High-efficiency continuous cell disruption device

Abstract

This utility model relates to the field of cell disruption device technology, specifically a high-efficiency continuous cell disruption device, including a cell disruption device body. A cell disruption component is installed at the front end of the cell disruption device body, and a telescopic cylinder is fixedly installed on the side of the cell disruption component. By placing the cell environment on the placement seat, the cells are positioned above the disruption device body. Then, a signal is transmitted from the cloud to the cell disruption device body, causing the lateral positioning end to slide on the side of the adjustment track, moving the cell disruption component to the cell placement seat position. After the anesthetized cells are disrupted, the cell disruption component controls the telescopic cylinder to drive the telescopic rod to descend, moving its end disruption device to the appropriate disruption position. The adjustment key block slides down to disrupt the internal cells. The auxiliary disruption disc stabilizes the telescopic rod, preventing shaking during disruption, thus making the whole device very stable, reliable, and flexible.

Description

Technical Field

[0001] This utility model relates to the field of cell disruption device technology, specifically a high-efficiency continuous cell disruption device. Background Technology

[0002] Cell disruption, or cell disruption technology, refers to the technique of using external force to break down cell membranes and cell walls, releasing the cell contents, including the target product. When separating and purifying a specific protein through cell disruption, the protein must first be released from the tissue or cell while maintaining its original natural state and activity. Therefore, appropriate methods must be used to disrupt the tissue and cells. This applies to tissues from different organisms or different parts of the same organism.

[0003] Currently, crushing devices are positioned and adjusted manually by turning bolts. Even after positioning is complete, the height of the crushing device still needs to be adjusted manually. The adjustment method is quite complicated. If the height positioning is incorrect, the bolts need to be loosened and repositioned, making the positioning process complicated and inconvenient.

[0004] In view of this, we propose a highly efficient continuous cell disruption device. Summary of the Invention

[0005] To overcome the above shortcomings, this invention provides a highly efficient continuous cell disruption device.

[0006] The technical solution of this utility model is:

[0007] A high-efficiency continuous cell disruption device includes a cell disruption device body, a cell disruption component installed at the front end of the cell disruption device body, a telescopic cylinder fixedly installed on the side of the cell disruption component, a telescopic rod installed at the output end of the telescopic cylinder, a positioning plate installed on the front side of the telescopic rod, an auxiliary disruption disc installed on the end side of the telescopic rod, a disruption device fixedly installed below the end of the telescopic rod, and a viewing glass plate opened on the side of the disruption device.

[0008] As a preferred technical solution, an adjustment key block is installed on the side of the viewing glass plate, and a positioning component is installed on the side of the cell disruption component.

[0009] As a preferred technical solution, the output end of the positioning component is equipped with a pneumatic connection end, and a second regulator is installed below the pneumatic connection end. The output end of the second regulator is provided with an adjusting slide rod, and a second positioning block is fixedly connected to the side of the adjusting slide rod. A movable disk is fixedly installed on the side of the second positioning block.

[0010] As a preferred technical solution, a positioning block is fixedly installed below the moving disk, an adjuster is provided on the right side of the positioning block, and the main body of the crushing device is provided below the adjuster.

[0011] As a preferred technical solution, the side of the main body of the crushing device is provided with an adjustment rail, and the side of the adjustment rail is slidably connected with a transverse positioning end.

[0012] As a preferred technical solution, an adjustment plate is installed on the side of the transverse positioning end, a connecting positioning arm is provided above the adjustment plate, and a buffer pillow is provided at the front end of the main body of the crushing device.

[0013] As a preferred technical solution, a support frame 1 is installed below the main body of the crushing device, and a support frame 2 is provided at the rear end of the support frame 1.

[0014] Compared with the prior art, the beneficial effects of this utility model are:

[0015] 1. This utility model places the cell environment on the placement seat, so that the cells are placed above the main body of the cell disruption device. Then, the cloud transmits a signal to the main body of the cell disruption device, so that the lateral positioning end slides on the side of the adjustment track, and moves the cell disruption component to the cell placement seat position. After the anesthetized cells are disrupted, the cell disruption component controls the telescopic cylinder to drive the telescopic rod to descend, so that its end disruption device moves to the appropriate disruption position. The adjustment key block slides down to disrupt the internal cells. The auxiliary disruption disc stabilizes the telescopic rod and prevents it from shaking during disruption, so that the whole device is very stable, reliable and flexible.

[0016] 2. This utility model connects two regulators, namely regulator one and regulator two, through the air pressure connection end of the positioning component. The difference in input air pressure at both ends causes the adjusting slide rod to slide inside the regulator, which drives positioning block two and positioning block one to move laterally, thereby positioning the moving disk. This can prevent the device from being inconvenient to make changes and adjustments after positioning is completed, thus improving its practicality. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the main structure of the cell disruption device of this utility model;

[0018] Figure 2 This is a schematic diagram of the external component structure of this utility model;

[0019] Figure 3 This is a schematic diagram of the cell disruption component structure of this utility model;

[0020] Figure 4 This is a schematic diagram of the positioning component structure of this utility model.

[0021] In the diagram: 1. Cell disruption device main body; 11. Connecting positioning arm; 12. Disruption device main body; 13. Buffer pillow; 14. Adjusting track; 15. Lateral positioning end; 16. Adjusting plate; 17. Support frame one; 18. Support frame two; 2. Cell disruption assembly; 21. Telescopic rod; 22. Telescopic cylinder; 23. Positioning plate; 24. Auxiliary disruption disc; 25. Viewing glass plate; 26. Adjusting key block; 27. Disruption device; 3. Positioning assembly; 31. Pneumatic connection end; 32. Moving disc; 33. Positioning block one; 34. Regulator one; 35. Positioning block two; 36. Adjusting slide bar; 37. Regulator two. Detailed Implementation

[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0023] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0024] Please see Figures 1 to 4 This utility model provides a technical solution:

[0025] A high-efficiency continuous cell disruption device includes a cell disruption device body 1, a cell disruption component 2 installed at the front end of the cell disruption device body 1, a telescopic cylinder 22 fixedly installed on the side of the cell disruption component 2, a telescopic rod 21 installed at the output end of the telescopic cylinder 22, a positioning plate 23 installed on the front side of the telescopic rod 21, an auxiliary disruption disc 24 installed on the end side of the telescopic rod 21, a disruption device 27 fixedly installed below the end of the telescopic rod 21, a viewing glass plate 25 opened on the side of the disruption device 27, an adjustment key block 26 installed on the side of the viewing glass plate 25, and a positioning component 3 installed on the side of the cell disruption component 2.

[0026] It should be added that by positioning the cell disruption component 2 to the cell placement seat, after the anesthetized cells are disrupted, the cell disruption component 2 controls the telescopic cylinder 22 to lower the telescopic rod 21, so that its end disruption device 27 moves to the appropriate disruption position. The adjusting key block 26 slides down to disrupt the internal cells, and the auxiliary disruption disc 24 stabilizes the telescopic rod 21 to prevent it from shaking during disruption, thus making the whole system very stable, reliable and flexible.

[0027] In a preferred embodiment, the output end of the positioning component 3 is equipped with a pneumatic connection end 31, and a second regulator 37 is installed below the pneumatic connection end 31. The output end of the second regulator 37 is provided with an adjusting slide rod 36. A second positioning block 35 is fixedly connected to the side of the adjusting slide rod 36. A movable disk 32 is fixedly installed on the side of the second positioning block 35. A first positioning block 33 is fixedly installed below the movable disk 32. A first regulator 34 is provided on the right side of the first positioning block 33. The main body 12 of the crushing device is provided below the first regulator 34.

[0028] It is worth noting that by connecting the two regulators 37 and 34 at both ends through the air pressure connection end 31 of the positioning component 3, the difference in input air pressure at both ends causes the adjusting slide rod 36 to slide inside the regulator, driving the positioning block 35 and 33 to move laterally, thereby positioning the moving disk 32. This prevents the device from being inconvenient to make changes and adjustments after positioning is completed, thus improving its practicality.

[0029] As a preferred embodiment, the side of the crushing device body 12 is provided with an adjustment track 14, the side of the adjustment track 14 is slidably connected with a transverse positioning end 15, the side of the transverse positioning end 15 is provided with an adjustment plate 16, the top of the adjustment plate 16 is provided with a connecting positioning arm 11, the front end of the crushing device body 12 is provided with a buffer pillow 13, the bottom of the crushing device body 12 is provided with a support frame 17, and the rear end of the support frame 17 is provided with a support frame 2 18.

[0030] In practical use, by placing the cell environment on the placement seat, the cells are positioned above the cell disruption device body 12, and then the cloud transmits a signal to the cell disruption device body 1, causing the lateral positioning end 15 to slide on the side of the adjustment track 14.

[0031] In use, the high-efficiency continuous cell disruption device of this invention first places the cell environment on the placement seat, so that the cells are placed above the main body 12 of the disruption device. Then, a signal is transmitted from the cloud to the main body 1 of the cell disruption device, so that the lateral positioning end 15 slides on the side of the adjustment track 14, and the cell disruption component 2 is moved to the cell placement seat position. After the anesthetized cells are disrupted, the cell disruption component 2 controls the telescopic cylinder 22, which drives the telescopic rod 21 to descend, so that its end disruption device 27 moves to the appropriate disruption position. The adjustment key block 26 slides down to disrupt the internal cells. The auxiliary disruption disc 24 stabilizes the telescopic rod 21 and prevents it from shaking during disruption, so that the whole device is very stable, reliable and flexible. The air pressure connection end 31 of the positioning component 3 connects the two ends of the regulator 2 37 and regulator 1 34. The difference in input air pressure at the two ends causes the adjustment slide rod 36 to slide inside the regulator, which drives the positioning block 2 35 and positioning block 1 33 to move laterally, and moves the positioning disc 32. This can prevent the device from being inconvenient to change and adjust after positioning is completed, and improve its practicality.

[0032] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely preferred examples and are not intended to limit the utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A high-efficiency continuous cell disruption device, comprising a cell disruption device body (1), characterized in that: A cell disruption assembly (2) is installed at the front end of the cell disruption device body (1). A telescopic cylinder (22) is fixedly installed on the side of the cell disruption assembly (2). A telescopic rod (21) is installed at the output end of the telescopic cylinder (22). A positioning plate (23) is installed on the front side of the telescopic rod (21). An auxiliary disruption disc (24) is installed on the end side of the telescopic rod (21). A disruption device (27) is fixedly installed below the end of the telescopic rod (21). A viewing glass plate (25) is opened on the side of the disruption device (27).

2. The high-efficiency continuous cell disruption device as described in claim 1, characterized in that: An adjustment key block (26) is installed on the side of the viewing glass plate (25), and a positioning component (3) is installed on the side of the cell disruption component (2).

3. The high-efficiency continuous cell disruption device as described in claim 2, characterized in that: The output end of the positioning component (3) is equipped with a pneumatic connection end (31), and a regulator two (37) is installed below the pneumatic connection end (31). The output end of the regulator two (37) is provided with an adjustment slide rod (36). The side of the adjustment slide rod (36) is fixedly connected to a positioning block two (35), and the side of the positioning block two (35) is fixedly installed with a moving disk (32).

4. The high-efficiency continuous cell disruption device as described in claim 3, characterized in that: A positioning block (33) is fixedly installed below the moving disk (32), an adjuster (34) is provided on the right side of the positioning block (33), and a crushing device body (12) is provided below the adjuster (34).

5. The high-efficiency continuous cell disruption device as described in claim 4, characterized in that: The side of the main body (12) of the crushing device is provided with an adjustment rail (14), and the side of the adjustment rail (14) is slidably connected with a transverse positioning end (15).

6. The high-efficiency continuous cell disruption device as described in claim 5, characterized in that: An adjustment plate (16) is installed on the side of the transverse positioning end (15), and a connecting positioning arm (11) is provided above the adjustment plate (16). A buffer pillow (13) is provided at the front end of the main body (12) of the crushing device.

7. The high-efficiency continuous cell disruption device as described in claim 6, characterized in that: A support frame (17) is installed below the main body (12) of the crushing device.

8. The high-efficiency continuous cell disruption device as described in claim 7, characterized in that: Support frame 2 (18) is provided at the rear end of support frame 1 (17).

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