Ginseng polypeptide separation and purification device

Abstract

The utility model relates to the technical field of ginseng polypeptide production, in particular to a ginseng polypeptide separation and purification device which comprises a shell, a shell cover, a panel and a plurality of dialysis bags, the shell cover is arranged at the opening end of the shell, a feeding port is formed in the shell cover, the panel is arranged on the surface of the feeding port in a covering mode, a plurality of clamping grooves are formed in the panel, and the dialysis bags are arranged in the clamping grooves. Clamping grooves are formed in the shell cover, bag openings of the dialysis bags are inserted into the clamping grooves and are flattened and sealed inwards through the clamping grooves, positioning columns are installed on the sides, located in the clamping grooves, of the panel, positioning rings are installed on the two sides of the openings of the dialysis bags and sleeve the positioning columns, and a pushing mechanism for driving the panel to move and driving the dialysis bags to swing is installed on the shell cover. The bag opening can be flattened and sealed through the clamping groove, and after the positioning ring on the dialysis bag is sleeved on the positioning column, the dialysis bag can be directly hung, so that the dialysis bag can be immersed in deionized water and can be quickly separated in a swinging manner.

Description

Technical Field

[0001] This utility model relates to the field of ginseng polypeptide production technology, specifically to a ginseng polypeptide separation and purification device. Background Technology

[0002] Ginseng polypeptides are a class of small molecule active peptides extracted from ginseng. They are composed of multiple amino acids linked by peptide bonds and have various biological activities such as anti-oxidation, immune regulation, and metabolism promotion. They have become a research hotspot in the fields of health products, skin care products, and medicine in recent years.

[0003] Currently, in the process of extracting ginseng peptides, separation and purification are carried out. In order to extract large-volume samples, dialysis bags are used. However, the operation of current dialysis bags is relatively cumbersome. They cannot be quickly suspended above deionized water, which affects the separation efficiency. Furthermore, they cannot be quickly removed after installation, which affects the subsequent disassembly of the dialysis bags. Summary of the Invention

[0004] The technical problem to be solved by this utility model is to provide a ginseng polypeptide separation and purification device, in which the dialysis bag can be flattened and sealed by the clamping groove, and is sleeved on the positioning column by the positioning ring, which greatly facilitates its suspension and subsequent disassembly, so as to solve the problems mentioned in the background art.

[0005] This utility model is achieved through the following technical solution: a ginseng polypeptide separation and purification device, comprising a shell, a shell cover, a panel, and multiple dialysis bags. The shell cover is disposed on the open end of the shell and has a feed inlet. The panel covers the surface of the feed inlet and has multiple clamping grooves. The dialysis bags are disposed inside the shell and are all perpendicularly opposite to the clamping grooves. The openings of the dialysis bags are all inserted into the clamping grooves and are flattened and sealed by the clamping grooves. A positioning post is installed on one side of the panel located in the clamping groove. Positioning rings are installed on both sides of the opening of the dialysis bags and are sleeved on the positioning posts. A pushing mechanism is installed on the shell cover to drive the panel to move and the dialysis bags to swing.

[0006] As a preferred technical solution, the driving mechanism includes an electric push rod, a fixed base, multiple positioning rods, multiple compression springs, and multiple limiting plates. The limiting plates are all arranged in an "L" shape and are located at both ends of the panel. One end of each limiting plate covers the top surface of the panel. The fixed base is installed at one end of the cover and has multiple positioning holes. The positioning rods pass through the positioning holes and are installed on one side of the limiting plate. The compression springs are all sleeved on the outside of the positioning rods. One end of each compression spring is installed on the fixed base, and the other end is installed on one side of the limiting plate. The electric push rod is installed on the other end of the cover, and the piston rod of the electric push rod is fixedly connected to the limiting plate on the other side.

[0007] As a preferred technical solution, a horizontal groove is provided on the surface of the cover, a slide bar is installed on the inner side of the panel opposite the groove, the slide bar is slidably disposed in the groove, and a handle is installed on the outer side of the panel.

[0008] As a preferred technical solution, an inlet pipe is installed on one side of the housing, and an outlet pipe is installed on the other side of the housing. Valves are installed on both the inlet and outlet pipes.

[0009] As a preferred technical solution, the dialysis bags are all designed with a columnar structure, and the inside of each dialysis bag contains ginseng polypeptide solution.

[0010] As a preferred technical solution, the length and width of the panel are set to be greater than the length and width of the feed inlet.

[0011] As a preferred technical solution, a base is installed at the end of the housing away from the cover.

[0012] The beneficial effects of this utility model are as follows: In this utility model, the opening of the dialysis bag can be inserted into the clamping groove, which can flatten and seal the opening. After the positioning ring on the dialysis bag is fitted onto the positioning column, the dialysis bag can be directly suspended, allowing it to be immersed in deionized water. The separation operation can be carried out quickly by swinging. Small molecules (such as salts) in the ginseng polypeptide solution diffuse through the membrane, while large molecules (such as proteins and polypeptides) remain in the bag to complete the purification step. Furthermore, after lifting the panel, the dialysis bag can be quickly disassembled, facilitating the subsequent collection of the solution. Attached Figure Description

[0013] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0014] Figure 2 This is a schematic diagram of the structure of this utility model after the panel is removed;

[0015] Figure 3 This is a bottom view of the present invention after the casing has been removed;

[0016] Figure 4 This is a schematic diagram of the installation structure of the dialysis bag of this utility model.

[0017] In the diagram, 1. Shell; 2. Shell cover; 3. Panel; 4. Clamping groove; 5. Dialysis bag; 6. Positioning ring; 7. Positioning post; 8. Limiting plate; 9. Compression spring; 10. Fixing base; 11. Positioning rod; 12. Inlet pipe; 13. Outlet pipe; 14. Slide groove; 15. Electric push rod; 16. Handle; 17. Base; 18. Feed inlet; 19. Slide bar. Detailed Implementation

[0018] The embodiments of this utility model are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this utility model, and should not be construed as limiting this utility model.

[0019] like Figure 1 , Figure 2 , Figure 3 and Figure 4 As shown, this utility model discloses a ginseng polypeptide separation and purification device, comprising a shell 1, a shell cover 2, a panel 3, and multiple dialysis bags 5. The shell cover 2 is disposed on the open end of the shell 1 and has a feed inlet 18. The panel 3 covers the surface of the feed inlet 18 and has multiple clamping grooves 4. The dialysis bags 5 are disposed inside the shell 1 and are all perpendicularly opposite to the clamping grooves 4. The openings of the dialysis bags 5 are all inserted into the clamping grooves 4 and are all flattened and sealed by the clamping grooves 4. Positioning posts 7 are installed on one side of the panel 3 located in the clamping grooves 4. Positioning rings 6 are installed on both sides of the opening of the dialysis bags 5 and are sleeved on the positioning posts 7. A pushing mechanism is installed on the shell cover 2 to drive the panel 3 to move and the dialysis bags 5 to swing.

[0020] In this embodiment, the pushing mechanism includes an electric push rod 15, a fixed base 10, multiple positioning rods 11, multiple compression springs 9, and multiple limiting plates 8. The limiting plates 8 are all arranged in an "L" shape and are located at both ends of the panel 3. One end of each limiting plate 8 covers the top surface of the panel 3. The fixed base 10 is installed at one end of the cover 2 and has multiple positioning holes. The positioning rods 11 pass through the positioning holes and are installed on one side of the limiting plate 8. The compression springs 9 are all sleeved on the outside of the positioning rods 11. One end of each compression spring 9 is installed on the fixed base 10, and the other end is installed on one side of the limiting plate 8. The electric push rod 15 is installed on the other end of the cover 2, and the piston rod of the electric push rod 15 is fixedly connected to the limiting plate 8 on the other side.

[0021] In this embodiment, a sliding groove 14 is provided horizontally on the surface of the cover 2, and a sliding strip 19 is installed on the inner side of the panel 3 opposite to the sliding groove 14. The sliding strip 19 is slidably disposed in the sliding groove 14. A handle 16 is installed on the outer side of the panel 3. The handle facilitates lifting the panel, while the sliding groove and the sliding table can horizontally position the panel to ensure the stability of the panel when it is moved laterally.

[0022] In this embodiment, an inlet pipe 12 is installed on one side of the housing 1, and an outlet pipe 13 is installed on the other side of the housing 1. Valves are installed on both the inlet pipe 12 and the outlet pipe 13. After a long period of separation, the valve on the outlet pipe can be opened to drain the internal deionized water. After all the water has been drained, the valve is closed again. The inlet pipe is connected to a container storing deionized water through a flexible hose. Therefore, after opening the valve on the inlet pipe, new deionized water can be injected into the housing through the inlet pipe to replace the deionized water and ensure the separation quality.

[0023] In this embodiment, all dialysis bags 5 are arranged in a columnar structure, and each dialysis bag 5 contains a ginseng polypeptide solution.

[0024] In this embodiment, the length and width of the panel 3 are set to be greater than the length and width of the feed inlet 18, so as to prevent the panel from entering the feed inlet.

[0025] In this embodiment, a base 17 is installed at the end of the housing 1 away from the cover 2. The base increases the contact area with the tabletop to ensure the stability of the placement.

[0026] The clamping groove has chamfers on both sides of the opening. When in use, the dialysis bag containing ginseng polypeptide solution is flattened inward and inserted into the clamping groove. The inner wall of the clamping groove can further flatten the bag opening and seal it. After the bag opening is bent, its positioning ring can be fitted onto the positioning post. The positioning ring and positioning post can position the dialysis bag so that the dialysis bag can be suspended on the panel.

[0027] After the above is completed, push one of the limiting plates outward to move the limiting plate outward along the positioning rod, increasing the distance between the limiting plates. At this time, the dialysis bag can pass through the feed port into the interior of the shell and be immersed in deionized water. The panel itself is placed on the shell cover and enters between the limiting plates. After releasing one of the limiting plates, the rebound of the compression spring can rebound the limiting plate on one side and hold the two ends of the panel against it. One side of the limiting plate will cover the surface of the panel due to bending, so as to ensure the vertical stability of the panel. The slide on the inner side of the panel can be inserted into the slide groove. The slide groove and the slide table can ensure the lateral stability of the panel.

[0028] After the piston rod of the electric push rod reciprocates, it can push the panel, causing the panel to move along the slide. The return of the compression spring can push the panel back. The back-and-forth movement of the panel can make the dialysis bag swing continuously, allowing small molecules (such as salt) in the ginseng polypeptide solution to quickly diffuse through the membrane, while large molecules (such as proteins and polypeptides) are retained in the bag, thus completing the purification step.

[0029] After separation and purification are completed, push the limiting plate outward again so that the distance between the limiting plates is greater than the length of the panel. At this time, the panel moves upward and the dialysis bag is taken out of the shell along the feed port. After the bag opening is lifted, the positioning ring can be disengaged from the positioning column. Pull the dialysis bag longitudinally again to remove the dialysis bag from the clamping groove, which makes it easy to disassemble.

[0030] The above description is merely a specific embodiment of this utility model, but the protection scope of this utility model is not limited thereto. Any changes or substitutions conceived without inventive effort should be included within the protection scope of this utility model. Therefore, the protection scope of this utility model should be determined by the scope defined in the claims.

Claims

1. A ginseng polypeptide separation and purification device, characterized in that: The application relates to a dialysis bag device, which comprises a shell (1), a shell cover (2), a panel (3) and a plurality of dialysis bags (5), the shell cover (2) is arranged on the opening end of the shell (1), a feeding port (18) is arranged on the shell cover (2), the panel (3) is arranged on the surface of the feeding port (18), a plurality of clamping grooves (4) are arranged on the panel (3), the dialysis bags (5) are arranged in the shell (1) and are vertically arranged opposite to the clamping grooves (4), the bag openings of the dialysis bags (5) are inserted into the clamping grooves (4) and are clamped and sealed inwardly through the clamping grooves (4), positioning columns (7) are arranged on one side of the panel (3) corresponding to the clamping grooves (4), positioning rings (6) are arranged on the two sides of the bag openings of the dialysis bags (5), the positioning rings (6) are sleeved on the positioning columns (7), and a pushing mechanism for moving the panel (3) and swinging the dialysis bags (5) is arranged on the shell cover (2).

2. The ginseng polypeptide separation and purification device according to claim 1, characterized in that: The pushing mechanism comprises an electric push rod (15), a fixing base (10), a plurality of positioning rods (11), a plurality of compression springs (9) and a plurality of limiting plates (8), the limiting plates (8) are arranged in an L-shaped structure, the limiting plates (8) are arranged at the two ends of the panel (3), one end of each limiting plate (8) is arranged on the top surface of the panel (3), the fixing base (10) is arranged at one end of the shell cover (2), a plurality of positioning holes are arranged on the fixing base (10), the positioning rods (11) are arranged on the limiting plates (8) on one side through the positioning holes, the compression springs (9) are sleeved on the outer sides of the positioning rods (11), one end of each compression spring (9) is arranged on the fixing base (10), and the other end of each compression spring (9) is arranged on the limiting plate (8) on one side, and the electric push rod (15) is arranged at the other end of the shell cover (2), and the piston rod of the electric push rod (15) is fixedly connected with the limiting plate (8) on the other side.

3. The ginseng polypeptide separation and purification device according to claim 1, characterized in that: A sliding groove (14) is arranged on the surface of the shell cover (2) in the transverse direction, a sliding strip (19) is arranged on the inner side of the panel (3) opposite to the sliding groove (14), the sliding strip (19) is arranged in the sliding groove (14) in a sliding mode, and a handle (16) is arranged on the outer side of the panel (3).

4. The ginseng polypeptide separation and purification device according to claim 1, characterized in that: A liquid inlet pipe (12) is arranged on one side of the shell (1), a liquid outlet pipe (13) is arranged on the other side of the shell (1), and valves are arranged on the liquid inlet pipe (12) and the liquid outlet pipe (13).

5. The ginseng polypeptide separation and purification device according to claim 1, characterized in that: The dialysis bags (5) are arranged in a columnar structure, and human ginseng polypeptide solution is stored in the dialysis bags (5).

6. The ginseng polypeptide separation and purification device according to claim 1, characterized in that: The length and width of the panel (3) are greater than those of the feeding port (18).

7. The ginseng polypeptide separation and purification device according to claim 1, characterized in that: A base (17) is arranged on the end of the shell (1) away from the shell cover (2).

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