A concentrated dispensing device for small-volume injection production
By using a concentration device with stirring and linkage components in the production of small-volume injections, the problem of drug residue sticking to the wall was solved, the mixing efficiency and uniformity were improved, and the quality and stability of the injections were guaranteed.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- JIANGSU LIANHUAN PHARMA
- Filing Date
- 2025-07-25
- Publication Date
- 2026-06-26
AI Technical Summary
Traditional stirring methods can easily lead to drug residue sticking to the walls in the production of small-volume injections, reducing mixing efficiency and uniformity, and affecting product quality and stability.
A concentration device including a stirring component and a linkage component is adopted. The movement of the baffle plate is driven by the meshing of gears and racks, which reduces the phenomenon of drug liquid sticking to the wall and improves the mixing uniformity.
It improves mixing efficiency, ensures the quality and stability of the injection, and avoids uneven mixing.
Smart Images
Figure CN224404979U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of injectable drug production, and in particular to a concentration preparation device for the production of small-volume injectable drugs. Background Technology
[0002] In the pharmaceutical manufacturing field, injectable drugs, as an important dosage form, are widely used in clinical treatment due to their rapid action, high reliability, and insensitivity to physiological environmental factors such as pH, enzymatic activity, and food. They are especially indispensable for patients who cannot take oral medications or whose specific conditions require them. In the production of small-volume injectable drugs, ensuring the uniform mixing of the drug components with the solvent (usually water) is a crucial step in guaranteeing drug quality and efficacy.
[0003] Currently, the production of small-volume injections generally employs concentration equipment to mix drugs with water. In this process, stirring is the primary means of achieving uniform mixing.
[0004] Traditional mixing methods typically rely on the rotation of a stirring paddle within a mixing tank to propel fluid movement and achieve mixing. However, this method has a significant drawback: during mixing, the centrifugal force generated by the rotating paddle causes some of the injectable drug solution to be thrown against the inner wall of the mixing tank, creating a phenomenon known as "wall adhesion." This not only reduces the effective mixing material within the mixing area, lowers mixing efficiency, and increases the time required to achieve uniform mixing, but may also lead to uneven mixing, affecting the quality and stability of the final product. Utility Model Content
[0005] This invention aims to at least partially solve one of the technical problems in related technologies. To this end, this invention proposes a concentration preparation device for the production of small-volume injections.
[0006] The technical solution adopted by this utility model to solve its technical problem is: a concentrated preparation device for the production of small-volume injections, including a stirring tank, the top of which is provided with a feed inlet and the bottom of which is provided with a discharge outlet; the surface and interior of the stirring tank are provided with a stirring component for stirring the injection solution and a linkage component for improving the uniformity of stirring.
[0007] The linkage component includes:
[0008] A fixing frame is fixed to the top of the mixing tank, and a sliding rod is slidably connected to the bottom of the fixing frame;
[0009] A protrusion is disposed inside the slide bar, and the bottom of the protrusion is fixed to the top of the gear two; the gear two is driven by the stirring assembly.
[0010] A slide bar, on the surface of which is fixed a rack, the slide bar being used to drive the rack to move synchronously;
[0011] Rack 1, used to drive the movement of the moving parts installed inside the mixing tank;
[0012] The movable part is used to draw the injectable drug solution inward.
[0013] In a preferred embodiment of this utility model, the movable component includes a fixed rod that penetrates the mixing tank and is rotatably connected to the mixing tank. A gear three is fixed to the top of the fixed rod, and the gear three meshes with a rack one. A gear four is fixed to the bottom of the fixed rod and is rotatably connected to the top of the inner wall of the mixing tank. A gear ring is rotatably connected to the top of the inner wall of the mixing tank, and the gear ring meshes with the gear three. A baffle is slidably connected to the top of the inner wall of the mixing tank, and a rack two is fixed to the surface of the baffle. A gear five is rotatably connected to the top of the inner wall of the mixing tank, and the gear five meshes with the gear ring. The rack two meshes with the gear five.
[0014] In a preferred embodiment of the present invention, the baffle is an arc-shaped plate that protrudes from the center of the mixing tank toward the inner wall of the mixing tank.
[0015] In a preferred embodiment of this utility model, the surface of the spoiler is provided with perforations.
[0016] In a preferred embodiment of the present invention, the stirring assembly includes a motor, which is fixed to the top of the stirring tank. A gear one is fixed to the top of the output shaft of the motor. A rotating rod is provided on the surface of the stirring tank, which passes through the stirring tank and is rotatably connected to the stirring tank. A gear two is fixed to the top of the rotating rod, and the gear one meshes with the gear two. A stirring rod is fixed to the surface of the rotating rod.
[0017] In a preferred embodiment of the present invention, a solenoid valve is fixed at the bottom of the mixing tank, the discharge port is connected to the mixing tank through the solenoid valve, and a heating plate is installed on the outer surface of the mixing tank.
[0018] The beneficial effects of this utility model are as follows: the stirring assembly is used to stir and mix the raw materials. At the same time, the stirring assembly drives the linkage assembly. When the motor starts, gear one drives gear two to rotate, the convex block rotates synchronously, the surface of the convex block abuts against the slide rod, and the slide rod moves back and forth inside the fixed frame. Rack one drives gear three, the fixed rod, and gear four to move back and forth synchronously. At this time, gear five drives rack two and the baffle to move back and forth, which can make the injection liquid affected by centrifugal force gather inward, improve the stirring efficiency, avoid uneven stirring, and thus ensure the product quality and stability of the injection. Attached Figure Description
[0019] Figure 1 This is a front view structural diagram of the present invention;
[0020] Figure 2 This is a bottom-view schematic diagram of the internal structure of this utility model;
[0021] Figure 3 This is a front view structural diagram of the stirring assembly and linkage assembly of this utility model;
[0022] Figure 4 This utility model Figure 3 A schematic diagram of the enlarged structure of A in the middle;
[0023] Figure 5 This is a top view of the movable part of this utility model.
[0024] In the diagram: 1. Mixing tank; 2. Heating plate; 3. Feed inlet; 4. Discharge outlet; 5. Solenoid valve; 6. Mixing assembly; 60. Motor; 61. Gear 1; 62. Gear 2; 63. Rotating rod; 64. Mixing rod; 7. Linkage assembly; 70. Fixing frame; 71. Protrusion; 72. Slide rod; 73. Rack 1; 74. Moving part; 740. Gear 3; 741. Fixing rod; 742. Gear 4; 743. Gear ring; 744. Rack 2; 745. Gear 5; 746. Baffle. Detailed Implementation
[0025] The embodiments of this utility model are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this utility model, and should not be construed as limiting this utility model.
[0026] In the description of this utility model, it should be understood that the terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," and "counterclockwise," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description. They do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, features defined with "first" and "second" may explicitly or implicitly include one or more of the stated features. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly specified.
[0027] like Figures 1 to 5 The present invention discloses a concentrated preparation device for the production of small-volume injections, including a stirring tank 1, wherein the top of the stirring tank 1 is provided with a feed inlet 3 and the bottom of the stirring tank 1 is provided with a discharge outlet 4; the surface and interior of the stirring tank 1 are provided with a stirring component 6 for stirring the injection solution and a linkage component 7 for improving the stirring uniformity.
[0028] The linkage component 7 includes:
[0029] A fixing frame 70 is fixed to the top of the mixing tank 1, and a sliding rod 72 is slidably connected to the bottom of the fixing frame 70;
[0030] A protrusion 71 is disposed inside the slide bar 72, and the bottom of the protrusion 71 is fixed to the top of the gear 62; the gear 62 is driven by the stirring assembly 6.
[0031] A slide rod 72, on the surface of which a rack 73 is fixed, the slide rod 72 is used to drive the rack 73 to move synchronously;
[0032] Rack 73 is used to drive the movable part 74 installed in the mixing tank 1.
[0033] Movable part 74 is used to draw the injectable drug solution inward.
[0034] In a preferred embodiment, the movable component 74 in this application includes a fixed rod 741 that passes through the mixing tank 1 and is rotatably connected to the mixing tank 1. A gear 3 740 is fixed to the top of the fixed rod 741 and meshes with a rack 1 73. A gear 4 742 is fixed to the bottom of the fixed rod 741 and is rotatably connected to the top of the inner wall of the mixing tank 1. A gear ring 743 is rotatably connected to the top of the inner wall of the mixing tank 1 and meshes with the gear 3 740. A baffle 746 is slidably connected to the top of the inner wall of the mixing tank 1. A rack 2 744 is fixed to the surface of the baffle 746. A gear 5 745 is rotatably connected to the top of the inner wall of the mixing tank 1 and meshes with the gear ring 743. The rack 2 744 meshes with the gear 5 745.
[0035] In this application, a fixing bracket 70 is fixed to the top of the mixing tank 1. A sliding rod 72 is slidably connected to the bottom of the fixing bracket 70. A protrusion 71 abuts against the inner side of the sliding rod 72. The bottom of the protrusion 71 is fixed to the top of the gear 62. A rack 73 is fixed to the surface of the sliding rod 72. A movable part 74 is provided on the surface and inside of the mixing tank 1. The movable part 74 includes a fixing rod 741, which passes through the mixing tank 1 and is rotatably connected to the mixing tank 1. A gear 740 is fixed to the top of the fixing rod 741 and meshes with the rack 73. A gear 742 is fixed to the bottom of the fixing rod 741 and is rotatably connected to the top of the inner wall of the mixing tank 1. A gear ring 743 is rotatably connected to the top of the inner wall of the mixing tank 1 and meshes with the gear 740. The top of the inner wall of the mixing tank 1 is slidably connected to the gear ring 742. A baffle plate 746 is attached, and a rack 744 is fixed to the surface of the baffle plate 746. A gear 745 is rotatably connected to the top of the inner wall of the mixing tank 1. The gear 745 meshes with the gear ring 743, and the rack 744 meshes with the gear 745. When the gear 742 rotates, the protrusion 71 rotates synchronously, and the surface of the protrusion 71 abuts against the slide rod 72. The slide rod 72 moves back and forth inside the fixed frame 70. At this time, the rack 73 moves back and forth synchronously, which makes the gear 740 rotate back and forth. At this time, the fixed rod 741 and the gear 742 move synchronously, which makes the gear ring 743 rotate back and forth synchronously. At this time, the gear 745 drives the rack 744 and the baffle plate 746 to move back and forth, which allows the injection liquid affected by centrifugal force to be gathered inward, improving the stirring efficiency and the uniformity of mixing, and ensuring the quality and stability of the injection product.
[0036] The baffle 746 described in this application is an arc-shaped plate protruding from the center of the mixing tank 1 toward the inner wall of the mixing tank 1, which facilitates the inward gathering of the injection liquid affected by centrifugal force, improves the mixing efficiency, and avoids uneven mixing.
[0037] The baffle 746 described in this application has a perforation on its surface, which will not affect the flow of the injectable drug solution.
[0038] In a preferred embodiment, the stirring assembly 6 of this application includes a motor 60, which is fixed to the top of the stirring tank 1. A gear 61 is fixed to the top of the output shaft of the motor 60. A rotating rod 63 is provided on the surface of the stirring tank 1, passing through the stirring tank 1 and rotatably connected to it. A gear 62 is fixed to the top of the rotating rod 63, and gears 61 and 62 mesh. A stirring rod 64 is fixed to the surface of the rotating rod 63. When the motor 60 is turned on, gear 61 drives gear 62 to rotate synchronously. At this time, the rotating rod 63 and the stirring rod 64 rotate, thus stirring and mixing the raw materials. A speed control switch is provided on the motor 60, and the speed of the motor 60 can be adjusted by rotating the control button of the speed control switch to regulate the stirring rate.
[0039] A solenoid valve 5 is fixed at the bottom of the mixing tank 1, and the discharge port 4 is connected to the mixing tank 1 through the solenoid valve 5. A heating plate 2 is installed on the outer surface of the mixing tank 1. By controlling the solenoid valve 5 to open, the raw material can be discharged through the discharge port 4.
[0040] When it is necessary to mix the injectable drug solution, the raw material is fed into the feed port 3. At this time, the heating plate 2 and the motor 60 are turned on. Gear 1 61 drives gear 2 62 to rotate synchronously. At the same time, the rotating rod 63 and the stirring rod 64 rotate to mix the raw material. Simultaneously, when gear 2 62 rotates, the protrusion 71 rotates synchronously. The surface of the protrusion 71 abuts against the sliding rod 72, which causes the sliding rod 72 to move back and forth inside the fixed frame 70. At the same time, rack 1 73 moves back and forth synchronously, which causes gear 3 740 to rotate back and forth. At the same time, the fixed rod 741 and gear 4 742 move synchronously, which causes the gear ring 743 to rotate back and forth synchronously. At the same time, gear 5 745 drives rack 2 744 and the baffle 746 to move back and forth, which allows the injectable drug solution affected by centrifugal force to be gathered inward, improving the mixing efficiency and avoiding uneven mixing. After mixing is completed, the solenoid valve 5 can be opened to allow the raw material to be discharged through the discharge port 4.
[0041] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "illustrative embodiment," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of this utility model. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.
[0042] In summary, although the present invention has been disclosed above with reference to preferred embodiments, the above preferred embodiments are not intended to limit the present invention. Those skilled in the art can make various modifications and refinements without departing from the spirit and scope of the present invention. Therefore, the scope of protection of the present invention shall be determined by the scope defined in the claims.
Claims
1. A concentration device for small volume injection production, characterized by, The mixture includes a mixing tank (1), which has a feed inlet (3) at the top and a discharge outlet (4) at the bottom; the surface and interior of the mixing tank (1) are provided with a stirring component (6) for stirring the injection solution and a linkage component (7) for improving the uniformity of stirring. The linkage component (7) includes: A fixing frame (70) is fixed to the top of the mixing tank (1), and a sliding rod (72) is slidably connected to the bottom of the fixing frame (70). A protrusion (71) is disposed inside a slide bar (72), and the bottom of the protrusion (71) is fixed to the top of a gear two (62); the gear two (62) is driven by a stirring assembly (6); A slide bar (72) has a rack (73) fixed on its surface. The slide bar (72) is used to drive the rack (73) to move synchronously. Rack 1 (73) is used to drive the moving part (74) installed in the mixing tank (1); Movable part (74) is used to draw the injectable drug solution inward.
2. The concentration device for small volume injection production according to claim 1, wherein The movable component (74) includes a fixed rod (741) that penetrates the mixing tank (1) and is rotatably connected to the mixing tank (1). A gear three (740) is fixed to the top of the fixed rod (741), meshing with a rack one (73). A gear four (742) is fixed to the bottom of the fixed rod (741), rotatably connected to the top of the inner wall of the mixing tank (1). (1) The top of the inner wall is rotatably connected to a gear ring (743), which meshes with gear three (740). The top of the inner wall of the mixing tank (1) is slidably connected to a baffle plate (746), and a rack two (744) is fixed on the surface of the baffle plate (746). The top of the inner wall of the mixing tank (1) is rotatably connected to a gear five (745), which meshes with the gear ring (743), and the rack two (744) meshes with the gear five (745).
3. The concentration device for small volume injection production according to claim 2, wherein The baffle (746) is an arc-shaped plate that protrudes from the center of the mixing tank (1) toward the inner wall of the mixing tank (1).
4. The concentration device for producing a small volume injection according to claim 2 or 3, wherein The surface of the spoiler (746) has perforations.
5. The concentration device for small volume injection production according to claim 1, wherein The stirring assembly (6) includes a motor (60), which is fixed to the top of the stirring tank (1). A gear (61) is fixed to the top of the output shaft of the motor (60). A rotating rod (63) is provided on the surface of the stirring tank (1). The rotating rod (63) passes through the stirring tank (1) and is rotatably connected to the stirring tank (1). A gear (62) is fixed to the top of the rotating rod (63). The gear (61) meshes with the gear (62). A stirring rod (64) is fixed to the surface of the rotating rod (63).
6. A concentration device for small volume injection production according to claim 1, characterized in that: The bottom of the mixing tank (1) is fixed with a solenoid valve (5), the discharge port (4) is connected to the mixing tank (1) through the solenoid valve (5), and a heating plate (2) is installed on the outer surface of the mixing tank (1).