Injection mold for PCR plates

Abstract

The utility model relates to PCR plate technical field especially, more particularly to a kind of injection mould for PCR plate;Including fixed mould plate, movable mould plate, the inside of fixed mould and the inside of movable mould are uniformly provided with profiled cooling waterway, the path of profiled cooling waterway and the profile of PCR plate injection cavity keep constant distance;The utility model is profiled cooling waterway by being set, so that cooling waterway is like a "uniform cold jacket" to wrap entire cavity, profiled cooling waterway is same with every place of injection cavity distance, ensure that heat is synchronously, uniformly taken away, the warpage of PCR plate is significantly reduced, the size consistency and perpendicularity of all micropore are guaranteed.

Description

Technical fields:

[0001] This utility model relates to the field of PCR plate technology, and in particular to an injection mold for PCR plates. Background technology:

[0002] PCR plates are used in polymerase chain reaction (PCR) as carriers for primers, Taq DNA polymerase, dNTPs, template nucleic acids, Mg, buffer, etc., which are mainly involved in the amplification reaction. Currently, PCR plates are generally injection molded. Because PCR plates have high requirements for the uniformity of heat conduction between wells, uneven cooling during injection molding can easily lead to product deformation and affect the finished product. Therefore, there is an urgent need for an injection mold with good cooling effect. Utility model content:

[0003] The purpose of this invention is to provide an injection mold for PCR plates that addresses the shortcomings of existing technologies and ensures uniform cooling.

[0004] To achieve the above objectives, the technical solution adopted by this utility model is as follows: an injection mold for a PCR plate, comprising a fixed mold plate and a movable mold plate, wherein a fixed mold core is provided on the fixed mold plate, and a PCR plate substrate cavity is provided inside the fixed mold core; a movable mold core is provided on the movable mold plate, and a PCR plate microporous cavity is provided inside the movable mold core; the PCR plate substrate cavity and the PCR plate microporous cavity are fitted together to form a PCR plate injection cavity; both the fixed mold core and the movable mold core are provided with contoured cooling water channels, and the path of the contoured cooling water channels maintains a constant distance from the contour of the PCR plate injection cavity.

[0005] A further improvement to the above scheme is that the contoured cooling water channel includes a first contoured water channel, which is disposed above the injection cavity of the PCR plate, and the direction of the first contoured water channel is adapted to the top contour of the PCR plate substrate cavity.

[0006] A further improvement to the above scheme is that the contoured cooling water channel includes a second contoured water channel, which is located below the injection cavity of the PCR plate. The path of the second contoured water channel surrounds the bottom of the microporous cavity of the PCR plate and is adapted to the bottom contour of the microporous cavity of the PCR plate.

[0007] A further improvement to the above scheme is that the cross-sectional shape of the contoured cooling water channel is set to be circular or elliptical.

[0008] A further improvement to the above scheme is that the inner wall of the contoured cooling water channel is polished, and the surface roughness of the inner wall is no greater than 0.8μm.

[0009] A further improvement to the above solution is that the contoured cooling water channel is integrally formed within the fixed mold core and the moving mold core using a metal additive manufacturing process.

[0010] A further improvement to the above scheme is that the inlet and outlet of the contour-following cooling water circuit are respectively connected to an external temperature control device.

[0011] The beneficial effects of this utility model are as follows: This utility model includes a fixed template and a movable template. The fixed template is provided with a fixed mold core, and a PCR plate substrate cavity is provided inside the fixed mold core. The movable template is provided with a movable mold core, and a PCR plate microporous cavity is provided inside the movable mold core. The PCR plate substrate cavity and the PCR plate microporous cavity are fitted together to form a PCR plate injection cavity. A contoured cooling water channel is provided inside both the fixed mold core and the movable mold core. The path of the contoured cooling water channel maintains a constant distance from the contour of the PCR plate injection cavity.

[0012] This invention features a contoured cooling water channel that acts as a uniform cooling jacket, enveloping the entire mold cavity. The channel is equidistant from every point in the injection cavity, ensuring that heat is carried away synchronously and evenly. This significantly reduces the warpage of the PCR plate and guarantees the dimensional consistency and perpendicularity of all micropores. Furthermore, contoured cooling water channels at constant distances from the cavity are installed in both the fixed and moving mold cores, enabling simultaneous contoured cooling of the top (substrate) and bottom (micropore array) surfaces of the PCR plate. This avoids stress asymmetry caused by single-sided cooling, maximizing cooling efficiency and significantly shortening the cooling time required for injection molding, directly improving production efficiency. Attached image description:

[0013] Figure 1 This is a schematic diagram of the structure of this utility model.

[0014] Figure 2 This is a cross-sectional view of the present invention.

[0015] Figure 3 for Figure 2 Enlarged view of point A in the middle.

[0016] Explanation of reference numerals in the attached drawings: Fixed template 1, Fixed mold core 11, PCR plate base plate cavity 12, Moving template 2, Moving mold core 21, PCR plate micro-well cavity 22, PCR plate injection cavity 3, Contouring cooling water channel 4, First contouring water channel 41, Second contouring water channel 42. Detailed implementation method:

[0017] The present invention will be further described below with reference to the accompanying drawings, such as... Figure 1-3As shown, this utility model provides an injection mold for a PCR plate, including a fixed mold plate 1 and a movable mold plate 2. The fixed mold plate 1 has a fixed mold core 11, and a PCR plate substrate cavity 12 is provided within the fixed mold core 11. The movable mold plate 2 has a movable mold core 21, and a PCR plate microporous cavity 22 is provided within the movable mold core 21. The PCR plate substrate cavity 12 and the PCR plate microporous cavity 22 are fitted together to form a PCR plate injection cavity 3. Contouring cooling water channels 4 are provided inside both the fixed mold core 11 and the movable mold core 21. The path of the contouring cooling water channels 4 maintains a constant distance from the contour of the PCR plate injection cavity 3. By providing the contouring cooling water channels 4, cooling... The water channel acts like a "uniform cooling jacket" enveloping the entire cavity. The contour cooling water channel 4 is equidistant from every part of the injection cavity, ensuring that heat is carried away synchronously and uniformly. This significantly reduces the warpage of the PCR plate and guarantees the size consistency and perpendicularity of all micropores. At the same time, both the fixed mold core 11 and the moving mold core 21 are equipped with contour cooling water channels 4 at a constant distance from the cavity. This allows for simultaneous contour cooling of the two main heat dissipation surfaces of the PCR plate: the top substrate and the bottom micropore array. This avoids stress asymmetry caused by single-sided cooling, maximizes cooling efficiency, and thus significantly shortens the cooling time required for injection molding, directly improving production efficiency.

[0018] The present invention includes a first contoured cooling water channel 41, which is disposed above the injection cavity 3 of the PCR plate. The direction of the first contoured cooling water channel 41 is adapted to the top contour of the PCR plate substrate cavity 12. The first contoured cooling water channel 41 precisely fits the substrate contour, realizing efficient face-to-face cooling of this area, quickly eliminating heat concentration inside the substrate, and preventing the PCR plate from warping towards the fixed mold side due to slow top cooling.

[0019] The present invention includes a second contoured cooling water channel 42, which is located below the injection cavity 3 of the PCR plate. The path of the second contoured cooling water channel 42 surrounds the bottom of the microporous cavity 22 of the PCR plate and conforms to the bottom contour of the microporous cavity 22 of the PCR plate. The second contoured cooling water channel 42 directly surrounds the root of each core, ensuring that all cores are cooled at almost the same rate, effectively eliminating the differences between the micropores and local stress caused by the different cooling rates of the micropores, and greatly improving the consistency of hundreds of micropores.

[0020] The cross-sectional shape of the contour-following cooling water channel 4 of this utility model is set to be circular or elliptical.

[0021] The inner wall of the contoured cooling water channel 4 of this utility model is polished and the surface roughness of the inner wall is no more than 0.8μm. The smooth inner wall greatly reduces the flow resistance of the coolant and makes it easy to form efficient turbulence, thereby improving the overall cooling performance. At the same time, the smooth surface is not easy to adhere to scale and impurities, and the water channel can be kept unobstructed even after long-term use, avoiding the problem of reduced cooling efficiency caused by scale accumulation.

[0022] The novel contoured cooling water channel 4 is integrally formed within the fixed mold core 11 and the moving mold core 21 using a metal additive manufacturing process. This process enables the fabrication of complex contoured cooling water channels 4 that conform to the shape and contour of a PCR plate. The integral forming process avoids the leakage risks that may result from segmented processing and subsequent assembly.

[0023] The inlet and outlet of the contour cooling water channel 4 of this utility model are respectively connected to an external temperature control device. Water valves are installed at both the inlet and outlet of the contour cooling water channel 4 of this utility model to control the flow of cooling liquid. The external temperature control device can be set as an industrial chiller, and the mold cooling temperature can be set according to the characteristics of the injection molding raw material to stabilize product quality.

[0024] Of course, the above description is only a preferred embodiment of the present utility model. Therefore, all equivalent changes or modifications made to the structure, features and principles described in the claims of the present utility model patent application are included in the scope of the present utility model patent application.

Claims

1. An injection mold for a PCR plate comprising a fixed mold plate (1), a movable mold plate (2), characterized in that: The fixed template (1) is provided with a fixed mold core (11), and the fixed mold core (11) is provided with a PCR plate substrate cavity (12). The moving template (2) is provided with a moving mold core (21), and the moving mold core (21) is provided with a PCR plate micro-well cavity (22). The PCR plate substrate cavity (12) and the PCR plate micro-well cavity (22) are combined to form a PCR plate injection cavity (3). The fixed mold core (11) and the moving mold core (21) are both provided with contoured cooling water channels (4). The path of the contoured cooling water channels (4) maintains a constant distance from the outline of the PCR plate injection cavity (3).

2. The injection mold for a PCR plate according to claim 1, characterized in that: The contoured cooling water channel (4) includes a first contoured water channel (41), which is located above the injection cavity (3) of the PCR plate. The direction of the first contoured water channel (41) is adapted to the top contour of the PCR plate substrate cavity (12).

3. The injection mold for a PCR plate according to claim 1, characterized in that: The contoured cooling water channel (4) includes a second contoured water channel (42), which is located below the injection cavity (3) of the PCR plate. The path of the second contoured water channel (42) surrounds the bottom of the microporous cavity (22) of the PCR plate and is adapted to the bottom contour of the microporous cavity (22) of the PCR plate.

4. The injection mold for a PCR plate of claim 1, wherein: The cross-sectional shape of the contoured cooling water channel (4) is set to be circular or elliptical.

5. The injection mold for a PCR plate according to claim 1, characterized in that: The inner wall of the contoured cooling water channel (4) is polished and the surface roughness of the inner wall is no greater than 0.8 μm.

6. The injection mold for a PCR plate of claim 1, wherein: The contoured cooling water channel (4) is integrally formed within the fixed mold core (11) and the moving mold core (21) using a metal additive manufacturing process.

7. The injection mold for a PCR plate of claim 1, wherein: The inlet and outlet of the contour cooling water channel (4) are respectively connected to an external temperature control device.

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