Combined sterile chamber

By designing a modular sterile chamber, employing a box-and-alignment combination structure and a cathode lock design, the problems of the sterile isolation operation device being unable to be used independently and the sterile environment being compromised are solved, enabling independent use and maintenance of the sterile environment, and reducing operation time and costs.

CN224308430UActive Publication Date: 2026-06-02YJ BIOTECHNOLOGYCO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
YJ BIOTECHNOLOGYCO LTD
Filing Date
2025-05-29
Publication Date
2026-06-02

AI Technical Summary

Technical Problem

Existing aseptic isolation devices cannot be used independently after being disassembled, and the aseptic environment is disrupted when mobile culture equipment is connected, resulting in increased operation time and costs.

Method used

Design a modular sterile chamber, which uses at least two chambers connected in series, each chamber having a sealed space, and the chambers are sealed together by first and second alignment structures and a cathode lock to ensure that the sterile environment is not contaminated by the outside air.

Benefits of technology

This allows for independent use of the enclosure and maintenance of a sterile environment, reducing the frequency of sterilization, improving operational efficiency, and lowering costs.

✦ Generated by Eureka AI based on patent content.

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Abstract

A combined sterile cavity includes at least two boxes, each of which has a sealed space, and two adjacent boxes are respectively provided with a first connecting door and a second connecting door which communicate the sealed space, and a first alignment combination structure and a second alignment combination structure, the first connecting door has a first outer wall surface, the second connecting door has a second outer wall surface, two boxes are locked and engaged through the first alignment combination structure and the second alignment combination structure, and the first outer wall surface and the second outer wall surface are face to face and completely fit together, so that the first connecting door and the second connecting door can be opened together to communicate the sealed spaces of two adjacent boxes; accordingly, each box can be used independently or in combination to meet different application requirements.
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Description

Technical Field

[0001] This utility model relates to a sterile cavity, and more particularly to a combined sterile cavity that can be used independently. Background Technology

[0002] Aseptic isolation operating devices, such as Taiwan Patent No. M621381, include a control cabinet, a reagent container, a pneumatic processing cabinet, and a preparation table forming a sterile preparation space. The reagent container is located on the left side of the preparation table, and a mobile culture device is located on the right side. The sterile preparation space of the preparation table is for the operator to prepare reagents or process samples. The operator performs operations within the sterile preparation space by extending at least one application kit into the space.

[0003] In this conventional equipment, the reagent container and the preparation table are designed as a single unit. Once separated, the environment is not sealed, and therefore it cannot be used independently. Consequently, whenever the reagents in the container need to be added or replenished, it must wait until the work in the aseptic preparation space is completed, which is quite time-consuming.

[0004] Furthermore, in conventional mobile culture equipment, when the preparation table is connected, the aseptic preparation space is connected to the outside space. As a result, outside air can enter the aseptic preparation space and disrupt the aseptic environment. External bacteria may contaminate the reagents or samples. In order to avoid reducing reliability, the sterilization frequency must be increased, which increases the cost of the process. Utility Model Content

[0005] The main purpose of this invention is to disclose a modular sterile cavity that can be used independently and where outside air will not enter the sterile environment.

[0006] To achieve the above objectives, this utility model discloses a combined sterile chamber, comprising at least two serially connected housings, a first alignment and connection structure, a second alignment and connection structure, and at least two cathode locks. Each housing has a sealed space, and adjacent housings are respectively provided with a first connecting door and a second connecting door communicating with the sealed space. The first connecting door has a first outer wall surface, and the second connecting door has a second outer wall surface matching the first outer wall surface. The first alignment and connection structure has two first protruding ribs, which are disposed on the housing and located on both sides of the first connecting door. Each first protruding rib is provided with at least one pair of alignment guide wheels, which are located on the first protruding rib. The second alignment and connection structure has two second protruding ribs, which are disposed on the housing and located on both sides of the second connecting door. The positions of the two first protruding ribs and the two second protruding ribs correspond to each other and can be aligned and engaged. The at least two cathode locks each have a latch and a lock body, which are respectively disposed on the contact surfaces of the two first protruding ribs and the two second protruding ribs. Each of the first protruding ribs is aligned and engaged with the second protruding rib through the at least one pair of alignment guide wheels, and is locked by inserting the latch into the lock body, so that the two box locks are engaged together, and the first outer wall surface and the second outer wall surface are face to face and completely fitted together, so that the first connecting door and the second connecting door can be opened together, and the sealed space of the two adjacent boxes can be connected.

[0007] In one embodiment of this utility model, the two first protruding ribs are respectively provided with at least one sensor to sense whether they are in contact with the corresponding housing.

[0008] In one embodiment of the present invention, a ball is provided on a sliding contact surface of the second rib that slides in contact with the first rib.

[0009] In one embodiment of this utility model, each of the boxes is provided with a hydrogen peroxide disinfection device.

[0010] In one embodiment of this utility model, each of the boxes is provided with an electron microscope.

[0011] In one embodiment of this utility model, each of the housings is provided with a fan device.

[0012] In one embodiment of the present invention, each of the boxes has a set of rollers for carrying the box to move.

[0013] In one embodiment of this utility model, the at least two connected boxes are actually three, namely an incubator, a main chamber, and a material box.

[0014] In one embodiment of this utility model, a centrifuge is installed in the sealed space of the main compartment.

[0015] In one embodiment of this utility model, there are four boxes arranged in series: one box is an incubator, two boxes are main compartments, and one box is a material box.

[0016] In one embodiment of the present invention, it further includes a plurality of experimental devices and at least one wireless connection device. At least one housing is provided for housing at least one experimental device and one wireless connection device. The wireless connection device is connected to the experimental device inside the housing, and the wireless connection device is provided for an operator to independently remotely control and monitor the experimental device via a remote operating device.

[0017] In one embodiment of the present invention, the enclosure has a central control panel, which is connected to the wireless connection device, and the central control panel is used to control the plurality of experimental devices of the enclosure.

[0018] In one embodiment of the present invention, the enclosure has an information display panel connected to the wireless connection device, and the information display panel is for displaying the operating status of the plurality of experimental devices in the enclosure.

[0019] In one embodiment of the present invention, the box has an opening communicating with the sealed space, a door closing the opening, a plurality of support frames and at least one partition plate. The sealed space has two side walls adjacent to the opening. The plurality of support frames are correspondingly arranged on the two side walls, and the plurality of support frames located on different side walls are paired to form a support structure. There is a height gap between two adjacent support structures. The at least one partition plate is selectively arranged on one of the plurality of support structures and divides the sealed space into at least one partition space.

[0020] In one embodiment of this utility model, the plurality of support frames are arranged at equal intervals on the two side walls.

[0021] In summary, each of the boxes of this utility model has an independent sealed space, allowing them to be used independently. When two adjacent boxes are used together, the first outer wall surface and the second outer wall surface are aligned face-to-face and fully fitted, and the first connecting door and the second connecting door are fixed together so that they can be opened together. Therefore, when the sealed spaces of two adjacent boxes are connected, outside air will not enter or come into contact with the sterile environment of the sealed space, thus eliminating the problem of contamination by external bacteria. Attached Figure Description

[0022] Figure 1 This is a schematic diagram of the structure of this utility model;

[0023] Figure 2A This is a schematic diagram of the connection structure of the box body of this utility model. Figure 1 ;

[0024] Figure 2B This is a schematic diagram of the connection structure of the box body of this utility model;

[0025] Figure 2C This is a schematic diagram illustrating the connection and use of the housing of this utility model. Figure 1 ;

[0026] Figure 2D This is a schematic diagram of the connection and use of the box body of this utility model;

[0027] Figure 3 This is a schematic diagram of another embodiment of the present utility model;

[0028] Figure 4 This is a schematic diagram of wireless transmission of this utility model;

[0029] Figure 5 This is a schematic diagram of the internal space partition structure of this utility model;

[0030] Figure 6 This is a schematic diagram illustrating the implementation and use of this utility model;

[0031] Figure 7 This is a schematic diagram illustrating another embodiment of the present utility model.

[0032] Figure 8 This is another schematic diagram illustrating the use of this utility model. Detailed Implementation

[0033] The detailed description and technical content of this utility model are as follows, in conjunction with the accompanying drawings:

[0034] Please see " Figure 1 " Figure 2A " Figure 2B "and" Figure 4 As shown in the figure, this utility model discloses a combined sterile cavity, including at least two serially connected boxes 10, a first alignment and connection structure 20, a second alignment and connection structure 30, at least two cathode locks 40, multiple experimental devices 50 and at least one wireless connection device 60.

[0035] Each enclosure 10 has a sealed space 11, and at least one enclosure 10 is used to house at least one experimental device 50 and a wireless connection device 60 within the sealed space 11. The wireless connection device 60 is connected to the experimental device 50 within the enclosure 10, and the wireless connection device 60 allows an operator to independently remotely control and monitor the experimental device 50 via a remote operating device 70 (e.g., Figure 4 As shown), the remote operating device 70 can be any of a mobile phone, tablet, laptop, desktop computer, etc.

[0036] In this embodiment, the plurality of experimental devices 50 are selected from the group consisting of a hydrogen peroxide sterilization device 50A, an electron microscope 50B, a centrifuge 50C, and a fan device 50D. The hydrogen peroxide sterilization device 50A provides hydrogen peroxide into the sealed space 11 for sterilization. The electron microscope 50B is used for microscopic operations. The fan device 50D blows clean laminar air to maintain a sterile and dust-free environment. Additionally, each housing 10 is provided with a set of casters 51 for easy movement of the housing 10.

[0037] In this embodiment, there are three interconnected boxes 10, namely an incubator 10A, a main chamber 10B, and a material box 10C. The centrifuge 50C is installed in the sealed space 11 of the main chamber 10, and the centrifuge 50C is used for purification operations.

[0038] Please see " Figure 1 "and" Figure 4 As shown, the enclosure 10 has a central control panel 80. Preferably, the central control panel 80 is located in the material box 10C. The central control panel 80 is connected to the wireless connection device 60, and the central control panel 80 is used to control the operation of the multiple experimental devices 50 in the enclosure 10, namely, the hydrogen peroxide sterilization device 50A, the electron microscope 50B, the centrifuge 50C, and the fan device 50D. The enclosure 10 may also have an information display panel 81. Preferably, the information display panel 81 is located in the incubator 10A. The information display panel 81 is connected to the wireless connection device 60, and the information display panel 81 is used to display the operating status of the multiple experimental devices 50 in the enclosure 10. The central control panel 80 displays the operational status of the hydrogen peroxide sterilizer 50A, electron microscope 50B, centrifuge 50C, and fan device 50D. More specifically, it can display the image of the electron microscope 50B. Accordingly, operators can wirelessly connect to the wireless connection device 60 via the remote operating device 70 to remotely control the operation of the hydrogen peroxide sterilizer 50A, electron microscope 50B, centrifuge 50C, and fan device 50D. They can also remotely obtain information from the display panel 81 to understand the operational status of the hydrogen peroxide sterilizer 50A, electron microscope 50B, centrifuge 50C, and fan device 50D.

[0039] Please also refer to " Figure 1 " Figure 2A " Figure 2B " Figure 2C "and" Figure 2DAs shown, each of the two adjacent boxes 10 is provided with a first connecting door 12 and a second connecting door 13, which respectively connect to the sealed space 11 (e.g., Figure 2C (As shown). The first connecting door 12 has a first outer wall surface 121, and the second connecting door 13 has a second outer wall surface 131, which matches the first outer wall surface 121.

[0040] The first alignment and connection structure 20 has two first protruding ribs 21, which are disposed on the housing 10 and located on both sides of the first connecting door 12. Each first protruding rib 21 is provided with at least one pair of alignment guide wheels 22, which are located on the first protruding rib 21. When there are multiple alignment guide wheels 22, the multiple alignment guide wheels 22 are evenly distributed on the first protruding rib 21 (e.g., Figure 2A As shown in the figure, an elastic element (not shown) is provided between the at least one pair of alignment guide wheels 22 and the first protruding rib 21. The elastic element allows the at least one pair of alignment guide wheels 22 to protrude slightly beyond the first protruding rib 21, and to retract into the first protruding rib 21 after the two first protruding ribs 21 and the two second protruding ribs 31 are aligned and engaged. The second alignment and engagement structure 30 has two second protruding ribs 31, which are provided on the housing 10 and located on both sides of the second connecting door 13. The positions of the two first protruding ribs 21 and the two second protruding ribs 31 correspond to each other and can be aligned and engaged.

[0041] In one embodiment, each of the two first protruding ribs 21 may be provided with at least one sensor 23, which is used to sense whether it contacts the corresponding housing 10 to ensure that the alignment and engagement are successfully completed. Furthermore, a ball bearing 32 is provided on a sliding contact surface 311 of the second protruding rib 31 that slides against the first protruding rib 21. The ball bearing 32 can assist in smoother relative sliding between the two first protruding ribs 21 and the two second protruding ribs 31, allowing for a smoother movement to the predetermined position during alignment and engagement.

[0042] The space between the two first protruding ribs 21 and the two second protruding ribs 31 is for mounting at least two cathode locks 40. Each of the at least two cathode locks 40 has a locking tongue 41 and a lock body 42, respectively disposed on the contact surfaces of the two first protruding ribs 21 and the two second protruding ribs 31. Each first protruding rib 21 is aligned and engaged with the second protruding rib 31 via at least one pair of alignment guide wheels 22, and is locked by inserting the locking tongue 41 into the lock body 42, thereby engaging the two housings 10 together. The first outer wall surface 121 and the second outer wall surface 131 are face-to-face and completely fitted together (e.g., ...). Figure 2C As shown), so that the first connecting door 12 and the second connecting door 13 can be opened together (as shown). Figure 2DAs shown), this connects the sealed spaces 11 of two adjacent boxes 10.

[0043] In one embodiment, the larger sealed space 11 is selected as the working space. If the spaces are of equal size, one is selected according to the needs. The first connecting door 12 and the second connecting door 13 open together toward the working space. That is, the opening directions of the first connecting door 12 and the second connecting door 13 are opposite to their respective housings 10, so they can open together toward the working space.

[0044] Since the first outer wall surface 121 and the second outer wall surface 131, which are exposed to the outside air, are face to face and completely fitted together, when the first connecting door 12 and the second connecting door 13 are opened together, the first outer wall surface 121 and the second outer wall surface 131 will not be exposed in the sealed space 11. Therefore, the sterile environment of the sealed space 11 will not be damaged, and there is no need to perform sterilization again.

[0045] Please also refer to " Figure 3 As shown, the at least one box 10 can be a modular design, meaning the number of incubators 10A, main chambers 10B, and material boxes 10C can be freely selected and connected in series according to actual needs. In another embodiment, there are four boxes 10 connected in series, one of which is an incubator 10A, two of which are main chambers 10B, and one of which is a material box 10C. There are two main chambers 10B, which can increase the operating space and quantity to meet specific usage requirements.

[0046] Please refer to "" Figure 5 "and" Figure 6 As shown, the box 10 has an opening 14, a door 15, multiple support frames 16 and at least one partition plate 17. The opening 14 communicates with the sealed space 11, the door 15 closes the opening 14, and the sealed space 11 has two side walls 111 adjacent to the opening 14.

[0047] The plurality of support frames 16 are correspondingly disposed on the two side walls 111. Preferably, the plurality of support frames 16 are disposed at equal intervals on the two side walls 111. The plurality of support frames 16 located on different side walls 111 are arranged in pairs to form a support structure 161, and there is a gap height 162 between adjacent support structures 161.

[0048] The at least one partition tray 17 is selectively disposed on one of the plurality of support structures 161 according to the size of the at least one specimen box 90, forming an independent pull-out drawer structure, which allows for easy insertion or removal of the at least one specimen box 90. The at least one partition tray 17 divides the sealed space 11 into at least one partition space 112, which is suitable for storing the at least one specimen box 90, allowing the at least one specimen box 90 to be classified and stored separately.

[0049] Please see " Figure 7 As shown in the diagram, this is another embodiment of the present invention. When the box 10 needs to store a specimen box 90A with a larger height (compared to "..."), Figure 6 The specimen box 90A can be divided into a smaller number of at least one partition tray 17, and the at least one partition tray 17 can be placed on the support frame 16 in a suitable position. At this time, the accommodating space 11 can be divided into a larger and more suitable partition space 112A to accommodate the specimen box 90A with a larger height dimension.

[0050] Please see " Figure 8 As shown, this is a schematic diagram of another embodiment of the present invention. When the box 10 needs to store a specimen box 90B with a larger width (compared to "..."), Figure 7 The specimen box 90A is divided into a separate space 112A, which can also be used to store the specimen box 90B with a larger width.

[0051] Therefore, this utility model is a sterile isolation operation device that can be used independently, and has the following characteristics:

[0052] 1. Each of the at least two boxes has an independent sealed space, so they can be used independently. When two adjacent boxes are used together, the first outer wall surface that comes into contact with the outside air is face to face and completely adheres to the second outer wall surface. Therefore, outside air will not enter or come into contact with the sterile environment of the sealed space, and there is no problem of contamination by external bacteria.

[0053] 2. The at least two chambers are modularly designed, allowing for flexible selection of the number of incubators, main chambers, and material boxes, which can be connected in series according to actual needs to meet different application requirements.

[0054] 3. Each of these boxes is equipped with a hydrogen peroxide sterilization device, allowing cell samples, culture media, and other specimens to be sterilized before being placed inside the box, thus reducing the waiting time required for pre-sterilization.

[0055] 4. Each of these boxes is equipped with a set of rollers, which facilitates the movement of the box and meets the needs of modular assembly and disassembly.

[0056] 5. The design of having corresponding positions and matching shapes for the at least one positioning hole and the at least one positioning post, and the at least one positioning hole and the at least one positioning post being conical, can assist the automatic positioning of the first connecting door and the second connecting door.

[0057] 6. The first and second connecting structures are joined together by matching the shape of the recess and the protrusion, which is quite intuitive to operate and has a foolproof effect.

[0058] 7. The enclosure is equipped with a wireless connection device, which allows operators to wirelessly connect to the remote control device to independently control and monitor multiple experimental devices to perform specific tasks. This meets the needs of remote operation and allows for remote monitoring of the operation status of multiple experimental devices, thereby improving the operator's work efficiency.

[0059] 8. By placing at least one partition plate on different support structures, the accommodating space is divided into partition spaces of different sizes, thereby accommodating specimen boxes of different sizes and increasing the versatility of the box.

[0060] 9. The at least one partition tray can be extracted independently, and the at least one specimen box can be classified and stored separately, making it convenient to insert or remove the at least one specimen box.

[0061] 10. The at least one specimen box is stored separately in different compartments, which can reduce the possibility of other specimen boxes being contaminated when the specimen box fails and bacteria are leaked.

Claims

1. A modular sterile cavity, characterized in that, Including: At least two boxes are connected in series, each box having a sealed space, and two adjacent boxes are respectively provided with a first connecting door and a second connecting door communicating with the sealed space. The first connecting door has a first outer wall surface, and the second connecting door has a second outer wall surface matching the first outer wall surface. A first alignment and connection structure has two first protruding ribs, which are disposed on the housing and located on both sides of the first connecting door, and each of the first protruding ribs is provided with at least one pair of alignment guide wheels, which are located on the first protruding rib. A second alignment and joining structure, the second alignment and joining structure having two second protruding ribs, the two second protruding ribs being disposed on the housing and located on both sides of the second connecting door, and the positions of the two first protruding ribs and the two second protruding ribs respectively corresponding to each other so as to be aligned and joined; and At least two cathode locks, each having a latch and a lock body, are respectively disposed on the contact surfaces of the two first ribs and the two second ribs. Each of the first ribs is aligned and engaged with the second rib through at least one pair of alignment guide wheels, and is locked by inserting the latch into the lock body, so that the two housing locks are engaged together, and the first outer wall surface and the second outer wall surface are face to face and completely fitted together, so that the first connecting door and the second connecting door can be opened together, and the sealed spaces of the two adjacent housings are connected.

2. The combined sterile cavity according to claim 1, characterized in that, Each of the two first protruding ribs is provided with at least one sensor to detect whether it is in contact with the corresponding housing.

3. The combined sterile cavity according to claim 1, characterized in that, The second rib has a ball bearing disposed on a sliding contact surface that makes contact with the first rib.

4. The combined sterile cavity according to claim 1, characterized in that, Each of these boxes is equipped with a hydrogen peroxide sterilization device.

5. The combined sterile cavity according to claim 1, characterized in that, Each of these enclosures is designed to house one electron microscope.

6. The combined sterile cavity according to claim 1, characterized in that, Each enclosure is equipped with a fan device.

7. The combined sterile cavity according to claim 1, characterized in that, Each of the boxes has a set of rollers that carry the box to move.

8. The combined sterile cavity according to claim 1, characterized in that, The at least two connected boxes are actually three separate boxes: an incubator, a main chamber, and a material box.

9. The combined sterile cavity according to claim 8, characterized in that, A centrifuge is installed in the sealed space of the main compartment.

10. The combined sterile cavity according to claim 1, characterized in that, The at least two-in-series connected boxes consist of four boxes: one box is an incubator, two boxes are main compartments, and one box is a material box.

11. The combined sterile cavity according to claim 1, characterized in that, It also includes multiple experimental devices and at least one wireless connection device. At least one enclosure is provided for housing at least one experimental device and one wireless connection device. The wireless connection device is connected to the experimental device inside the enclosure, and the wireless connection device is used by an operator to independently remotely control and monitor the experimental device via a remote operating device.

12. The combined sterile cavity according to claim 11, characterized in that, The enclosure has a central control panel that is connected to the wireless connection device and is used to control the multiple experimental devices within the enclosure.

13. The combined sterile cavity according to claim 11, characterized in that, The enclosure has an information display panel connected to the wireless connection device, and the information display panel is used to display the operating status of the multiple experimental devices in the enclosure.

14. The combined sterile cavity according to claim 1, characterized in that, The enclosure has an opening communicating with the sealed space, a door closing the opening, multiple support frames and at least one partition plate. The sealed space has two side walls adjacent to the opening. The multiple support frames are correspondingly arranged on the two side walls, and the multiple support frames located on different side walls are paired up to form a support structure. There is a height gap between two adjacent support structures. The at least one partition plate is selectively arranged on one of the multiple support structures and divides the sealed space into at least one partition space.

15. The combined sterile cavity according to claim 14, characterized in that, The multiple support frames are arranged at equal intervals on the two side walls.