A cell disruption device for biological gene detection

Abstract

The utility model discloses a kind of cell crushing devices for biological gene detection, it is related to cell crushing technical field, including crushing box, the front surface of crushing box is equipped with box door, hinged joint is connected between the box door and crushing box, the bottom of crushing box is fixedly connected with multiple supporting feet, and the top of crushing box is embedded with operating panel, the middle position of box door is embedded with visual window, the inside of crushing box is fixedly connected with ultrasonic generator near top position, the bottom of ultrasonic generator is connected with conducting rod, the inner surface of crushing box is connected with auxiliary positioning structure.The utility model said a kind of cell crushing devices for biological gene detection, can be positioned to the position of beaker loaded with cell liquid, can be adjusted to the appropriate position, can ensure the accuracy of cell crushing position, can be conveniently supported to the placement seat after adjustment, can improve the relative stability of cell crushing device work.

Description

Technical Field

[0001] This utility model relates to the field of cell disruption technology, and in particular to a cell disruption device for biological gene detection. Background Technology

[0002] With the development of science and technology, people have gradually begun to delve into the field of biology. Research in the field of biology requires a comprehensive understanding of the cells that make up living organisms. The first step in understanding cells is to break them down to understand their components. Cell disruption generally requires the use of ultrasonic disruption methods.

[0003] Chinese patent CN215996995U discloses a cell disruption device for biological gene detection, including an operating box. The operating box has a movably mounted door at its front end, a disruption groove on its inner side, a controller fixedly mounted at its top, a receiving plate on its inner side, and an ultrasonic module fixedly mounted near the top of the inner side. A transmission rod is fixedly mounted at the bottom of the ultrasonic module. A motor is fixedly mounted on the inner side of the operating box, and a connecting plate is driven to the outer side of the motor. A cleaning ring is fixedly mounted at one end of the connecting plate, and expansion cotton is fixedly mounted on the inner side of the cleaning ring. This enables cleaning of the outer side of the transmission rod, solving the problem of residual solution on the outer side of the transmission rod after cell disruption, which is inconvenient to clean due to the transmission rod being located inside the device. This facilitates the post-processing of the device.

[0004] Traditional cell disruption devices for biological gene detection cannot accurately position the beaker containing cell fluid during use. Insufficient beaker height can prevent the cell fluid from making contact with the ultrasonic transducer, affecting the accuracy of cell disruption. Furthermore, the lack of support after adjustment can compromise the relative stability of the cell disruption device. Utility Model Content

[0005] The main objective of this invention is to provide a cell disruption device for biological gene detection, which can effectively solve the problems mentioned in the background art. Traditional cell disruption devices for biological gene detection cannot accurately position the beaker containing cell fluid during use. Insufficient beaker height can lead to the cell fluid not making contact with the ultrasonic transmission rod, affecting the accuracy of cell disruption. Furthermore, the lack of support after adjustment can affect the relative stability of the cell disruption device.

[0006] To achieve the above objectives, the technical solution adopted by this utility model is as follows:

[0007] A cell disruption device for biological gene detection includes a disruption chamber, a door fitted onto the front surface of the disruption chamber, a hinge connecting the door to the disruption chamber, multiple support legs fixedly connected to the bottom of the disruption chamber, an operation panel embedded in the top of the disruption chamber, a viewing window embedded in the middle of the door, an ultrasonic generator fixedly connected to the inside of the disruption chamber near the top, a transmission rod connected to the bottom of the ultrasonic generator, and an auxiliary positioning structure connected to the inner surface of the disruption chamber.

[0008] As a further embodiment of this utility model, the auxiliary positioning structure includes a guide seat, a placement seat, a lifting frame, and a placement groove. The guide seat is fixed to the inner surface of the crushing box, the placement seat is disposed inside the guide seat, the lifting frame is fixed to the end of the guide seat, and the placement groove is opened on the upper surface of the placement seat.

[0009] As a further embodiment of this utility model, a slide rail is fixedly installed on the outer surface of the lifting frame, a slide groove is provided on the outer surface of the placement seat, the slide rail is adapted to the slide groove, and a recessed part adapted to the placement seat is provided on the inner side of the guide seat.

[0010] As a further embodiment of this utility model, the placement seat is slidably connected to the lifting frame via a slide rail and a slide groove, and the placement seat and the lifting frame are arranged perpendicular to each other.

[0011] As a further embodiment of this utility model, a guide frame is fixedly connected to the inner surface of the crushing box, a sliding seat is engaged at the top of the guide frame, and a support frame is fixedly connected to the top of the sliding seat.

[0012] As a further embodiment of this utility model, a lifting frame is fixedly connected to the top of the support frame, and a connecting frame is fixedly connected to the bottom of the support frame. The support frame is movably connected to the guide frame through a sliding seat.

[0013] The beneficial effects of this utility model are as follows: by setting an auxiliary positioning structure, it is convenient to position the beaker containing cell fluid, and the beaker can be adjusted to a suitable position to ensure the accuracy of the cell breakage position.

[0014] By setting up guide frames, support frames, and lifting frames, the adjusted placement seat can be easily supported, which can improve the relative stability of the cell disruption device. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the overall structure of a cell disruption device for biological gene detection according to this utility model;

[0016] Figure 2 This is a schematic diagram of the internal structure of the cell disruption chamber of a cell disruption device for biological gene detection according to this utility model;

[0017] Figure 3 This is a schematic diagram of the auxiliary positioning structure of a cell disruption device for biological gene detection according to the present invention;

[0018] Figure 4 This is a schematic diagram showing the connection of the guide frame, support frame, and lifting frame of a cell disruption device for biological gene detection according to this utility model.

[0019] In the diagram: 1. Crushing box; 2. Box door; 3. Hinge; 4. Support leg; 5. Control panel; 6. Viewing window; 7. Ultrasonic generator; 8. Transmission rod; 9. Auxiliary positioning structure; 10. Guide seat; 11. Placement seat; 12. Lifting frame; 13. Placement slot; 14. Slide rail; 15. Slide groove; 16. Guide frame; 17. Sliding seat; 18. Support frame; 19. Lifting frame; 20. Connecting frame. Detailed Implementation

[0020] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0021] Example 1

[0022] Combination Figures 1-4 A cell disruption device for biological gene detection includes a disruption chamber 1, a door 2 attached to the front surface of the disruption chamber 1, a hinge 3 connecting the door 2 and the disruption chamber 1, multiple support feet 4 fixedly connected to the bottom of the disruption chamber 1, an operation panel 5 embedded in the top of the disruption chamber 1, a viewing window 6 embedded in the middle of the door 2, an ultrasonic generator 7 fixedly connected to the inside of the disruption chamber 1 near the top, a transmission rod 8 connected to the bottom of the ultrasonic generator 7, and an auxiliary positioning structure 9 connected to the inner surface of the disruption chamber 1.

[0023] See Figure 1 and Figure 3 Furthermore, the auxiliary positioning structure 9 includes a guide seat 10, a placement seat 11, a lifting frame 12, and a placement groove 13. The guide seat 10 is fixed to the inner surface of the crushing box 1, the placement seat 11 is disposed inside the guide seat 10, the lifting frame 12 is fixed to the end of the guide seat 10, and the placement groove 13 is opened on the upper surface of the placement seat 11.

[0024] Specifically, the beaker containing cell solution is placed into the placement slot 13 of the placement seat 11, and the placement seat 11 is pushed. The lifting frame 12 limits the horizontal position of the placement seat 11 and positions the beaker containing cell solution. This allows the beaker to be adjusted to a suitable position, ensuring the accuracy of cell disruption.

[0025] See Figure 2 and Figure 3 Furthermore, the outer surface of the lifting frame 12 is fixedly equipped with a slide rail 14, the outer surface of the placement seat 11 is provided with a slide groove 15, the slide rail 14 is adapted to the slide groove 15, the inner side of the guide seat 10 is provided with a recess that is adapted to the placement seat 11, the placement seat 11 is slidably connected to the lifting frame 12 through the slide rail 14 and the slide groove 15, and the placement seat 11 and the lifting frame 12 are arranged perpendicular to each other.

[0026] Specifically, by lifting the placement seat 11, which slides relative to the lifting frame 12 via the slide rail 14 and the slide groove 15, the beaker on the placement seat 11 can be lifted to ensure that the cell fluid in the beaker comes into contact with the conduction rod 8.

[0027] Example 2

[0028] See Figure 1 and Figure 4 Furthermore, based on Embodiment 1, the inner surface of the crushing box 1 is fixedly connected to a guide frame 16, the top of the guide frame 16 is fitted with a sliding seat 17, the top of the sliding seat 17 is fixedly connected to a support frame 18, the top of the support frame 18 is fixedly connected to a lifting frame 19, and the bottom of the support frame 18 is fixedly connected to a connecting frame 20. The support frame 18 is movably connected to the guide frame 16 through the sliding seat 17.

[0029] Specifically, the support frame 18 is pushed, and the support frame 18 moves relative to the guide frame 16 through the sliding seat 17. The connecting frame 20 can prevent the support frame 18 from tipping over. The support frame 18 drives the lifting frame 19 to lift the bottom of the placement seat 11, which facilitates the support of the adjusted placement seat 11.

[0030] It should be noted that this utility model is a cell disruption device for biological gene detection. In use, pulling the door 2 causes it to move relative to the disruption chamber 1 via the hinge 3. A beaker containing cell solution is placed into the placement groove 13 of the placement seat 11. Pushing the placement seat 11 causes the lifting frame 12 to limit its horizontal position and position the beaker containing cell solution. This allows the beaker to be adjusted to a suitable position, ensuring the accuracy of cell disruption. Lifting the placement seat 11 allows it to slide relative to the lifting frame 12 via the slide rail 14 and slide groove 15, which can... The beaker on the movable placement seat 11 is lifted to ensure that the cell fluid in the beaker comes into contact with the conduction rod 8, pushing the support frame 18. The support frame 18 moves relative to the guide frame 16 through the sliding seat 17. The connecting frame 20 can prevent the support frame 18 from tipping over. The support frame 18 drives the lifting frame 19 to lift the bottom of the placement seat 11, which facilitates the support of the adjusted placement seat 11. The ultrasonic generator 7 is started. The ultrasonic generator 7 works and disperses in the cell fluid through the conduction rod 8, causing the cell fluid to produce cavitation, thereby breaking down solid particles and cell tissues in the liquid.

[0031] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model.

Claims

1. A cell disruption device for biological gene detection, comprising a disruption chamber (1), characterized in that: The front surface of the crushing box (1) is fitted with a door (2), and the door (2) is connected to the crushing box (1) by a hinge (3). The bottom of the crushing box (1) is fixedly connected with multiple support feet (4), and the top of the crushing box (1) is fitted with an operation panel (5). The middle position of the door (2) is fitted with a viewing window (6). The inside of the crushing box (1) is fixedly connected to an ultrasonic generator (7) near the top position. The bottom of the ultrasonic generator (7) is connected with a transmission rod (8), and the inner surface of the crushing box (1) is connected with an auxiliary positioning structure (9).

2. The cell disruption device for biological gene detection according to claim 1, characterized in that: The auxiliary positioning structure (9) includes a guide seat (10), a placement seat (11), a lifting frame (12), and a placement groove (13). The guide seat (10) is fixed to the inner surface of the crushing box (1). The placement seat (11) is located inside the guide seat (10). The lifting frame (12) is fixed to the end of the guide seat (10). The placement groove (13) is opened on the upper surface of the placement seat (11).

3. The cell disruption device for biological gene detection according to claim 2, characterized in that: The outer surface of the lifting frame (12) is fixedly equipped with a slide rail (14), and the outer surface of the placement seat (11) is provided with a slide groove (15). The slide rail (14) is adapted to the slide groove (15), and the inner side of the guide seat (10) is provided with a recess that is adapted to the placement seat (11).

4. The cell disruption device for biological gene detection according to claim 3, characterized in that: The placement seat (11) is slidably connected to the lifting frame (12) via a slide rail (14) and a slide groove (15), and the placement seat (11) and the lifting frame (12) are arranged perpendicular to each other.

5. The cell disruption device for biological gene detection according to claim 1, characterized in that: The inner surface of the crushing box (1) is fixedly connected to a guide frame (16), and a sliding seat (17) is fixedly mounted on the top of the guide frame (16). A support frame (18) is fixedly connected to the top of the sliding seat (17).

6. The cell disruption device for biological gene detection according to claim 5, characterized in that: The top of the support frame (18) is fixedly connected to a lifting frame (19), and the bottom of the support frame (18) is fixedly connected to a connecting frame (20). The support frame (18) is movably connected to the guide frame (16) through a sliding seat (17).

Images