Modularized fixing support for flower cyanine fluorescent probe

Abstract

The utility model discloses modularization fixing support of flower cyan fluorescence probe, apply in biological imaging and molecular marking technical field, the utility model discloses through this design can convenient realization fluorescence probe's fixed operation, need not complex operation to complete the clamping and taking down of probe, can through the elastic action stable adhesion probe, guarantee that probe is not easy to take place loose or displacement in the placing process, and elastic regulation characteristic can adapt to different diameter specification's fluorescence probe, avoid because fixed structure rigid too strong to cause the extrusion damage of probe, effectively protect the intactness of probe, provide the guarantee for the smooth development of subsequent detection work, can realize the up and down modularization extension and removal between two supports flexibly, and the operation process is simple and efficient, can accurate completion support's positioning between, guarantee the position accuracy after the connection of upper and lower support, can firmly fix two supports through magnetic connection, avoid appearing loose in the use process, provide support for the stable use of support whole.

Description

Technical Field

[0001] This invention belongs to the field of bioimaging and molecular labeling technology, and specifically relates to a modular fixation bracket for cyanin fluorescent probes. Background Technology

[0002] Cyanide fluorescent probes are a class of molecular probes that use cyanide compounds as fluorescent chromophores. Their design and synthesis often combine the technological developments in fields such as organic chemistry and materials science. Fluorescence properties can be modulated by modifying the molecular structure to adapt to different detection scenarios. Their main function is to interact with specific target substances (such as biomolecules, heavy metal ions, etc.) in fields such as biomedicine and environmental monitoring, and achieve qualitative identification or quantitative detection of target substances through changes in fluorescence signals (such as changes in fluorescence intensity, shifts in emission wavelength, etc.). This provides molecular-level observation and analysis tools for analytical research in related fields. Cyanide fluorescent probe holders are holders used for placing and observing cyanide fluorescent probes after sampling.

[0003] However, traditional cyanin fluorescent probe holders lack an elastic fitting structure when fixing probes, resulting in poor probe fixation stability. They are prone to loosening or displacement during placement, cannot adapt to fluorescent probes of different diameters, and are easily damaged by rigid compression, compromising the integrity of the probes and potentially hindering the smooth progress of subsequent detection work. Furthermore, modular expansion and disassembly between holders are difficult, making operation inconvenient and inflexible. The lack of a precise positioning structure when connecting holders makes it difficult to ensure the accuracy of the position after connecting the upper and lower holders, thus leading to insufficient adaptability and reliability in various application scenarios.

[0004] To address the issues mentioned in the background, a modular fixation bracket for cyanin fluorescent probes is proposed. Utility Model Content

[0005] The purpose of this invention is to provide a modular fixing bracket for cyanin fluorescent probes, which has the advantages of multi-specification stability and modular expansion.

[0006] The above-mentioned technical objective of this utility model is achieved through the following technical solution: a modular fixing bracket for a cyanin fluorescence probe, including a frame, a placement groove is provided in the middle of the top of the frame, openings are provided on both sides of the inner wall of the placement groove, a spring is bolted to the inner side of the opening, a pressure roller is fixedly connected to one end of the outer side of the spring, and an expansion mechanism is provided at the edges of the four corners of the top of the frame.

[0007] The above technical solution involves placing the fluorescent probe into the placement slot at the top of the frame. During placement, the probe compresses the pressure rollers at the openings on both sides of the inner wall of the placement slot. The pressure rollers, under pressure, push the inner spring to undergo elastic deformation. The reaction force generated by the spring deformation causes the pressure rollers to tightly adhere to the probe surface, thus stably fixing the probe in the placement slot. To remove the probe, simply pull it out; the spring's return causes the mechanism to return to its original position. This design facilitates the fixing of the fluorescent probe, eliminating the need for complex operations. It provides a stable fit through elasticity, ensuring the probe is not easily loosened or displaced during placement. The elastic adjustment characteristic can accommodate fluorescent probes of different diameters, preventing damage caused by excessive rigidity of the fixing structure and effectively protecting the probe's integrity, thus ensuring the smooth progress of subsequent testing.

[0008] The present invention is further configured such that the extension mechanism includes a plug rod, the plug rod is fixedly sleeved at the edges of the four corners of the top of the frame, and slots are provided at the edges of the four corners of the bottom of the frame, with magnets embedded in the top of the slots.

[0009] The above technical solution employs an expansion mechanism. To modularly expand the bracket vertically, align the slot at the bottom of one bracket with the rod at the top of the other, insert the rod into the slot, and the magnet embedded in the top of the slot will attract the rod, thus achieving a stable connection between the two brackets. To disassemble, apply external force to overcome the magnet's attraction and pull the rod out of the slot to separate the two brackets. This design allows for flexible vertical modular expansion and disassembly of the two brackets, with a simple and efficient operation process. It accurately positions the brackets, ensuring the accuracy of the connected positions. The magnetic connection firmly fixes the two brackets, preventing loosening during use and providing support for the overall stable use of the bracket, further enhancing the flexibility and reliability of the modular fixed bracket.

[0010] The present invention is further configured such that a telescopic rod is sleeved inside the spring.

[0011] The above technical solution uses a telescopic rod to limit the movement of the spring.

[0012] The present invention is further configured such that a protective pad is fitted onto the surface of the pressure roller.

[0013] The above technical solution, by setting a protective pad, can prevent the pressure roller from damaging the probe surface.

[0014] The present invention is further configured such that a base support is fixedly sleeved on the surface of the insertion rod.

[0015] The above technical solution, by setting a base support, can stabilize the top frame when two frames are stacked and expanded.

[0016] The present invention is further configured such that the insertion rod is made of metal.

[0017] By adopting the above technical solution, by making it a metal material, the insertion rod can be magnetically connected and fixed to the magnet.

[0018] The present invention is further provided that an anti-slip pad is adhered to the bottom of the frame.

[0019] The above technical solution, by setting anti-slip mats, can prevent the frame from slipping when placed.

[0020] The present invention is further provided that the edges of the four corners of the bottom of the anti-slip mat are grooved.

[0021] The above technical solution, by setting a slot, can prevent interference with the insertion of the plug rod into the slot.

[0022] In summary, this utility model has the following beneficial effects: 1. This utility model can conveniently realize the fixing operation of fluorescent probes through this design. The clamping and removal of probes can be completed without complicated operations. It can stably fit the probe through elasticity, ensuring that the probe is not easy to loosen or shift during placement. The elastic adjustment characteristics can be adapted to fluorescent probes of different diameters and specifications, avoiding squeezing damage to the probe due to excessive rigidity of the fixing structure, effectively protecting the integrity of the probe, and providing a guarantee for the smooth progress of subsequent detection work. 2. This utility model, through its design, enables flexible expansion and disassembly of two modular supports. The operation process is simple and efficient, and the positioning between the supports can be accurately completed, ensuring the accuracy of the position after the upper and lower supports are connected. The magnetic connection can firmly fix the two supports, preventing loosening during use and providing support for the stable use of the entire support, further improving the flexibility and reliability of the modular fixed support. Attached Figure Description

[0023] Figure 1 This is a schematic diagram of the overall structure of this utility model; Figure 2 This is a partial front sectional view of the structure of this utility model; Figure 3 This is a utility model Figure 2 Enlarged schematic diagram of the structure at point A; Figure 4 This is a front sectional view of the overall structure of this utility model.

[0024] Reference numerals in the attached diagram: 1. Frame; 2. Placement slot; 3. Opening; 4. Spring; 5. Pressure roller; 6. Insert rod; 7. Slot; 8. Magnet; 9. Telescopic rod; 10. Protective pad; 11. Base support; 12. Anti-slip pad; 13. Slot. Detailed Implementation

[0025] The present invention will be further described in detail below with reference to the accompanying drawings.

[0026] Example 1: refer to Figure 1 , Figure 2 , Figure 3 , Figure 4 A modular fixing bracket for a cyanin fluorescent probe includes a frame 1. The frame 1 has a placement groove 2 in the middle of its top. Openings 3 are located on both sides of the inner wall of the placement groove 2. A spring 4 with a stiffness of 8-15 N / mm is bolted to the inner side of each opening 3. A pressure roller 5 is fixedly connected to one end of the outer side of the spring 4. An expansion mechanism is provided at the four corners of the top of the frame 1. When the fluorescent probe is placed into the placement groove 2 at the top of the frame 1, the probe will press against the pressure rollers 5 at the openings 3 on both sides of the inner wall of the placement groove 2. The pressure rollers 5, under pressure, push the inner spring 4 to undergo elastic deformation. The reaction force generated by the deformation of the spring 4 will cause the pressure rollers 5 to fit tightly against the probe surface, thus stably fixing the probe in the placement groove 2. When it needs to be removed, simply pull out the probe, and the spring 4 will spring back, causing the mechanism to return to its original state.

[0027] refer to Figure 2 , Figure 3 The spring 4 has a telescopic rod 9 inside, which can limit the movement of the spring 4.

[0028] refer to Figure 2 , Figure 3 The surface of the pressure roller 5 is fitted with a protective pad 10. By setting the protective pad 10, the pressure roller 5 can be prevented from damaging the probe surface. The material is silicone.

[0029] Example 2: refer to Figure 1 , Figure 2 , Figure 4The modular fixing bracket for the cyanin fluorescence probe includes an expansion mechanism comprising insert rods 6. The insert rods 6 are fixedly sleeved at the four corners of the top of the bracket 1. The four corners of the bottom of the bracket 1 have slots 7. The top of the slots 7 is embedded with magnets 8. If the bracket needs to be expanded vertically in a modular manner, the slot 7 at the bottom of one bracket 1 is aligned with the insert rod 6 at the top of the other bracket 1, and then the insert rod 6 is inserted into the slot 7. The magnets 8 embedded in the top of the slot 7 will generate a magnetic attraction, attracting the inserted insert rod 6, thereby achieving a stable connection between the two brackets 1. If it needs to be removed, an external force is applied to overcome the magnetic attraction of the magnets 8, and the insert rod 6 is pulled out of the slot 7 to separate the two brackets 1.

[0030] refer to Figure 1 , Figure 2 , Figure 4 The surface of the insertion rod 6 is fixedly fitted with a base support 11. By setting the base support 11, the top frame 1 can be stabilized when the two frames 1 are stacked and expanded.

[0031] refer to Figure 1 , Figure 2 , Figure 4 The insertion rod 6 is made of metal. By making it of metal, the insertion rod 6 can be magnetically connected and fixed to the magnet 8. The material is 45 steel.

[0032] refer to Figure 1 , Figure 2 , Figure 4 The bottom of the frame 1 is glued with an anti-slip pad 12. By setting the anti-slip pad 12, the frame 1 can be prevented from slipping when placed. The material is nitrile rubber.

[0033] refer to Figure 4 The anti-slip pad 12 has grooves 13 at the four corners of its bottom edge. By setting the grooves 13, it can prevent interference with the insertion of the plug rod 6 into the slot 7.

[0034] Brief description of the usage process: First, place the fluorescent probe into the placement slot 2 at the top of the frame 1. During the insertion process, the probe will press the pressure rollers 5 at the openings 3 on both sides of the inner wall of the placement slot 2. After the pressure rollers 5 are subjected to force, the inner spring 4 will undergo elastic deformation. The reaction force generated by the deformation of the spring 4 will cause the pressure rollers 5 to fit tightly against the probe surface, thereby stabilizing the probe in the placement slot 2. When it is necessary to remove it, simply pull out the probe. The spring 4 will rebound and drive the mechanism to return to its original state. If it is necessary to expand the bracket into upper and lower modular sections, align the slot 7 at the bottom of one frame 1 with the insertion rod 6 at the top of the other frame 1. Then, insert the insertion rod 6 into the slot 7. The magnet 8 embedded in the top of the slot 7 will generate a magnetic attraction, attracting the inserted insertion rod 6, thereby achieving a stable connection between the two frames 1. If it is necessary to disassemble, apply external force to overcome the magnetic attraction of the magnet 8 and pull the insertion rod 6 out of the slot 7 to separate the two frames 1.

[0035] It should be noted that parts have a lifespan and can be replaced during regular maintenance when they no longer meet performance requirements. Deterioration in performance due to prolonged use of parts is not a design defect of this application.

[0036] This specific embodiment is merely an explanation of the present utility model and is not intended to limit the present utility model. After reading this specification, those skilled in the art can make modifications to this embodiment without contributing any inventive step, but as long as they are within the scope of the claims of the present utility model, they are protected by patent law.

Claims

1. A modular fixing bracket for a cyanin fluorescent probe, comprising a frame (1), characterized in that: The top of the frame (1) has a placement groove (2) in the middle, and openings (3) are provided on both sides of the inner wall of the placement groove (2). A spring (4) is bolted to the inner side of the opening (3), and a pressure wheel (5) is fixedly connected to one end of the outer side of the spring (4). An extension mechanism is provided at the edges of the four corners of the top of the frame (1).

2. The modular fixing bracket for the cyanin fluorescent probe according to claim 1, characterized in that: The extension mechanism includes a plug (6), which is fixedly sleeved at the edges of the four corners of the top of the frame (1). The edges of the four corners of the bottom of the frame (1) are provided with slots (7), and magnets (8) are embedded in the top of the slots (7).

3. The modular fixing bracket for the cyanin fluorescent probe according to claim 1, characterized in that: The spring (4) has a telescopic rod (9) sleeved inside.

4. The modular fixing bracket for the cyanin fluorescent probe according to claim 1, characterized in that: The surface of the pressure roller (5) is fitted with a protective pad (10).

5. The modular fixing bracket for the cyanin fluorescent probe according to claim 2, characterized in that: The bottom support (11) is fixedly sleeved on the surface of the insertion rod (6).

6. The modular fixing bracket for the cyanin fluorescent probe according to claim 2, characterized in that: The insertion rod (6) is made of metal.

7. The modular fixing bracket for the cyanin fluorescent probe according to claim 1, characterized in that: The bottom of the frame (1) is glued with an anti-slip pad (12).

8. The modular fixing bracket for the cyanin fluorescent probe according to claim 7, characterized in that: The anti-slip mat (12) has grooves (13) at the four corners of its bottom edge.

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