A pharmaceutical experimental dissolution apparatus

Abstract

This utility model belongs to the field of pharmaceutical experimental dissolution technology, specifically a pharmaceutical experimental dissolution device, including a base plate; a fixed column is fixedly connected to the middle of the base plate; a rotating column is provided at the top of the fixed column, and the rotating column is rotated by an adjustment mechanism; a placement cylinder and a cleaning tank are fixedly connected to the base plate, and the center positions of the placement cylinder and the cleaning tank are symmetrically distributed about the fixed column; an inlet pipe and an outlet pipe are provided on the cleaning tank, with the outlet pipe located below the inlet pipe; a fixed plate is fixedly connected to the top of the rotating column, and a stirring mechanism is provided on the fixed plate; a fixing mechanism is provided inside the placement cylinder; this utility model provides a pharmaceutical experimental dissolution device to solve the problem of inconvenient cleaning of existing stirring components.

Description

Technical Field

[0001] This utility model belongs to the field of pharmaceutical experimental dissolution technology, specifically a pharmaceutical experimental dissolution device. Background Technology

[0002] Pharmaceutical experimental dissolution apparatus is a specialized device used for experimental operations such as drug dissolution, dissolution analysis and solution preparation. Its core functions are to accelerate the dissolution process, control reaction conditions and quantify dissolution performance.

[0003] In existing technologies, after the drug is stirred and dissolved, drug liquid remains on the stirring element. However, existing devices are inconvenient to clean and require disassembly and cleaning, which is cumbersome and affects the overall dissolution efficiency.

[0004] Therefore, this utility model provides a pharmaceutical experimental dissolution device. Utility Model Content

[0005] In order to overcome the shortcomings of the existing technology and solve the problems raised in the background art.

[0006] The technical solution adopted by this utility model to solve its technical problem is as follows: A pharmaceutical experimental dissolution device of this utility model includes a base plate; a fixed column is fixedly connected to the middle of the base plate; a rotating column is provided at the top of the fixed column, and the rotating column rotates through an adjustment mechanism; a placement cylinder and a cleaning tank are fixedly connected to the base plate, and the center positions of the placement cylinder and the cleaning tank are symmetrically distributed about the fixed column; an inlet pipe and an outlet pipe are provided on the cleaning tank, and the outlet pipe is located below the inlet pipe; a fixed plate is fixedly connected to the top of the rotating column, and a stirring mechanism is provided on the fixed plate; a fixing mechanism is provided inside the placement cylinder.

[0007] Preferably, the stirring structure includes a servo motor; a handle is fixedly connected to the fixed plate; the servo motor is fixedly connected to the fixed plate, and the output end of the servo motor is provided with a first rotating shaft; an auger plate is fixedly connected to the outer wall of the first rotating shaft.

[0008] Preferably, a set of hinge plates is hinged to the outer wall of the bottom end of the first rotating shaft.

[0009] Preferably, the adjusting mechanism includes a first square cavity; the fixed column has a first circular cavity and a first square cavity, and the first square cavity is located below the first circular cavity, and the first square cavity and the first circular cavity are interconnected; a square block is slidably connected in the first square cavity; the bottom end of the rotating column extends into the fixed column and is fixed above the square block.

[0010] Preferably, the fixing mechanism includes a first square through groove; a set of first square through grooves are provided on the outer wall of the placement cylinder; a clamping block is slidably connected in the first square through groove; an inverted L-shaped plate is fixedly connected to the outer wall of the placement cylinder, and a threaded rod is rotatably connected to the inverted L-shaped plate; a first threaded groove is provided in the clamping block, and the threaded rod is threadedly connected in the first threaded groove; the threaded rod rotates through a rotating unit.

[0011] Preferably, the rotating unit includes an annular plate; a first gear is fixedly connected to the end of the threaded rod; an annular plate is rotatably connected to the base plate, and the cross-section of the annular plate is inverted L-shaped; an annular rack is fixedly connected to the inner wall of the annular plate, and the annular rack and the first gear mesh with each other; a push rod is fixedly connected to the outer wall of the annular plate.

[0012] The beneficial effects of this utility model are as follows:

[0013] 1. The pharmaceutical experimental dissolution device of this utility model includes a cleaning tank and a placement tank. The placement tank can hold a dissolution cup and is fixed by a fixing mechanism. After the dissolution is completed by stirring by a stirring mechanism, the rotating column is rotated by an adjusting mechanism to position the stirring mechanism inside the cleaning tank. The cleaning can be performed by first introducing liquid through the inlet pipe, filling the cleaning tank completely, or by allowing liquid to flow in through the inlet pipe and out through the outlet pipe to complete the cleaning process. No disassembly is required, making cleaning simple and convenient. The stirring mechanism also rotates during cleaning to increase cleaning efficiency.

[0014] 2. The pharmaceutical experimental dissolution device of this utility model is characterized by a servo motor starting up, which in turn drives the first rotating shaft to rotate. The rotation of the first rotating shaft drives the auger plate to rotate, allowing the liquid in the dissolution cup to tumble up and down. At the same time, when the hinge plate is placed, it can fit against the bottom of the dissolution cup, thereby breaking or pushing the solid drug and preventing it from adhering to the bottom of the dissolution cup for a long time, which would affect the dissolution efficiency. Attached Figure Description

[0015] The present invention will be further described below with reference to the accompanying drawings.

[0016] Figure 1 This is a perspective view of the present invention;

[0017] Figure 2 This is a cross-sectional view of the present invention;

[0018] Figure 3 yes Figure 2 Enlarged view of point A in the middle;

[0019] Figure 4 It is a three-dimensional diagram of the fixed mechanism;

[0020] Figure 5It is a 3D view of the fixed plate;

[0021] In the diagram: 1. Base plate; 11. Placement cylinder; 12. Cleaning tank; 13. Water inlet pipe; 14. Water outlet pipe; 15. Fixed column; 16. Rotating column; 17. Fixed plate; 2. Servo motor; 21. First rotating shaft; 22. Screwdriver plate; 23. Hinge plate; 3. First circular cavity; 31. First square cavity; 32. Square block; 4. First square through slot; 41. Clamping block; 42. Inverted L-shaped plate; 43. Threaded rod; 44. First threaded groove; 45. Annular plate; 46. Annular rack; 47. First gear; 48. Push rod. Detailed Implementation

[0022] To make the technical means, creative features, objectives and effects of this utility model easier to understand, the present utility model will be further described below in conjunction with specific embodiments.

[0023] like Figures 1 to 5 As shown, the pharmaceutical experimental dissolution device of this utility model includes a base plate 1; a fixed column 15 is fixedly connected to the middle of the base plate 1; a rotating column 16 is provided at the top of the fixed column 15, and the rotating column 16 is rotated by an adjustment mechanism; a placement cylinder 11 and a washing tank 12 are fixedly connected to the base plate 1, and the center positions of the placement cylinder 11 and the center positions of the washing tank 12 are symmetrically distributed about the fixed column 15; an inlet pipe 13 and an outlet pipe 14 are provided on the washing tank 12, and the outlet pipe 14 is located below the inlet pipe 13; a fixed plate 17 is fixedly connected to the top of the rotating column 16, and a stirring mechanism is provided on the fixed plate 17; a fixing mechanism is provided inside the placement cylinder 11; in the prior art, after the drug is stirred and dissolved, drug liquid will remain on the stirring component. However, existing devices are inconvenient to clean, requiring disassembly and cleaning operations, which are cumbersome and affect the overall dissolution efficiency. Therefore, this invention is equipped with a cleaning tank 12 and a placement tank 11 during operation. The placement tank 11 can hold the dissolution cup and is fixed by a fixing mechanism. After the dissolution is completed by stirring by the stirring mechanism, the rotating column 16 is rotated by the adjusting mechanism, so that the stirring mechanism is located in the cleaning tank 12. Liquid can be introduced for cleaning through the water inlet pipe 13, or the cleaning tank 12 can be filled for cleaning, or it can be in a flowing state, with water entering from the water inlet pipe 13 and then exiting from the water outlet pipe 14 to complete the cleaning process. No disassembly is required, making cleaning simple and convenient. In addition, the stirring mechanism is used to rotate during cleaning, increasing the cleaning efficiency.

[0024] The stirring structure includes a servo motor 2; a handle is fixedly connected to the fixed plate 17; the servo motor 2 is fixedly connected to the fixed plate 17, and the output end of the servo motor 2 is provided with a first rotating shaft 21; an auger plate 22 is fixedly connected to the outer wall of the first rotating shaft 21.

[0025] A set of hinge plates 23 are hinged to the outer wall of the bottom end of the first rotating shaft 21;

[0026] During operation, the servo motor 2 starts, which in turn drives the first rotating shaft 21 to rotate. The rotation of the first rotating shaft 21 drives the auger plate 22 to rotate, allowing the liquid in the dissolving cup to tumble up and down. At the same time, when the hinge plate 23 is placed, it can fit against the bottom of the dissolving cup, which can break or push the solid drug, preventing it from sticking to the bottom of the dissolving cup for a long time and affecting the dissolving efficiency.

[0027] The adjustment mechanism includes a first square cavity 31; the fixed column 15 has a first circular cavity 3 and a first square cavity 31, with the first square cavity 31 located below the first circular cavity 3, and the first square cavity 31 and the first circular cavity 3 are interconnected; a square block 32 is slidably connected in the first square cavity 31; the bottom end of the rotating column 16 extends into the fixed column 15 and is fixed above the square block 32; during operation, after stirring, the rotating column 16 is moved upward by the handle, allowing the square block 32 to detach from the first square cavity and enter the first circular cavity 3, thereby causing the square block 32 to rotate, so that the first rotating shaft 21 is located directly above the cleaning tank 12, and then the rotating column 16 and the square block 32 are lowered, allowing the square block 32 to enter the first square cavity, thereby allowing the auger plate 22 and the hinge plate 23 to be located in the cleaning tank 12, thus completing the cleaning operation.

[0028] The fixing mechanism includes a first square through groove 4; a set of first square through grooves 4 are provided on the outer wall of the placement cylinder 11; a clamping block 41 is slidably connected in the first square through groove 4; an inverted L-shaped plate 42 is fixedly connected to the outer wall of the placement cylinder 11, and a threaded rod 43 is rotatably connected to the inverted L-shaped plate 42; a first threaded groove 44 is provided in the clamping block 41, and the threaded rod 43 is threadedly connected in the first threaded groove 44; the threaded rod 43 rotates through a rotating unit.

[0029] The rotating unit includes an annular plate 45; a first gear 47 is fixedly connected to the end of the threaded rod 43; the annular plate 45 is rotatably connected to the base plate 1, and the cross section of the annular plate 45 is inverted L-shaped; an annular rack 46 is fixedly connected to the inner wall of the annular plate 45, and the annular rack 46 and the first gear 47 mesh with each other; a push rod 48 is fixedly connected to the outer wall of the annular plate 45.

[0030] During operation, the existing dissolving cup is placed in the placement cylinder 11. Then, the annular plate 45 is rotated by the push rod 48, which in turn drives the annular rack 46 and the first gear 47 to rotate. This drives the threaded rod 43 to rotate, which in turn drives the clamping block 41 to move. The clamping block 41 is square and can only move left and right within the first square through groove 4. The rotation of the threaded rod 43 can drive the clamping block 41 to move. The clamping block 41 moves towards the center point of the placement cylinder 11, thus clamping the dissolving cup and aligning the center point of the dissolving cup with the center point of the placement cylinder 11. This ensures the placement of the stirring mechanism. The clamping block 41 will not detach from the first square through groove 4. A slider groove can be provided, but this is not described in the prior art.

[0031] Working principle: The system includes a cleaning tank 12 and a placement tank 11. The placement tank 11 holds a dissolving cup, which is fixed by a fixing mechanism. After dissolving by stirring, the rotating column 16 is rotated by an adjusting mechanism, positioning the stirring mechanism inside the cleaning tank 12. Liquid can be introduced through the inlet pipe 13 for cleaning, either filling the tank completely or allowing it to flow through the inlet pipe 13 and outlet pipe 14. No disassembly is required, making cleaning simple and convenient. The stirring mechanism also increases cleaning efficiency. The servo motor 2 starts, driving the first rotating shaft 21 to rotate. Rotating the screw conveyor 21 will cause the screw conveyor 22 to rotate, allowing the liquid in the dissolving cup to tumble up and down. At the same time, when the hinge plate 23 is placed, it can fit against the bottom of the dissolving cup, thus breaking up or pushing the solid drug, preventing it from sticking to the bottom of the dissolving cup for a long time and affecting the dissolution efficiency. After stirring, the handle drives the rotating column 16 to move upward, allowing the square block 32 to detach from the first square cavity and enter the first circular cavity 3, thereby causing the square block 32 to rotate, so that the first rotating shaft 21 is directly above the cleaning tank 12. Then, the rotating column 16 and the square block 32 are lowered, allowing the square block 32 to enter the first square cavity, and then the screw conveyor 22 and the hinge plate 23 are placed in the cleaning tank 12, thus completing the cleaning operation.

[0032] The terms "front," "back," "left," "right," "top," and "bottom" all refer to the figures in the accompanying drawings. Figure 1 Based on the perspective of the observer, the side of the device facing the observer is defined as the front, the left side of the observer is defined as the left, and so on.

[0033] In the description of this utility model, it should be understood that the terms "center", "longitudinal", "lateral", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limiting the scope of protection of this utility model.

[0034] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A pharmaceutical experimental dissolution apparatus, characterized in that, The device includes a base plate; a fixed column is fixedly connected to the middle of the base plate; a rotating column is provided at the top of the fixed column, and the rotating column rotates through an adjustment mechanism; a placement cylinder and a cleaning bucket are fixedly connected to the base plate, and the center positions of the placement cylinder and the cleaning bucket are symmetrically distributed about the fixed column; an inlet pipe and an outlet pipe are provided on the cleaning bucket, with the outlet pipe located below the inlet pipe; a fixed plate is fixedly connected to the top of the rotating column, and a stirring mechanism is provided on the fixed plate; a fixing mechanism is provided inside the placement cylinder.

2. The pharmaceutical experimental dissolution apparatus according to claim 1, characterized in that, The stirring mechanism includes a servo motor; a handle is fixedly connected to the fixed plate; the servo motor is fixedly connected to the fixed plate, and the output end of the servo motor is provided with a first rotating shaft; an auger plate is fixedly connected to the outer wall of the first rotating shaft.

3. The pharmaceutical experimental dissolution apparatus according to claim 2, characterized in that, A set of hinge plates is hinged to the outer wall of the bottom end of the first rotating shaft.

4. The pharmaceutical experimental dissolution apparatus according to claim 3, characterized in that, The adjustment mechanism includes a first square cavity; the fixed column has a first circular cavity and a first square cavity, with the first square cavity located below the first circular cavity and the first square cavity and the first circular cavity communicating with each other; a square block is slidably connected in the first square cavity; the bottom end of the rotating column extends into the fixed column and is fixed above the square block.

5. A pharmaceutical experimental dissolution apparatus according to claim 4, characterized in that, The fixing mechanism includes a first square through groove; a set of first square through grooves are opened on the outer wall of the placement cylinder; a clamping block is slidably connected in the first square through groove; an inverted L-shaped plate is fixedly connected to the outer wall of the placement cylinder, and a threaded rod is rotatably connected to the inverted L-shaped plate; a first threaded groove is opened in the clamping block, and the threaded rod is threadedly connected in the first threaded groove; the threaded rod rotates through a rotating unit.

6. The pharmaceutical experimental dissolution apparatus according to claim 5, characterized in that, The rotating unit includes an annular plate; a first gear is fixedly connected to the end of the threaded rod; an annular plate is rotatably connected to the base plate, and the cross-section of the annular plate is inverted L-shaped; an annular rack is fixedly connected to the inner wall of the annular plate, and the annular rack and the first gear mesh with each other; a push rod is fixedly connected to the outer wall of the annular plate.

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