A vaccine microcarrier recovery filter with a clean structure

Abstract

This utility model discloses a vaccine microcarrier recovery filter with a clean structure, including a workbench. A cleaning tank is located at the top of the workbench, and a first water tap is located at one end of the cleaning tank. A water storage tank is located at the bottom of the workbench. A filter groove is formed on the inner wall of the workbench, and a filter is movably installed in the filter groove. This utility model achieves automatic rotational cleaning of the filter through the cooperation of a linear motor and a waterproof motor. This dynamic cleaning method is more efficient than static cleaning, and can more thoroughly remove cell debris, culture medium residues, and microbial contamination from the filter surface, ensuring the cleanliness and effectiveness of the filter.

Description

Technical Field

[0001] This utility model relates to the field of microcarrier filter technology, specifically a vaccine microcarrier recovery filter with a clean structure. Background Technology

[0002] Microcarrier technology is widely used in vaccine production, primarily for cell culture and bioreactor operation. These microcarriers provide a surface for cell attachment and growth, thereby facilitating the efficient production of bioproducts such as vaccines. However, at the end of the production cycle, the microcarriers, along with their attached cells, culture media, and other impurities, need to be effectively recovered and disposed of to avoid cross-contamination and ensure the cleanliness of the production environment.

[0003] While existing microcarrier recovery filters play a role in vaccine production, they present significant challenges in terms of cleaning and maintenance. Specifically, the surface of microcarriers may be covered with a large amount of cell debris, culture medium residues, and potential microbial contamination. These impurities can easily clog the micropores of the filter during filtration, leading to decreased filtration efficiency and even affecting the quality of subsequent production batches.

[0004] In addition, traditional cleaning methods such as manual rinsing can remove some impurities, but they are often unable to thoroughly clean the inside of micropores. Incomplete cleaning can easily lead to a decrease in product purity, increasing production risks and costs. Utility Model Content

[0005] (a) Purpose of the utility model

[0006] In view of this, the purpose of this utility model is to provide a vaccine microcarrier recovery filter with a clean structure, which solves the problems mentioned in the background above.

[0007] (II) Technical Solution

[0008] A vaccine microcarrier recovery filter with a clean structure includes a workbench, a cleaning tank at the top of the workbench with a first faucet at one end, a water storage tank at the bottom of the workbench, a filter groove on the inner wall of the workbench with a filter movably installed therein, a cleaning shell fixedly installed at one corner of the inner wall of the cleaning tank with multiple sets of second connecting grooves and a single set of first connecting grooves on the inner wall of the cleaning shell, second connecting pins installed on the inner walls of the multiple sets of second connecting grooves with second cleaning components connected to the tops of the second connecting pins, a first connecting pin movably installed on the inner wall of the first connecting groove with a first cleaning component connected to the top of the first connecting pin, multiple sets of brushes installed on the inner wall of the second cleaning component and the outer surface of the first cleaning component, a support frame fixedly installed on one side of the top of the cleaning tank with a linear motor fixedly installed at one end of the support frame with a waterproof motor connected to one end of the linear motor with a connecting buckle connected to one end of the waterproof motor, a locking groove at the bottom of the filter, and a first drain pipe and a second drain pipe on one side of the workbench and the cleaning tank.

[0009] Preferably, a first faucet and a second faucet are installed on the top outer surface of the cleaning pool.

[0010] Preferably, a limiting ring is fixedly installed at the top of the filter.

[0011] Preferably, a flange is fixedly installed on one side of both the first drain pipe and the second drain pipe.

[0012] Preferably, electronic valves are provided on the outer surfaces of the first drain pipe and the second drain pipe.

[0013] Preferably, the inner wall of the cleaning shell has multiple sets of water outlet grooves.

[0014] Preferably, one end of the support frame is arc-shaped.

[0015] As can be seen from the above technical solutions, this application has the following beneficial effects:

[0016] This invention achieves automatic rotational cleaning of the filter through the combination of a linear motor and a waterproof motor. This dynamic cleaning method is more efficient than static cleaning, and can more thoroughly remove cell debris, culture medium residues, and microbial contamination from the filter surface, ensuring the cleanliness and effectiveness of the filter.

[0017] This invention uses a first and a second cleaning component to clamp the filter, forming an effective cleaning space. Multiple sets of brushes installed on these components can fully cover the outer surface of the filter and the edges of the filter pores. This design ensures comprehensive and thorough cleaning, reducing blind spots. Attached Figure Description

[0018] Figure 1 This is a three-dimensional structural diagram of the present invention;

[0019] Figure 2 This is a schematic diagram of the disassembled structure of this utility model;

[0020] Figure 3 This is a schematic diagram of the cleaning component structure of this utility model;

[0021] Figure 4 This is a schematic diagram of the filter structure of this utility model;

[0022] Figure 5 This is a schematic diagram of the support frame structure of this utility model.

[0023] In the diagram: 1. Workbench; 2. Cleaning tank; 3. First faucet; 4. Filter; 5. Second faucet; 6. First drain pipe; 7. Second drain pipe; 8. Flange; 9. Electronic valve; 911. Cleaning housing; 912. First cleaning component; 913. Second cleaning component; 914. Brush; 915. First connecting pin; 916. Second connecting pin; 611. First connecting groove; 612. Water outlet groove; 613. Second connecting groove; 811. Support frame; 812. Linear motor; 813. Waterproof motor; 814. Connecting buckle; 411. Limiting ring; 412. Engaging groove. Detailed Implementation

[0024] The following description is exemplary in nature and is not intended to limit the scope, application, or use of this disclosure. It should be understood that in all these figures, the same or similar reference numerals indicate the same or similar parts and features. The figures are merely schematic representations of the concept and principles of embodiments of this disclosure and do not necessarily show the specific dimensions and scale of the various embodiments of this disclosure. Certain details or structures of embodiments of this disclosure may be exaggerated in particular portions of certain figures.

[0025] Please see Figure 1-5 One embodiment provided by this utility model:

[0026] A vaccine microcarrier recovery filter with a clean structure includes a workbench 1, a cleaning tank 2 at the top of the workbench 1, a first water tap 3 at one end of the cleaning tank 2, a water storage tank at the bottom of the workbench 1, a filter groove on the inner wall of the workbench 1, a filter 4 movably installed in the filter groove, a cleaning shell 911 fixedly installed at one corner of the inner wall of the cleaning tank 2, and multiple sets of second connecting grooves 613 and a single set of first connecting grooves 611 on the inner wall of the cleaning shell 911, a second connecting pin 916 installed on the inner wall of each of the multiple sets of second connecting grooves 613, and a second cleaning component 913 connected to the top of the second connecting pin 916, and a first connecting pin 915 movably installed on the inner wall of the first connecting groove 611, and the first connecting pin 915... The top of the filter 5 is connected to a first cleaning component 912. Multiple sets of brushes 914 are installed on the inner wall of the second cleaning component 913 and the outer surface of the first cleaning component 912. A support frame 811 is fixedly installed on one side of the top of the cleaning tank 2, and a linear motor 812 is fixedly installed on one end of the support frame 811. The linear motor 812 can directly convert electrical energy into linear motion. A waterproof motor 813 is connected to one end of the linear motor 812. The linear motor 812 drives the waterproof motor 813 to perform linear motion, and a connecting buckle 814 is connected to one end of the waterproof motor 813. A locking groove 412 is opened at the bottom of the filter 4. A first drain pipe 6 and a second drain pipe 7 are opened on one side of the workbench 1 and the cleaning tank 2. The second drain pipe 7 is used to discharge the filtered liquid.

[0027] Furthermore, a first faucet 3 and a second faucet 5 are installed on the top outer surface of the cleaning pool 2. The first faucet 3 and the second faucet 5 can provide different functions or different types of water flow. The first faucet 3 is used for daily cleaning, while the second faucet 5 is used to fill the cleaning shell 911 with water.

[0028] Furthermore, a limiting ring 411 is fixedly installed at the top of the filter 4. The limiting ring 411 can ensure that the filter 4 can be accurately aligned during installation and prevent offset or misalignment.

[0029] Furthermore, flanges 8 are fixedly installed on one side of both the first drain pipe 6 and the second drain pipe 7. The design of flanges 8 makes the pipe connection more secure and reliable, and also facilitates disassembly and maintenance.

[0030] Furthermore, electronic valves 9 are installed on the outer surfaces of the first drain pipe 6 and the second drain pipe 7. The installation of electronic valves 9 enables precise control of the draining process, and the draining speed and flow rate can be adjusted according to actual needs, thereby improving cleaning efficiency.

[0031] Furthermore, the inner wall of the cleaning shell 911 is provided with multiple sets of water outlet grooves 612, which are used for drainage.

[0032] Furthermore, one end of the support frame 811 is arc-shaped, which is designed to reduce friction and collision with the filter or other components, and protect the equipment from damage.

[0033] Working Principle: During the cleaning process of the microcarrier recovery filter for vaccine production, first ensure that the filter 4 has completed its filtration task and is properly placed inside the cleaning shell 911 of the cleaning tank 2. The outer surface of the filter 4 is designed with multiple sets of filter holes, which are used to trap microcarriers, cell debris, and other impurities during normal use, securing the filter 4 inside the cleaning shell 911. At this time, the inner wall of the filter 4 is tightly fitted with the outer surface of the first cleaning component 912, while its outer surface is held by the second cleaning component 913 and the first cleaning component 912, forming an effective cleaning space. Subsequently, the linear motor 812 on the support frame 811 is activated. The extension movement of the linear motor 812 drives the waterproof motor 813 and the connecting buckle 814 at its end to slowly descend. When the connecting buckle 814 descends to a certain position, it will precisely align with the preset engaging groove 412 on the filter 4 and firmly engage, thereby establishing a stable rotational drive connection. Once the connecting buckle 814 is firmly connected to the filter 4, the waterproof motor 813 is activated. The rotational power of the waterproof motor 813 is transmitted to the filter 4 through the connecting buckle 814, causing the filter 4 to rotate at a uniform speed inside the cleaning housing 911. During rotation, the outer surface and filter hole edges of the filter 4 continuously contact the multiple sets of brushes 914 installed on the first cleaning component 912 and the second cleaning component 913. The bristles of the brushes 914 gently and effectively remove cell debris, culture medium residue, and microbial contamination attached to the filter 4. After a period of rotational cleaning, the contaminants on the surface of the filter 4 are effectively removed. At this point, the waterproof motor 813 and the linear motor 812 can be turned off, the connection between the connecting buckle 814 and the filter 4 can be disconnected, and the filter 4 can be removed from the cleaning housing 911 for subsequent inspection or reuse. The second faucet 5 is used to fill the cleaning housing 911 with water and cover the surface of the filter 4. At the same time, the wastewater and impurities generated during the cleaning process pass through the filter holes of the filter 4 and the water outlet 612 of the cleaning housing 911, and are finally discharged from the first drain pipe 6.

[0034] It will be apparent to those skilled in the art that this invention is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this invention. Therefore, the embodiments should be considered illustrative and non-limiting in all respects, and the scope of this invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

Claims

1. A vaccine microcarrier recovery filter with cleaning structure comprising a worktable (1), characterized in that: The top of the workbench (1) is provided with a cleaning pool (2), and one end of the cleaning pool (2) is provided with a first faucet (3). The bottom of the workbench (1) is provided with a water storage tank. The inner wall of the workbench (1) is provided with a filter groove, and a filter (4) is movably installed in the filter groove. A cleaning shell (911) is fixedly installed at one corner of the inner wall of the cleaning pool (2). The inner wall of the cleaning shell (911) is provided with multiple sets of second connecting grooves (613) and a single set of first connecting grooves (611). The inner walls of the multiple sets of second connecting grooves (613) are all provided with second connecting pins (916), and the top of the second connecting pins (916) is connected to a second cleaning component (913). The inner wall of the first connecting groove (611) is movably installed with a first connecting component. A first cleaning component (912) is connected to the top of the first connecting pin (915), and multiple sets of brushes (914) are installed on the inner wall of the second cleaning component (913) and the outer surface of the first cleaning component (912). A support frame (811) is fixedly installed on one side of the top of the cleaning pool (2), and a linear motor (812) is fixedly installed on one end of the support frame (811). A waterproof motor (813) is connected to one end of the linear motor (812), and a connecting buckle (814) is connected to one end of the waterproof motor (813). A locking groove (412) is opened at the bottom of the filter (4). A first drain pipe (6) and a second drain pipe (7) are opened on one side of the workbench (1) and the cleaning pool (2).

2. The vaccine microcarrier recovery filter with a clean structure according to claim 1, characterized in that: The top outer surface of the cleaning pool (2) is equipped with a first faucet (3) and a second faucet (5).

3. The vaccine microcarrier recovery filter with a clean structure according to claim 1, characterized in that: A limiting ring (411) is fixedly installed at the top of the filter (4).

4. A vaccine microcarrier recovery filter with a clean structure according to claim 1, characterized in that: Flanges (8) are fixedly installed on one side of both the first drain pipe (6) and the second drain pipe (7).

5. A vaccine microcarrier recovery filter with a clean structure according to claim 1, characterized in that: Electronic valves (9) are provided on the outer surfaces of the first drain pipe (6) and the second drain pipe (7).

6. A vaccine microcarrier recovery filter with a clean structure according to claim 1, characterized in that: The inner wall of the cleaning shell (911) has multiple sets of water outlet grooves (612).

7. A vaccine microcarrier recovery filter with a clean structure according to claim 1, characterized in that: One end of the support frame (811) is arc-shaped.

Images