A high-efficiency drug liquid concentrator
By combining a multi-stage concentration mechanism with the ultrasonic cavitation effect, and dynamically adjusting the evaporation conditions, the problems of low initial efficiency and coking in the later stage of the liquid concentrate are solved, achieving efficient and stable liquid concentration.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- GUANGDONG SINOTAU PHARMA CO LTD
- Filing Date
- 2025-07-02
- Publication Date
- 2026-06-02
Smart Images

Figure CN224307818U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of pharmaceutical liquid concentrator technology, specifically a pharmaceutical liquid concentrator with high concentration efficiency. Background Technology
[0002] A pharmaceutical concentrate concentrator is a device used to remove some or all of the solvent from a pharmaceutical solution, thereby increasing the solute concentration. It operates based on the principles of heat exchange and mass transfer. By heating the solution to vaporize the solvent, and simultaneously outputting the vaporized solvent vapor, the concentration of the pharmaceutical solution is achieved. It has wide applications in the pharmaceutical, food, and chemical industries.
[0003] For example, the authorized patent with announcement number CN215195463U (a kind of drug liquid concentrator) includes a loading container, which is a hollow structure. The upper end of the loading container is movably connected to a container cover. An air inlet pipe and an air outlet pipe are fixedly connected to the left side of the outside of the loading container, and both the air inlet pipe and the air outlet pipe penetrate into the inside of the loading container. A regulating valve is fixedly installed on the outside of both the air inlet pipe and the air outlet pipe.
[0004] While the existing technologies mentioned above can clean the internal components, they lack a multi-stage concentration structure. Consequently, they cannot dynamically adjust the evaporation conditions according to different concentration stages during the concentration of the liquid, resulting in low initial evaporation efficiency and easy coking and carbonization of the high-concentration liquid in the later stages, making them impractical. Therefore, there is an urgent need in the market to develop a liquid concentrator with high concentration efficiency to help people solve the existing problems. Utility Model Content
[0005] The purpose of this invention is to provide a highly efficient liquid concentrater to solve the problems mentioned in the background art, such as the inability to dynamically adjust evaporation conditions according to different concentration stages during liquid concentration, resulting in low initial evaporation efficiency and easy coking and carbonization of high-concentration liquid in the later stage, leading to poor practicality.
[0006] To achieve the above objectives, this utility model provides the following technical solution: a high-efficiency pharmaceutical liquid concentrator, comprising a mounting base plate, above which is arranged a multi-stage concentration mechanism, including a primary concentration tank, an intermediate concentration tank, and a high-stage concentration tank, arranged sequentially from top to bottom with identical internal structures; the primary concentration tank has a concentration chamber inside, and heating chambers are symmetrically arranged on both sides below the concentration chamber inside the primary concentration tank; an electric heating tube is fixedly installed inside the heating chamber of the primary concentration tank; an equipment box is fixedly installed on one side of the primary concentration tank; a partition is fixedly installed inside the equipment box; a vacuum pump is fixedly installed above the partition; an extraction pipe is installed above the vacuum pump, one end of which extends into the concentration chamber of the primary concentration tank; a pressure sensor and a temperature sensor are fixedly installed above the primary concentration tank.
[0007] Preferably, ultrasonic transducers are symmetrically fixedly installed on both sides of the upper part of the concentration chamber inside the primary concentration box, an ultrasonic generator is fixedly installed inside the equipment box, the ultrasonic generator is electrically connected to the ultrasonic transducer, an intelligent processor is fixedly installed inside the equipment box along the upper part of the ultrasonic generator, and a breathable mesh is fixedly installed on the upper part of one side of the equipment box.
[0008] Preferably, agitation components are symmetrically arranged on both sides of the concentration chamber inside the primary concentration tank. The agitation components include agitation rods and blades. Two blades are provided and fixedly installed on the outside of the agitation rods. The agitation rods are rotatably connected to the primary concentration tank.
[0009] Preferably, motor slots are symmetrically arranged on both sides below the primary concentration tank, and an electric motor is fixedly installed inside the motor slot of the primary concentration tank. The output end of the electric motor is fixedly connected to the stirring rod.
[0010] Preferably, an insulation pad is fixedly installed on the outer side of the heating chamber inside the primary concentration box, and a temperature-conducting arc plate is fixedly installed between the concentration chamber and the heating chamber of the primary concentration box.
[0011] Preferably, an electric valve is fixedly installed below both the primary concentration tank and the intermediate concentration tank, and a conveying pipe is fixedly installed below each of the two electric valves. The lower ends of the two conveying pipes are fixedly connected to the intermediate concentration tank and the advanced concentration tank, respectively. A feed pipe is provided above the primary concentration tank, and an output pipe is provided below the advanced concentration tank.
[0012] Preferably, support legs are fixedly installed at the four corners below the primary concentration tank, intermediate concentration tank and advanced concentration tank, and electric valve II is fixedly installed on one side above the primary concentration tank, intermediate concentration tank and advanced concentration tank, and an exhaust pipe is fixedly installed above the electric valve II.
[0013] Compared with the prior art, the beneficial effects of this utility model are:
[0014] (1) This utility model has a multi-stage concentration mechanism with a primary concentration box, an intermediate concentration box and a high-level concentration box arranged from top to bottom and having the same internal structure. When the medicine is concentrated, it can effectively improve the initial evaporation efficiency, enable the solvent to vaporize and separate quickly, and avoid the coking and carbonization phenomenon of high-concentration medicine due to local overheating or unsuitable conditions in the later stage. This multi-stage concentration adjustment concentration method not only improves the concentration efficiency and reduces energy consumption, but also retains the effective components in the medicine to the greatest extent, improves the quality and stability of the medicine concentration, and enhances the practicality of the medicine concentrator.
[0015] (2) By setting an ultrasonic transducer and an ultrasonic generator on each stage of the concentration tank, the present invention can emit ultrasonic waves to the liquid medicine to induce cavitation effect, form tiny bubbles in the liquid medicine and break them rapidly, generate a strong impact force, destroy the binding force between the solute and the solvent in the liquid medicine, accelerate the vaporization process of the solvent, and improve the concentration efficiency.
[0016] (3) By setting up a stirring component, including a stirring rod and blades, the present invention can stir the liquid during the concentration of the medicine, so that the liquid flows continuously in the concentration chamber, so that all parts of the liquid can be heated evenly, thereby improving the heat transfer efficiency, accelerating the evaporation rate of the solvent, and increasing its practicality. Attached Figure Description
[0017] Figure 1 This is a schematic diagram of the structure of a high-efficiency pharmaceutical liquid concentrator according to the present invention;
[0018] Figure 2 This is a cross-sectional view of the primary concentration chamber of this utility model;
[0019] Figure 3 This is an enlarged schematic diagram of part A of this utility model;
[0020] Figure 4 This is a cross-sectional view of the equipment box of this utility model.
[0021] In the diagram: 1. Mounting base plate; 2. Primary concentration tank; 201. Concentration chamber; 202. Heating chamber; 3. Intermediate concentration tank; 4. Advanced concentration tank; 5. Feed pipe; 6. Output pipe; 7. Equipment box; 8. Support leg; 9. Electric valve one; 10. Conveying pipe; 11. Electric valve two; 12. Exhaust pipe; 13. Pressure sensor; 14. Temperature sensor; 15. Heating element; 16. Ultrasonic transducer; 17. Agitator assembly; 1701. Agitator rod; 1702. Blade; 18. Motor; 19. Temperature-conducting arc plate; 20. Insulation pad; 21. Extraction pipe; 22. Vacuum pump; 23. Partition plate; 24. Breathable mesh; 25. Ultrasonic generator; 26. Intelligent processor. Detailed Implementation
[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.
[0023] Please see Figure 1-4 This utility model provides an embodiment of a high-efficiency pharmaceutical liquid concentrator, comprising a mounting base plate 1. A multi-stage concentration mechanism is arranged above the mounting base plate 1. The multi-stage concentration mechanism includes a primary concentration tank 2, an intermediate concentration tank 3, and a high-stage concentration tank 4. The primary concentration tank 2, intermediate concentration tank 3, and high-stage concentration tank 4 are arranged sequentially from top to bottom and have identical internal structures. The primary concentration tank 2 has a concentration chamber 201 inside. A TQC-300 concentration sensor is installed at the bottom of the concentration chamber 201 of each concentration tank. Heating elements are symmetrically arranged on both sides below the concentration chamber 201 inside the primary concentration tank 2. The heating chamber 202 of the primary concentration tank 2 is equipped with an electric heating tube 15. An equipment box 7 is fixedly installed on one side of the primary concentration tank 2. A partition 23 is fixedly installed inside the equipment box 7. A vacuum pump 22 is fixedly installed above the partition 23. An exhaust pipe 21 is installed above the vacuum pump 22. One end of the exhaust pipe 21 extends into the concentration chamber 201 of the primary concentration tank 2. A pressure sensor 13 and a temperature sensor 14 are fixedly installed on the top of the primary concentration tank 2. The temperature sensor 14 is a PT100 temperature sensor, and the pressure sensor 13 is an EJA110 pressure sensor.
[0024] The gradient design of the primary concentration tank 2, intermediate concentration tank 3, and advanced concentration tank 4, combined with independently set heating and vacuum structures, facilitates dynamic adjustment throughout the entire concentration process. In the initial stage of concentration, the primary concentration tank 2 uses moderate vacuum and temperature conditions to achieve rapid evaporation. As the concentration of the drug increases, the intermediate concentration tank 3 adjusts to lower pressure and temperature to avoid damage to the active ingredients. In the final concentration stage, the advanced concentration tank 4 uses a high vacuum environment to ensure that the high-concentration drug is concentrated at low temperature. This solves the problems of low initial evaporation efficiency and later coking and carbonization caused by the inability to dynamically adjust the concentration, ensuring the stability and quality of the drug concentration and improving the practicality of the drug concentration device.
[0025] Please see Figure 2 and Figure 4 Ultrasonic transducers 16 are symmetrically fixed on both sides of the upper part of the concentration chamber 201 inside the primary concentration box 2. An ultrasonic generator 25 is fixedly installed inside the equipment box 7. The ultrasonic generator 25 is electrically connected to the ultrasonic transducer 16. An intelligent processor 26 is fixedly installed above the ultrasonic generator 25 inside the equipment box 7. A breathable net 24 is fixedly installed on the upper side of one side of the equipment box 7.
[0026] The electrical signal generated by the ultrasonic generator 25 is transmitted to the ultrasonic transducer 16, which converts it into ultrasonic vibrations and transmits them to the liquid medicine. These vibrations can generate a cavitation effect, which can form tiny bubbles in the liquid medicine and break them rapidly, generating a strong impact force. This breaks the binding force between the solute and the solvent in the liquid medicine, accelerates the vaporization process of the solvent, thereby improving the concentration efficiency and increasing its practicality.
[0027] Please see Figure 2 The primary concentration chamber 2 has two symmetrical stirring components 17 arranged on both sides of the concentration chamber 201. The stirring components 17 include stirring rods 1701 and blades 1702. Two blades 1702 are provided and fixedly installed on the outside of stirring rods 1701. Stirring rods 1701 are rotatably connected to the primary concentration chamber 2. Motor slots are symmetrically arranged on both sides below the primary concentration chamber 2. A motor 18 is fixedly installed inside the motor slot of the primary concentration chamber 2. The motor 18 is a servo motor. The output end of the motor 18 is fixedly connected to the stirring rods 1701.
[0028] The stirring component 17 is designed to stir the liquid during concentration, allowing the liquid to flow continuously within the concentration chamber. This breaks down the temperature and concentration gradients within the liquid, ensuring that all parts of the liquid are heated evenly, improving heat transfer efficiency, and thus accelerating solvent evaporation. Furthermore, stirring helps improve the uniformity of the concentration of the concentrated liquid, preventing local concentrations from becoming too high or too low, and ensuring stable quality of the concentrated liquid.
[0029] Please see Figure 3 A heat insulation pad 20 is fixedly installed on the outside of the heating chamber 202 of the primary concentration tank 2. A temperature-conducting arc plate 19 is fixedly installed between the concentration chamber 201 and the heating chamber 202 of the primary concentration tank 2. The temperature-conducting arc plate 19 is made of die-cast aluminum alloy.
[0030] The heat insulation pad 20 can effectively reduce heat loss in the heating chamber, improve heat utilization, and reduce energy consumption. During the heating process, it can more efficiently transfer the heat generated by the heating tube 15 to the heat-conducting arc plate 19. The heat-conducting arc plate 19 is made of die-cast aluminum alloy and has good thermal conductivity. It can quickly and evenly transfer heat to the liquid medicine in the concentration chamber 201, thereby improving the concentration efficiency.
[0031] Please see Figure 1 and Figure 2 Electric valve 9 is fixedly installed below both the primary concentration tank 2 and the intermediate concentration tank 3. A conveying pipe 10 is fixedly installed below each of the two electric valves 9. The lower ends of the two conveying pipes 10 are fixedly connected to the intermediate concentration tank 3 and the advanced concentration tank 4, respectively. A feed pipe 5 is provided above the primary concentration tank 2. An electric valve is provided at the connection between the feed pipe 5 and the primary concentration tank 2. An output pipe 6 is provided below the advanced concentration tank 4. An electric valve is provided at the connection between the output pipe 6 and the advanced concentration tank 4.
[0032] The electric valve 9 enables automatic transport and feed / discharge control of the liquid medicine between different concentration tanks, improving the automation level of production. During the concentration process, when the liquid medicine in the primary concentration tank reaches a certain concentration, the electric valve 9 automatically opens, and the liquid medicine smoothly enters the intermediate concentration tank through the conveying pipe 10 for the next stage of concentration, avoiding the tediousness and errors of manual operation. The electric valves on the feed pipe 5 and the output pipe 6 can adjust the feed and discharge rates of the liquid medicine, which is beneficial to the stability and continuity of the concentration process.
[0033] Please see Figure 1 and Figure 2 Support legs 8 are fixedly installed at the four corners below the primary concentration tank 2, intermediate concentration tank 3 and advanced concentration tank 4. Electric valve 2 11 is fixedly installed on one side above the primary concentration tank 2, intermediate concentration tank 3 and advanced concentration tank 4. Exhaust pipe 12 is fixedly installed above the electric valve 2 11.
[0034] The electric valve 11 and the exhaust pipe 12 facilitate the discharge and pressure regulation of the gas in the concentration chamber 201 during the concentration process, increasing practicality.
[0035] Working Principle: During use, the liquid medicine enters the concentration chamber 201 of the primary concentration tank 2 through the feed pipe 5 above the primary concentration tank 2. In the primary concentration stage, the electric heating tube 15 in the heating chamber 202 is energized and heats up. The heat is quickly transferred to the liquid medicine in the concentration chamber 201 through the temperature-conducting arc plate 19. At the same time, the vacuum pump 22 is started, and a moderate vacuum environment is formed in the concentration chamber 201 through the suction pipe 21. The pressure sensor 13 and temperature sensor 14 monitor and feed back data in real time. Meanwhile, the ultrasonic generator 25 generates an electrical signal and transmits it to the ultrasonic transducer 16. The transducer converts it into ultrasonic waves and transmits them to the liquid medicine. The cavitation effect breaks the binding force between the solute and the solvent, accelerating the vaporization of the solvent. The motor 18 drives the stirring rod 1701 to rotate the blades 1702, so that the liquid medicine flows continuously and the heat transfer efficiency is improved. The process involves a high concentration of the drug solution in the primary concentration tank 2. After a certain period of time, the liquid reaches a certain concentration, triggering the opening of the electric valve 9 below the primary concentration tank 2. The liquid then flows through the delivery pipe 10 into the intermediate concentration tank 3. During the intermediate concentration stage, the heating and vacuum conditions are adjusted to lower pressures and temperatures to prevent the destruction of active ingredients. The ultrasonic transducer 16 and the stirring assembly 17 continue to function, further concentrating the liquid. After a certain period of time, the liquid in the intermediate concentration tank 3 reaches an even higher concentration, triggering the opening of the electric valve 9 below it. The liquid then flows into the advanced concentration tank 4. In the final concentration stage, the advanced concentration tank 4 is set to a high vacuum environment. Combined with ultrasonic waves and stirring, this ensures that the high-concentration liquid is concentrated at low temperatures, preventing coking and carbonization. This achieves efficient and stable concentration of the liquid, increasing its practicality.
[0036] It will be apparent to those skilled in the art that this invention is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this invention. Therefore, the embodiments should be considered illustrative and non-limiting in all respects, and the scope of this invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this invention. No reference numerals in the claims should be construed as limiting the scope of the claims.
Claims
1. A high-efficiency pharmaceutical liquid concentrator, comprising a mounting base plate (1), characterized in that: A multi-stage concentration mechanism is provided above the mounting base plate (1). The multi-stage concentration mechanism includes a primary concentration tank (2), an intermediate concentration tank (3), and a high-stage concentration tank (4). The primary concentration tank (2), intermediate concentration tank (3), and high-stage concentration tank (4) are arranged sequentially from top to bottom and have the same internal structure. The primary concentration tank (2) has a concentration chamber (201) inside. Heating chambers (202) are symmetrically arranged on both sides below the concentration chamber (201) inside the primary concentration tank (2). 02) An electric heating tube (15) is fixedly installed inside. An equipment box (7) is fixedly installed on one side of the primary concentration box (2). A partition (23) is fixedly installed inside the equipment box (7). A vacuum pump (22) is fixedly installed above the partition (23). An exhaust pipe (21) is installed above the vacuum pump (22). One end of the exhaust pipe (21) extends into the concentration chamber (201) of the primary concentration box (2). A pressure sensor (13) and a temperature sensor (14) are fixedly installed above the primary concentration box (2).
2. The high-efficiency pharmaceutical liquid concentrator according to claim 1, characterized in that: Ultrasonic transducers (16) are symmetrically fixed on both sides of the upper part of the concentration chamber (201) of the primary concentration box (2). An ultrasonic generator (25) is fixedly installed inside the equipment box (7). The ultrasonic generator (25) is electrically connected to the ultrasonic transducer (16). An intelligent processor (26) is fixedly installed inside the equipment box (7) above the ultrasonic generator (25). A breathable mesh (24) is fixedly installed on the upper part of one side of the equipment box (7).
3. The high-efficiency pharmaceutical liquid concentrator according to claim 1, characterized in that: The primary concentration tank (2) has two symmetrical stirring components (17) arranged on both sides of the concentration chamber (201). The stirring components (17) include a stirring rod (1701) and blades (1702). Two blades (1702) are provided and fixedly installed on the outside of the stirring rod (1701). The stirring rod (1701) is rotatably connected to the primary concentration tank (2).
4. A high-efficiency pharmaceutical liquid concentrator according to claim 3, characterized in that: The primary concentration tank (2) has motor slots symmetrically arranged on both sides below it. An electric motor (18) is fixedly installed inside the motor slot of the primary concentration tank (2). The output end of the electric motor (18) is fixedly connected to the stirring rod (1701).
5. A high-efficiency pharmaceutical liquid concentrator according to claim 1, characterized in that: A heat insulation pad (20) is fixedly installed on the outside of the heating chamber (202) of the primary concentration box (2), and a temperature-conducting arc plate (19) is fixedly installed between the concentration chamber (201) and the heating chamber (202) of the primary concentration box (2).
6. A high-efficiency pharmaceutical liquid concentrator according to claim 1, characterized in that: Electric valves (9) are fixedly installed below the primary concentration tank (2) and the intermediate concentration tank (3). Conveying pipes (10) are fixedly installed below the two electric valves (9). The lower ends of the two conveying pipes (10) are fixedly connected to the intermediate concentration tank (3) and the advanced concentration tank (4) respectively. A feed pipe (5) is provided above the primary concentration tank (2), and an output pipe (6) is provided below the advanced concentration tank (4).
7. A high-efficiency pharmaceutical liquid concentrator according to claim 1, characterized in that: Support legs (8) are fixedly installed at the four corners below the primary concentration tank (2), intermediate concentration tank (3) and advanced concentration tank (4). Electric valve two (11) is fixedly installed on one side above the primary concentration tank (2), intermediate concentration tank (3) and advanced concentration tank (4). An exhaust pipe (12) is fixedly installed above the electric valve two (11).