Temperature-controllable magnetic stirring automatic derivatization reaction device

Abstract

The utility model discloses a controllable temperature formula magnetic force stirring automatic derivative reaction device, including digital display base, the upper end surface of digital display base is provided with reaction mechanism, and reaction mechanism is used for magnetic force stirring mixed liquid sample, and reaction mechanism includes the reaction kettle of digital display base upper end surface setting, and one side of reaction kettle is provided with drainage mechanism, and drainage mechanism is used for the drainage inside reaction kettle, and drainage mechanism includes the drainage pipe of reaction kettle one side setting, and the upper end outside of drainage pipe has the fixed ring of sticking, and the one side of fixed ring is connected with the bayonet pin, and the bayonet pin has the support block of clamping, and the bayonet pin is driven to separate the clamping support block restraint through the fixed ring to the removal of the upward movement, and the end of drainage pipe is aimed at wastewater storage barrel, and the inside liquid of reaction kettle is conveniently discharged, and the design of derivative pipe frame can store multiple centrifugal tubes simultaneously, is suitable for carrying out large quantities of derivative reaction simultaneously and is used, and the design of reaction kettle cover can reduce the volatilization of organic derivative solvent, reduces environmental pollution, and protects the experimental personnel.

Description

Technical Field

[0001] This utility model relates to the technical field of laboratory analytical equipment, specifically a temperature-controlled magnetic stirring automatic derivatization reaction device. Background Technology

[0002] Chemical derivatization refers to the transformation of specific functional groups in a target compound through a specific chemical reaction, generating a substance with a similar chemical structure. Appropriate derivatization reactions can alter the properties of compounds, enhance their stability, improve the separation of complex mixtures, and effectively increase the sensitivity and accuracy of difficult-to-analyze substances in instruments.

[0003] Derivatization reactions require the addition of a certain amount of derivatizing reagent and the material to be derived to a magnetic stirrer, followed by timed stirring in a reaction vessel at a specific temperature. Derivatization reactions often require large-scale simultaneous reactions. If only small-scale reactions can be carried out each time, repeated setups are necessary, which is time-consuming, labor-intensive, and affects parallelism. Currently, most derivatizing reagents, depending on their chemical properties, require various conditions during the reaction, such as protection from water and light, and airtight sealing. Furthermore, both the reagents themselves and their solvents are toxic, and improper handling can lead to decomposition and volatilization, affecting reaction efficiency, toxicity to laboratory personnel, and environmental pollution.

[0004] With the widespread application of derivatization reactions, some derivatization devices have been developed. However, existing derivatization devices are relatively simple, unable to adapt to various reaction temperatures by changing the external reaction medium, lacking dedicated temperature probes, and their temperature control performance needs improvement. The fixed installation of the heating device and digital display base inside the reaction vessel with the magnetic stirrer makes it inconvenient to drain media such as water and silicone oil from the reaction vessel, and also hinders internal cleaning and maintenance. The number of magnetic stirring points is insufficient to ensure complete reaction in each reaction tube. Furthermore, the reaction vessel can only hold a limited number of centrifuge tubes, typically 2-4 at a time, making it inconvenient for simultaneous large-scale derivatization reactions, and repeated exposure of the derivatizing reagents to air can easily lead to oxidation and decomposition, affecting reaction efficiency. Finally, most derivatization devices lack timing devices, yet controlling the derivatization reaction time is crucial; excessively long derivatization times result in incomplete derivatization and are prone to side reactions. Therefore, improvements to existing technologies are necessary. Utility Model Content

[0005] The purpose of this invention is to provide a temperature-controlled magnetic stirring automatic derivatization reaction device to solve the problems existing in the prior art.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a temperature-controlled magnetic stirring automatic derivatization reaction device, wherein a timing alarm device is provided inside the digital display base, and a reaction mechanism is provided on the upper surface of the digital display base. The reaction mechanism is used for magnetic stirring of mixed liquid samples, and the reaction mechanism includes a reaction pot provided on the upper surface of the digital display base.

[0007] A drainage mechanism is provided on one side of the reaction vessel. The drainage mechanism is used to drain water from the inside of the reaction vessel. The drainage mechanism includes a drain pipe provided on one side of the reaction vessel. A fixing ring is glued to the outer side of the upper end of the drain pipe. A locking pin is connected to one side of the fixing ring. The locking pin is engaged with a support block.

[0008] The reaction vessel is equipped with a heating mechanism for heating liquid samples. The heating mechanism includes a heating ring inside the reaction vessel and a temperature probe inside one side of the reaction vessel.

[0009] The reaction vessel is equipped with a frame mechanism inside, which is used to store liquid sample devices. The frame mechanism includes a derivatization tube rack inside the reaction vessel. Handles are symmetrically arranged on both sides of the derivatization tube rack, and centrifuge tubes are sleeved inside the derivatization tube rack.

[0010] The upper end of the reaction vessel is provided with a cover mechanism, which is used to shield light and prevent contamination. The cover mechanism includes a reaction vessel lid with a retaining sleeve at the upper end of the reaction vessel, and a handle is provided on the upper surface of the reaction vessel lid.

[0011] Preferably, a magnetic stir bar is fitted inside the centrifuge tube, and a control mechanism is provided on one side of the digital display base. The control mechanism is used to control the digital display base switch. The control mechanism includes a display screen provided on one side of the digital display base, a magnetic stirring switch provided on one side of the digital display base, and a power switch provided on one side of the digital display base.

[0012] Preferably, the digital display base is equipped with a magnetic drive device inside, and the lower end of one side of the heating ring is connected to the inside of the digital display base.

[0013] Preferably, the reactor is fitted with a handle inside and a centrifuge tube inside.

[0014] Preferably, a support block is provided on one side of the reaction vessel, and a centrifuge tube is sleeved inside the heating ring.

[0015] Compared with the prior art, the beneficial effects of this utility model are:

[0016] This temperature-controlled, magnetically stirred, automatic derivatization reaction apparatus uses an upward-moving fixing ring to disengage a locking pin from the support block, aligning the drain pipe end with the wastewater storage tank for easy drainage of liquid from the reaction vessel. The timing alarm device facilitates accurate control of the reaction time, saving manpower. The derivatization tube rack design allows for simultaneous storage of multiple centrifuge tubes, suitable for large-scale derivatization reactions. The reaction vessel lid design reduces the evaporation of organic derivatizing solvents, minimizing environmental pollution and protecting personnel. It also provides light protection, prevents decomposition of derivatizing reagents, and improves derivatization efficiency. Attached Figure Description

[0017] Figure 1 This is a perspective view of the overall structure of this utility model;

[0018] Figure 2 This is an enlarged cross-sectional view of the reaction vessel of this utility model;

[0019] Figure 3 This is an enlarged perspective view of the fixing ring of this utility model;

[0020] Figure 4 This is an enlarged perspective view of the derivative tube rack of this utility model.

[0021] In the diagram: 1 Digital display base, 11 Reactor, 12 Drain pipe, 13 Fixing ring, 14 Clip, 15 Support block, 16 Heating ring, 17 Temperature probe, 2 Derivative tube rack, 21 Handle, 22 Centrifuge tube, 3 Reactor lid, 31 Handle, 4 Display screen, 41 Magnetic stirring switch, 42 Power switch. Detailed Implementation

[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0023] Please see Figure 1-4 The temperature-controlled magnetic stirring automatic derivatization reaction device shown in the figure includes a digital display base 1. The digital display base 1 is equipped with a timing alarm device inside, which can issue an alarm to facilitate accurate control of the reaction time and save manpower for experimental personnel. The upper end of the digital display base 1 is equipped with a reaction mechanism for magnetic stirring of mixed liquid samples. The reaction mechanism includes a reaction pot 11 set on the upper end of the digital display base 1.

[0024] A drainage mechanism is provided on one side of the reaction vessel 11. The drainage mechanism is used to drain water from the inside of the reaction vessel 11. The drainage mechanism includes a drain pipe 12 provided on one side of the reaction vessel 11. A fixing ring 13 is glued to the outer side of the upper end of the drain pipe 12. A locking pin 14 is connected to one side of the fixing ring 13. The locking pin 14 is engaged with the support block 15.

[0025] The reaction vessel 11 is equipped with a heating mechanism for heating the liquid sample. The heating mechanism includes a heating ring 16 inside the reaction vessel 11 and a temperature probe 17 inside one side of the reaction vessel 11.

[0026] During the experiment, excessively high temperatures may cause reactants to volatilize or decompose, or even lead to safety accidents; excessively low temperatures may slow the reaction rate, affecting experimental efficiency and results. Temperature probe 17 continuously monitors the solution temperature, and the magnetic stirrer can take appropriate measures if the temperature exceeds the set range. When the temperature is too high, the heating system will stop working; when the temperature is too low, the heating power will be increased to ensure the experiment is conducted within a suitable temperature range, improving the safety and reliability of the experiment.

[0027] The reaction vessel 11 has an internal frame mechanism for storing liquid sample devices. The frame mechanism includes a derivatization tube rack 2 inside the reaction vessel 11. Handles 21 are symmetrically arranged on both sides of the derivatization tube rack 2. Centrifuge tubes 22 are connected inside the derivatization tube rack 2.

[0028] The upper end of the reaction vessel 11 is provided with a cover mechanism, which is used to shield light and prevent contamination. The cover mechanism includes a reaction vessel lid 3 with a retaining sleeve at the upper end of the reaction vessel 11, and a handle 31 is provided on the upper surface of the reaction vessel lid 3.

[0029] Magnetic stirrers utilize the properties of magnetic fields—like poles repel and unlike poles attract—to drive a magnetic stir bar by continuously changing the polarity of the base. As the stir bar rotates, it causes the sample to rotate, resulting in uniform mixing. Simultaneously, the magnetic stirrer also features a heating function. A bottom temperature control plate heats the sample, and this, combined with the rotation of the magnetic stir bar, ensures even heating to the specified temperature. Furthermore, the heating power can be adjusted to control the heating rate, making it suitable for a wider range of sample processing procedures.

[0030] When the magnetic drive device is powered on, it generates an alternating magnetic field that passes through the stirring rod and the bottom of the container. Since the stirring rod and the magnet have the same poles facing each other, when the alternating magnetic field passes through, it creates a magnetic field of relative motion between the stirring rod and the magnet, thereby causing the stirring rod to rotate. The rotation of the stirring rod in turn causes the liquid to flow, resulting in a uniform distribution of the solute in the liquid.

[0031] Please see Figure 1 and Figure 2A magnetic stir bar is fitted inside the centrifuge tube 22. A control mechanism is set on one side of the digital display base 1. The control mechanism is used to control the switch of the digital display base 1. The control mechanism includes a display screen 4 set on one side of the digital display base 1, a magnetic stirring switch 41 set on one side of the digital display base 1, and a power switch 42 set on one side of the digital display base 1.

[0032] With this setup, turning on the power switch 42 causes the internal drive device of the digital display base 1 to rotate the magnetic poles continuously, thereby rotating the magnetic stir bar inside the centrifuge tube 22, which facilitates stirring of the sample inside the centrifuge tube 22.

[0033] Please see Figure 1 and Figure 2 A magnetic drive device is installed inside the digital display base 1, and the lower end of one side of the heating ring 16 is connected to the inside of the digital display base 1.

[0034] With this setup, by activating the heating ring 16, the internal heating ring 16 of the reaction vessel 11 can heat the liquid, making it suitable for a wider range of sample processing. The design of the derivatization tube rack 2 can store multiple centrifuge tubes 22 at the same time, making it suitable for simultaneous large-scale derivatization reactions.

[0035] Please see Figure 1 , Figure 3 and Figure 4 The reactor 11 is internally fitted with a handle 21 and a centrifuge tube 22.

[0036] With this setup, the reaction vessel lid 3 can be removed by moving the handle 31 upwards, and the centrifuge tube 22 can be removed by moving the pull handle 21 upwards, so that the reaction vessel 11, the derivatization tube rack 2, and the reaction vessel lid 3 can be cleaned and maintained. The design of the reaction vessel lid 3 can reduce the volatilization of organic derivatization solvents, reduce environmental pollution, and protect experimental personnel.

[0037] Please see Figure 1-3 A support block 15 is provided on one side of the reaction vessel 11, and a centrifuge tube 22 is sleeved inside the heating ring 16.

[0038] With this setup, by moving the fixing ring 13 upward, the locking pin 14 is disengaged from the locking support block 15, and the end of the drain pipe 12 is aligned with the wastewater storage tank, making it convenient to drain the liquid inside the reaction vessel 11.

[0039] The working principle of this embodiment is as follows: When using this temperature-controlled magnetic stirring automatic derivatization reaction device, the power switch 42 is turned on, which causes the internal drive device of the digital display base 1 to drive the magnetic pole to rotate continuously, thereby driving the magnetic stir bar inside the centrifuge tube 22 to rotate, which facilitates the stirring of the sample inside the centrifuge tube 22.

[0040] By activating the heating ring 16, the internal heating ring 16 of the reaction vessel 11 can heat the liquid, making it suitable for a wider range of sample processing. The design of the reaction vessel lid 3 can reduce the volatilization of organic derivatization solvents, reduce environmental pollution, and protect experimental personnel. The design of the derivatization tube rack 2 can store multiple centrifuge tubes 22 at the same time, making it suitable for simultaneous large-scale derivatization reactions.

[0041] By moving the handle 31 upwards, the reaction vessel lid 3 is removed. After removing the centrifuge tube 22, the handle 21 is moved upwards to remove the derivative tube rack 2, so that the reaction vessel 11, derivative tube rack 2 and reaction vessel lid 3 can be cleaned and maintained. By moving the fixing ring 13 upwards, the locking pin 14 is released from the locking support block 15. The end of the drain pipe 12 is aligned with the wastewater storage tank to facilitate the discharge of liquid inside the reaction vessel 11.

[0042] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A temperature-controlled magnetic stirring automatic derivatization reaction device, characterized in that: It includes a digital display base (1), the digital display base (1) is equipped with a timing alarm device inside, and a reaction mechanism is provided on the upper surface of the digital display base (1). The reaction mechanism is used for magnetic stirring of mixed liquid samples. The reaction mechanism includes a reaction pot (11) provided on the upper surface of the digital display base (1). A drainage mechanism is provided on one side of the reaction vessel (11). The drainage mechanism is used to drain water from the inside of the reaction vessel (11). The drainage mechanism includes a drain pipe (12) provided on one side of the reaction vessel (11). A fixing ring (13) is glued to the outer side of the upper end of the drain pipe (12). A locking pin (14) is connected to one side of the fixing ring (13). The locking pin (14) is engaged with a support block (15). The reaction vessel (11) is equipped with a heating mechanism inside, which is used to heat the liquid sample. The heating mechanism includes a heating ring (16) inside the reaction vessel (11) and a temperature probe (17) inside one side of the reaction vessel (11). The reaction vessel (11) is provided with a frame mechanism inside, which is used to store liquid sample devices. The frame mechanism includes a derivatization tube rack (2) provided inside the reaction vessel (11). Handles (21) are symmetrically arranged on both sides of the derivatization tube rack (2). Centrifuge tubes (22) are sleeved inside the derivatization tube rack (2). The upper end of the reaction vessel (11) is provided with a cover mechanism, which is used to shield light and prevent pollution. The cover mechanism includes a reaction vessel lid (3) with a retaining sleeve at the upper end of the reaction vessel (11), and a handle (31) is provided on the upper surface of the reaction vessel lid (3).

2. The temperature-controlled magnetic stirring automatic derivatization reaction device according to claim 1, characterized in that: A magnetic stir bar is fitted inside the centrifuge tube (22). A control mechanism is provided on one side of the digital display base (1). The control mechanism is used to control the switch of the digital display base (1). The control mechanism includes a display screen (4) provided on one side of the digital display base (1). A magnetic stirring switch (41) is provided on one side of the digital display base (1). A power switch (42) is provided on one side of the digital display base (1).

3. The temperature-controlled magnetic stirring automatic derivatization reaction device according to claim 1, characterized in that: The digital display base (1) is equipped with a magnetic drive device inside, and the lower end of one side of the heating ring (16) is connected to the inside of the digital display base (1).

4. The temperature-controlled magnetic stirring automatic derivatization reaction device according to claim 1, characterized in that: The reaction vessel (11) is fitted with a handle (21) inside, and a centrifuge tube (22) is fitted inside the reaction vessel (11).

5. The temperature-controlled magnetic stirring automatic derivatization reaction device according to claim 1, characterized in that: A support block (15) is provided on one side of the reaction vessel (11), and a centrifuge tube (22) is sleeved inside the heating ring (16).

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