An analytical titration apparatus for pharmaceutical testing

Abstract

The utility model discloses a kind of analysis titration devices for drug testing, it is related to drug testing equipment technical field, including titration mechanism and conical flask, the bottom end of titration mechanism is fixedly installed with shake even mechanism, the utility model is by setting shake even mechanism, shake even motor drives support plate fast rotation, to make card seat and conical flask fast rotation, while miniature rotating motor drives eccentric wheel rotation, eccentric wheel and reset spring two combination, realize that card seat and conical flask can be horizontal direction and do fast reciprocating motion, make conical flask can horizontal direction and do fast reciprocating motion while fast rotation, to shake and even in conical flask solution, after titration, the solution can be quickly shaken and even by the device, and shake even effect is better, it is convenient for operator to be more accurately carried out drug testing analysis, so that operator can be focused on observing the color change of titration process, it is convenient for actual use.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical testing equipment technology, and in particular to an analytical titration device for pharmaceutical testing. Background Technology

[0002] There are numerous testing items in pharmaceutical testing, including pharmaceutical quality testing, pharmaceutical component testing, pharmaceutical heavy metal testing, pharmaceutical adverse reaction testing, pharmaceutical sealing testing, biological drug testing, pharmaceutical appearance testing, routine pharmaceutical testing, pharmaceutical physicochemical testing, pharmaceutical safety testing, and pharmaceutical defect testing. Pharmaceutical testing usually uses titration for quantitative analysis. Titration is a quantitative analysis method and a chemical experimental operation. It determines the content of a certain solute through the quantitative reaction of two solutions. It uses the color change of an indicator to indicate the titration endpoint, then visually measures the volume of standard solution consumed, and calculates the analytical results.

[0003] For example, Chinese patent CN213715150U discloses an analytical titration device for pharmaceutical testing, including an operating table, a clamping plate, and a fixing ring. The upper surface of the clamping plate is provided with a sliding groove, and a first sliding rod and a second sliding rod are slidably connected inside the sliding groove. A first fixing frame and a second fixing frame are sleeved on the surface of the first sliding rod. A telescopic rod is provided on one side of the first fixing frame, and a connecting rod is hinged to one end of the telescopic rod. A fixing cylinder is provided at the bottom of one end of the connecting rod.

[0004] Existing titration apparatuses for pharmaceutical testing and analysis typically require the operator to hold the burette in one hand and the conical flask containing the solution to be titrated in the other, shaking the flask continuously during titration. This process prevents the operator from focusing on observing the color changes during titration, and the manual shaking does not allow for rapid and thorough mixing of the titrated solution. These existing apparatuses not only increase manpower but are also time-consuming and inefficient, making them impractical for real-world use. To address these issues, a new analytical titration apparatus for pharmaceutical testing is proposed. Utility Model Content

[0005] The purpose of this invention is to solve the problems existing in the prior art by proposing an analytical titration device for pharmaceutical testing.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: an analytical titration device for pharmaceutical testing, comprising a titration mechanism and a conical flask. A shaking mechanism is fixedly installed at the bottom of the titration mechanism. The shaking mechanism includes a base, a support plate, a shaking motor, a clamping seat, a micro-rotating motor, and an eccentric wheel. The top of the shaking motor is fixedly installed at the top of the base, and the output end of the shaking motor is fixedly connected to the bottom of the support plate. A baffle is fixedly connected to one top end of the support plate, and a fixing block is fixedly connected to the other top end of the support plate. The top of the clamping seat is engaged with the bottom of the conical flask. A connecting rod is sleeved on the top of the fixing block. Two extension plates are symmetrically fixedly connected to both ends of the clamping seat. The bottoms of the two extension plates are slidably connected to the top of the support plate. A second return spring is fixedly connected to one end of one extension plate, and a first end of the other extension plate is fixedly installed to one end of the connecting rod. A push wheel is fixedly connected to the other end of the connecting rod. The output end of the micro-rotating motor is fixedly connected to one end of the eccentric wheel, and one end of the second return spring is fixedly connected to one end of the baffle.

[0007] Preferably, the top of the base has a groove, and the bottom end of the support plate is movably connected to the groove.

[0008] Preferably, the titration mechanism includes a support frame, a movable rod, a fixed plate, and two burettes, with the top end of the fixed plate rotatably mounted to the top end of the support frame.

[0009] Preferably, the top of the fixed plate is fixedly connected to the bottom of the movable rod, and two connecting rods are symmetrically sleeved at both ends of the fixed plate.

[0010] Preferably, a pressure block is fixedly installed on the top of the connecting rod, a servo push rod is fixedly connected to the top of the support frame, and the bottom of the support frame is fixedly installed to the bottom of the base.

[0011] Preferably, a set spring is symmetrically fixedly connected to both ends of the top of the fixed plate, and the top of the set spring is fixedly connected to the bottom of the pressure block.

[0012] Preferably, the top of the burette is snapped into the bottom of the connecting rod, and a knob is fixedly connected to the bottom of the burette, and a titration tip is fixedly connected to the bottom of the knob.

[0013] Compared with the prior art, the advantages and positive effects of this utility model are as follows:

[0014] 1. In this utility model, by setting a shaking mechanism, the shaking motor drives the support plate to rotate rapidly, thereby causing the card holder and the conical flask to rotate rapidly. At the same time, the micro-rotating motor drives the eccentric wheel to rotate. The eccentric wheel and the return spring work together to enable the card holder and the conical flask to make rapid reciprocating motion in the horizontal direction. This allows the conical flask to make rapid reciprocating motion in the horizontal direction while rotating rapidly, thereby shaking and mixing the solution in the conical flask. This device can quickly shake the titrated solution, and the shaking effect is better, making it easier for operators to perform drug testing and analysis more accurately.

[0015] 2. In this utility model, by setting a shaking mechanism, the operator does not need to manually shake the solution after titration, which saves time and effort and is highly efficient. This allows the operator to focus on observing the color change during the titration process, making it convenient for practical use. Attached Figure Description

[0016] Figure 1 This utility model provides a three-dimensional structural schematic diagram of an analytical titration device for pharmaceutical testing;

[0017] Figure 2 This utility model provides a schematic diagram of the rear structure of an analytical titration device for pharmaceutical testing;

[0018] Figure 3 This utility model provides a schematic diagram of the shaking mechanism of an analytical titration device for pharmaceutical testing;

[0019] Figure 4 The present invention provides a bottom view of the burette structure of an analytical titration device for pharmaceutical testing.

[0020] Legend: 1. Titration mechanism; 2. Shaking mechanism; 3. Conical flask; 10. Knob; 11. Support frame; 12. Servo push rod; 13. Movable rod; 14. Fixed plate; 15. Pressure block; 16. Return spring one; 17. Connecting rod; 18. Burette; 19. Titration end; 21. Base; 22. Groove; 23. Support plate; 24. Extension plate; 25. Shaking motor; 26. Baffle; 27. Return spring two; 28. Card holder; 29. ​​Miniature rotating motor; 210. Eccentric wheel; 211. Push wheel; 212. Connecting rod; 213. Fixed block. Detailed Implementation

[0021] To better understand the above-mentioned objectives, features, and advantages of this utility model, the present utility model will be further described below with reference to the accompanying drawings and embodiments. It should be noted that, unless otherwise specified, the embodiments and features described in these embodiments can be combined with each other.

[0022] Many specific details are set forth in the following description in order to provide a full understanding of the present invention. However, the present invention may also be implemented in other ways different from those described herein. Therefore, the present invention is not limited to the specific embodiments disclosed in the following specification.

[0023] Example 1: As Figure 1 - Figure 3 As shown, this utility model provides an analytical titration device for pharmaceutical testing, including a titration mechanism 1 and a conical flask 3. A shaking mechanism 2 is fixedly installed at the bottom of the titration mechanism 1. The shaking mechanism 2 includes a base 21, a support plate 23, a shaking motor 25, a retainer 28, a micro rotary motor 29, and an eccentric wheel 210. The top of the shaking motor 25 is fixedly installed at the top of the base 21, and the output end of the shaking motor 25 is fixedly connected to the bottom of the support plate 23. A baffle 26 is fixedly connected to one end of the top of the support plate 23, and a fixing block 213 is fixedly connected to the other end of the top of the support plate 23. The top of the retainer 28 is engaged with the bottom of the conical flask 3. A connecting rod 212 is sleeved on the top of 213. Two extension plates 24 are symmetrically fixedly connected to both ends of the card seat 28. The bottom of both extension plates 24 are slidably connected to the top of the support plate 23. One end of one extension plate 24 is fixedly connected to a return spring 27. One end of the other extension plate 24 is fixedly installed to one end of the connecting rod 212. The other end of the connecting rod 212 is fixedly connected to a push wheel 211. The output end of the micro rotating motor 29 is fixedly connected to one end of the eccentric wheel 210. One end of the return spring 27 is fixedly connected to one end of the baffle 26. The top of the base 21 has a groove 22, and the bottom end of the support plate 23 is movably connected to the groove 22.

[0024] The specific settings and functions of this embodiment are described below: The operator turns on the micro rotary motor 29 and the shaking motor 25, and simultaneously presses the knob 10 to make the liquid in the burette 18 drip down into the conical flask 3 at a rate of 3-4 drops per second. The shaking motor 25 drives the support plate 23 to rotate rapidly, thereby causing the holder 28 and the conical flask 3 to rotate rapidly, shaking the liquid in the conical flask 3. At the same time, the micro rotary motor 29 drives the eccentric wheel 210 to rotate. The outer wall of the eccentric wheel 210 is in contact with the outer wall of the push wheel 211. The eccentric wheel 210 and the return spring 27 work together to enable the holder 28 and the conical flask 3 to make rapid reciprocating motion in the horizontal direction. Therefore, the conical flask 3 can make rapid reciprocating motion in the horizontal direction while rotating rapidly, thereby shaking and mixing the solution in the conical flask 3. This device can quickly shake the titrated solution, and the shaking effect is better.

[0025] Example 2: Figure 1 , Figure 2 and Figure 4As shown, this utility model provides an analytical titration apparatus for pharmaceutical testing, including a titration mechanism 1 and a conical flask 3. A shaking mechanism 2 is fixedly installed at the bottom end of the titration mechanism 1. The titration mechanism 1 includes a support frame 11, a movable rod 13, a fixed plate 14, and two burettes 18. The top end of the fixed plate 14 is rotatably installed with the top end of the support frame 11. The top end of the fixed plate 14 is fixedly connected to the bottom end of the movable rod 13, and two connecting rods 17 are symmetrically sleeved at both ends of the fixed plate 14. A pressure block 15 is fixedly installed on the top. A servo push rod 12 is fixedly connected to the top of the support frame 11, and the bottom of the support frame 11 is fixedly installed to the bottom of the base 21. A return spring 16 is symmetrically fixedly connected to both ends of the top of the fixing plate 14. The top of the return spring 16 is fixedly connected to the bottom of the pressure block 15. The top of the burette 18 is snapped into the bottom of the connecting rod 17. A knob 10 is fixedly connected to the bottom of the burette 18, and a titration end 19 is fixedly connected to the bottom of the knob 10.

[0026] The overall effect of this embodiment is as follows: The conical flask 3 is placed on top of the holder 28, so that the bottom of the conical flask 3 is locked and fixed to the holder 28. The operator rotates the movable rod 13, so that the burette 18 is positioned at the top of the conical flask 3. At this time, the servo push rod 12 is activated, pressing down on the pressure block 15. The pressure block 15, connecting rod 17, and burette 18 move downwards, thereby causing the titration tip 19 to move downwards and insert into the conical flask 3. At this time, the operator activates the micro-rotating motor 29 and the shaking motor 25, causing the conical flask to... While the conical flask 3 rotates rapidly, it can also make rapid reciprocating motion in the horizontal direction. The operator observes the color of the solution in the conical flask 3. After the titration is completed, the knob 10 is turned off, and the solution in the burette 18 stops dripping downwards. The servo push rod 12 is turned off, and the pressure block 15 and the connecting rod 17 automatically return to their original positions under the action of the return spring 16. The titration end 19 is removed from the conical flask 3. The movable rod 13 is rotated so that the other burette 18 is located at the top of the conical flask 3. The above operation is repeated to perform the titration.

[0027] The operating method and working principle of this device are as follows: When using this device for drug titration analysis, first place the conical flask 3 on top of the holder 28, so that the bottom of the conical flask 3 is locked in place with the holder 28. The operator rotates the movable rod 13 to position the burette 18 at the top of the conical flask 3. At this time, the servo push rod 12 is activated, and the servo push rod 12 presses down on the pressure block 15. The pressure block 15, the connecting rod 17, and the burette 18 move downward, thereby moving the titration tip 19 downward and inserting it into the conical flask 3 (1 cm). (At a position of ~2cm), the operator turns on the micro rotary motor 29 and the shaking motor 25, and simultaneously presses the knob 10 to make the liquid in the burette 18 drip down into the conical flask 3 at a rate of 3~4 drops per second. The shaking motor 25 drives the support plate 23 to rotate rapidly, thereby causing the holder 28 and the conical flask 3 to rotate rapidly, shaking the medicine in the conical flask 3. At the same time, the micro rotary motor 29 drives the eccentric wheel 210 to rotate, and the outer wall of the eccentric wheel 210 is in contact with the outer wall of the push wheel 211. Figure 3 As shown, when the eccentric wheel 210 rotates, the push wheel 211 and the connecting rod 212 can move along the fixed block 213, thereby pushing the extension plate 24 and causing the card holder 28 to move towards the return spring 27. The card holder 28 squeezes the return spring 27, the eccentric wheel 210 continues to rotate, and the return spring 27 releases elastic potential energy, thereby causing the card holder 28 and the connecting rod 212 to move and return to their original positions. The return spring 27 realizes the reset function. The micro-rotation motor 29 drives the eccentric wheel 210 to rotate. The eccentric wheel 210 and the return spring 27 are combined to enable the card holder 28 and the conical flask 3 to make rapid reciprocating motion in the horizontal direction. Therefore, the conical flask 3 can make rapid reciprocating motion in the horizontal direction while rotating rapidly, thereby shaking and mixing the solution in the conical flask 3. This device can quickly shake the titrated solution, and the shaking effect is better, which makes it easier for operators to perform drug testing and analysis more accurately.

[0028] Meanwhile, by setting up a shaking mechanism 2, the operator does not need to manually shake the titrated solution, which saves time and effort and is highly efficient. This allows the operator to focus on observing the color change during the titration process, making it convenient for practical use.

[0029] The operator observes the color of the solution in the conical flask 3. After the titration is completed, the knob 10 is turned off, and the solution in the burette 18 stops dripping. The servo push rod 12 is turned off, and the pressure block 15 and the connecting rod 17 automatically return to their original positions under the action of the return spring 16. The titration end 19 is removed from the conical flask 3. The movable rod 13 is rotated to position the other burette 18 at the top of the conical flask 3. The above operation is repeated to perform the titration.

[0030] The above description is merely a preferred embodiment of the present utility model and is not intended to limit the present utility model in any other way. Any person skilled in the art may make changes or modifications to the above-disclosed technical content to create equivalent embodiments for application in other fields. However, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present utility model without departing from the technical solution of the present utility model shall still fall within the protection scope of the present utility model.

Claims

1. An analytical titration apparatus for pharmaceutical testing, comprising a titration mechanism (1) and an conical flask (3), characterized in that: The bottom end of the titration mechanism (1) is fixedly installed with a shaking mechanism (2). The shaking mechanism (2) includes a base (21), a support plate (23), a shaking motor (25), a clamp (28), a micro rotating motor (29), and an eccentric wheel (210). The top end of the shaking motor (25) is fixedly installed with the top end of the base (21), and the output end of the shaking motor (25) is fixedly connected to the bottom of the support plate (23). A baffle (26) is fixedly connected to one end of the top of the support plate (23), and a fixing block (213) is fixedly connected to the other end of the top of the support plate (23). The top of the clamp (28) is clamped to the bottom of the conical flask (3). A connecting rod (212) is sleeved on the top of the fixed block (213). Two extension plates (24) are symmetrically fixedly connected to both ends of the card seat (28). The bottom of the two extension plates (24) is slidably connected to the top of the support plate (23). One end of one extension plate (24) is fixedly connected to a second return spring (27). One end of the other extension plate (24) is fixedly installed to one end of the connecting rod (212). The other end of the connecting rod (212) is fixedly connected to a push wheel (211). The output end of the micro rotating motor (29) is fixedly connected to one end of the eccentric wheel (210). One end of the second return spring (27) is fixedly connected to one end of the baffle (26).

2. The analytical titration apparatus for pharmaceutical testing according to claim 1, characterized in that: The base (21) has a groove (22) on its top, and the bottom end of the support plate (23) is movably connected to the groove (22).

3. The analytical titration apparatus for pharmaceutical testing according to claim 1, characterized in that: The titration mechanism (1) includes a support frame (11), a movable rod (13), a fixed plate (14) and two burettes (18), with the top of the fixed plate (14) rotatably mounted to the top of the support frame (11).

4. The analytical titration apparatus for pharmaceutical testing according to claim 3, characterized in that: The top of the fixed plate (14) is fixedly connected to the bottom of the movable rod (13), and two connecting rods (17) are symmetrically sleeved at both ends of the fixed plate (14).

5. The analytical titration apparatus for pharmaceutical testing according to claim 4, characterized in that: A pressure block (15) is fixedly installed on the top of the connecting rod (17), a servo push rod (12) is fixedly connected to the top of the support frame (11), and the bottom end of the support frame (11) is fixedly installed to the bottom of the base (21).

6. The analytical titration apparatus for pharmaceutical testing according to claim 3, characterized in that: The top two ends of the fixed plate (14) are symmetrically fixedly connected with a reset spring (16), and the top of the reset spring (16) is fixedly connected to the bottom of the pressure block (15).

7. The analytical titration apparatus for pharmaceutical testing according to claim 3, characterized in that: The top of the burette (18) is engaged with the bottom of the connecting rod (17), and a knob (10) is fixedly connected to the bottom of the burette (18), and a titration end (19) is fixedly connected to the bottom of the knob (10).

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