A device for the comminution of proteinaceous substances
By using a dual cooling method—a water-cooled jacket on the outer wall of the hammer crusher and the introduction of cooling air—the problems of heat accumulation and impurity contamination during the crushing of protein substances are solved, achieving efficient and safe crushing results. This method is suitable for the production of Class III implantable medical devices.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- SHANDONG JUNXIU BIOTECHNOLOGY CO LTD
- Filing Date
- 2025-08-26
- Publication Date
- 2026-07-24
AI Technical Summary
During the pulverization of protein-based substances, heat accumulation causes the material temperature to rise, making it prone to denaturation. Existing freezing methods pose a risk of impurity contamination and are costly, making it difficult to meet the cleanroom production requirements for Class III implantable medical devices.
A water-cooled jacket and cooling air are installed on the outer wall of the hammer crusher. The dual cooling method of cooling water and cooling air prevents heat accumulation, avoids impurities from mixing into the material, and ensures temperature control during the crushing process.
It achieves efficient pulverization in a clean area, with the material temperature not exceeding 50℃ and a material yield of up to 95%, avoiding impurity contamination and safety risks, and meeting the national standard Class 1 cleanroom standard.
Smart Images

Figure CN224541902U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of pulverizing devices, and in particular to a device for pulverizing protein-based substances. Background Technology
[0002] Some Class III implantable medical devices use protein-based materials as raw materials, which require a pulverization process to meet specified specifications. This pulverization process generates significant heat as the material changes form. If this heat is allowed to accumulate, the material temperature will rise, causing the protein to denature, turn yellow, or even become pasty. Currently, liquid nitrogen is commonly used to cool the material during pulverization. However, liquid nitrogen contains impurities such as oil, water, particles, and microorganisms, increasing the risk of contamination when mixed with the raw materials, making it unsuitable for Class III implantable medical device production. Furthermore, liquid nitrogen products with fully controlled impurities are too expensive for large-scale material handling. Additionally, excessively low temperatures in liquid nitrogen can increase safety risks for operators. Summary of the Invention
[0003] To address the shortcomings of existing technologies, the purpose of this invention is to provide a device for pulverizing protein-based substances. This device features a water-cooled jacket on the outer wall of the hammer-blade pulverizer and introduces cooling air into the pulverizer. This prevents heat accumulation during the pulverizing process while avoiding the mixing of other impurities with the pulverized material. It can solve the production problems of pulverizing processes within the cleanroom of Class III implantable medical devices.
[0004] To achieve the above objectives, this utility model is implemented through the following technical solution: This utility model provides a device for pulverizing protein-based substances, including a hammer crusher. The hammer crusher is provided with a feed inlet and a discharge outlet. The feed inlet is connected to a feeding device, and the discharge outlet is connected in sequence to a receiving bin and a dust collector. The outer wall of the hammer crusher is provided with a jacket, the jacket is provided with a cooling water outlet and a cooling water inlet, and the hammer crusher is provided with a cooling air inlet that penetrates the outer wall.
[0005] Optionally, the feeding device includes a feeding chamber and a feeding valve. The feeding chamber is used to temporarily store the material to be crushed, and the feeding valve is used to control the speed at which the material to be crushed enters the hammer crushing device.
[0006] Optionally, the hammer crushing device is provided with a hammer shaft, which is connected to a drive motor; the drive motor is located outside the hammer crushing device.
[0007] Optionally, the dust collector is connected to a vortex blower; the vortex blower is used to provide negative pressure for the hammer crushing device and its connected receiving hopper and dust collector, so as to facilitate the transfer and collection of materials.
[0008] Optionally, the interlayer is provided with multiple partitions to divide the interlayer into multiple horizontal channels, which are connected to form tortuous water-cooled pipes, and the water-cooled pipes are respectively connected to the cooling water outlet and the cooling water inlet.
[0009] Optionally, the cooling water outlet is positioned higher than the cooling water inlet, and the cooling water flows through the water-cooling pipe in an upward direction to cool the hammer crusher.
[0010] Optionally, the cooling water outlet and cooling water inlet are respectively connected to a cooling water cooling circulation device, which is used to cool down the cooling water output from the interlayer that has become too hot and then send it back to the interlayer.
[0011] Optionally, the outer wall of the hammer crusher is provided with a jacket, and the jackets of different outer walls are independent of each other to improve the circulation efficiency of cooling water.
[0012] Optionally, the front wall of the hammer crusher is provided with a front wall interlayer, and the rear wall is provided with a rear wall interlayer.
[0013] Optionally, the cooling air inlet is connected to a clean pre-cooled compressed air source, which is used to provide dry, clean compressed air to the hammer crusher and to cool the compressed air to -50~-10℃ before delivery; further, the pressure of the compressed air is 0.4~0.6 MPa.
[0014] Optionally, a gas distribution device is provided on the side of the cooling air inlet facing the inside of the hammer crusher, which is used to evenly distribute air to the material and the mechanical structure including the hammer. The gas distribution device is set inside the dustproof net to prevent the crushed material from entering the clean pre-cooled compressed air source and its pipeline in reverse during the start-up or shutdown of the device.
[0015] The beneficial effects of this utility model are as follows: 1. This utility model provides a device for pulverizing protein-based materials, which includes a cooling water outlet / inlet for water cooling and a cooling air inlet for air cooling. The contact components with the material in the hammer pulverizer mainly consist of an outer wall and hammer blades. The outer wall is fitted with a jacket and cooled by flowing cooling water, while the hammer blades are cooled by direct blowing of cooling air. This dual cooling method effectively prevents heat accumulation in the device and prevents the material from overheating. It also avoids the introduction of other contaminants and minimizes safety risks during operation.
[0016] 2. The device of this utility model can continuously crush protein substances up to 0.1-10 kg, and the particle size of the crushed material can reach 0.1-4 mm. The temperature of the crushed and sieved material does not exceed 50℃, and the material yield is >95%. Since the device of this utility model is set in the clean area of the workshop, and the clean pre-cooled compressed air introduced also meets the national standard level 1, the introduced impurities will not affect the product quality. Attached Figure Description
[0017] The accompanying drawings, which form part of this specification, are used to provide a further understanding of this utility model. The illustrative embodiments of this utility model and their descriptions are used to explain this utility model and do not constitute an improper limitation of this utility model.
[0018] The diagram exaggerates the spacing or dimensions between parts to show their positions; the diagram is for illustrative purposes only.
[0019] Figure 1 This is a schematic diagram of the device used for pulverizing protein substances in a specific embodiment.
[0020] Figure 2 This is a schematic diagram of the hammer crushing device in a specific embodiment.
[0021] Figure 3 This is a schematic diagram of the internal structure of the outer wall interlayer of the hammer crusher in a specific embodiment.
[0022] The components include: 1. Feeding chamber; 2. Feeding valve; 3. Hammer crushing device; 4. Drive motor; 5. Receiving bin; 6. Dust collector; 7. Vortex fan; 8. Front wall interlayer; 9. Rear wall interlayer; 10. Cooling water outlet; 11. Cooling water inlet; 14. Cooling air inlet; and 15. Baffle. Detailed Implementation
[0023] The present invention will be further described below with reference to the accompanying drawings and embodiments.
[0024] A device for pulverizing protein-based materials includes a water-cooled jacket on the outer wall of the hammer pulverizer and cooling air introduced into the hammer pulverizer. This prevents heat accumulation during the pulverization process while avoiding the mixing of other substances with the pulverized material, and can solve the production problem of pulverization in the clean area of Class III implantable medical devices.
[0025] A device for pulverizing protein-based substances, such as Figure 1 As shown, it includes a hammer crushing device 3, which is provided with a feed inlet and a discharge outlet. The feed inlet is connected to a feeding device, and the discharge outlet is connected in sequence to a receiving bin 5 and a dust collector 6. like Figure 2As shown, the outer wall of the hammer crusher 3 is provided with a jacket, and the jacket is provided with a cooling water outlet 10 and a cooling water inlet 11. The hammer crusher 3 is provided with a cooling air inlet 14 that penetrates the outer wall.
[0026] In the above structure, the hammer crusher 3 is cooled by cooling water flowing in the jacket, and cooling air is introduced into the hammer crusher 3 through the cooling air inlet 14 to mix with the material, which plays a role in cooling the inside of the hammer crusher 3. In particular, the cooling air also has a fluidization effect, which can prevent the crushed material from accumulating in the corners of the hammer crusher 3 or on the hammer blades, keeping both the material and the crushing device at a low temperature, and preventing the material from denaturing due to temperature rise.
[0027] The feeding device includes a feeding chamber 1 and a feeding valve 2, wherein the feeding valve 2 is selected as a butterfly valve.
[0028] The hammer crushing device 3 is equipped with a hammer shaft, which is connected to the drive motor 4 on the outside of the hammer crushing device 3. The drive motor 4 is installed in an explosion-proof box for independent protection to improve the safety of the device operation.
[0029] Dust collector 6 is connected to vortex blower 7. Vortex blower 7 generates negative pressure, which guides the flow of cooling air and causes the crushed material to transfer to the receiving bin 5. Excessively fine material or material dust enters dust collector 6 and is collected, thereby improving the material yield of the entire crushing process.
[0030] like Figure 3 As shown, the outer wall interlayer is provided with multiple partitions 15, which divide the outer wall interlayer into multiple horizontal channels. The multiple channels are connected to form a tortuous water-cooled pipeline. The two ends of the water-cooled pipeline are connected to the cooling water outlet 10 and the cooling water inlet 11, respectively. This tortuous water-cooled pipeline makes the flow direction of the incoming cooling water fixed and can quickly discharge the water after heat exchange, thereby improving the heat exchange efficiency and the cooling effect of the equipment.
[0031] If the cooling water outlet 10 is higher than the cooling water inlet 11, the cooling water in the water-cooled pipeline flows from bottom to top. Inside the hammer crusher 3, the hammer is located in the middle of the device. As the cooling water flows from bottom to top, it gradually heats up and can quickly cool areas where heat is concentrated.
[0032] Cooling water outlet 10 and cooling water inlet 11 are respectively connected to the cooling water cooling circulation device outside the whole device, which is used to cool down the cooling water output from the jacket and then send it back to the jacket.
[0033] The hammer crusher 3 has a cylindrical structure, with the hammer shaft installed at the central axis. The two bottom surfaces of the cylindrical structure are the front and rear walls of the hammer crusher 3, respectively. Since the front and rear walls of the hammer crusher 3 have large areas, interlayers are provided in both walls. Figure 2 As shown, the front wall of the hammer crusher 3 is provided with a front wall interlayer 8, and the rear wall is provided with a rear wall interlayer 9. The front wall interlayer 8 and the rear wall interlayer 9 are independent of each other and are provided with their own cooling water outlet 10 and cooling water inlet 11.
[0034] The cooling air inlet 14 is connected to a clean pre-cooled compressed air source. The compressed air source provides dry and clean compressed air, which is then cooled and delivered into the hammer crusher 3. During the crushing process, the clean pre-cooled compressed air is mixed with the material for cooling. After heat exchange, the air is drawn away by the negative pressure generated by the vortex blower 7 along with the material, further removing the heat inside the crusher. The cooling air can also blow away the material deposited in the corners of the crusher or on the hammer blades, and together with the vortex blower 7, promote the conveying of the material.
[0035] A gas distribution device is provided on the side of the cooling air inlet 14 facing the inside of the hammer crusher 3. This device is used to evenly distribute air to the material and the mechanical structure, including the hammer, to ensure that the cooling air inside the hammer crusher 3 is evenly distributed. The gas distribution device is also located inside the dustproof net as a safety measure to prevent the crushed material from entering the clean pre-cooled compressed air source and its pipeline in reverse during the start-up or shutdown of the device.
[0036] During the material crushing process, the vortex blower 7 continuously provides negative pressure to the crushing chamber of the hammer crusher 3 to collect and transfer the material. The pressure of the compressed air source introduced through the cooling air inlet 14 is about 0.4-0.6 MPa, which is much higher than the pressure inside the crushing device. Therefore, during the operation of the device, the crushed material will not be sucked back into the pipeline connected to the cooling air inlet 14. When the device stops running, the drive motor 4 is turned off first, and the vortex blower 7 continues to run for a period of time to remove as much material as possible from the crushing chamber and prevent the material from being sucked back into the air path.
[0037] The above description is merely a preferred embodiment of this application and is not intended to limit this application. Various modifications and variations can be made to this application by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the protection scope of this application.
Claims
1. An apparatus for pulverizing protein-based substances, characterized in that, The device includes a hammer crusher, which has a feed inlet and a discharge outlet. The feed inlet is connected to a feeding device, and the discharge outlet is connected in sequence to a receiving hopper and a dust collector. The outer wall of the hammer crusher is provided with a jacket, which has a cooling water outlet and a cooling water inlet. The hammer crusher is also provided with a cooling air inlet that penetrates the outer wall.
2. The apparatus for pulverizing protein-based substances as described in claim 1, characterized in that, The feeding device includes a feeding chamber and a feeding valve.
3. The apparatus for pulverizing protein-based substances as described in claim 1, characterized in that, The hammer crushing device is equipped with a hammer shaft, which is connected to a drive motor.
4. The apparatus for pulverizing protein-based substances as described in claim 1, characterized in that, The dust collector is connected to a vortex blower.
5. The apparatus for pulverizing protein-based substances as described in claim 1, characterized in that, The outer wall of the hammer crusher is provided with a double layer, and the double layers of the outer wall are independent of each other.
6. The apparatus for pulverizing protein-based substances as described in claim 5, characterized in that, The hammer crushing device has a front wall interlayer on its front wall and a rear wall interlayer on its rear wall.
7. The apparatus for pulverizing protein-based substances as described in claim 1, characterized in that, The interlayer is provided with multiple partitions, which divide the interlayer into multiple horizontal channels. The multiple channels are connected to form a tortuous water-cooling pipeline, which is connected to the cooling water outlet and the cooling water inlet respectively.
8. The apparatus for pulverizing protein-based substances as described in claim 7, characterized in that, The cooling water outlet is located higher than the cooling water inlet; the cooling water outlet and the cooling water inlet are respectively connected to a cooling water cooling circulation device.
9. The apparatus for pulverizing protein-based substances as described in claim 1, characterized in that, The cooling air inlet is connected to a clean pre-cooled compressed air source.
10. The apparatus for pulverizing protein-based substances as described in claim 1, characterized in that, A gas distribution device is provided on the side of the cooling air inlet facing the inside of the hammer crusher, and the gas distribution device is located inside the dustproof net.