Point marking device for corneal suture modeling

Abstract

This utility model relates to the field of animal experimental auxiliary tools, specifically to a point marking device for corneal suture modeling, comprising: an angle adjustment component, including a first rod and a second rod hinged together at their first ends, the first rod and the second rod being rotatable relative to a first axis to change the angle formed between the first rod and the second rod; and an angle fixing rod connected to the second ends of the first rod and the second rod. This utility model is based on a corneal compass with structural improvements. Multiple arc-shaped elastic strips are set on two rods whose relative angle can be changed. By changing the angle between the two rods, the elastic strips can be bent to a curvature matching different corneas. Multiple positioning rods on the elastic strips are in clearly defined relative positions, and the vertical projection of the multiple positioning rods can form multiple clearly defined relative position marking points, ensuring the comparability of modeling results from different experimenters and different batches of animals.

Description

Technical Field

[0001] This utility model relates to the field of animal experimental auxiliary tools, and more specifically to a point marking device for corneal suture modeling. Background Technology

[0002] The cornea, located at the front of the eyeball, is a transparent, avascular, arc-shaped tissue. When the cornea is injured, infected by bacteria or viruses, or suffers from hypoxia due to prolonged contact lens wear, abnormal blood vessel proliferation may occur, leading to eye discomfort, decreased vision, and in severe cases, blindness. Globally, the incidence of corneal neovascularization-related pathological changes is approximately 4.1%–10.4%, with 12%–57.4% of patients experiencing blindness as a result. Traditional hormones and nonsteroidal anti-inflammatory drugs (NSAIDs) have drawbacks such as short duration of action and significant side effects. This particular case is related to inflammatory responses or post-traumatic repair mechanisms. Therefore, studying the formation mechanism and process of corneal neovascularization is of significant clinical importance for developing effective preventive and therapeutic drugs.

[0003] Establishing corneal neovascularization models is crucial for studying its pathogenesis, screening potential therapeutic drugs, and validating treatment methods. Commonly used modeling methods include physical induction, chemical induction, and corneal capsular insertion of inducing agents. Among these, the corneal suture method, as a physical method for inducing corneal neovascularization, is favored by researchers due to its simplicity, ease of observation, and measurement of neovascularization area. Furthermore, compared to chemical methods, the corneal suture method avoids interference from the use of chemicals during modeling, thus better reflecting clinical practice.

[0004] During corneal suture modeling, marking points need to be determined on the surface of the cornea. Subsequent suture modeling determines the suture position based on the marked points. When marking the points, the traditional operation method usually uses a corneal compass and a marking ruler. Due to the large number of points, modeling a single eye takes about 8 to 10 minutes. Moreover, due to the strong subjectivity of manual operation, it is easy to cause large errors in the position and distance of the marking points, which affects the consistency and accuracy of the surgery.

[0005] Therefore, this traditional method is not only time-consuming and inefficient, but may also negatively affect the repeatability and reliability of experimental results, making it difficult to meet the needs of large-scale experiments or high-precision research. Utility Model Content

[0006] To address the technical problems existing in corneal risk marking procedures in the prior art, this utility model proposes a point marking device for corneal suture modeling, comprising:

[0007] An angle adjustment component includes a first rod and a second rod hinged together at their first ends. The first rod and the second rod can rotate relative to a first axis to change the angle formed between the first rod and the second rod.

[0008] An angle fixing rod is connected to the second end of the first rod and the second rod, and is used to limit the angle formed between the first rod and the second rod to the target angle;

[0009] Multiple elastic strips, each elastic strip having a first end connected to the first rod and a second end connected to the second rod, and the intersection of each elastic strip with the first rod and the second rod being located on a circle centered on a first axis;

[0010] Multiple positioning rods are connected to a portion of the elastic strip, each positioning rod being individually slidable relative to the elastic strip along a first axis;

[0011] The lower end of the positioning rod is configured to form a visible mark on the surface of the cornea. When the first rod and the second rod rotate relative to each other, the curvature of each elastic strip changes accordingly to match different corneal curvatures. The projection of the multiple positioning rods along the first axis direction forms multiple target mark points with relatively fixed spacing and position on the corneal surface.

[0012] Preferably, the hinged end of the angle fixing rod is hinged to the second end of the second rod body, the free end of the angle fixing rod is slidably connected to the second end of the first rod body, and the free end of the angle fixing rod is provided with a positioning component to restrict the rotation of the first rod body relative to the second rod body.

[0013] Preferably, the second end of the first rod is provided with a sliding sleeve that can rotate around the first axis. The sliding sleeve has a through hole in the middle, and the free end of the angle fixing rod passes through the through hole and can slide relative to the sliding sleeve.

[0014] Preferably, a first elastic strip, a second elastic strip, a third elastic strip, and a fourth elastic strip are respectively provided between the first rod and the second rod;

[0015] The first elastic strip has no positioning rods, the second elastic strip has four positioning rods, the third elastic strip has four positioning rods, and the fourth elastic strip has two positioning rods.

[0016] Preferably, the distance between the first elastic strip and the second elastic strip is L1, the distance between the second elastic strip and the third elastic strip is L2, and the distance between the third elastic strip and the fourth elastic strip is L3, wherein L1 = L2 = L3.

[0017] Preferably, L1 = L2 = L3 = 1.5 mm.

[0018] Preferably, all the positioning rods are symmetrically distributed on both sides of the angle bisector of the angle formed by the first rod and the second rod.

[0019] Preferably, the second, third, and fourth elastic strips are each provided with positioning holes, and the positioning rod is interference-fitted with the positioning holes.

[0020] Preferably, the positioning rod is configured to include a core layer and a covering layer, wherein the core layer is a rigid structure and the covering layer is an elastic layer.

[0021] Preferably, the positioning rod includes a rod body, a first spherical structure located at the upper end of the rod body, and a second spherical structure located at the lower end of the rod body.

[0022] Compared with the prior art, the advantages of this utility model are:

[0023] This invention improves upon the structure of a corneal compass by incorporating multiple arc-shaped elastic strips on two rods with adjustable relative angles. By changing the angle between the two rods, the elastic strips can bend to a curvature that matches different corneas. Multiple positioning rods on the elastic strips are in clearly defined relative positions. When the device is positioned above the eyeball, the vertical projections of these positioning rods form multiple clearly defined relative markers. By moving the positioning rods along the height direction to their positions against the corneal surface, the corneal surface is marked. This marking method reduces the time required from 8-10 minutes to 1-2 minutes while maintaining consistency. It offers high marking accuracy, ensuring comparability of results from different experimenters and animal batches, and reducing the interference of human error in drug evaluation. Attached Figure Description

[0024] The accompanying drawings are not intended to be drawn to scale. In the drawings, each identical or nearly identical component shown in the various figures may be denoted by the same reference numeral. For clarity, not every component is labeled in each figure. Embodiments of various aspects of the present invention will now be described by way of example and with reference to the accompanying drawings, wherein:

[0025] Figure 1 This is a schematic diagram of the point marking device for corneal suture modeling shown in this utility model;

[0026] Figure 2 This is a schematic diagram of the point marking device for corneal suture modeling shown in this utility model, which is set above the cornea;

[0027] Figure 3 This is a schematic diagram showing the distribution of the multiple positioning rods as illustrated in this utility model;

[0028] Figure 4This is a schematic diagram of the positioning rod shown in this utility model;

[0029] Figure 5 This is a schematic diagram showing how multiple positioning rods form marking points on the corneal surface, as illustrated in this utility model. Detailed Implementation

[0030] To better understand the technical content of this utility model, specific embodiments are provided below in conjunction with the accompanying drawings.

[0031] Combination Figure 1 As shown, this utility model proposes a point marking device for corneal suture modeling, including an angle adjustment component 10, an angle fixing rod 20, multiple elastic strips 30 and multiple positioning rods 40.

[0032] Because rabbits have similar anterior segment structure and ocular surface area to humans, and are easy to administer drugs and observe, they are often chosen as research subjects for modeling. Corneal suture manipulation is an in vivo experiment. Therefore, the marking device is placed above the rabbit's eye during use, and the suture points are marked by multiple positioning rods 40 on the device.

[0033] like Figure 1 As shown, the angle adjustment component 10 includes a first rod 11 and a second rod 12 hinged together at their first ends. The first rod 11 and the second rod 12 can rotate relative to a first axis to change the angle formed between the first rod 11 and the second rod 12.

[0034] It should be understood that the first ends of the first rod 11 and the second rod 12 intersect to form an angle. The greater the distance between the first rod 11 and the second rod 12, the larger the angle formed; the smaller the distance between them, the smaller the angle formed. Optionally, the angle formed between the first rod 11 and the second rod 12 is between 60 degrees and 120 degrees.

[0035] Furthermore, the angle fixing rod 20 is connected to the second end of the first rod 11 and the second rod 12 to limit the angle formed between the first rod 11 and the second rod 12 to the target angle.

[0036] That is, the angle between the first rod 11 and the second rod 12 can be fixed to a certain position by means of the angle fixing rod 20, so that the angle formed between the first rod 11 and the second rod 12 will not change during the process of determining the point.

[0037] In an optional embodiment, the hinged end 21 of the angle fixing rod 20 is hinged to the second end of the second rod 12, and the free end 22 of the angle fixing rod 20 is slidably connected to the second end of the first rod 11. The free end 22 of the angle fixing rod 20 is provided with a positioning component 23 for restricting the rotation of the first rod 11 relative to the second rod 12.

[0038] Specifically, the second end of the first rod 11 is provided with a sliding sleeve that can rotate around the first axis. The sliding sleeve has a through hole in the middle. The free end 22 of the angle fixing rod 20 passes through the through hole and can slide relative to the sliding sleeve.

[0039] The positioning component 23 includes a nut, and the free end 22 of the fixing rod 20 is threaded. When the nut is rotated, the position of the nut at the free end 22 is slightly adjusted, so that the angle between the first rod 11 and the second rod 12 changes. After the angle is properly adjusted, the first rod 11 is positioned by the compression of the elastic strip 30 (which tends to push the first rod 11 to the right) in conjunction with the nut (which restricts the first rod from moving to the right).

[0040] Furthermore, the first end of each of the plurality of elastic strips 30 is connected to the first rod 11, and the second end is connected to the second rod 12, and the intersection of each elastic strip 30 with the first rod 11 and the second rod 12 is located on a circle with the first axis as the center.

[0041] Thus, the center of the curved trajectory formed by all the elastic bars 30 is located at the same point, namely the intersection of the first rod 11 and the second rod 12.

[0042] Furthermore, multiple positioning rods 40 are connected to a portion of the elastic strip 30, and each positioning rod 40 can slide individually relative to the elastic strip 30 along a first axis. Thus, each positioning rod 40 is operable to slide along the first axis until the bottom end of the positioning rod 40 contacts the surface of the cornea, forming a marking point on the corneal surface.

[0043] The lower end of the positioning rod 40 is configured to form a visible mark on the surface of the cornea. When the first rod 11 and the second rod 12 rotate relative to each other, the curvature of each elastic strip 30 changes accordingly to match different corneal curvatures.

[0044] For example, changes in eyeball volume caused by different experimental subjects can be addressed by adjusting the angles of the first rod 11 and the second rod 12 to match the curvature of the elastic strip 30 with that of the cornea.

[0045] Furthermore, the projections of multiple positioning rods 40 along the first axis direction form multiple target marker points with relatively fixed spacing and position on the corneal surface.

[0046] In this way, multiple target markers can be formed at predetermined locations on the surface of the cornea according to experimental needs, and in particular, the consistency of repeated operations can be guaranteed.

[0047] It should be understood that sutures need to penetrate the corneal stroma to a certain depth in order to effectively stimulate the inflammatory response and neovascularization. By setting markers, it can be ensured that each suture is inserted into a precise position on a pre-set circular trajectory around the center of the cornea. This positional consistency ensures experimental consistency and comparability between different rabbits and between different experimental groups of the same rabbit, thereby improving experimental results.

[0048] like Figure 1 As shown, a first elastic strip 31, a second elastic strip 32, a third elastic strip 33 and a fourth elastic strip 34 are respectively provided between the first rod 11 and the second rod 12.

[0049] The first elastic strip 31 has no positioning rods 40, the second elastic strip 32 has four positioning rods 40, the third elastic strip 33 has four positioning rods 40, and the fourth elastic strip 34 has two positioning rods 40.

[0050] Thus, ten positioning marks are formed by the four positioning rods 40 on the second elastic strip 32, the four positioning rods 40 on the third elastic strip 33, and the two positioning rods 40 on the fourth elastic strip 34. All the positioning rods 40 are symmetrically distributed on both sides of the angle bisector of the angle formed by the first rod 11 and the second rod 12.

[0051] like Figure 1 and Figure 2 As shown, with the foremost point of the cornea 100 as the 12 o'clock position, and the 12 o'clock position as the dividing line, five positioning rods 40 are set on each side. The distance between the two positioning rods 40 at the center of the second elastic strip 32 is LA, and the distance between the two positioning rods 40 on both sides and the positioning rod 40 at the center is LB. The distance between the two positioning rods 40 at the center of the third elastic strip 33 is La, and the distance between the two positioning rods 40 on both sides and the marking point at the center is Lb. The distance between the two positioning rods 40 on the fourth elastic strip 34 is LC.

[0052] In an optional embodiment, the distance between the first elastic strip 31 and the second elastic strip 32 is L1, the distance between the second elastic strip 32 and the third elastic strip 33 is L2, and the distance between the third elastic strip 33 and the fourth elastic strip 34 is L3, wherein L1 = L2 = L3.

[0053] In a preferred embodiment, L1 = L2 = L3 = 1.5 mm, LA = La = 0.5 ~ 1.0 mm, LB = 3.8 mm, Lb = 3.0 mm, and LC = 2.0 mm.

[0054] Such a distribution of suture points can create a denser network of sutures with more irritation points in specific areas around the cornea.

[0055] Combination Figures 3 to 5 As shown, the second elastic strip 32, the third elastic strip 33 and the fourth elastic strip 34 are all provided with positioning holes 301, and the positioning rod 40 is interference-fitted with the positioning holes 301.

[0056] It should be understood that, in the case of an interference fit, the diameter of the positioning rod 40 is slightly larger than the inner diameter of the positioning hole 301.

[0057] In this way, the positioning rod 40 can move up or down under the user's operation, so that its bottom contacts the corneal surface to form a marking point, and the positioning rod 40 and the positioning hole 301 can be used to prevent the positioning rod 40 from falling down on its own.

[0058] Optionally, the positioning rod 40 is configured to include a core layer and a covering layer, wherein the core layer is a rigid structure and the covering layer is an elastic layer.

[0059] The core layer can be made of iron wire, and the covering layer can be made of rubber or silicone.

[0060] By constructing an elastically deformable structure, the positioning rod 40 has a better damping effect when moving in the positioning hole 301.

[0061] In an optional embodiment, the positioning rod 40 includes a rod body 41, a first spherical structure 42 located at the upper end of the rod body 41, and a second spherical structure 43 located at the lower end of the rod body 41. Optionally, the first spherical structure 42 and the second spherical structure 43 are made of silicone.

[0062] The first spherical structure 42 has a volume of approximately 2-3 mm and is used by the user to pinch and control the movement of the lever 41. The second spherical structure 43 is slightly smaller and its bottom tip is narrowed to about 0.5 mm. The second spherical structure 43 can pick up pigment and form a marking point of about 0.5 mm on the surface of the cornea when it comes into contact with the cornea.

[0063] In specific embodiments, such as Figure 5 As shown, after anesthetizing the experimental subject, the eyeball can be fixed with an eyelid speculum. After the second spherical structure 43 is dipped in pigment, the entire device is placed above the eyeball. Then, the angles of the first rod 11 and the second rod 12 are adjusted until the curvature of the first elastic strip 31 matches that of the corneal edge, so that the gap between the four positioning rods 40 in the center of the device is aligned with the 12 o'clock position. Then, each positioning rod 40 is moved downward until the second spherical structure 43 at the bottom of the positioning rod 40 forms a mark point 102 with a diameter of about 0.5 mm on the corneal surface. In this way, by giving preset parameters for the relative position of each positioning rod 40, the reproducibility of batch experiments can be guaranteed.

[0064] Although the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the present invention. Those skilled in the art to which this invention pertains can make various modifications and refinements without departing from the spirit and scope of the present invention. Therefore, the scope of protection of this invention shall be determined by the claims.

Claims

1. A point marking device for corneal suture modeling, characterized by, include: Angle adjustment component (10) includes a first rod (11) and a second rod (12) hinged together at their first ends. The first rod (11) and the second rod (12) can rotate relative to a first axis to change the angle formed between the first rod (11) and the second rod (12). An angle fixing rod (20) is connected to the second end of the first rod (11) and the second rod (12) to limit the angle formed between the first rod (11) and the second rod (12) to the target angle. Multiple elastic strips (30), each elastic strip (30) having a first end connected to the first rod (11) and a second end connected to the second rod (12), and the intersection of each elastic strip (30) with the first rod (11) and the second rod (12) being located on a circle centered on a first axis; Multiple positioning rods (40) are connected to a portion of the elastic strip (30), each positioning rod (40) being individually slidable relative to the elastic strip (30) along a first axis; The lower end of the positioning rod (40) is configured to form a visible mark on the surface of the cornea. When the first rod (11) and the second rod (12) rotate relative to each other, the curvature of each elastic strip (30) changes accordingly to match different corneal curvatures. The projection of the multiple positioning rods (40) along the first axis direction forms multiple target mark points with relatively fixed spacing and position on the corneal surface.

2. The point marking device for corneal suture templating of claim 1, wherein, The hinge end (21) of the angle fixing rod (20) is hinged to the second end of the second rod body (12), and the free end (22) of the angle fixing rod (20) is slidably connected to the second end of the first rod body (11). The free end (22) of the angle fixing rod (20) is provided with a positioning component (23) for restricting the rotation of the first rod body (11) relative to the second rod body (12).

3. The point marking device for corneal suture modeling according to claim 2, characterized in that, The second end of the first rod (11) is provided with a sliding sleeve that can rotate around the first axis. The sliding sleeve has a through hole in the middle. The free end (22) of the angle fixing rod (20) passes through the through hole and can slide relative to the sliding sleeve.

4. The point marking device for corneal suture templating of claim 1, wherein, A first elastic strip (31), a second elastic strip (32), a third elastic strip (33), and a fourth elastic strip (34) are respectively provided between the first rod (11) and the second rod (12); The first elastic strip (31) has no positioning rods (40), the second elastic strip (32) has four positioning rods (40), the third elastic strip (33) has four positioning rods (40), and the fourth elastic strip (34) has two positioning rods (40).

5. The point marking device for corneal suture templating of claim 4, wherein, The distance between the first elastic strip (31) and the second elastic strip (32) is L1, the distance between the second elastic strip (32) and the third elastic strip (33) is L2, and the distance between the third elastic strip (33) and the fourth elastic strip (34) is L3, wherein L1 = L2 = L3.

6. The point marking device for corneal suture templating of claim 5, wherein, L1 = L2 = L3 = 1.5 mm.

7. The point marking device for corneal suture templating of claim 1, wherein, All of the positioning rods (40) are symmetrically distributed on both sides of the angle bisector of the angle formed by the first rod (11) and the second rod (12).

8. The point marking device for corneal suture templating of claim 4, wherein, The second elastic strip (32), the third elastic strip (33) and the fourth elastic strip (34) are all provided with positioning holes (301), and the positioning rod (40) is interference-fitted with the positioning holes (301).

9. The point marking device for corneal suture templating of claim 8, wherein, The positioning rod (40) is configured to include a core layer and a covering layer, wherein the core layer is a rigid structure and the covering layer is an elastic layer.

10. The point marking device for corneal suture modeling according to claim 1, characterized in that, The positioning rod (40) includes a rod body (41), a first spherical structure (42) located at the upper end of the rod body (41), and a second spherical structure (43) located at the lower end of the rod body (41).

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