnated using a porous silica carrier to change the color. The presence of moisture is determined by the color change. The transparent mesh sheet restricts the position of the discoloration material to prevent it from tipping over.

Benefits of technology

It enables intuitive judgment of whether the reagent in the xylene staining tank needs to be replaced, reduces the problems of slides caused by moisture, and improves diagnostic efficiency and work convenience.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a pathologic staining jar capable of monitoring a water-containing state, which comprises a jar body, a transparent grid piece is transversely arranged at a position, close to a bottom plate, of the lower part of the jar body, a water-containing monitoring space is formed between the transparent grid piece and the bottom plate, a plurality of color-changing objects are placed in the water-containing monitoring space, and the color-changing objects are arranged in the jar body. The color of the color-changing object changes after absorbing water, a hollow hole is formed in a bottom plate of the vat body, a detachable lower cover is installed at the position of the hollow hole, the transparent grid piece can limit the position of the color-changing object, the color-changing object cannot be poured out due to pouring of a reagent in the pathological staining vat, and therefore the color-changing object is convenient to use. Due to the fact that the density of water is larger than that of the xylene reagent, the water can be deposited in the water content monitoring space, the color-changing object can be seen from the opening in the upper end of the cylinder body after absorbing water and changing color, and whether the reagent in the xylene dyeing cylinder needs to be replaced or not can be visually judged.
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Description

Technical Field

[0001] This utility model relates to the field of pathological staining vat technology, specifically a pathological staining vat that can monitor the water content. Background Technology

[0002] HE staining, an indispensable part of histopathology, greatly facilitates microscopic observation of tissues due to its ability to stain different tissue components with various colors. In fully automated HE staining processes, the staining racks and slides, after being washed, often carry a certain amount of moisture into the subsequent gradient ethanol staining tanks. Simultaneously, as ambient humidity rises, open ethanol staining tanks easily absorb moisture from the air. Crucially, if moisture is introduced into the tanks used in the final two anhydrous ethanol staining steps, this moisture will be carried into the subsequent xylene staining tank. Since xylene and water are immiscible at room temperature, excessive moisture will cause stratification. Once moisture seeps into the xylene reagent tank, the clearing process of the slides will be significantly compromised, making it difficult to completely remove moisture from the slides, thus interfering with the mounting process using neutral resin. This results in the slides appearing under the microscope as brownish bubbles of varying sizes, or even as opaque or cloudy surfaces, severely hindering the diagnostician's comprehensive examination of the tissue morphology and significantly slowing down the speed and efficiency of slide reading. Faced with such problems, slides often need to be remade or undergo a tedious process of dehydration, clearing, and mounting, which undoubtedly adds a heavy workload to pathology technicians. The root cause of these problems is that xylene and anhydrous ethanol are both transparent and colorless liquids, making it difficult for technicians to determine with the naked eye whether the reagents contain water and when to change them appropriately. Therefore, a device that can monitor the presence of moisture in the pathology staining jar is needed. Utility Model Content

[0003] This invention provides a pathological staining vat that can monitor the water content, which can solve the problem that it is difficult to distinguish with the naked eye whether there is water in the xylene solution in the existing pathological staining vat.

[0004] To achieve the above objectives, this utility model provides the following technical solution: a pathological staining jar capable of monitoring water content, comprising a jar body, wherein a transparent mesh sheet is horizontally installed at the lower part of the jar body near the bottom plate, forming a water content monitoring space between the transparent mesh sheet and the bottom plate, wherein several color-changing substances are placed in the water content monitoring space, wherein the color-changing substances change color after absorbing water, wherein the bottom plate of the jar body is provided with perforations, and a detachable lower cover is installed at the perforations, wherein the transparent mesh sheet can restrict the position of the color-changing substances, preventing the color-changing substances from being poured out due to the spillage of reagents inside the pathological staining jar, and since the density of water is greater than that of xylene reagent, it will settle in the water content monitoring space, and the color-changing substances can be seen from the upper opening of the jar body after absorbing water and changing color, so it is possible to intuitively determine whether the reagents in the xylene staining jar need to be replaced.

[0005] Preferably, the color-changing material uses porous silica as a carrier and is impregnated with anhydrous cobalt chloride on its surface, which has a strong hygroscopic capacity and a keen sensitivity to changes in humidity.

[0006] Preferably, the base plate includes a horizontal section in the middle and inclined sections on both sides of the horizontal section. The inclined sections extend to the side wall of the cylinder body, which can gather the discolored material on the upper side of the horizontal section for easy centralized observation.

[0007] Preferably, a plurality of limiting grooves are arranged side by side on the upper side of the horizontal part, and the color-changing material is placed on the limiting grooves, which increase the resistance to the drifting of the color-changing material.

[0008] Preferably, the discoloring substance is spherical, and the bottom cross-section of the limiting groove is arc-shaped, which facilitates the rapid discharge of the discoloring substance along with the xylene reagent.

[0009] Preferably, a cylinder head is provided at the upper end of the cylinder body.

[0010] Preferably, the upper end of the cylinder is rotatably connected to a lifting rod, which facilitates fixing and adjusting the position of the pathological staining cylinder.

[0011] Compared with the prior art, the beneficial effects of this utility model are:

[0012] Existing pathology staining tanks can be modified. The transparent mesh can restrict the position of discolored substances, preventing them from spilling out when reagents are poured out of the staining tank. Since water is denser than xylene, it will settle in the water-containing monitoring space. After the discolored substances absorb water and change color, they can be seen from the opening at the top of the tank, allowing for a direct assessment of whether the reagents in the xylene staining tank need to be replaced. Attached Figure Description

[0013] Figure 1This is a three-dimensional structural diagram of the present invention;

[0014] Figure 2 This is a structural diagram of the main body of this utility model;

[0015] Figure 3 This is a front sectional view of the present invention;

[0016] Figure 4 This is a partially enlarged cross-sectional view of the present invention;

[0017] Figure 5 This is a top view of the structure of this utility model.

[0018] Figure label:

[0019] 1. Cylinder block, 2. Lower cover, 3. sloping part, 4. Color-changing material, 5. Limiting groove, 6. Transparent mesh sheet, 7. Lifting rod, 8. Water content monitoring space, 9. Horizontal part, 10. Cylinder head. Detailed Implementation

[0020] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention.

[0021] like Figure 1-5 As shown, this utility model provides the following technical solution to solve the problem that it is difficult to distinguish whether there is water in the xylene solution in the existing pathological staining tank with the naked eye: a pathological staining tank that can monitor the water content, including a tank body 1. A transparent mesh sheet 6 is horizontally installed at the lower part of the tank body 1 near the bottom plate. The transparent mesh sheet 6 and the bottom plate form a water content monitoring space 8. Several color-changing substances 4 are placed in the water content monitoring space 8. The color-changing substances 4 change color after absorbing water. The bottom plate of the tank body 1 is provided with a hollow hole. A detachable lower cover 2 is installed at the hollow hole. The transparent mesh sheet 6 can restrict the position of the color-changing substances 4. The color-changing substances 4 will not be poured out due to the pouring of reagents inside the pathological staining tank. Since the density of water is greater than that of xylene reagent, it will settle in the water content monitoring space 8. After the color-changing substances 4 absorb water and change color, it can be seen from the upper opening of the tank body 1. Therefore, it is possible to intuitively determine whether the reagents in the xylene staining tank need to be replaced.

[0022] Specifically, the transparent mesh sheet 6 can be installed separately into the cylinder 1. Steps can be provided on the inner wall of the cylinder 1 to support and fix the transparent mesh sheet 6. The transparent mesh sheet 6 has evenly distributed round holes with a diameter of 0.2 cm and a thickness of 0.15 cm. A cylinder cover 10 is provided at the upper end of the cylinder 1, and a lifting rod 7 is rotatably connected to the upper end of the cylinder 1 to facilitate fixing and adjusting the position of the pathology staining cylinder.

[0023] The lower cover 2 can be threaded to the bottom of the cylinder body 1. The bottom of the cylinder body 1 is provided with a threaded hole seat extending downwards. The lower cover 2 is threaded to the threaded hole seat. The installation and removal of the lower cover 2 can be achieved simply by rotating the lower cover 2.

[0024] In practical applications, the transparent mesh sheet 6 can also be integrated with the lower part and base plate of the cylinder body 1, and installed as a separate component with the existing pathological staining cylinder.

[0025] In this embodiment, the color-changing material 4 uses porous silica as a carrier and is impregnated with anhydrous cobalt chloride on its surface. It has a strong hygroscopic capacity and a keen sensitivity to changes in humidity. Under normal conditions, it appears as a deep blue color, but when water appears in the tank, its color will gradually change from deep blue to pink.

[0026] Technicians can then visually determine whether the reagents in the xylene staining tank need to be replaced through the transparent mesh observation window. When the color-changing substance 4 appears slightly pale blue, it means that a small amount of moisture is present; and when most of the color-changing substance 4 turns pink, the reagents should be replaced immediately.

[0027] The height of the water content monitoring space 8 is 0.5 cm. The base plate includes a horizontal part 9 located in the middle and inclined parts 3 set on both sides of the horizontal part 9. The inclined parts 3 extend to the side wall of the cylinder 1, which can gather the discolored substance 4 on the upper side of the horizontal part 9 for easy centralized observation. The horizontal part 9 can be 6 cm long and 4.2 cm wide.

[0028] In this embodiment, a plurality of limiting grooves 5 are arranged side by side on the upper side of the horizontal part 9, and the color-changing material 4 is placed on the limiting grooves 5. The limiting grooves 5 increase the resistance to the drifting of the color-changing material 4.

[0029] In this embodiment, the color-changing substance 4 is spherical, and the bottom cross-section of the limiting groove 5 is arc-shaped, which facilitates the rapid discharge of the color-changing substance 4 along with the xylene reagent. The diameter of the color-changing substance 4 is 0.3 to 0.5 cm.

[0030] When changing reagents, simply open the lower cover 2. Following the principle of hydrostatic pressure, the xylene at the bottom will flow out first, causing the discoloration agent 4 to be discharged quickly, which greatly facilitates the technician's work of changing the discoloration agent 4.

[0031] It should be noted that all directional indicators (such as up, down, left, right, front, back, etc.) in this utility model embodiment are only used to explain the relative positional relationship and movement of each component in a certain specific posture (as shown in the figure). If the specific posture changes, the directional indicator will also change accordingly.

[0032] Furthermore, in this utility model, the use of terms such as "first," "second," etc., is for descriptive purposes only and should not be construed as indicating or implying their relative importance or implicitly specifying the number of technical features indicated. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this utility model, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly and specifically defined.

[0033] In this utility model, unless otherwise explicitly specified and limited, the terms "connection," "fixing," etc., should be interpreted broadly. For example, "fixing" can mean a fixed connection, a detachable connection, or an integral part; it can mean a mechanical connection or an electrical connection; it can mean a direct connection or an indirect connection through an intermediate medium; it can mean the internal communication of two components or the interaction between two components, unless otherwise explicitly limited. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0034] Furthermore, the technical solutions of the various embodiments of this utility model can be combined with each other, but only if they are based on the ability of those skilled in the art to implement them. When the combination of technical solutions is contradictory or cannot be implemented, it should be considered that such combination of technical solutions does not exist and is not within the scope of protection claimed by this utility model.

Claims

1. A pathological staining jar capable of monitoring water content, comprising a jar body (1), wherein a transparent mesh sheet (6) is horizontally installed at the lower part of the jar body (1) near the bottom plate, wherein a water content monitoring space (8) is formed between the transparent mesh sheet (6) and the bottom plate, wherein a plurality of color-changing substances (4) are placed in the water content monitoring space (8), wherein the color-changing substances (4) change color after absorbing water, wherein a perforated hole is provided on the bottom plate of the jar body (1), and a detachable lower cover (2) is installed at the perforated hole.

2. The pathological staining vat with monitorable water content according to claim 1, characterized in that: The color-changing material (4) uses porous silica as a carrier and is impregnated with anhydrous cobalt chloride on its surface.

3. The pathological staining vat with monitorable water content according to claim 1, characterized in that: The base plate includes a horizontal portion (9) located in the middle and inclined portions (3) provided on both sides of the horizontal portion (9), the inclined portions (3) extending to the side wall of the cylinder body (1).

4. The pathological staining vat with monitorable water content according to claim 3, characterized in that: Multiple limiting grooves (5) are arranged side by side on the upper side of the horizontal part (9), and the color-changing material (4) is placed on the limiting grooves (5).

5. The pathological staining vat with monitorable water content according to claim 4, characterized in that: The color-changing material (4) is spherical, and the bottom cross section of the limiting groove (5) is arc-shaped.

6. The pathological staining vat with monitorable water content according to claim 1, characterized in that: The cylinder body (1) is provided with a cylinder head (10) at its upper end.

7. The pathological staining vat with monitorable water content according to claim 6, characterized in that: The upper end of the cylinder (1) is rotatably connected to a lifting rod (7).