A gel dialysis device

Abstract

The utility model discloses a kind of gel dialysis equipment, including injection water pipeline, compressed air pipeline, liquid preparation tank, elution tank and PLC control cabinet, the utility model is set up gravity sensor and pressure sensor on liquid preparation tank and elution tank, so that gravity sensor monitors the weight in liquid preparation tank and elution tank, pressure sensor monitors the pressure in liquid preparation tank and elution tank, and the data of monitoring is transmitted to PLC control cabinet in real time, PLC control cabinet controls the opening and closing of valve on each pipeline, to realize automatic control entire dialysis process, entire dialysis process operation is convenient, can liberate labor, reduce production cost, reduce pollution rate, improve dialysis efficiency.

Description

Technical Field

[0001] This utility model relates to the field of biomedical material manufacturing equipment, specifically to a gel dialysis device. Background Technology

[0002] In the process of preparing cross-linked polymer gels by cross-linking polymer compounds with chemical cross-linking agents, dialysis is often used to remove excess cross-linking agents. CN108395552B discloses a method for preparing monophase cross-linked sodium hyaluronate gel, specifically: sodium hyaluronate alkaline treatment - 1,4-butanediol diglycidyl ether (BDDE) cross-linking reaction - dialysis with dialysate - preliminary granulation - colloid mill granulation. CN115279330A discloses a cross-linked HA-collagen hydrogel as a dermal filler, which uses 1-ethyl-3-(N,N'-dimethylaminopropyl)carbodiimide (EDC) / N-hydroxysuccinimide (NHS) to prepare the cross-linked HA-collagen hydrogel, and removes EDC / NHS by dialysis. CN111068114B discloses a method for preparing a mannitol-containing injectable modified sodium hyaluronate gel. After obtaining a sodium hyaluronate cross-linked gel, the mannitol component is dissolved in a dialysis solution, and the mannitol is dialyzed into the gel and uniformly distributed inside through a special dialysis process to obtain a mannitol-containing injectable modified sodium hyaluronate gel.

[0003] Patent CN108395552B requires changing the dialysis fluid at intervals of 1 hour, 6 hours, and 16 hours, with 10L each time. Patent CN115279330A requires dialysis of the gel formulation with PBS dialysis fluid at 2℃ to 8℃ for approximately 70 hours, during which the PBS dialysis fluid is changed several times to remove EDC / NHS. Patent CN111068114B requires adding 5L of dialysis fluid ① to the cut gel and dialysis for 1.5 hours, then removing it and equilibrating it at 30℃ for 45 minutes, followed by adding another 5L of dialysis fluid ② for three dialysis cycles at 4 hours, 16 hours, and 2 hours, until the final weight of the gel is 800g, at which point dialysis is stopped. Therefore, current dialysis processes not only have long dialysis times and require frequent changes of dialysis fluid, but also have inconsistent intervals between changes and require control of the dialysis fluid temperature. However, in the current technology, there is no automated gel dialysis equipment. Each dialysis session requires manual preparation of the dialysis solution and manual monitoring of the time, as well as manual replacement of the dialysis solution on time. This greatly consumes the operator's time, increases the difficulty of operation, and poses a possibility of manual contamination of the gel, which is very unfavorable for industrial dialysis. Summary of the Invention

[0004] The purpose of this invention is to overcome the shortcomings of the prior art and provide a gel dialysis device to solve the problem of high labor costs and unfavorable conditions for industrial dialysis caused by the lack of automated gel dialysis equipment in the existing dialysis process.

[0005] To achieve the above objectives, this utility model provides a gel dialysis device, which includes a water-for-injection pipeline 1, a compressed air pipeline 2, a solution preparation tank 3, an elution tank 4, and a PLC control cabinet 5.

[0006] The water-for-injection pipeline 1 and the compressed air pipeline 2 are respectively connected to the mixing tank 3 and the elution tank 4, and are used to inject water for injection or compressed air into the mixing tank 3 and the elution tank 4.

[0007] The mixing tank 3 is used to prepare dialysis solution. The mixing tank 3 is equipped with a feed port 31 and a dialysis solution delivery pipe 6 and a first sewage discharge pipe 7 connected to the elution tank 4.

[0008] The elution tank 4 is used for dialysis gel. The elution tank 4 is equipped with a second drain pipe 8. The elution tank 4 is equipped with a dialysate circulation device 9 and / or an air distributor 10. The dialysate circulation device 9 and the air distributor 10 are used to make the dialysate in the elution tank 4 flow.

[0009] The liquid preparation tank 3 and the elution tank 4 are each equipped with a gravity sensor 32 and a pressure sensor 33. Valves are installed on the above-mentioned pipelines. The gravity sensor 32, the pressure sensor 33, and each valve are electrically connected to the PLC control cabinet 5.

[0010] Furthermore, the water for injection pipeline 1 is connected to the solution preparation tank 3 and the elution tank 4 via the first water for injection pipeline 11 and the second water for injection pipeline 12, respectively, and the compressed air pipeline 2 is connected to the solution preparation tank 3 and the elution tank 4 via the first compressed air pipeline 21 and the second compressed air pipeline 22, respectively.

[0011] Furthermore, the first water for injection pipeline 11 and the second water for injection pipeline 12 are respectively provided with a first cleaning pipeline 13 and a second cleaning pipeline 14. The outlets of the first cleaning pipeline 13 and the second cleaning pipeline 14 are each provided with a spray ball 15 for cleaning the solution tank 3 and the elution tank 4. The first cleaning pipeline 13 is provided with a valve E105, and the second cleaning pipeline 14 is provided with a valve F106. The valves E105 and F106 are electrically connected to the PLC control cabinet 5.

[0012] Furthermore, the liquid preparation tank 3 is equipped with a stirrer 34, which is electrically connected to the PLC control cabinet 5.

[0013] Furthermore, both the first sewage pipe 7 and the second sewage pipe 8 are equipped with conductivity sensors 71, and the conductivity sensors 71 are electrically connected to the PLC control cabinet 5.

[0014] Furthermore, the first compressed air pipeline 21 and the second compressed air pipeline 22 are respectively provided with a first pressure relief pipeline 23 and a second pressure relief pipeline 24. The first pressure relief pipeline 23 is provided with a valve J110, and the second pressure relief pipeline 24 is provided with a valve K111. The valves J110 and K111 are electrically connected to the PLC control cabinet 5.

[0015] Furthermore, it also includes a heating and cooling integrated unit 36, which is used to control the temperature of the liquid preparation tank 3 and the elution tank 4. Both the liquid preparation tank 3 and the elution tank 4 are equipped with temperature sensors 35. The heating and cooling integrated unit 36 ​​and the temperature sensors 35 are electrically connected to the PLC control cabinet 5.

[0016] Furthermore, it also includes an ultrasonic generator 37 and an ultrasonic transducer 38. The ultrasonic generator 37 is electrically connected to the ultrasonic transducer 38 and the PLC control cabinet 5, and provides electrical power to the ultrasonic transducer 38. The ultrasonic transducer 38 is connected to the elution tank 4 and is used to radiate ultrasonic waves to the elution tank 4.

[0017] Furthermore, the air distributor 10 is connected to the compressed air pipeline 2 via valve L112, and valve L112 is electrically connected to the PLC control cabinet 5.

[0018] Furthermore, the dialysate circulation device 9 includes a first liquid guide pipe 91 connected to the upper end of the elution tank 4 and a second liquid guide pipe 92 connected to the lower end of the elution tank 4, as well as a peristaltic pump 93 connecting the first liquid guide pipe 91 and the second liquid guide pipe 92. The peristaltic pump 93 is electrically connected to the PLC control cabinet 5.

[0019] Compared with the prior art, the present invention has the following beneficial technical effects:

[0020] This invention installs gravity and pressure sensors on the mixing tank and elution tank. The gravity sensors monitor the weight inside the mixing tank and elution tank, while the pressure sensors monitor the pressure inside. The monitored data is transmitted to the PLC control cabinet in real time. The PLC control cabinet controls the opening and closing of valves on various pipelines, thereby achieving automatic control of the entire dialysis process. The entire dialysis process is easy to operate, which can free up labor, reduce production costs, reduce contamination rates, and improve dialysis efficiency. Attached Figure Description

[0021] To more clearly illustrate the embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings in the following description are merely exemplary, and those skilled in the art can derive other embodiments based on the provided drawings without creative effort.

[0022] The structures, proportions, sizes, etc. illustrated in this specification are only for the purpose of assisting those skilled in the art in understanding and reading the content disclosed herein, and are not intended to limit the implementation conditions of this utility model. Therefore, they have no substantial technical significance. Any modifications to the structure, changes in the proportional relationships, or adjustments to the size, without affecting the effects and purposes that this utility model can produce, should still fall within the scope of the technical content disclosed in this utility model.

[0023] Figure 1 This is a structural schematic diagram of Example 1;

[0024] Figure 2 This is a structural schematic diagram of Example 2;

[0025] Figure 3 This is a schematic diagram of the structure of Example 3;

[0026] Figure 4 This is a structural schematic diagram of Example 4.

[0027] Figure 5 This is a structural schematic diagram of Example 5.

[0028] In the diagram: 1. Water for injection pipeline; 2. Compressed air pipeline; 3. Mixing tank; 4. Eluent tank; 5. PLC control cabinet; 11. First water for injection pipeline; 12. Second water for injection pipeline; 13. First cleaning pipeline; 14. Second cleaning pipeline; 15. Spray ball; 21. First compressed air pipeline; 22. Second compressed air pipeline; 23. First pressure relief pipeline; 24. Second pressure relief pipeline; 31. Feed port; 32. Gravity sensor; 33. Pressure sensor; 34. Stirrer; 35. Temperature sensor; 36. Integrated heating and cooling unit; 37. Ultrasonic generator. 38. Ultrasonic transducer; 41. Dialysis stand; 6. Dialysis fluid pipeline; 7. First drain pipeline; 71. Conductivity sensor; 8. Second drain pipeline; 9. Dialysis fluid circulation device; 91. Fluid guide tube one; 92. Fluid guide tube two; 93. Peristaltic pump; 10. Air distributor; 101. Valve A; 102. Valve B; 103. Valve C; 104. Valve D; 105. Valve E; 106. Valve F; 107. Valve G; 108. Valve H; 109. Valve I; 110. Valve J; 111. Valve K; 112. Valve L. Detailed Implementation

[0029] The following specific embodiments illustrate the implementation of this utility model. Those skilled in the art can easily understand other advantages and effects of this utility model from the content disclosed in this specification. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of this utility model.

[0030] To make the objectives and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and embodiments.

[0031] Example 1

[0032] like Figure 1 As shown, this utility model provides a gel dialysis device, including a water-for-injection pipeline 1, a compressed air pipeline 2, a solution preparation tank 3, an elution tank 4, and a PLC control cabinet 5; the water-for-injection pipeline 1 and the compressed air pipeline 2 are respectively connected to the solution preparation tank 3 and the elution tank 4, and are used to inject water for injection or compressed air into the solution preparation tank 3 and the elution tank 4.

[0033] The mixing tank 3 is used to prepare dialysis solution. The mixing tank 3 is equipped with a feed port 31 and a dialysis solution delivery pipe 6 and a first sewage discharge pipe 7 connected to the elution tank 4.

[0034] The elution tank 4 is used for dialysis gel. The elution tank 4 is equipped with a second drain pipe 8 and an air distributor 10, which is used to make the dialysis fluid in the elution tank 4 flow.

[0035] The liquid preparation tank 3 and the elution tank 4 are each equipped with a gravity sensor 32 and a pressure sensor 33. Valves are installed on the above-mentioned pipelines. The gravity sensor 32, the pressure sensor 33, and each valve are electrically connected to the PLC control cabinet 5.

[0036] This invention uses gravity sensors and pressure sensors installed on the mixing tank and elution tank. The gravity sensors monitor the weight inside the mixing tank and elution tank, and the pressure sensors monitor the pressure inside the mixing tank and elution tank. The monitored data is transmitted to the PLC control cabinet in real time, and the PLC control cabinet controls the opening and closing of valves on each pipeline, thereby realizing automatic control of the entire dialysis process.

[0037] Example 2

[0038] like Figure 2As shown, the water for injection pipeline 1 is connected to the solution preparation tank 3 and the elution tank 4 via the first water for injection pipeline 11 and the second water for injection pipeline 12, respectively. The compressed air pipeline 2 is connected to the solution preparation tank 3 and the elution tank 4 via the first compressed air pipeline 21 and the second compressed air pipeline 22, respectively.

[0039] The feed port 31 is located at the top of the preparation tank 3 to facilitate the addition of solid materials during the preparation of dialysis solution. For example, when preparing PBS dialysis solution, solid materials such as Na2HPO4, KH2PO4, NaCl, and KCl need to be added. The bottom of the preparation tank 3 is conical, and the dialysis solution pipe 6 and the first drain pipe 7 are connected to the bottom of the preparation tank 3 to facilitate the discharge of dialysis solution or waste liquid.

[0040] The solution preparation tank 3 is equipped with a solution preparation tank cover on top for sealing the solution preparation tank 3. The elution tank 4 is equipped with an elution tank cover on top for sealing the elution tank 4.

[0041] The elution vessel 4 is equipped with a dialysis rack 41. The dialysis rack 41 can be used to suspend or place the gel to be dialyzed, wherein the gel to be dialyzed needs to be wrapped in a dialysis membrane bag before being suspended or placed on the dialysis rack 41.

[0042] The second drain pipe 8 is connected to the bottom of the washing tank 4. The washing tank 4 is equipped with an air distributor 10, which is used to introduce compressed air into the washing tank 4.

[0043] The first water for injection pipeline 11 is equipped with valve A101, the second water for injection pipeline 12 is equipped with valve B102, the first compressed air pipeline 21 is equipped with valve C103, the second compressed air pipeline 22 is equipped with valve D104, the dialysate pipeline 6 is equipped with valve G107, the first sewage pipeline 7 is equipped with valve H108, and the second sewage pipeline 8 is equipped with valve I109. The PLC control cabinet 5 includes a PLC programmable logic controller, a human-machine interface, and electrical control components, and is electrically connected to each valve.

[0044] Valves A101, B102, G107, H108, and I109 are pneumatic diaphragm valves, and valves C103 and D104 are pneumatic ball valves.

[0045] The volume of the liquid preparation tank 3 is set according to actual production needs, and can be 100L. The volume of the elution tank 4 is set according to actual production needs, and can be 50L.

[0046] The first water for injection pipeline 11 and the second water for injection pipeline 12 are respectively provided with a first cleaning pipeline 13 and a second cleaning pipeline 14. The outlets of the first cleaning pipeline 13 and the second cleaning pipeline 14 are each provided with a spray ball 15 for cleaning the solution tank 3 and the elution tank 4. The first cleaning pipeline 13 is provided with a valve E105 and the second cleaning pipeline 14 is provided with a valve F106. The valves E105 and F106 are electrically connected to the PLC control cabinet 5.

[0047] The liquid preparation tank 3 is equipped with a stirrer 34, which is electrically connected to the PLC control cabinet 5. Figure 2 The stirrer 34 shown is a magnetic stirrer. Of course, an electric stirrer with a stirring paddle can also be set as needed. There is no limitation on the model of the stirrer, as long as it meets the requirement of stirring and dissolving materials in the preparation of dialysis solution.

[0048] The first sewage pipe 7 and the second sewage pipe 8 are both equipped with conductivity sensors 71, and the conductivity sensors 71 are electrically connected to the PLC control cabinet 5.

[0049] The first compressed air pipeline 21 and the second compressed air pipeline 22 are respectively provided with a first pressure relief pipeline 23 and a second pressure relief pipeline 24. The first pressure relief pipeline 23 is provided with a valve J110 and the second pressure relief pipeline 24 is provided with a valve K111. The valves J110 and K111 are electrically connected to the PLC control cabinet 5.

[0050] The air distributor 10 is connected to the compressed air pipeline 2 via valve L112, and valve L112 is electrically connected to the PLC control cabinet 5.

[0051] During runtime, the steps are as follows:

[0052] (1) Preparation of dialysis solution: Start the solution preparation program, open valve A101, and inject water for injection into the solution preparation tank 3. Gravity sensor 32 monitors the weight of water for injection in real time. After the water injection is completed, manually add the material through the feeding port 31 according to the formula. After adding the material, start stirring (the stirring speed and time of the stirrer 34 are set through the PLC control cabinet 5). After the material is completely dissolved, automatically open valve C103 on the first compressed air pipeline 21, valve G107 on the dialysis solution pipeline 6, and valve K111 on the second pressure relief pipeline 24. Compressed air enters the solution preparation tank 3 through the first compressed air pipeline 21, and pressurizes the prepared dialysis solution into the elution tank 4 through the dialysis solution delivery pipeline 6. Pressure sensor 33 monitors the pressure inside the tank in real time to ensure that the solution preparation tank 3 is safe and effective.

[0053] (2) Dialysis: Open the eluent tank lid of the eluent tank 4, put in the gel to be dialyzed, and close the eluent tank lid. The eluent tank 4 is also equipped with a gravity sensor 32. After the dialysate in the eluent tank 4 reaches the set weight, valves C103 and G107 will be automatically closed. At this time, the equipment will automatically open valve L112 on the air distributor 10 to blow air into the eluent tank 4 and start dialysis. Blowing in air can promote the flow of dialysate, thereby accelerating the dialysis efficiency.

[0054] The type of air distributor 10 can be selected as needed, and the pressure of compressed air can be adjusted (by setting a pressure regulating valve at the inlet end of the air distributor 10 to adjust the pressure) to control the airflow speed, etc.

[0055] (3) After the first dialysis session has ended, valve L112 on the air distributor 10 will automatically close, and valve I109 on the second drain pipe 8 will open to drain the dialysate. If the dialysate cannot be drained automatically, valve K111 on the second pressure relief pipe 24 will automatically close, and valve D104 on the second compressed air pipe 22 will open to blow in compressed air, thereby draining the dialysate. The first dialysis session ends, and the second dialysis session begins.

[0056] (4) Automatically open valve C103 on the first compressed air pipeline 21, valve G107 on the dialysate pipeline 6, and valve K111 on the second pressure relief pipeline 24, and close valve D104 on the second compressed air pipeline 22. The compressed air will pressurize the prepared dialysate into the washing tank 4.

[0057] The weight of the dialysate in the preparation tank 3 can be 3 to 5 times the weight of the dialysate required for each dialysis session. This eliminates the need for frequent preparation of dialysate. Moreover, even if the dialysate needs to be changed at night, the equipment can automatically complete the dialysis as long as there is sufficient dialysate in the preparation tank 3, eliminating the need for personnel to work night shifts and facilitating industrialized dialysis production. When the dialysate in the preparation tank 3 is insufficient, the dialysate preparation operation in step (1) is repeated.

[0058] (5) Once the dialysate in the elution tank 4 reaches the set weight, valves C103 and G107 are automatically closed. At this time, the equipment automatically opens valve L112 on the air distributor 10 to blow air into the elution tank 4, initiating dialysis. After several dialysis cycles, the dialysate is discharged. The gel in the elution tank 4 is removed, and the automatic cleaning program is started. Valve E105 on the first cleaning pipe 13 and valve F106 on the second cleaning pipe 14 are opened to clean the solution tank 3 and the elution tank 4 through the spray ball 15. Simultaneously, valve H108 on the first drain pipe 7 and valve I109 on the second drain pipe 8 are opened to discharge the cleaned liquid. In addition, the conductivity sensor 71 on the first drain pipe 7 and the second drain pipe 8 detects that the discharged liquid has reached the set conductivity and stops the cleaning program. When the PLC completes the set operation, it enters standby mode, and the next gel sample can be dialyzed.

[0059] The spray ball 15 can make cleaning more thorough.

[0060] Example 3

[0061] like Figure 3 As shown, compared to Example 1, the difference is that the air distributor 10 is replaced with a dialysate circulation device 9. The dialysate circulation device 9 includes a first guide pipe 91 connected to the upper end of the eluent tank 4 and a second guide pipe 92 connected to the lower end of the eluent tank 4, as well as a peristaltic pump 93 connecting the first guide pipe 91 and the second guide pipe 92. The peristaltic pump 93 is electrically connected to the PLC control cabinet 5. The dialysate circulation device 9 is used to circulate the dialysate within the eluent tank 4, thereby accelerating dialysis efficiency.

[0062] The air distributor 10 and the dialysate circulation device 9 can be used simultaneously as needed for dialysis, thereby increasing dialysis efficiency.

[0063] Example 4

[0064] like Figure 4 As shown, compared with Embodiment 1, a cooling and heating integrated unit 36 ​​and a temperature sensor 35 are added. The cooling and heating integrated unit 36 ​​is used to control the temperature of the solution preparation tank 3 and the elution tank 4. The solution preparation tank 3 and the elution tank 4 are both equipped with temperature sensors 35. The cooling and heating integrated unit 36 ​​and the temperature sensor 35 are electrically connected to the PLC control cabinet 5, thereby meeting the temperature control requirements in the dialysis process.

[0065] Example 5

[0066] like Figure 5As shown, compared with Embodiment 1, an ultrasonic generator 37 and an ultrasonic transducer 38 are added. The ultrasonic generator 37 is electrically connected to the ultrasonic transducer 38 and the PLC control cabinet 5, and provides electrical power to the ultrasonic transducer 38. The ultrasonic transducer 38 is connected to the elution tank 4 and is used to radiate ultrasonic waves to the elution tank 4, so as to accelerate the flow of the dialysate in the elution tank 4 and increase the dialysis efficiency.

[0067] The ultrasonic generator 37 can provide different electrical power to the ultrasonic transducer 38 according to different instructions from the PLC controller 5. The ultrasonic transducer 38 can convert the different input electrical power into ultrasonic waves of corresponding frequencies. Specifically, the greater the input electrical power, the higher the frequency of the ultrasonic waves generated by the ultrasonic transducer 38. The higher the frequency of the ultrasonic waves, the faster the dialysate flows, which accelerates the ion exchange between the dialysate and the gel and improves the dialysis efficiency.

[0068] Example 6

[0069] Compared with Example 1, filters can be installed on the compressed air pipeline 2 or the dialysis fluid pipeline 6 according to actual industrial needs, and sight glasses with lights and anti-arch rupture discs can be installed on the liquid preparation tank 3 and the elution tank 4 to meet the needs of industrial production.

Claims

1. A gel dialysis device, characterized in that, It includes a water for injection pipeline (1), a compressed air pipeline (2), a solution preparation tank (3), an elution tank (4), and a PLC control cabinet (5); The water for injection pipeline (1) and the compressed air pipeline (2) are respectively connected to the mixing tank (3) and the elution tank (4) for injecting water for injection or compressed air into the mixing tank (3) and the elution tank (4); The solution preparation tank (3) is used to prepare dialysis solution. The solution preparation tank (3) is provided with a feed port (31) and a dialysis solution delivery pipe (6) and a first sewage discharge pipe (7) connected to the elution tank (4). The elution tank (4) is used for dialysis gel. The elution tank (4) is provided with a second drain pipe (8). The elution tank (4) is provided with a dialysate circulation device (9) and / or an air distributor (10). The dialysate circulation device (9) and the air distributor (10) are used to make the dialysate in the elution tank (4) flow. The liquid preparation tank (3) and the elution tank (4) are each equipped with a gravity sensor (32) and a pressure sensor (33), and the above-mentioned pipelines are each equipped with a valve. The gravity sensor (32), the pressure sensor (33), and each valve are electrically connected to the PLC control cabinet (5).

2. The gel dialysis device of claim 1, wherein, The water for injection pipeline (1) is connected to the mixing tank (3) and the elution tank (4) through the first water for injection pipeline (11) and the second water for injection pipeline (12), respectively. The compressed air pipeline (2) is connected to the mixing tank (3) and the elution tank (4) through the first compressed air pipeline (21) and the second compressed air pipeline (22), respectively.

3. The gel dialysis device according to claim 2, characterized in that, The first water for injection pipeline (11) and the second water for injection pipeline (12) are respectively provided with a first cleaning pipeline (13) and a second cleaning pipeline (14). The outlets of the first cleaning pipeline (13) and the second cleaning pipeline (14) are each provided with a spray ball (15) for cleaning the liquid preparation tank (3) and the elution tank (4).

4. The gel dialysis device according to claim 1, characterized in that, The liquid preparation tank (3) is equipped with a stirrer (34), which is electrically connected to the PLC control cabinet (5).

5. The gel dialysis apparatus according to claim 1, characterized in that, The first sewage pipe (7) and the second sewage pipe (8) are each equipped with a conductivity sensor (71), and the conductivity sensor (71) is electrically connected to the PLC control cabinet (5).

6. The gel dialysis apparatus according to claim 2, characterized in that, The first compressed air pipe (21) and the second compressed air pipe (22) are respectively provided with a first pressure relief pipe (23) and a second pressure relief pipe (24).

7. The gel dialysis apparatus according to claim 1, characterized in that, It also includes a heating and cooling unit (36), which is used to control the temperature of the liquid preparation tank (3) and the elution tank (4). The liquid preparation tank (3) and the elution tank (4) are equipped with temperature sensors (35). The heating and cooling unit (36) and the temperature sensors (35) are electrically connected to the PLC control cabinet (5).

8. The gel dialysis apparatus according to claim 1, characterized in that, It also includes an ultrasonic generator (37) and an ultrasonic transducer (38), wherein the ultrasonic generator (37) is electrically connected to the ultrasonic transducer (38) and the PLC control cabinet (5) and provides electrical power to the ultrasonic transducer (38), and the ultrasonic transducer (38) is connected to the elution tank (4) and is used to radiate ultrasonic waves to the elution tank (4).

9. The gel dialysis apparatus according to claim 1, characterized in that, The air distributor (10) is connected to the compressed air pipeline (2) via valve L (112), and valve L (112) is electrically connected to the PLC control cabinet (5).

10. The gel dialysis apparatus according to claim 1, characterized in that, The dialysate circulation device (9) includes a first liquid guide pipe (91) connected to the upper end of the elution tank (4) and a second liquid guide pipe (92) connected to the lower end of the elution tank (4), as well as a peristaltic pump (93) connecting the first liquid guide pipe (91) and the second liquid guide pipe (92). The peristaltic pump (93) is electrically connected to the PLC control cabinet (5).

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