Drug mixing and degassing device and drug mixing and degassing kit
By using a design that coats the inner wall of the drug mixing device with hydrophobic and hydrophilic materials, air bubbles are peeled off and stored by utilizing hydraulic differential and friction, thus solving the problem of difficult removal of air bubbles in the drug solution and achieving safe and efficient drug injection.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- AIMEICHUANG MEDICAL TECH (ZHUHAI) CO LTD
- Filing Date
- 2025-03-12
- Publication Date
- 2026-05-26
AI Technical Summary
Existing technologies are insufficient to effectively remove air bubbles from the medication, which can affect the effectiveness of the injection and pose risks to human health.
A device for removing air bubbles from a drug solution is designed. The inner wall is coated with hydrophobic and hydrophilic materials. The device uses hydraulic pressure and friction to separate air bubbles from the drug solution and store them in the air bubble storage space, preventing air bubbles from re-mixing into the drug solution.
It effectively removes air bubbles from the medication solution, reduces the risk to patients, ensures the efficacy of the medication, expands the scope of application, and reduces production and usage costs.
Smart Images

Figure CN224270938U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of medical biochemical drug mixing technology, specifically to a drug mixing and degassing device, and a drug mixing and degassing kit equipped with the drug mixing and degassing device. Background Technology
[0002] Many commercially available medications require mixing before use. However, because most medications have a certain concentration, mixing often produces numerous air bubbles. Removing these bubbles is an extremely difficult problem, and often not all bubbles can be completely eliminated. Furthermore, when medications containing air bubbles are injected into the body, it not only affects the injection's effectiveness but can also have adverse effects on health, potentially causing discomfort to the patient. Summary of the Invention
[0003] To address the aforementioned problems, the main objective of this invention is to provide a drug mixing and degassing device for removing air bubbles from a liquid medicine.
[0004] Another objective of this invention is to provide a drug mixing and degassing kit equipped with the aforementioned drug mixing and degassing device.
[0005] To achieve the main objective of this utility model, it provides a drug mixing and degassing device, comprising an injection cylinder, a piston rod, and a dispensing tube. The injection cylinder has a storage chamber with an opening at its end. The first inner wall surface of the storage chamber is a first hydrophobic surface. The piston rod passes through the opening into the storage chamber and is sealed to the first inner wall surface. The dispensing tube is sealed and installed at the front end of the injection cylinder. The dispensing tube has a dispensing channel that extends through itself and communicates with the storage chamber. The second inner wall surface of the dispensing channel is a first hydrophilic surface. The portion of the dispensing tube extending into the storage chamber forms a bubble storage space between itself and the storage chamber.
[0006] As can be seen from the above, since the first inner wall surface of the liquid storage cavity is a first hydrophobic surface, when the liquid flows through the first inner wall surface, the low surface tension and large wetting angle of the first inner wall surface cause air bubbles to tend to adhere to the first inner wall surface. Simultaneously, since the water pressure at the first inner wall surface is close to zero, while hydraulic pressure exists in the liquid area far from the first inner wall surface, this hydraulic pressure difference causes the air bubbles to be squeezed and adhered to the first inner wall surface, thus achieving the removal of air bubbles from the liquid. Furthermore, when the air bubbles pressed against the first inner wall surface move, they experience similar frictional forces as solids are subjected to by the first inner wall surface. The large frictional resistance, which is greater than the buoyancy of the bubble and / or the impact force of the liquid, causes the bubble to adhere firmly to the first inner wall surface. When the piston rod moves toward the bubble, it pushes the bubble to the bubble storage space for storage. Furthermore, since the second inner wall surface of the liquid outlet channel of the storage tube is the first hydrophilic surface, the surface tension of the first inner wall is large and the wetting angle is small, which in turn generates capillary action. Therefore, the liquid will automatically fill the liquid outlet channel, thereby separating the bubble from the liquid and storing it in the bubble storage space, and ensuring that the liquid flowing out through the liquid outlet tube is not mixed with bubbles.
[0007] A further proposed solution is to have the outer peripheral wall of the portion of the outlet pipe that extends into the storage cavity serve as a second hydrophobic surface.
[0008] As can be seen from the above, this design prevents bubbles from escaping from the bubble storage space through the outer wall of the outlet pipe and re-mixing into the liquid, thereby improving the effect of removing bubbles from the liquid.
[0009] A further proposed solution is to have an eave formed on the outer periphery of the end of the outlet tube located inside the storage cavity. The side of the eave facing the opening is the second hydrophilic surface, and the outer peripheral wall of the eave and the side of the eave facing the front end of the injection cylinder are the third hydrophobic surface.
[0010] As can be seen from the above, this design can improve the effect of the liquid being discharged smoothly through the outlet pipe and the effect of removing air bubbles from the liquid, so as to prevent air bubbles from escaping from the air bubble storage space through the outer peripheral wall of the eaves and re-mixing into the liquid.
[0011] A further proposed solution is to have a recessed groove formed at the bottom of the liquid storage chamber towards the front end of the syringe; and to have a ring formed on the outer periphery of the liquid outlet tube, which is sealed and installed in the recessed groove, with the side of the ring facing the opening being the fourth hydrophobic surface.
[0012] As can be seen from the above, this design helps to improve the reliability and strength of the connection between the dispensing pipe and the syringe, enhance the pressure-bearing capacity of the dispensing pipe, and ensure the sealing of the connection between the dispensing pipe and the syringe. In addition, the above design also makes the production and processing of the drug mixing and degassing device more convenient.
[0013] A further proposed solution is that the first, second, third, and fourth hydrophobic surfaces are all coated with hydrophobic materials; the first and second hydrophilic surfaces are both coated with hydrophilic materials; and the ring is welded to the recessed groove or bonded to the recessed groove.
[0014] As can be seen from the above, the use of hydrophobic materials to form the first, second, third, and fourth hydrophobic surfaces, and the use of hydrophilic materials to form the first and second hydrophilic surfaces, makes the production and processing of the drug mixing and degassing device more convenient and helps to reduce production costs and production difficulty.
[0015] A further embodiment is that the piston rod includes a piston head and a push rod. The piston head is sealed to the first inner wall surface. The side of the piston head facing the liquid outlet pipe has a recessed relief groove. The liquid outlet pipe can be inserted into the relief groove. The first end of the push rod is connected to the piston head.
[0016] A further improvement is that the outer periphery of the syringe is formed with a first force-receiving ear at the opening; the second end of the piston rod is formed with a force-receiving plate, and the side of the force-receiving plate facing away from the piston head is formed with an anti-slip structure; when the liquid outlet tube is inserted into the clearance groove, there is a liquid flow channel between the liquid outlet tube and the clearance groove, and the liquid flow channel is connected to the liquid outlet channel.
[0017] As can be seen from the above, the design makes it easier for staff to push the liquid in the syringe into the outlet channel of the outlet tube, and then discharge the liquid from the reservoir. The design of the flow channel helps to better drain the liquid in the syringe, thereby avoiding waste, improving the treatment effect and reducing the treatment cost.
[0018] To achieve another objective of this utility model, this utility model provides a drug mixing and degassing kit, which includes the aforementioned drug mixing and degassing device and an adapter. The first end of the adapter is sealed and connected to the connection part of the liquid outlet tube located outside the syringe.
[0019] As can be seen from the above, the drug mixing and degassing kit, by incorporating the aforementioned drug mixing and degassing device, can remove air bubbles mixed in the medication solution, thereby reducing the medication risk for patients and ensuring the medication effect; the adapter allows the drug mixing and degassing device to be connected with different types of syringes, thus expanding the applicability of the drug mixing and degassing kit and improving its practicality.
[0020] A further solution is to have a second force-bearing lug formed on the outer periphery of the adapter.
[0021] As can be seen from the above, the second force-bearing ear on the adapter facilitates the disassembly and assembly of the adapter with the drug mixing and degassing device and the syringe by the staff.
[0022] A further option is that the drug mixing and degassing kit also includes a syringe, which can be sealed and mated with the second end and / or connection of the adapter.
[0023] As can be seen above, the dispensing tube can be configured to connect directly to the syringe, making the use of the drug mixing and degassing device more convenient and reducing operating costs. Attached Figure Description
[0024] Figure 1 This is a structural diagram of the first embodiment of the drug mixing and degassing kit of this utility model.
[0025] Figure 2 This is a cross-sectional view of the drug mixing and degassing device of the first embodiment of the drug mixing and degassing kit of this utility model.
[0026] Figure 3 This is a structural diagram of the outlet pipe from a first-view perspective of the first embodiment of the drug mixing and degassing kit of this utility model.
[0027] Figure 4 This is a structural diagram of the outlet pipe from a second perspective of the first embodiment of the drug mixing and degassing kit of this utility model.
[0028] Figure 5 This is a partial structural cross-sectional view of the first embodiment of the drug mixing and degassing kit of this utility model.
[0029] Figure 6 This is a structural diagram of the adapter of the first embodiment of the drug mixing and degassing kit of this utility model.
[0030] Figure 7 This is a cross-sectional view of a partial structure of the drug mixing and degassing device in the second embodiment of the present invention.
[0031] The present invention will be further described below with reference to the accompanying drawings and embodiments. Detailed Implementation
[0032] First embodiment of the mixed medicine degassing kit
[0033] Reference Figure 1 The drug mixing and degassing kit 100 includes a drug mixing and degassing device 101, an adapter 102, and a syringe 103. The drug mixing and degassing device 101 includes a syringe barrel 1, a piston rod 2, and a dispensing tube 3.
[0034] Combination Figure 2 The syringe 1 has a liquid storage chamber 11 for storing the drug solution; the liquid storage chamber 11 has an opening 111 at the end of the syringe 1 for the piston rod 2 to be inserted into the liquid storage chamber 11. The first inner wall surface of the liquid storage chamber 11 is a first hydrophobic surface 112.
[0035] The piston rod 2 enters the liquid storage chamber 11 through the opening 111. The piston rod 2 includes a piston head 21 and a push rod 22. The piston head 21 is sealed to the first inner wall surface so that the piston rod 2 can push the liquid medicine in the liquid storage chamber 11 out of the liquid storage chamber 11. The first end of the push rod 22 is connected to the piston head 21 and is used to drive the piston head 21 to move within the liquid storage chamber 11. Preferably, the outer periphery of the syringe 1 has a first force-receiving ear 13 formed at the opening 111, and the second end of the piston rod 2 has a force-receiving plate 221 formed. This design makes it easier for the operator to push the liquid medicine in the syringe 1 towards the outlet flow channel 31 of the outlet pipe 3, and then discharge the liquid medicine from the liquid storage chamber 11. Furthermore, the side of the force-receiving plate 221 facing away from the piston head 21 has an anti-slip structure formed.
[0036] Combination Figures 3 to 5 The outlet pipe 3 is sealed and installed at the front end of the syringe 1. The outlet pipe 3 has an outlet channel 31 that extends through the outlet pipe 3 and is connected to the storage chamber 11. The second inner wall surface of the outlet channel 31 is the first hydrophilic surface 311, and the portion of the outlet pipe 3 that extends into the storage chamber 11 forms a bubble storage space 10 between the outlet pipe 3 and the storage chamber 11.
[0037] Preferably, the outer peripheral wall of the portion of the outlet pipe 3 that extends into the storage chamber 11 is a second hydrophobic surface 32, to prevent air bubbles from escaping from the air bubble storage space 10 through the outer peripheral wall of the outlet pipe 3 and re-mixing into the liquid, thereby improving the effect of removing air bubbles from the liquid.
[0038] Furthermore, the outer periphery of the end of the outlet pipe 3 located within the storage chamber 11 is formed with an eave 33; wherein, the side of the eave 33 facing the opening 111 is a second hydrophilic surface 331, while the outer peripheral wall of the eave 33 and the side of the eave 33 facing the front end of the syringe 1 are third hydrophobic surfaces 332. This design can improve the effect of the drug solution smoothly passing through the outlet pipe 3 and the effect of removing air bubbles from the drug solution, so as to prevent air bubbles from escaping from the air bubble storage space 10 via the outer peripheral wall of the eave 33 and re-mixing into the drug solution. In addition, when the liquid medicine is sent into the storage chamber 11 from the outlet tube 3 (e.g., the syringe 103 sends the liquid medicine into the storage chamber 11 through the outlet tube 3 via the adapter 102, or the syringe 103 sends the liquid medicine directly into the storage chamber 11 through the outlet tube 3), due to the high tension and small wetting angle of the second hydrophilic surface 331, a water film O will quickly form between the second hydrophilic surface 331 and the first inner wall surface, thereby preventing the bubbles in the bubble storage space 10 from escaping.
[0039] To improve the reliability and strength of the connection between the outlet tube 3 and the syringe 1, enhance the pressure-bearing capacity of the outlet tube 3, and ensure the sealing of the connection between the outlet tube 3 and the syringe 1, a recessed groove 12 is formed at the bottom of the storage chamber 11 towards the front end of the syringe 1, and a ring 34 is formed on the outer periphery of the outlet tube 3. When the outlet tube 3 is installed on the syringe 1, the ring 34 is sealed and installed in the recessed groove 12. The recessed groove 12 can support the outlet tube 3 through the ring 34, preventing the outlet tube 3 from detaching from the syringe 1 under the liquid pressure in the storage chamber 11. In addition, this design makes the production and processing of the drug mixing and degassing device 101 more convenient. Preferably, the side of the ring 34 facing the opening 111 is a fourth hydrophobic surface 341 to improve the adsorption effect of bubbles and reduce the risk of bubbles escaping from the bubble storage space 10 and re-mixing into the drug solution. The ring 34 and the recessed groove 12 can be fixed by welding (such as ultrasonic welding), or the ring 34 and the recessed groove 12 can be fixed by adhesive.
[0040] To facilitate the production and processing of the drug mixing and degassing device 101 and reduce its production cost and difficulty, the first hydrophobic surface 112, the second hydrophobic surface 32, the third hydrophobic surface 332, and the fourth hydrophobic surface 341 are all coated with hydrophobic materials. This can be understood as the first hydrophobic surface 112, the second hydrophobic surface 32, the third hydrophobic surface 332, and the fourth hydrophobic surface 341 being hydrophobic coatings. The first hydrophilic surface 311 and the second hydrophilic surface 331 are both coated with hydrophilic materials. This can be understood as the first hydrophilic surface 311 and the second hydrophilic surface 331 being hydrophilic coatings.
[0041] In this embodiment, the piston head 21 of the piston rod 2 has a recessed relief groove 211 on the side facing the liquid outlet pipe 3. When the piston rod 2 moves to the liquid outlet pipe 3, the liquid outlet pipe 3 can be inserted into the relief groove 211 and sealed with the relief groove 211, thereby sealing the bubble storage space 10 and preventing the bubbles from being forced into the liquid outlet channel 31 of the liquid outlet pipe 3, causing the bubbles to mix with the liquid medicine a second time.
[0042] Combination Figure 6The adapter 102 has a liquid flow channel 1021. The first end of the adapter 102 is sealed and connected to the connection part of the outlet tube 3 located outside the syringe 1, and the liquid flow channel 1021 is connected to the outlet flow channel 31. The second end of the adapter 102 can be sealed and connected to the syringe 103, which is used to inject the liquid medicine into the reservoir 11 through the adapter 102 and the outlet tube 3. Of course, as another optional design, the syringe 103 can also be directly sealed and connected to the connection part of the outlet tube 3 located outside the syringe 1. In this case, having the connection part of the outlet tube 3 located outside the syringe 1 allows the liquid in the reservoir 11 to flow out of the reservoir 11 better through the outlet flow channel 31. Setting the outlet tube 3 to be directly connected to the syringe 103 makes the use of the drug mixing and degassing device 101 more convenient and helps to reduce the cost of use.
[0043] Preferably, the adapter 102 has a second force-bearing ear 1022 formed on its outer periphery to facilitate the assembly and disassembly of the adapter 102 with the drug mixing and degassing device 101 and the syringe 103. The adapter 102 allows the drug mixing and degassing device 101 to be connected with different types of syringes 103, thereby expanding the applicability of the drug mixing and degassing kit 100 and improving its practicality.
[0044] In summary, because the first inner wall surface of the liquid storage chamber 11 of the mixing and venting device is a first hydrophobic surface 112, when the liquid flows through the first inner wall surface, the low surface tension and large wetting angle of the first inner wall surface cause air bubbles to tend to adhere to it. Simultaneously, since the water pressure at the first inner wall surface is close to zero, while hydraulic pressure exists in the liquid area away from the first inner wall surface, this hydraulic pressure difference causes the air bubbles to be squeezed and adhered to the first inner wall surface, thus achieving the removal of air bubbles from the liquid. Furthermore, when the air bubbles pressed against the first inner wall surface move, they experience significant frictional resistance, similar to the frictional force exerted on a solid by the first inner wall surface. This frictional resistance is greater than the buoyancy of the air bubbles and / or the... Due to the impact of the liquid medication, the bubbles adhere firmly to the first inner wall surface. When the piston rod 2 moves towards the bubbles, it pushes them to the bubble storage space 10 for storage. Furthermore, since the second inner wall surface of the liquid outlet channel 31 of the storage tube is the first hydrophilic surface 311, the surface tension of the first inner wall is high and the wetting angle is small, resulting in capillary action. Therefore, the liquid medication automatically fills the liquid outlet channel 31. With the assistance of the second hydrophobic surface 32, the third hydrophobic surface 332, the fourth hydrophobic surface 341, and the second hydrophilic surface 331, the bubbles are reliably removed from the liquid medication and stored in the bubble storage space 10, ensuring that the liquid medication flowing out through the outlet pipe 3 is free of bubbles. The drug mixing and degassing kit 100, by setting the above-mentioned drug mixing and degassing device 101, can remove bubbles mixed in the liquid medication, thereby reducing the risk of medication use for patients and ensuring the effectiveness of medication.
[0045] Second embodiment of the mixed medicine degassing kit
[0046] Reference Figure 7 The difference between this embodiment and the first embodiment of the drug mixing and degassing kit is that, in this embodiment, when the liquid outlet tube 3 is inserted into the clearance groove 211, there is a liquid flow channel 212 between the liquid outlet tube 3 and the clearance groove 211. The liquid flow channel 212 is connected to the liquid outlet channel 31. By designing the liquid flow channel 212, it is beneficial to better drain the drug solution in the syringe 1, thereby avoiding drug waste, improving the treatment effect, and reducing the treatment cost. However, the drawback of this design is that, due to the presence of the liquid flow channel 212, the bubbles in the bubble storage space 10 may be compressed and flow to the liquid outlet channel 31. Therefore, the syringe 1 can be made of transparent material to allow the movement of bubbles through the bubble storage space 10, thereby preventing bubbles from flowing to the liquid outlet channel 31 and re-mixing into the drug solution, while better avoiding drug waste.
[0047] Finally, it should be emphasized that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. For those skilled in the art, the present utility model can have various changes and modifications. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.
Claims
1. A bubble-removing device for mixing chemicals, characterized by include: An injection cartridge having a liquid reservoir with an opening at the end of the injection cartridge, wherein the first inner wall surface of the liquid reservoir is a first hydrophobic surface; A piston rod, which passes through the opening into the liquid storage chamber and is sealed to the first inner wall surface; The liquid outlet tube is sealed and installed at the front end of the syringe. The liquid outlet tube has a liquid outlet channel that runs through it and is connected to the liquid storage cavity. The second inner wall surface of the liquid outlet channel is a first hydrophilic surface. The portion of the liquid outlet tube that extends into the liquid storage cavity forms an air bubble storage space with the liquid storage cavity.
2. The mixing and degassing device according to claim 1, characterized in that: The outer peripheral wall of the portion of the outlet pipe that extends into the storage cavity is a second hydrophobic surface.
3. The mixing and degassing device according to claim 2, characterized in that: The outer periphery of the end of the outlet tube located inside the liquid storage cavity is formed with an eave. The side of the eave facing the opening is a second hydrophilic surface, and the outer peripheral wall of the eave and the side of the eave facing the front end of the injection cylinder are a third hydrophobic surface.
4. The mixing and degassing device according to claim 3, characterized in that: The bottom of the liquid storage chamber is recessed into the front end of the injection cylinder, forming a recessed groove. The outer periphery of the outlet pipe is formed with a ring portion, which is sealed and installed in the recessed groove. The side of the ring portion facing the opening is a fourth hydrophobic surface.
5. The mixing and degassing device according to claim 4, characterized in that: The first hydrophobic surface, the second hydrophobic surface, the third hydrophobic surface, and the fourth hydrophobic surface are all formed by coating with a hydrophobic material; Both the first hydrophilic surface and the second hydrophilic surface are formed by coating with a hydrophilic material; The ring portion is welded and fixed to the recessed groove, or The ring portion is bonded and fixed to the recessed groove.
6. The mixing and degassing device according to any one of claims 1 to 5, characterized in that: The piston rod includes: A piston head is sealed to the first inner wall surface. The side of the piston head facing the liquid outlet pipe has a recessed relief groove, and the liquid outlet pipe can be inserted into the relief groove. A push rod, the first end of which is connected to the piston head.
7. The mixing and degassing device according to claim 6, characterized in that: The outer periphery of the injection cylinder is formed with a first force-receiving ear at the opening, and the second end of the piston rod is formed with a force-receiving plate. The side of the force-receiving plate facing away from the piston head is formed with an anti-slip structure. When the liquid outlet pipe is inserted into the clearance groove, there is a liquid flow channel between the liquid outlet pipe and the clearance groove, and the liquid flow channel is connected to the liquid outlet channel.
8. A bubble-removing mixing kit, characterized by include: The drug mixing and degassing device as described in any one of claims 1 to 7; An adapter, the first end of which is sealed and connected to the connection part of the liquid outlet tube located outside the syringe.
9. The drug mixing and degassing kit according to claim 8, characterized in that: The adapter has a second force-bearing lug formed on its outer periphery.
10. The drug mixing and degassing kit according to claim 8 or 9, characterized in that: The drug mixing and degassing kit also includes a syringe, which can be sealed and connected to the second end of the adapter and / or the connecting part.